Autres inhibiteurs
Cette catégorie englobe une grande variété d'inhibiteurs qui ne rentrent pas dans les classifications standard mais qui sont néanmoins cruciaux pour diverses recherches biochimiques et pharmacologiques. Ces inhibiteurs peuvent cibler des voies, des enzymes et des interactions moléculaires uniques ou moins étudiés, fournissant des outils précieux pour des domaines de recherche spécialisés. Chez CymitQuimica, nous offrons une sélection diversifiée d'inhibiteurs de haute qualité ciblant de multiples objectifs biologiques et disciplines de recherche, vous permettant d'explorer de nouvelles avenues thérapeutiques et d'approfondir votre compréhension des processus biologiques complexes.
37853 produits trouvés pour "Autres inhibiteurs"
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Epicillin
CAS :<p>Epicillin possesses antibacterial activity.</p>Formule :C16H21N3O4SCouleur et forme :SolidMasse moléculaire :351.421Encephalitic alphavirus-IN-1
<p>Alphavirus-IN-1 blocks VEEV (EC50: 0.24 μM) & EEEV (EC50: 0.16 μM), non-toxic, stable in mice plasma.</p>Formule :C27H25FN6O2Couleur et forme :SolidMasse moléculaire :484.52PI3K-IN-26
CAS :<p>PI3K-IN-26 is an effective PI3K inhibitor. PI3K-IN-26 inhibits the proliferation of SU-DHL-6 cells, IC50= 36 nM.</p>Formule :C21H18N6OSCouleur et forme :SolidMasse moléculaire :402.47FCE-27262
CAS :<p>FCE-27262 is a prostaglandin H2/thromboxane A2 receptor antagonist.</p>Formule :C23H31N3O3Couleur et forme :SolidMasse moléculaire :397.51Antibacterial agent 69
<p>Antibacterial agent 69 is a novel structural antimicrobial modulator that can be used against lethal multidrug-resistant bacterial infections (MIC: 2.978 μM).</p>Formule :C24H19N3O4SCouleur et forme :SolidMasse moléculaire :445.49GSK699
CAS :<p>GSK699 is a potent, cell penetrant PCAF/GCN5 PROTAC.</p>Formule :C45H51BrN8O7Couleur et forme :SolidMasse moléculaire :895.84IMR687
CAS :<p>IMR687: a PDE9 inhibitor that could improve memory in Alzheimer's by slowing cGMP hydrolysis.</p>Formule :C21H26N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :394.47Mycinamicin Ⅵ
CAS :<p>Mycinamicin VI is a macrolide antibiotic with antibacterial activity against Gram-positive bacteria.</p>Formule :C35H57NO11Couleur et forme :SolidMasse moléculaire :667.83AM-3189
CAS :<p>AM-3189: potent, selective GPR40 agonist with low CNS penetration, good pharmacokinetics, and efficacy mirroring AMG 837.</p>Formule :C27H25ClN2O3Couleur et forme :SolidMasse moléculaire :460.95FR-900482
CAS :FR-900482 exhibits high sensitivity to Thermoactinomyces calidolactis strain C 953 and demonstrates activity against cell lines such as P388, B16, EL4, FM3A, L1210, BHK-21, among others.Formule :C14H15N3O6Couleur et forme :SolidMasse moléculaire :321.29AKR1C3-IN-8
<p>AKR1C3-IN-8 (Compound 5) is an effective and selective AKR1C3 inhibitor (IC50=0.069 μM). AKR1C3-IN-8 has antitumor activity.</p>Formule :C23H20N4O3Couleur et forme :SolidMasse moléculaire :400.43RK-582
CAS :<p>RK-582: oral spiroindolinone tankyrase inhibitor, halts colon cancer growth in COLO-320DM mouse model.</p>Formule :C27H35FN6O3Couleur et forme :SolidMasse moléculaire :510.6Peridinin
CAS :<p>Peridinin is an exceptionally potent and membrane-embedded inhibitor of bilayer lipid peroxidation.</p>Formule :C39H50O7Couleur et forme :SolidMasse moléculaire :630.81DAD dichloride
<p>DAD dichloride is a 3rd-gen photoelectric switch, blocks K+ channels, and helps in visual function research.</p>Formule :C26H42Cl2N6OCouleur et forme :SolidMasse moléculaire :525.56Lycopodine
CAS :<p>Lycopodine, a bioactive compound derived from Lycopodium clavatum spores, effectively inhibits the proliferation of HeLa cells through the induction of</p>Formule :C16H25NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :247.38Dictyopanine A
CAS :Dictyopanine A exhibits a relatively narrow antibacterial spectrum, demonstrating moderate antimicrobial activity only against certain filamentous fungi and Gram-positive bacteria.Formule :C25H34O5Couleur et forme :SolidMasse moléculaire :414.53Cilobamine (free base)
CAS :<p>Cilobamine: a stimulant antidepressant, inhibits norepinephrine-dopamine reuptake, based on dichloroisoprenaline structure.</p>Formule :C17H23Cl2NOCouleur et forme :SolidMasse moléculaire :328.28TTK inhibitor 3
CAS :<p>TTK inhibitor 3 is a potent and selective TTK (an essential spindle assembly checkpoint enzyme) inhibitor with an IC 50 value of 3.0 nM.</p>Formule :C42H49N9O3Couleur et forme :SolidMasse moléculaire :727.95-Deoxygentamicin C1
CAS :<p>5-Deoxygentamicin C1 exhibits activity against both gram-positive and gram-negative bacteria.</p>Formule :C21H43N5O6Couleur et forme :SolidMasse moléculaire :461.60Neoenactin M2
CAS :<p>Neoenactin M2 exhibits strong antifungal activity against yeasts and filamentous fungi.</p>Formule :C19H38N2O5Couleur et forme :SolidMasse moléculaire :374.52Cacospongionolide B
CAS :<p>Cacospongionolide B from Fasciospongia cavernosa inhibits secretory phospholipase A2, curbing inflammation.</p>Formule :C25H36O4Couleur et forme :SolidMasse moléculaire :400.55AM-9514
CAS :<p>AM-9514: a potent Glucokinase activator with strong in vitro results, good pharmacokinetics, and efficacy in diabetes.</p>Formule :C18H25N5O4Couleur et forme :SolidMasse moléculaire :375.42Carazostatin
CAS :<p>Carazostatin is an antioxidant, free radical scavenger, and potent lipid peroxidation inhibitor.</p>Formule :C20H25NODegré de pureté :98%Couleur et forme :Pale Yellow SolidMasse moléculaire :295.42Saprisartan potassium
CAS :<p>Saprisartan potassium is an Angiotensin II Type 1 receptor antagonist and antihypertensive agent.</p>Formule :C25H21BrF3KN4O4SCouleur et forme :SolidMasse moléculaire :649.5218-Deoxyherboxidiene
CAS :<p>18-Deoxyherboxidiene (RQN-18690A) inhibits angiogenesis, targeting SF3b in U2 snRNP spliceosome, affects HUVEC, useful for cancer research.</p>Formule :C25H42O5Couleur et forme :SolidMasse moléculaire :422.6TCMDC-136230
<p>TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.</p>Formule :C24H34N4O2SCouleur et forme :SolidMasse moléculaire :442.62Griseolic acid C
CAS :<p>Griseolic acid C (Dihydrodeoxygriseolic acid) is an antibiotic found in the Streptomyces griseoaurantiacus SANK43894 strain. This compound is a potent inhibitor of cyclic adenosine monophosphate (cAMP) phosphodiesterase [EC 3.1.4.17], with an IC50 of 0.12 μM (enzyme sourced from rat brain tissue).</p>Formule :C14H15N5O7Couleur et forme :SolidMasse moléculaire :365.298Epiderstatin
CAS :<p>Epiderstatin is isolated from Streptomyces pulveraceus subsp. epiderstagenes; inhibits mitogenic activity of epidermal growth factor.</p>Formule :C15H20N2O4Couleur et forme :SolidMasse moléculaire :292.33Azicemicin A
CAS :<p>Azicemicin A exhibits mild antibacterial activity and shows no acute toxicity when administered via intraperitoneal injection to mice at a dosage of 150 mg/kg.</p>Formule :C23H25NO9Couleur et forme :SolidMasse moléculaire :459.446Polyozellin
CAS :<p>Polyozellin is a prolyl endopeptidase inhibitor with properties effective against inflammation, cancer, and diseases related to oxidative stress.</p>Formule :C22H14O10Couleur et forme :SolidMasse moléculaire :438.341Deoxyfuconojirimycin hydrochloride
CAS :<p>Deoxyfuconojirimycin hydrochloride acts as a specific competitive inhibitor targeting human liver α-L-fucosidase.</p>Formule :C6H14ClNO3Couleur et forme :SolidMasse moléculaire :183.63ATM-3507 trihydrochloride (1861449-70-8 free base)
<p>ATM-3507 trihydrochloride is a potent tropomyosin inhibitor (IC50s: 3.83-6.84 μM in human melanoma cell lines).</p>Formule :C37H49Cl3FN5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :721.17Crotocin
CAS :<p>Crotocin exhibits bactericidal activity against Cryptococcus neoformans, Candida albicans, and Saccharomyces cerevisiae (brewer’s yeast), but it can be inactivated by blood.</p>Formule :C19H24O5Couleur et forme :SolidMasse moléculaire :332.391Salvinorin A Propionate
CAS :<p>Salvinorin A propionate: partial KOR agonist, Ki=32.6 nM, EC50=4.7 nM; ignores μ/δ/ORL-1, non-opioid receptors; less potent analgesic vs. salvinorin A.</p>Formule :C24H30O8Couleur et forme :SolidMasse moléculaire :446.49Fusarochromanone
CAS :Fusarochromanone (FC-101) is a mycotoxin produced by Fusarium oxysporum with potent antiangiogenic, anticancer and antimalarial activities.Formule :C15H20N2O4Degré de pureté :95.31% - 96%Couleur et forme :SolidMasse moléculaire :292.33Kahweol linoleate
CAS :<p>Kahweol linoleate, a semi-synthetic from coffee, blocks osteoclast creation, fights cancerous cells, prevents DNA damage, and reduces oxidative stress.</p>Formule :C38H56O4Couleur et forme :SolidMasse moléculaire :576.85HR-546
CAS :<p>HR-546 is a prostaglandin E2 and prostaglandin F2alpha antagonist.</p>Formule :C26H44O6Couleur et forme :SolidMasse moléculaire :452.62G-9791
CAS :<p>G-9791 is an effective and selective inhibitor of group-I PAK.</p>Formule :C26H26ClFN6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :508.98Calphostin A
CAS :<p>Calphostins, from Cladosporium fungus, inhibit PKC; calphostin C is most potent, used as a biochemical tool.</p>Formule :C44H38O12Couleur et forme :SolidMasse moléculaire :758.77GR-71251
CAS :<p>GR-71251 is a Tachykinin receptor antagonist.</p>Formule :C74H105N19O13Couleur et forme :SolidMasse moléculaire :1468.74Enactin Ia
CAS :<p>Enactin Ia is found in Streptomyces roseoviridis and exhibits mild antibacterial activity.</p>Formule :C20H38N2O6Couleur et forme :SolidMasse moléculaire :402.526ASB14780
<p>ASB14780 is a 4-phenoxy derivative and an inhibitor of cytoplasmic phospholipase cPLA2α (IC50: 20 nM).</p>Couleur et forme :SolidNI-Pano
<p>NI-Pano (CH-03) is a novel hypoxia-activated KDAC inhibitor capable of O2-dependent release of the compound panobinostat.</p>Formule :C26H28N6O4Couleur et forme :SolidMasse moléculaire :488.54ZK-Thiazolidinone
CAS :<p>ZK-Thiazolidinone (TAL), ATP-competitive PLK1 inhibitor, disrupts cell division processes in vitro and in vivo, targeting human/mouse tumors.</p>Formule :C23H26F3N5O2SCouleur et forme :SolidMasse moléculaire :493.55Furaquinocin A
CAS :<p>Furaquinocin A has the ability to kill HeLa S3 and B16 melanoma cells, yet it lacks antibacterial activity.</p>Formule :C22H26O7Couleur et forme :SolidMasse moléculaire :402.438Annonin VI
CAS :<p>Annonin VI is a natural inhibitor of NADH:ubiquinone oxidoreductase.</p>Formule :C37H66O7Couleur et forme :SolidMasse moléculaire :622.92Hesperidin dihydrochalcone
CAS :Hesperidin dihydrochalcone, a non-toxic sweetener with high sweetness and low calories, exhibits multiple biological activities including anti-oxidation, liver and kidney protection, bacteriostasis, and enhancement of gastrointestinal health.Formule :C28H36O15Couleur et forme :SolidMasse moléculaire :612.58Eilatine
CAS :<p>Eilatine is a novel marine alkaloid inhibits in vitro proliferation of progenitor cells in chronic myeloid leukemia patients.</p>Formule :C24H12N4Couleur et forme :SolidMasse moléculaire :356.38Quorum Sensing-IN-1
<p>Quorum Sensing-IN-1 is a small-molecule inhibitor of quorum sensing.</p>Formule :C13H10N2O2S2Couleur et forme :SolidMasse moléculaire :290.36Lp-PLA2-IN-5
CAS :<p>Lp-PLA2-IN-5 inhibits Lp-PLA2 and PAF-AH, potentially useful in Alzheimer's and atherosclerosis studies.</p>Formule :C23H18F5N3O4Couleur et forme :SolidMasse moléculaire :495.4Gilvusmycin
CAS :<p>Gilvusmycin is an antibiotic with potent antitumor properties. It effectively inhibits the proliferation of P388, K562, A431, and MKN28 cells, with IC50 values (ng/mL) of 0.08, 0.86, 0.72, and 0.75, respectively.</p>Formule :C38H34N6O8Couleur et forme :SolidMasse moléculaire :702.712Disorazol A
CAS :<p>Disorazol A1 is a tubulin inhibitor with antifungal properties. It functions by inhibiting tubulin polymerization and disrupting microtubule formation, thereby blocking mitosis and arresting the cell cycle at the G2/M phase, which induces apoptosis. Disorazol A1 also inhibits L929 mouse fibroblasts with an IC50 value of 3 pm and causes accumulation of p53 protein in the nucleus. Disorazol A1 holds potential for cancer research.</p>Formule :C43H54N2O10Couleur et forme :SolidMasse moléculaire :758.896Chrymutasin C
CAS :<p>Chrymutasin C is a glycoside antitumor antibiotic with cytotoxic properties.</p>Formule :C39H43NO17Couleur et forme :SolidMasse moléculaire :797.755GSK2578999A
CAS :<p>GSK2578999A is a betulin derivative with antitumor activity.</p>Formule :C46H62ClNO7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :776.44Mesulergine
CAS :<p>Mesulergine is metabolized into dopaminergic agonists.</p>Formule :C18H26N4O2SCouleur et forme :SolidMasse moléculaire :362.49CGP 22979
CAS :<p>CGP 22979 is a renal selective vasodilator prodrug.</p>Formule :C16H24N4O4Couleur et forme :SolidMasse moléculaire :336.39SLN124
<p>SLN124, a GalNAc-siRNA targeting TMPRSS6, may normalize iron balance by restoring ferroregulation.</p>Couleur et forme :SolidIstamycin Y0
CAS :<p>Istamycin Y0 is an aminoglycoside antibiotic found in *Streptomyces tenjimariensis* [ATCC 31603]. This compound exhibits weak antibacterial activity against only a limited range of bacteria.</p>Formule :C14H30N4O4Couleur et forme :SolidMasse moléculaire :318.41Cystothiazole A
CAS :<p>Cystothiazole A exhibits antifungal properties, effectively inhibiting Candida albicans, Saccharomyces cerevisiae, and Aspergillus fumigatus with minimum inhibitory concentrations (MIC) of 0.4 μg/mL, 0.1 μg/mL, and 1.6 μg/mL, respectively. It also demonstrates inhibitory activity against human tumor cells such as HPT-116 and K562, with MIC values of 130 ng/mL and 110 ng/mL. However, it shows no antibacterial activity.</p>Formule :C20H26N2O4S2Couleur et forme :SolidMasse moléculaire :422.561S-1033
CAS :<p>S-1033 is an FP receptor agonist.</p>Formule :C20H33NaO4Couleur et forme :SolidMasse moléculaire :360.4698JTE 151A
CAS :<p>JTE-151 is a novel RORγ inverse agonist.</p>Formule :C26H30ClN3O5Couleur et forme :SolidMasse moléculaire :499.99hCA IX-IN-1
<p>hCA IX-IN-1 inhibits human carbonic anhydrases I, II, IX, and XII with Ki values of 331.4, 28.4, 9.4, 17.8 nM and exhibits anticancer properties.</p>Formule :C19H18N2O3SCouleur et forme :SolidMasse moléculaire :354.42MK-7445
CAS :<p>MK-7445 is a conformationally constrained inhibitor of non-nucleoside reverse transcriptase.</p>Formule :C21H13Cl2N7OCouleur et forme :SolidMasse moléculaire :450.28Pterulinic acid
CAS :<p>Pterulinic acid is an inhibitor of coenzyme I:coenzyme Q oxidoreductase. It demonstrates IC50 values (μg/mL) of 50 for the mammalian cell line L1210, 20 for HL60, 25 for HeLaS3, and 100 for BHK.</p>Formule :C15H11ClO4Couleur et forme :SolidMasse moléculaire :290.70H-Glu(4MβNA)-OH
CAS :H-Glu(4MβNA)-OH serves as a substrate for aminopeptidases (APs).Formule :C16H18N2O4Couleur et forme :SolidMasse moléculaire :302.33Neihumicin
CAS :<p>Neihumicin exhibits resistance against the yeast Saccharomyces cerevisiae (ATCC 9763) and the mold Penicillium italicum (Wehmer), but it does not show resistance to bacteria.</p>Formule :C19H16N2O2Couleur et forme :SolidMasse moléculaire :304.342NS2B/NS3-IN-5
<p>Compound 25b inhibits DENV2/ZIKV NS2B/NS3 proteases; IC50: ZIKV 0.67μM, DENV2 4.38μM.</p>Formule :C14H9IN2O3SCouleur et forme :SolidMasse moléculaire :412.2Gunacin
CAS :<p>Gunacin is a quinone antibiotic that exhibits significant activity against Gram-positive bacteria, Gram-negative bacteria, and mycoplasmas.</p>Formule :C17H16O8Couleur et forme :SolidMasse moléculaire :348.304Foroxymithine
CAS :<p>Foroxymithine is an inhibitor of angiotensin-converting enzyme.</p>Formule :C22H37N7O11Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :575.57S24-14
CAS :S24-14 serves as an effective anti-osteoporosis agent by inhibiting osteoclastogenesis, promoting osteoblast differentiation, and reducing bone resorption.Formule :C19H12N2O3SCouleur et forme :SolidMasse moléculaire :348.38VEGFR-2-IN-25
CAS :<p>VEGFR-2-IN-25 (compound 5d) is a potent inhibitor of VEGFR-2 (IC50: 12.1 nM).</p>Formule :C24H22N6O2Couleur et forme :SolidMasse moléculaire :426.47Porothramycin B
CAS :<p>Porothramycin B is an antibiotic with activity against Gram-positive bacteria and anaerobes.</p>Formule :C19H23N3O4Couleur et forme :SolidMasse moléculaire :357.404Flurdihydroergotamine
CAS :<p>Flurdihydroergotamine, a serotonin 5HT1 receptor agonist, is used as an antimigraine drug.</p>Formule :C34H36F3N5O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :651.68PLP_Snyder530
<p>PLP_Snyder530, a potent PL pro inhibitor, halts SARS-CoV-2 by triggering protease conformation changes.</p>Formule :C24H24N2O2Couleur et forme :SolidMasse moléculaire :372.46SMP-797 HCl
CAS :<p>SMP-797 HCl, an ACAT (acyl-CoA-cholesterol acyltransferase) inhibitor, is used potentially for the treatment of Hyperlipidemia.</p>Formule :C34H44ClN5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :622.20LGB-321 HCl
CAS :<p>LGB-321: potent, selective PIM kinase inhibitor, active against PIM2, halts diverse blood cancers' growth, orally effective in mice.</p>Formule :C23H23ClF3N5O2Couleur et forme :SolidMasse moléculaire :493.91Feudomycin B
CAS :<p>Feudomycin B is a macrolactam antibiotic that exhibits antitumor cell activity.</p>Formule :C28H31NO10Couleur et forme :SolidMasse moléculaire :541.546TRPC5-IN-4
CAS :<p>TRPC5-IN-4: Potent, safe inhibitor; IC50 14.07 nM (TRPC5), 65 nM (TRPC4); non-toxic to liver/kidney cells; for CKD research.</p>Formule :C18H11ClF4N4O3Couleur et forme :SolidMasse moléculaire :442.75Granaticin B
CAS :<p>Granaticin B inhibits the initial phase of RNA biosynthesis and exhibits activity against Gram-positive bacteria, mycobacteria (weak), and Trichomonas vaginalis, along with the ability to suppress tumor cells.</p>Formule :C28H30O12Couleur et forme :SolidMasse moléculaire :558.531YM-202074
CAS :<p>YM-202074: Selective mGlu1 antagonist, binds allosteric site (Ki=4.8 nM), inhibits mGlu1 (IC50=8.6 nM).</p>Formule :C22H30N4O2SCouleur et forme :SolidMasse moléculaire :414.56MEIS-IN-2
<p>MEIS-IN-2 is an inhibitor of MEIS1. MEIS-IN-2 can be used in studies of cardiac regeneration and haematopoietic stem cell (HSC) regulation.</p>Formule :C23H21ClN2O4Couleur et forme :SolidMasse moléculaire :424.887β,16α-Dihydroxybufalin
CAS :<p>7β,16α-Dihydroxybufalin, a dihydroxylated derivative of bufalin, demonstrates cytotoxic properties against various cancer cell lines.</p>Formule :C24H34O6Couleur et forme :SolidMasse moléculaire :418.52D18
CAS :<p>D18: Dual agonist for TLR7/8, boosts PD-L1, aids tumor sensitivity to PD-1/PD-L1 inhibitors, and is a cytotoxin for ADC HE-S2.</p>Formule :C21H28N6Couleur et forme :SolidMasse moléculaire :364.49SS-RJW100
<p>SS-RJW100 is an enantiomer of RJW100 targeting LRH-1, SF-1, enhances Tif2 interaction, and disrupts LRH-1 networks with lowered stability.</p>Formule :C28H34OCouleur et forme :SolidMasse moléculaire :386.57FR 901537
CAS :<p>FR 901537 is a new aromatase inhibitor with antitumor effects.</p>Formule :C23H29N3O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :507.62Lorajmine
CAS :Lorajmine, a monochloroacetyl derivative of ajmaline, is a class Ia antiarrhythmic agent that is rapidly hydrolyzed to ajmaline by plasma and tissue esterases.Formule :C22H27ClN2O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.91Dinordrin I diacetate
CAS :<p>Dinordrin I diacetate is an implantation inhibitor and hormone.</p>Formule :C25H32O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :396.52Alentemol hydrobromide
CAS :<p>Alentemol hydrobromide is a Dopamine agonist.</p>Formule :C19H26BrNODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :364.3211-Demethyltomaymycin
CAS :<p>11-Demethyltomaymycin is an antibiotic that exhibits antiviral activity against Escherichia coli T1 and T3 bacteriophages, along with antibacterial properties against Gram-positive bacteria. Furthermore, it shows cytotoxic effects on leukemia L1210 cells.</p>Formule :C15H18N2O4Couleur et forme :SolidMasse moléculaire :290.314Feigrisolide C
CAS :<p>Feigrisolide C is a lactone produced by the bacterium Streptomyces griseus.</p>Formule :C21H36O7Couleur et forme :SolidMasse moléculaire :400.506Deoxyfrenolicin
CAS :<p>Deoxyfrenolicin is a quinone antibiotic that can be isolated from the fermentation broth of the Streptomyces roseofulvus strain AM-3867 and belongs to the frenolicin class of antibiotics. This compound exhibits in vitro antibacterial activity and is effective in inhibiting the activity of Mycoplasma gallisepticum.</p>Formule :C18H18O6Couleur et forme :SolidMasse moléculaire :330.332Pochonin D
CAS :<p>Pochonin D is an inhibitor of heat shock protein 90 (Hsp90) with antiviral and anti-inflammatory properties. It disrupts Hsp90, affecting the stability, folding, and assembly of viral proteins, thereby diminishing viral replication. Additionally, Pochonin D reduces the infiltration of inflammatory cells and decreases the secretion of inflammatory cytokines such as TNF-α and IL-1β, alleviating inflammatory responses. This compound shows potential for research in human rhinovirus (HRV) infections and cancer.</p>Formule :C18H19ClO5Couleur et forme :SolidMasse moléculaire :350.793BXL0124
CAS :<p>BXL0124 is a gemini vitamin D analog which targets CD44-STAT3 signaling and inhibits breast cancer invasion.</p>Formule :C32H44F6O4Couleur et forme :SolidMasse moléculaire :606.68BAY-850 HCl
<p>BAY-850 is a selective probe targeting Atad2A's bromine domain, displacing acetylated H4 peptides and detaching ATAD2 from chromatin at 1μm.</p>Formule :C38H48Cl5N5O3Couleur et forme :SolidMasse moléculaire :800.08Cinnabarin
CAS :<p>Cinnabarin is an antibiotic obtained from Polystiotus cinnabarinus, P. versicolo, and Trametes cinnabarinus. It exhibits antibacterial activity against Gram-positive bacteria and demonstrates antiviral properties, making it a promising candidate for research in infectious diseases.</p>Formule :C14H10N2O5Couleur et forme :SolidMasse moléculaire :286.24Ascofuranone
CAS :<p>Ascofuranone is an inhibitor of the ubiquinol oxidase activity of Trypanosoma brucei mitochondrial alternative oxidase (TAO), as well as an inhibitor of HsDHODH</p>Formule :C23H29ClO5Couleur et forme :SolidMasse moléculaire :420.93Barixibat
CAS :<p>Barixibat is a bile acid transport inhibitor.</p>Formule :C42H55N5O8Couleur et forme :SolidMasse moléculaire :757.913'-O-Decarbamoylirumamycin
CAS :<p>3'-O-Decarbamoylirumamycin is a 20-membered macrolide antibiotic produced by Streptomyces subflavus subsp. irumaensis. It exhibits inhibitory effects against plant pathogenic fungi, such as Pyricularia oryzae and Sclerotinia.</p>Formule :C40H64O11Couleur et forme :SolidMasse moléculaire :720.93Dehydroindapamide
CAS :<p>Dehydroindapamide, an indole form of Indapamide, is utilized to quantify the turnover rate of Indapamide in CYP3A4, which is approximately 10 times higher than that of Indoline, with slightly enhanced affinity for CYP3A4.</p>Formule :C16H14ClN3O3SCouleur et forme :SolidMasse moléculaire :363.82BAY-693
CAS :<p>BAY-693 is a ERK5 negative control agent with IC50 (ERK5) = 6400 nM. Its analog, BAY-885, is a potent and selective ERK5 (MAPK7) inhibitor with IC50 of 40 nM</p>Formule :C26H30F3N7O2Couleur et forme :SolidMasse moléculaire :529.56Dexnebivolol
CAS :<p>Dexnebivolol (R67138), a ß-adrenergic antagonist, is Nebivolol's enantiomer with β1 blocking and vasodilation properties.</p>Formule :C22H25F2NO4Couleur et forme :SolidMasse moléculaire :405.43Kigamicin A
CAS :<p>Kigamicin A exhibits activity against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), with a minimum inhibitory concentration (MIC) ranging from 0.025 to 0.78 μg/mL.</p>Formule :C34H35NO13Couleur et forme :SolidMasse moléculaire :665.64ROS1-IN-1
<p>ROS1-IN-1, a potent ROS1 kinase inhibitor, has an IC50 of 0.097 μM.</p>Formule :C17H15ClN6SCouleur et forme :SolidMasse moléculaire :370.86MSA-2 dimer
CAS :<p>MSA-2 dimer: selective oral non-nucleotide STING agonist, Kd=145 μM, long-term antitumor effect, non-covalent, higher permeability.</p>Formule :C29H28O8S2Couleur et forme :SolidMasse moléculaire :568.66PD-1-IN-17 TFA
<p>PD-1-IN-17 TFA is a potent PD-1 inhibitor, blocking 92% of splenocyte growth at 100 nM.</p>Formule :C15H23F3N6O9Couleur et forme :SolidMasse moléculaire :488.37Melithiazole N
CAS :<p>Melithiazol N is an antibiotic. It acts as a β-methoxyacrylate (MOA) inhibitor with potent antidrug activity.</p>Formule :C20H24N2O5S2Couleur et forme :SolidMasse moléculaire :436.545Rafutrombopag
CAS :<p>Rafutrombopag is a thrombopoietin (TPO) agonist.</p>Formule :C25H22N4O5Couleur et forme :SolidMasse moléculaire :458.47Polyoxin E
CAS :<p>Polyoxin E is a nucleoside antifungal antibiotic that demonstrates significant effectiveness against rice sheath blight.</p>Formule :C17H23N5O13Couleur et forme :SolidMasse moléculaire :505.39Purine phosphoribosyltransferase-IN-1
<p>Compound (S,R)-48 inhibits Pf, Pv, & Tbr PRT with Ki of 50, 20, 2 nM.</p>Formule :C11H15N5Na4O10P2Couleur et forme :SolidMasse moléculaire :531.172-Hydroxygentamicin B1
CAS :<p>2-Hydroxygentamicin B1 is an aminoglycoside antibiotic that exhibits activity against both Gram-positive and Gram-negative bacteria.</p>Formule :C20H40N4O11Couleur et forme :SolidMasse moléculaire :512.552rel-MDM2/4-p53-IN-2
<p>Potent dual MDM2/MDM4 inhibitor & p53 activator; IC50: 70.7 nM (MDM2), 81.4 nM (MDM4); regulates cell cycle, triggers apoptosis, anti-cancer.</p>Formule :C25H17Cl3FN3O3Couleur et forme :SolidMasse moléculaire :532.78ONO-AE1-329
CAS :<p>ONO-AE1-329 is a novel agonist of the prostaglandin PGE2 receptor EP4.</p>Formule :C22H30O6S2Couleur et forme :SolidMasse moléculaire :454.6Aplysin
CAS :<p>Aplysin suppresses breast cancer cells and protects liver cells by blocking PI3K/AKT/FOXO3a and preventing oxidative damage.</p>Formule :C15H19BrOCouleur et forme :SolidMasse moléculaire :295.21Micacocidin A
CAS :<p>Micacocidin A is an antibiotic showing excellent activity against Mycoplasma species.</p>Formule :C27H37N3O4S3ZnCouleur et forme :SolidMasse moléculaire :629.20Imolamine hydrochloride
CAS :<p>Imolamine hydrochloride is a blood platelet aggregation antagonist.</p>Formule :C14H21ClN4OCouleur et forme :SolidMasse moléculaire :296.80Milbemycin α11
CAS :<p>Milbemycin α11 (Meilingmycin A) is an antibiotic known for its ability to eliminate nematodes and mites.</p>Formule :C36H50O9Couleur et forme :SolidMasse moléculaire :626.78PARP10/15-IN-1
<p>PARP10/15-IN-1 (compound 8l) is a dual PARP10 and PARP15 inhibitor with IC50s of 160 nM and 370 nM, respectively. It can be used in cancer research[1].</p>Formule :C13H10N2O3SCouleur et forme :SolidMasse moléculaire :274.3BI-207524
CAS :<p>BI-207524 is a novel NS5B Thumb Pocket 1 Inhibitor with Improved Potency for the Potential Treatment of Chronic Hepatitis C Virus Infection.</p>Formule :C35H36ClN5O5Couleur et forme :SolidMasse moléculaire :642.14GG-43
<p>GG-43 is a potent inhibitor of LIN28. The IC50 value of GG-43 against human LIN28A is 4 μM [1].</p>Formule :C21H21NO3Couleur et forme :SolidMasse moléculaire :335.4KF 20274
CAS :<p>KF 20274 is an adenosine A1 antagonist; purinergic receptor antagonist.</p>Formule :C21H29N5OCouleur et forme :SolidMasse moléculaire :367.49Chloronectrin
CAS :<p>Chloronectrin exhibits activity against Gram-positive bacteria.</p>Formule :C25H33ClO6Couleur et forme :SolidMasse moléculaire :464.979ONO-AE1-259 lysine
CAS :<p>ONO-AE1-259 is a highly selective agonist of prostaglandin e2 receptor (ep2)</p>Formule :C28H49ClN2O6Couleur et forme :SolidMasse moléculaire :545.15TAM&Met-IN-1
CAS :<p>TAM&Met-IN-1 inhibits AXL, MER, TYRO3 with IC50s 6.1, 13.2, 21.6 nM, respectively, for cancer research.</p>Formule :C29H27F2N7O5Couleur et forme :SolidMasse moléculaire :591.57XR8-89
CAS :<p>XR8-89, a potent PLpro inhibitor (IC50=0.1μM), blocks SARS-CoV-2 replication; useful for research.</p>Formule :C29H36N4O2SCouleur et forme :SolidMasse moléculaire :504.69KCa2 channel modulator 2
Compound 2q is a potent, subtype-selective K/Ca 2 modulator, effective on human K Ca 2.3 and rat K Ca 2.2a with EC50s of 0.60 μM and 0.64 μM.Formule :C16H15ClFN5Couleur et forme :SolidMasse moléculaire :331.78FTI-2153 TFA
<p>FTI-2153 TFA inhibits farnesyltransferase with high selectivity (IC50: 1.4 nM), over 3000x more than Rap1A processing.</p>Formule :C27H31F3N4O5SCouleur et forme :SolidMasse moléculaire :580.62Lunacalcipol
CAS :<p>Lunacalcipol is used for the treatment of Secondary Hyperparathyroidism.</p>Formule :C28H42O4SCouleur et forme :SolidMasse moléculaire :474.7VU6028418
<p>VU6028418 is a highly selective, potent, orally active M4mAChR antagonist that acts on hM4 (IC50: 4.1 nM).</p>Couleur et forme :Liquid2,3-dinor-11β-Prostaglandin F2α
CAS :<p>2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where</p>Formule :C18H30O5Couleur et forme :SolidMasse moléculaire :326.43LPA5 antagonist 1
<p>LPA5 antagonist 1: selective, potent (IC50=32 nM), high brain permeability, studies inflammatory/neuropathic pain.</p>Formule :C28H26N2O4SCouleur et forme :SolidMasse moléculaire :486.58Iodinin
CAS :<p>Iodinin is an antibiotic with antibacterial and antifungal properties.</p>Formule :C12H8N2O4Couleur et forme :SolidMasse moléculaire :244.203Melanocin A
CAS :<p>Melanocin A is an inhibitor of melanin biosynthesis. It suppresses the synthesis of melanin and tyrosinase with an IC50 of 9.0 nM and MIC of 0.9 μM. Additionally, Melanocin A exhibits antioxidant properties.</p>Formule :C18H14N2O5Couleur et forme :SolidMasse moléculaire :338.31Tacrolimus anhydrous 8-epimer
CAS :<p>Tacrolimus anhydrous 8-epimer, an immunosuppressive l-pipecolic acid macrolide, blocks T cell growth by hindering IL-2.</p>Formule :C44H69NO12Couleur et forme :SolidMasse moléculaire :804.02RORγt modulator 5
CAS :<p>RORγt modulator 5, a potent RORγt modulator, exhibits a dissociation constant (K_i) of <100 nM.</p>Formule :C27H22F5N3O6SCouleur et forme :SolidMasse moléculaire :611.54ATX inhibitor 22
<p>ATX inhibitor 22 is a novel inhibitor of ATX (autotaxin) (IC50: 218.9 μM) that lacks inhibitory activity against LPAR1.</p>Formule :C19H17Cl3F2N2O4SCouleur et forme :SolidMasse moléculaire :513.77GYKI-53784
CAS :<p>GYKI-53784 (LY 303070) is an effective selective AMPA receptor antagonist.</p>Formule :C19H20N4O3Couleur et forme :SolidMasse moléculaire :352.39Nanaomycin D
CAS :<p>Nanaomycin D is an antibiotic with antibacterial properties.</p>Formule :C16H12O6Couleur et forme :SolidMasse moléculaire :300.263DS69910557
<p>DS69910557: potent hPTHR1 antagonist, IC50 0.08 μM, oral, for hyperparathyroidism & osteoporosis research.</p>Formule :C32H33Cl2FN4O3Couleur et forme :SolidMasse moléculaire :611.53Glidobactin B
CAS :<p>Glidobactin B is an antitumor antibiotic. It is active against pathogenic fungi and yeasts and can prolong the survival time of mice inoculated with leukemia P388 cells.</p>Formule :C29H46N4O6Couleur et forme :SolidMasse moléculaire :546.699WS-898
<p>WS-898 boosts paclitaxel efficacy in resistant cells by inhibiting ABCB1; IC50: SW620/Ad300 - 5.0 nM, KB-C2 - 3.67 nM, HEK293/ABCB1 - 3.68 nM.</p>Formule :C33H25N7OSCouleur et forme :SolidMasse moléculaire :567.66Antileishmanial agent-6
<p>Antileishmanial agent-6: potent against Leishmania donovani, IC50 0.54μM; cytotoxic IC50 10.2μM.</p>Formule :C24H26O8Couleur et forme :SolidMasse moléculaire :442.46Echinocandin B nucleus
CAS :<p>Echinocandin B nucleus (A-30912 A nucleus) is the reaction product catalyzed by Echinocandin B decarboxylase. It serves as an intermediate in the semisynthetic production of antifungal agents.</p>Formule :C34H51N7O15Couleur et forme :SolidMasse moléculaire :797.807Anticancer agent 35
<p>Compound 10, a sulfonylurea, inhibits A549, A431, PACA2 cells with IC50s: 18.1, 4.0, 18.9 μg/mL.</p>Formule :C15H13N3O3S3Couleur et forme :SolidMasse moléculaire :379.48GW311616
CAS :<p>GW-311616 is a long duration, orally bioavailable, and selective human neutrophil elastase (HNE) inhibitor (IC50: 22 nM; Ki: 0.31 nM).</p>Formule :C19H31N3O4SCouleur et forme :SolidMasse moléculaire :397.53Artemisiane E
CAS :<p>Artemisiane E is a potent PI3K/AKT pathway inhibitor with an IC 50 of 8.9 μM .</p>Formule :C20H22O5Couleur et forme :SolidMasse moléculaire :342.39Kerriamycin C
CAS :<p>Kerriamycin C exhibits activity against Gram-positive bacteria and also inhibits Ehrlich ascites carcinoma.</p>Formule :C37H46O15Couleur et forme :SolidMasse moléculaire :730.752Pinselin
CAS :<p>Pinselin is a nitrogen-containing heterocyclic antibiotic with yeast-inhibiting properties.</p>Formule :C16H12O6Couleur et forme :SolidMasse moléculaire :300.263Cetoniacytone B
CAS :<p>Cetoniacytone B inhibits the growth of HEPG2 and MCF7 human tumor cell lines, with a GI50 of 4.4 μM.</p>Formule :C7H9NO4Couleur et forme :SolidMasse moléculaire :171.151Eurystatin A
CAS :<p>Eurystatin A is a prolyl endopeptidase inhibitor, with L-leucine and L-ornithine serving as direct precursors to the L-leucine and L-ornithine components of eurystatins A.</p>Formule :C23H38N4O5Couleur et forme :SolidMasse moléculaire :450.572Leucomycin V
CAS :<p>Leucomycin V is a macrolide antibiotic. Leucomycin A9 exhibits strong activity against Gram-positive bacteria and also affects spirochetes, rickettsiae, and chlamydiae.</p>Formule :C35H59NO13Couleur et forme :SolidMasse moléculaire :701.842Neoenactin A
CAS :<p>Neoenactin A exhibits potent activity against yeasts and filamentous fungi.</p>Formule :C19H36N2O5Couleur et forme :SolidMasse moléculaire :372.5Megovalicin A
CAS :<p>Megovalicin A is effective against Bacillus subtilis and Escherichia coli.</p>Formule :C35H63NO8Couleur et forme :SolidMasse moléculaire :625.8820-Deoxynarasin
CAS :<p>20-Deoxynarasin exhibits activity against Gram-positive bacteria, mycoplasma, coccidia, and viruses, and it also promotes growth.</p>Formule :C43H72O10Couleur et forme :SolidMasse moléculaire :749.03Nepaprazole sodium
CAS :<p>Nepaprazole Na (TY-11345), a proton pump inhibitor, may treat gastric ulcers; it reduces H+/K(+)-ATPase activity, with IC50 of 5.8-9.9 microM.</p>Formule :C18H18N3NaO2SCouleur et forme :SolidMasse moléculaire :363.41Dinalbuphine sebacate
CAS :<p>Dinalbuphine sebacate: long-acting nalbuphine prodrug, μ-opioid partial agonist/antagonist, κ-opioid high-efficacy agonist.</p>Formule :C52H68N2O10Couleur et forme :SolidMasse moléculaire :881.1Glyphosate-trimesium
CAS :<p>Glyphosate-trimesium is a herbicide.</p>Formule :C6H16NO5PSCouleur et forme :SolidMasse moléculaire :245.23KMH-233
CAS :<p>KMH-233 effectively blocks LAT1, inhibiting L-leucine uptake and cell growth, boosting betastatin and cisplatin efficacy at 25 μM.</p>Formule :C32H25N7O5Couleur et forme :SolidMasse moléculaire :587.58Tubulosine
CAS :<p>Tubulosine is an anticancer agent that inhibits cancer cell growth.</p>Formule :C29H37N3O3Couleur et forme :SolidMasse moléculaire :475.62Flurandrenolone Acetate
CAS :<p>Flurandrenolone Acetate, a synthetic glucocorticoid derived from Flurandrenolide, is used to study skin issues like eczema and psoriasis.</p>Formule :C26H35FO7Couleur et forme :SolidMasse moléculaire :478.55BMS-986120
CAS :BMS-986120: Oral, reversible PAR4 antagonist. IC50: 9.5 nM (human), 2.1 nM (monkey). Potent, selective antiplatelet.Formule :C23H23N5O5S2Couleur et forme :SolidMasse moléculaire :513.59GSK340
<p>GSK340 is a BET inhibitor.</p>Formule :C26H31N3O2Couleur et forme :SolidMasse moléculaire :417.55Esorubicin
CAS :<p>Esorubicin, a doxorubicin derivative, intercalates DNA, inhibits topoisomerase II, has less cardiotoxicity, but more myelosuppression.</p>Formule :C27H29NO10Couleur et forme :SolidMasse moléculaire :527.52Anticancer agent 80
<p>Anticancer agent 80 (Compound 3c) is an anticancer agent that exhibits a significant dark toxic effect on T47-D (IC50: 10.14 μM).</p>Formule :C19H12BrNO5Couleur et forme :SolidMasse moléculaire :414.21YW3-56
CAS :<p>YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.</p>Formule :C27H32ClN5O2Couleur et forme :SolidMasse moléculaire :494.03TCMDC-135051 TFA (2413716-15-9 free base)
<p>TCMDC-135051 TFA is a highly selective and potent inhibitor of protein kinase PfCLK3.</p>Formule :C31H34F3N3O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :585.61Nemotin
CAS :<p>Nemotin exhibits activity against Gram-positive bacteria, mycobacteria, and fungi, while its effectiveness against Gram-negative bacteria is present but relatively weaker.</p>Formule :C11H8O2Couleur et forme :SolidMasse moléculaire :172.18Ekatetrone
CAS :<p>Ekatetrone displays activity against both Gram-positive and Gram-negative bacteria, with particularly strong inhibitory effects on Mycobacterium tuberculosis.</p>Formule :C19H13NO7Couleur et forme :SolidMasse moléculaire :367.3095(S),6(R)-DiHETE
CAS :<p>5(S),6(R)-DiHETE is a dihydroxy fatty acid from LTA4 hydrolysis and weak LTD4 agonist with ED50 of 1.3 μM for guinea pig ileum contraction.</p>Formule :C20H32O4Couleur et forme :SolidMasse moléculaire :336.47Anti-ToCV agent 1
<p>Anti-ToCV agent 1 can be used as a potential anti-ToCV drug.</p>Formule :C22H19FN2O5SCouleur et forme :SolidMasse moléculaire :442.46TP-030-1
CAS :<p>TP-030-1, RIPK1 inhibitor: K(i) hRIPK1 at 3.9nM, IC50 mRIPK1 at 4.2μM; targets inflammation, neurodegeneration research.</p>Formule :C23H22N4O3Couleur et forme :SolidMasse moléculaire :402.45AS2575959
CAS :<p>AS2575959 is a novel GPR40 agonist, exhibiting glucose metabolism improvement and synergistic effect with sitagliptin on insulin and incretin secretion.</p>Formule :C32H35NaO7Couleur et forme :SolidMasse moléculaire :554.6148H 218-54
CAS :<p>H 218-54 is a renin inhibitor.</p>Formule :C37H56N2O5SCouleur et forme :SolidMasse moléculaire :640.92Sinulatumolin E
CAS :<p>Sinulatumolin E, a terpenoid, inhibits TNF-α (IC 50: 3.6 μM); has anti-inflammatory properties.</p>Formule :C15H22O2Couleur et forme :SolidMasse moléculaire :234.33GDC-6036-NH
CAS :<p>GDC-6036-NH is a precursor of compound 17a /b, which is a RAS inhibitor that can be used in cancer research.</p>Formule :C26H30ClF4N7ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :568.0110-Hydroxyundeca-2,4,6,8-tetraynamide
CAS :<p>10-Hydroxyundeca-2,4,6,8-tetraynamide is a polyacetylene antibiotic exhibiting activity against Gram-positive and Gram-negative bacteria, yeasts, fungi, as well as cytotoxic properties.</p>Formule :C11H7NO2Couleur et forme :SolidMasse moléculaire :185.179Epelmycin C
CAS :<p>Epelmycin C exhibits antibacterial activity against both Gram-positive and Gram-negative bacteria, as well as antifungal activity against Candida albicans. It also shows activity against leukemia L1210.</p>Formule :C36H45NO14Couleur et forme :SolidMasse moléculaire :715.741Chitinovorin A
CAS :<p>Chitinovorin A is a β-lactam antibiotic (antibiotic) that exhibits weak inhibitory activity against Gram-negative bacteria.</p>Formule :C26H41N9O11SCouleur et forme :SolidMasse moléculaire :687.722Resorcinomycin A
CAS :<p>Resorcinomycin A is an antibiotic with potent antimycobacterial activity and relatively weaker activity against mycoplasma.</p>Formule :C14H20N4O5Couleur et forme :SolidMasse moléculaire :324.332GNE-616
CAS :<p>GNE-616: a potent, stable, oral Nav1.7 inhibitor; Ki: 0.79 nM, Kd: 0.38 nM; for chronic pain.</p>Formule :C24H23F4N5O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :537.53BMS-824
CAS :<p>BMS-824: potent HCV NS5A inhibitor, IC50 ~5 nM, therapeutic index >10,000, specific to HCV.</p>Formule :C27H25F3N4O5Couleur et forme :SolidMasse moléculaire :542.51Memnobotrin B
CAS :<p>Memnobotrin B is an antibiotic that exhibits inhibitory effects on the NCI-460, MCF7, and SF-268 cell lines.</p>Formule :C27H37NO6Couleur et forme :SolidMasse moléculaire :471.59Naltrindole
CAS :<p>Naltrindole is a delta opioid receptor antagonist.</p>Formule :C26H26N2O3Couleur et forme :SolidMasse moléculaire :414.5SX 3202
CAS :<p>SX 3202 is an aldose reductase inhibitor being developed for the treatment of diabetic neuropathy.</p>Formule :C17H11BrFN3O4Couleur et forme :SolidMasse moléculaire :420.194"-Demethylgentamicin C1
CAS :<p>4"-Demethylgentamicin C1 exhibits antibacterial activity against both Gram-positive and Gram-negative bacteria.</p>Formule :C20H41N5O7Couleur et forme :SolidMasse moléculaire :463.57Cyclophellitol
CAS :<p>Cyclophellitol is an inhibitor of β-glycosidase, with an IC50 of 0.8 μg/mL.</p>Formule :C7H12O5Couleur et forme :SolidMasse moléculaire :176.167PGDM
CAS :<p>PGD2 is involved in allergy, asthma, sleep, temperature regulation, inhibits clotting, and relaxes blood vessels; PGDM, its metabolite, is a biomarker.</p>Formule :C16H24O7Couleur et forme :SolidMasse moléculaire :328.36Ataprost
CAS :<p>Ataprost (ONO 41483), an oral Carboprostacyclin analogue, is 2.6x more potent in inhibiting ADP-induced platelet aggregation and can relieve coronary spasm.</p>Formule :C21H32O4Couleur et forme :SolidMasse moléculaire :348.4820-HEDE
CAS :20-HEDE (WIT 002) is a 20-hydroxyeicosatetraenoic acid (20-HETE) antagonist.Formule :C20H36O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.50Dioxamycin
CAS :<p>Dioxamycin exhibits activity against Gram-positive bacteria and inhibits Staphylococcus aureus 209P with a minimum inhibitory concentration (MIC) of 3.12 μg/mL. It also suppresses the proliferation of L1210, P388, IMC, LX-1, and SC-6 cells with IC50 values (μg/mL) of 2.7, 1.4, 6.0, 2.0, and 2.5, respectively.</p>Formule :C38H40O15Couleur et forme :SolidMasse moléculaire :736.715Oudenone
CAS :<p>Oudenone is an oxygen-containing heterocyclic antibiotic with mild antibacterial and antifungal properties. It also exhibits antihypertensive effects in rats with spontaneous hypertension.</p>Formule :C12H16O3Couleur et forme :SolidMasse moléculaire :208.254Enpp-1-IN-12
<p>ENPP1-IN-12 is a potent, oral ENPP1 inhibitor with a Ki of 41 nM and anti-tumor properties.</p>Formule :C17H19N5O3SCouleur et forme :SolidMasse moléculaire :373.43Difeterol
CAS :<p>Difeterol is a biochemical.</p>Formule :C25H29NO2Couleur et forme :SolidMasse moléculaire :375.50Henagliflozin
CAS :<p>Henagliflozin (SHR3824): an oral, selective SGLT2 inhibitor, weak on SGLT1.</p>Formule :C22H24ClFO7Couleur et forme :SolidMasse moléculaire :454.87PD-149163
CAS :<p>PD-149163: brain-penetrating, selective NTR1 agonist; shows pro-cognitive, anti-psychotic, anxiolytic effects.</p>Formule :C42H71N9O6Couleur et forme :SolidMasse moléculaire :798.07β-Carotene-15,15'-epoxide
CAS :<p>β-Carotene-15,15ʹ-epoxide acts as an XIAP antagonist with pro-apoptotic (Apoptosis) and anti-tumor properties, found in the leaves of Spondias mombin. In rat models of DMBA-induced breast cancer, it induces tumor cell apoptosis by binding to the BIR3 domain of the XIAP protein, thereby inhibiting its interaction with caspase-9. Additionally, β-carotene-15,15ʹ-epoxide significantly reduces BCL-2, COX-2, and TNF-α expression in tumor tissue, decreases MDA levels, enhances catalase activity, and modulates biochemical markers in serum such as LDH, ALP, and ALT, indicating its antioxidant, anti-inflammatory, and metabolic protective effects. This compound is useful for researching inflammation-related diseases and tumors such as breast cancer.</p>Formule :C40H56OCouleur et forme :SolidMasse moléculaire :552.872Acetoxycycloheximide
CAS :<p>Acetoxycycloheximide triggers TNF receptor 1, prompts apoptosis, and cytochrome c release by activating c-Jun N-terminal kinase.</p>Formule :C17H25NO6Couleur et forme :SolidMasse moléculaire :339.38MK-8318
CAS :<p>MK-8318 is an effective and selective antagonist of the CRTh2 receptor (Ki: 5.0 nM).</p>Formule :C27H26F4N2O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :534.5SORT1-IN-3
CAS :<p>SORT1-IN-3 (compound 5) is a SORT1 inhibitor characterized by its ability to permeate the blood-brain barrier.</p>Formule :C16H26ClNO3Couleur et forme :SolidMasse moléculaire :315.84PZ-3022
CAS :<p>PZ-3022 is an orally active, conformational PanK activator that counteracts C3-CoA inhibition. In a mouse model of propionic acidemia, it elevates hepatic CoASH and C2-CoA levels while reducing C3-CoA, making it useful for studying mitochondrial defects in propionic acidemia.</p>Formule :C20H21N5OCouleur et forme :SolidMasse moléculaire :347.41Enpp-1-IN-7
<p>Enpp-1-IN-7: potent enpp-1 inhibitor, broad specificity, potential in cancer/infectious disease research. (WO2021203772A1)</p>Formule :C18H19N7O4SCouleur et forme :SolidMasse moléculaire :429.45
