Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1381 produits trouvés pour "Signalisation du cytosquelette"
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NSC305787
CAS :<p>NSC305787 is an ezrin inhibitor with antitumor activity, inhibits ezrin phosphorylation caused by PKCΙ, and can be used in the study of pancreatic cancer.</p>Formule :C25H30Cl2N2ODegré de pureté :99.40%Couleur et forme :SolidMasse moléculaire :445.42Clathrin-IN-25
CAS :<p>Clathrin-IN-25 is the most effective clathrin terminal domain-amphiphysin inhibitor reported to date.</p>Formule :C19H13KNO5SCouleur et forme :SolidMasse moléculaire :406.47BGB659
CAS :<p>BGB659 is effective inhibitor of RAF.</p>Formule :C29H29F3N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.56HR22C16
CAS :<p>HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.</p>Formule :C23H23N3O3Couleur et forme :SolidMasse moléculaire :389.45CGP60474
CAS :<p>CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.</p>Formule :C18H18ClN5ODegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :355.82DAT1
CAS :<p>DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.</p>Formule :C17H15N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.38Shz 1
CAS :<p>Shz 1 is a cardiogenic agent that induces phenotypic differentiation and various cardiac-specific genes including sarcomeric tropomyosin.</p>Formule :C13H11BrN2O3SDegré de pureté :99.57% - 99.91%Couleur et forme :SolidMasse moléculaire :355.21GSK-3008348
CAS :<p>GSK-3008348 is an antagonist of integrin alpha(v)beta6.</p>Formule :C29H37N5O2Degré de pureté :99.547%Couleur et forme :SolidMasse moléculaire :487.64BNC105P
CAS :<p>BNC105P, a prodrug VDA, converts to BNC105, blocks tubulin polymerization, disrupts tumor vessels, and evades P-glycoprotein resistance.</p>Formule :C20H21O10PCouleur et forme :SolidMasse moléculaire :452.3485YM-01 Tosylate
CAS :<p>YM-01 Tosylate, a potent antitumor agent, selectively targets cancer cells and overcoming tamoxifen resistance.</p>Formule :C27H27N3O4S3Couleur et forme :SolidMasse moléculaire :553.72Displurigen
CAS :<p>Displurigen is an inhibitor of ATPase activity of HSP70.</p>Formule :C15H10O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :286.3NSC47924
CAS :<p>NSC47924 is a laminin receptor (LR) inhibitor.</p>Formule :C18H17NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :279.33ML-243
CAS :<p>inhibitor of cancer stem cells</p>Formule :C14H16N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :260.35Ro 43-5054
CAS :<p>Ro 43-5054 is a small molecular, noncyclic peptidomimetic inhibitor.</p>Formule :C24H27N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :497.5AKT-IN-9
CAS :<p>AKT-IN-9, a potent AKT inhibitor, may aid breast/prostate cancer studies. See WO2021185238A1.</p>Formule :C24H29ClN6OCouleur et forme :SolidMasse moléculaire :452.98D011-2120
CAS :<p>D011-2120: Antiviral that blocks microtubule growth, disrupts Golgi, and hinders viral egress.</p>Formule :C17H15NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :281.31JG-48
CAS :<p>JG-48 is an inhibitor of Hsp70. JG-48 suppresses phosphorylated and total Tau in cells, endogenous Tau in neuroblastoma cells.</p>Formule :C20H16F3N3OS2Couleur et forme :SolidMasse moléculaire :435.49Mps-BAY2b
CAS :<p>Mps-BAY2b is a novel MPS1 inhibitor.</p>Formule :C20H23N5OCouleur et forme :SolidMasse moléculaire :349.43PU24FCl
CAS :<p>PU24FCl is a specific inhibitor of tumor Hsp90.</p>Formule :C20H21ClFN5O3Couleur et forme :SolidMasse moléculaire :433.86LDN-193665
CAS :LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.Formule :C15H11FN4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :314.34BOP sodium
CAS :<p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>Formule :C25H29N3NaO7SCouleur et forme :SolidMasse moléculaire :538.57Mivobulin
CAS :<p>Mivobulin is an inhibitor of tubulin .</p>Formule :C17H19N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.37Hydromethylthionine HBr
CAS :<p>Hydromethylthionine (LMTM/Leucomethylene Blue) inhibits tau in Alzheimer's/frontotemporal dementia and improves brain function.</p>Formule :C16H21Br2N3SCouleur et forme :SolidMasse moléculaire :447.233ZW4864 free base
CAS :<p>ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor.</p>Formule :C33H42N6O3Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :570.72Diazobenzenesulfonic acid
CAS :<p>Diazobenzenesulfonic acid, white/red crystal, inhibits myosin ATPase 13 as an allosteric desensitizer.</p>Formule :C6H5N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :185.18Box5
CAS :<p>Box5 blocks Wnt5a, reducing Ca2+ release and cell migration; promising for melanoma studies.</p>Formule :C30H50N6O13S2Couleur et forme :SolidMasse moléculaire :766.88CCT036477
CAS :<p>CCT036477 selectively inhibits Wnt/β-catenin signaling, reducing TCF/LEF transcriptional activity.</p>Formule :C21H18ClN3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :347.84Acodazole hydrochloride
CAS :<p>Acodazole hydrochloride: synthetic imidazoquinoline with antineoplastic activity; disrupts DNA replication by intercalation.</p>Formule :C20H20ClN5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :381.86Tubulin polymerization-IN-37
CAS :<p>Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.</p>Formule :C19H20N2O4Couleur et forme :SolidMasse moléculaire :340.37αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
<p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>Formule :C28H35F3N6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :672.67Cevipabulin
CAS :<p>Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell</p>Formule :C18H18ClF5N6ODegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :464.82Anticancer agent 60
CAS :<p>Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.</p>Formule :C27H33N5O4SCouleur et forme :SolidMasse moléculaire :523.65ABH Hydrochloride
CAS :<p>ABH Hydrochloride is an arginase inhibitor, it enhances both male and female sexual arousal responses.</p>Formule :C6H15BClNO4Couleur et forme :SolidMasse moléculaire :211.45Malonganenone A
CAS :<p>Malonganenone A is a selective plasmodial Hsp70s modulator. It also has antimalarial activity.</p>Formule :C26H38N4O2Couleur et forme :SolidMasse moléculaire :438.61BMS-587101
CAS :<p>BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.</p>Formule :C26H20Cl2N4O4SCouleur et forme :SolidMasse moléculaire :555.43BMS-358233
CAS :<p>BMS-358233 is an effective LCK inhibitor with excellent cell activity against T cell proliferation.</p>Formule :C25H25ClN6O2SCouleur et forme :SolidMasse moléculaire :509.02Acodazole
CAS :<p>Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias.</p>Formule :C20H19N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :345.4L 703014
CAS :<p>L 703014 is an antagonist of the fibrinogen receptor.</p>Formule :C24H34N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :442.55TCS 2314
CAS :<p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>Formule :C28H34N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :522.59KIF18A-IN-3
CAS :<p>KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.</p>Formule :C28H38N4O5S2Degré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :574.76Hsp90-IN-17
CAS :<p>Hsp90-IN-17 (Example 5) is an inhibitor of HSP90, applicable in researching proliferative diseases, including cancer and neurodegenerative conditions.</p>Formule :C21H20N4O7Couleur et forme :SolidMasse moléculaire :440.41β-glycosidase-IN-1
CAS :<p>β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.</p>Formule :C13H23NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :273.33O-GlcNAcase-IN-4
CAS :<p>O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.</p>Formule :C16H22FN5O3SCouleur et forme :SolidMasse moléculaire :383.44OXi8007
CAS :<p>OXi8007, a water-soluble prodrug for OXi8006, disrupts vasculature and exhibits strong cytotoxicity against DU-145 cancer cells.</p>Formule :C26H24NNa2O10PCouleur et forme :SolidMasse moléculaire :587.428Tubulin inhibitor 7
CAS :<p>Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (</p>Formule :C21H14N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :358.35Tubulin polymerization-IN-7
CAS :<p>Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.</p>Formule :C28H24N4O6SCouleur et forme :SolidMasse moléculaire :544.58K-80003
CAS :<p>K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.</p>Formule :C22H21FO2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :336.4PF-2771
CAS :<p>PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.</p>Formule :C29H36ClN5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :554.08NC043
CAS :<p>NC043 is an inhibitor of Wnt/β-catenin signaling, it forms a covalent bond with the Cys-516 residue of CARF.</p>Formule :C20H26O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :330.42PP2A Cancerous-IN-1
CAS :<p>PP2A Cancerous-IN-1 is a potent inhibitor of CIP2A (Cancerous inhibitor of PP2A) and p-Akt that exhibits potent anti-proliferative effects.</p>Formule :C30H24N4O3Couleur et forme :SolidMasse moléculaire :488.54PU3
CAS :<p>PU3 is an inhibitor of Hsp90.</p>Formule :C19H25N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :371.43PD-173956
CAS :<p>PD-173956 is an inhibitor of the Src family tyrosine kinases.</p>Formule :C20H13Cl2FN4OCouleur et forme :SolidMasse moléculaire :415.25Aha1/Hsp90-IN-1
CAS :<p>Aha1/Hsp90-IN-1 (Compound 17) inhibits Aha1/Hsp90, preventing tau aggregation; IC50 = 3.32 μM.</p>Formule :C22H17F3N4O2Couleur et forme :SolidMasse moléculaire :426.39OSIP-486823
CAS :<p>OSIP-486823（CP248） is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.</p>Formule :C29H28FNO4Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :473.54KIF18A-IN-4
CAS :<p>KIF18A-IN-4: Non-competitive KIF18A inhibitor, IC50 6.16 μM, targets mitotic kinesins/kinases, anti-tumor.</p>Formule :C22H27N3O3SCouleur et forme :SolidMasse moléculaire :413.53PF-06651481-00
CAS :<p>PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.</p>Formule :C26H29Cl2N5O3Degré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :530.45NVS-PAK1-C
CAS :<p>NVS-PAK1-1: potent PAK1 inhibitor, IC50 5 nM (dephosphorylated), 6 nM (phosphorylated); ATP-competitive; weaker on PAK2 (IC50 270 nM, 720 nM).</p>Formule :C22H23ClF3N5OCouleur et forme :SoildMasse moléculaire :465.9EC 144
CAS :<p>EC 144, a second-generation selective inhibitor of Hsp90 , inhibits tumor growth for Hsp90α and degradation of Her-2 in MCF-7 cells.</p>Formule :C21H24ClN5O2Couleur et forme :SolidMasse moléculaire :413.9PS315
CAS :<p>PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.</p>Formule :C23H19ClO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :362.85Zaurategrast ethyl ester
CAS :<p>Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.</p>Formule :C28H29BrN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :549.46Tubulin inhibitor 31
<p>Tubulin inhibitor 31: potent with 4 µM IC50, anti-proliferative, inhibits HUVEC migration.</p>Formule :C22H19NO2Couleur et forme :SolidMasse moléculaire :329.39CLT-28643
CAS :<p>CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.</p>Formule :C19H17N3O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :351.36BCR-ABL-IN-1
CAS :<p>BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the research of chronic myelogenous leukemia.</p>Formule :C23H21F4N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.44GF 15
CAS :<p>GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.</p>Formule :C23H21ClO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.86CHPG
CAS :<p>CHPG is a selective mGluR5 agonist protects against traumatic brain injury.activates the ERK and Akt pathways, It also alleviates LPS-induced inflammation.</p>Formule :C8H8ClNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :201.61Microtubule inhibitor 6
CAS :<p>Compound 17o inhibits microtubules, toxic to NCI-H460, BxPC-3, HT-29 cells (IC50: 14.0, 6.6, 7.0 nM), blocks polymerization.</p>Formule :C24H19FN2O5Couleur et forme :SolidMasse moléculaire :434.42NSC-668036
CAS :<p>NSC-668036 is an inhibitor of Dishevelled (Dvl) protein, a key protein in wnt signaling.</p>Formule :C21H36N2O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.52NAMI-A
CAS :<p>NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.</p>Formule :C8H15Cl4N4ORuSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.18Tau-aggregation-IN-1
CAS :<p>Tau-aggregation-IN-1 is a dopamine D2 and D3 receptor agonist and an inhibitor of tau441 protein aggregation (IC50: 21 μM).</p>Formule :C28H37N5O2SCouleur et forme :SolidMasse moléculaire :507.69Tubulin polymerization-IN-29
CAS :<p>Tubulin polymerization-IN-29 inhibits microtubule assembly, has anti-proliferative properties, and arrests HeLa cells at G2/M.</p>Formule :C25H20FNO6Couleur et forme :SolidMasse moléculaire :449.43AK963
CAS :<p>AK963 (40708899) is a powerful PAK1 inhibitor reducing gastric cancer cell growth via the PAK1-NFκB-CyclinB1 pathway.</p>Formule :C16H18N2OCouleur et forme :SolidMasse moléculaire :254.33Valategrast hydrochloride
CAS :<p>Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.</p>Formule :C30H33Cl4N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :641.41EMD534085
CAS :<p>EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).</p>Formule :C25H31F3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :476.53(R)-TTBK1-IN-1
CAS :<p>(R)-TTBK1-IN-1: potent, selective brain-penetrant TTBK1 inhibitor, studies Alzheimer’s & tauopathies.</p>Formule :C18H19N5O2Couleur et forme :SolidMasse moléculaire :337.38BCR-ABL-IN-6
CAS :<p>BCR-ABL-IN-6, an imatinib derivative, inhibits Bcr-AblWT (4.6 nM IC50) and T315I (277 nM), for chronic myeloid leukemia study.</p>Formule :C27H22F3N5O2Couleur et forme :SolidMasse moléculaire :505.49SR31527
CAS :<p>SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.</p>Formule :C15H14ClN3OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.81Tubulin polymerization-IN-16
CAS :<p>Compound 5g is a potent tubulin aggregation inhibitor, disrupting microtubules and causing G2/M arrest in SGC-7901 cells.</p>Formule :C24H27N5O5Couleur et forme :SolidMasse moléculaire :465.5Syntelin
CAS :<p>Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.</p>Formule :C21H20N6O2S3Couleur et forme :SolidMasse moléculaire :484.62LS-104
CAS :<p>LS-104 is a JAK2 inhibitor.</p>Formule :C19H16N2O3Couleur et forme :SolidMasse moléculaire :320.34Tubulin polymerization-IN-39
<p>Tubulin-IN-39 inhibits polymerization (IC50: 4.9 μM), blocks colchicine site, stops cancer growth.</p>Formule :C21H21N5O5Couleur et forme :SolidMasse moléculaire :423.42Tubulin polymerization-IN-25
CAS :<p>Tubulin polymerization-IN-25 inhibits tubulin (IC50: 1.11 μM) & FTase (IC50: 0.39 μM), and is cytotoxic to cancer cells, halting growth.</p>Formule :C24H18N2O3SCouleur et forme :SolidMasse moléculaire :414.48AKT-IN-8
CAS :<p>AKT-IN-8 is a potent inhibitor of AKT, acting on AKT1 (IC50: 4.46 nM), AKT2 (IC50: 2.44 nM) and AKT3 (IC50: 9.47 nM).</p>Formule :C22H25ClN6O3Couleur et forme :SolidMasse moléculaire :456.93AKT-IN-5
CAS :<p>AKT-IN-5, an Akt inhibitor, targets Akt1/Akt2 with IC50s: 450/400 nM.</p>Formule :C23H20N4O2Couleur et forme :SolidMasse moléculaire :384.43Zalunfiban
CAS :<p>RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.</p>Formule :C16H18N8O2SCouleur et forme :SolidMasse moléculaire :386.43Zarilamide
CAS :<p>Zarilamide disrupts microtubules, inhibiting mitosis in Phytophthora capsici zoospore cysts.</p>Formule :C11H11ClN2O2Couleur et forme :SolidMasse moléculaire :238.67Integrin-IN-2
CAS :<p>Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.</p>Formule :C27H30N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.55CCT251236
CAS :<p>CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen.</p>Formule :C32H32N4O5Degré de pureté :98.82% - 99.89%Couleur et forme :SolidMasse moléculaire :552.62Tubulin polymerization-IN-36
CAS :<p>Tubulin polymerization-IN-36, a cancer research agent for lymphomas, inhibits tubulin at the colchicine site with IC50 of 2.8 µM.</p>Formule :C18H18N2O3Couleur et forme :SolidMasse moléculaire :310.35Neuroinflammatory-IN-3
CAS :<p>Neuroinflammatory-IN-3 is a potent tubulin inhibitor with anti-neuroinflammatory and antitumor properties.</p>Formule :C19H19ClO3Couleur et forme :SolidMasse moléculaire :330.81Sibrafiban
CAS :<p>Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.</p>Formule :C20H28N4O6Couleur et forme :SolidMasse moléculaire :420.46Tubulin polymerization-IN-20
CAS :<p>Tubulin aggregation-IN-20, a potent inhibitor, may be studied for breast and drug-resistant colon cancers.</p>Formule :C25H24FNO5Couleur et forme :SolidMasse moléculaire :437.46Tubulin polymerization-IN-42
CAS :<p>Tubulin polymerization-IN-42 (compound 10j), an indole-substituted furanone, inhibits tubulin polymerization and exhibits anti-cancer properties [1].</p>Formule :C22H21NO5Couleur et forme :SolidMasse moléculaire :379.41Tubulin/MMP-IN-1
<p>Tubulin/MMP-IN-1 inhibits tubulin, MMP, and cancer cell growth; disrupts cell cycles and induces apoptosis.</p>Formule :C38H44NO9PCouleur et forme :SolidMasse moléculaire :689.73Clathrin-IN-2
CAS :<p>Clathrin-IN-2: CME inhibitor, IC50 - 2.3μM; also blocks dyn I GTPase, IC50 - 7.7μM.</p>Formule :C17H18Br2N2OCouleur et forme :SolidMasse moléculaire :426.15HSP90-IN-20
CAS :<p>HSP90-IN-20, a potent inhibitor of HSP90, exhibits an IC50 of ≤10 μM, indicating its potential application in cancer research.</p>Formule :C26H32N4O4Couleur et forme :SolidMasse moléculaire :464.56Tubulin polymerization-IN-27
CAS :<p>Compound 5j inhibits tubulin polymerization, arrests cell cycle at G2/M phase, and induces apoptosis.</p>Formule :C22H20N2O2Couleur et forme :SolidMasse moléculaire :344.41YM-1
CAS :<p>YM-1, a stable MKT-077 analog, inhibits Hsp70 orally, kills HeLa cells, and boosts p53 and p21 proteins.</p>Formule :C20H20ClN3OS2Couleur et forme :SolidMasse moléculaire :417.98Tubulin inhibitor 12
CAS :<p>New tubulin inhibitor 12 (Hit 9); potent anti-cancer agent; IC50=25.3 μM; strong anti-tumor effect.</p>Formule :C24H20N2OCouleur et forme :SolidMasse moléculaire :352.43BCR-ABL1-IN-1
CAS :<p>BCR-ABL1-IN-1: potent, orally active ABL kinase inhibitor with high specificity, promising for CNS research.</p>Formule :C18H12F3N3O2Couleur et forme :SolidMasse moléculaire :359.3Drp1-IN-1
CAS :<p>Drp1-IN-1 (comp A-7) is a Drp1 protein inhibitor (IC50: 0.91 μM).</p>Formule :C22H24N8OSCouleur et forme :SolidMasse moléculaire :448.54
