Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1382 produits trouvés pour "Signalisation du cytosquelette"
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Tubulin inhibitor 12
CAS :<p>New tubulin inhibitor 12 (Hit 9); potent anti-cancer agent; IC50=25.3 μM; strong anti-tumor effect.</p>Formule :C24H20N2OCouleur et forme :SolidMasse moléculaire :352.43BCR-ABL1-IN-1
CAS :<p>BCR-ABL1-IN-1: potent, orally active ABL kinase inhibitor with high specificity, promising for CNS research.</p>Formule :C18H12F3N3O2Couleur et forme :SolidMasse moléculaire :359.3KY-04031
CAS :<p>KY-04031 is an inhibitor of p21-activated kinase 4.</p>Formule :C21H20N8OCouleur et forme :SolidMasse moléculaire :400.44AFG210
CAS :<p>AFG210 is a novel first-generation “type II” FLT3 inhibitor.</p>Formule :C19H14F3N3O2Couleur et forme :SolidMasse moléculaire :373.33BCR-ABL-IN-5
CAS :<p>BCR-ABL-IN-5: Bcr-Abl kinase inhibitor, IC50: Bcr-AblWT 0.014 μM, Bcr-AblT315I 0.45 μM; anti-leukemia cell growth.</p>Formule :C25H21Cl2N5O2Couleur et forme :SolidMasse moléculaire :494.37Iso-Fludelone
CAS :<p>Iso-Fludelone: a stable, soluble, potent, 3rd-gen epothilone B inhibiting cell division and inducing apoptosis, with low toxicity.</p>Formule :C27H36F3NO6Couleur et forme :SolidMasse moléculaire :527.5710-DEBC hydrochloride
CAS :<p>10-DEBC hydrochloride, a selective Akt inhibitor demonstrating an IC50 value of 1.28 μM, is identified as a novel anti-tuberculosis compound [1] [2].</p>Formule :C20H26Cl2N2OCouleur et forme :SolidMasse moléculaire :381.34DRP1i27
CAS :<p>DRP1i27 inhibits human Drp1 at GTPase site, prevents mitochondrial fission, and shields cells from ischemia-reperfusion damage.</p>Formule :C20H26N6OCouleur et forme :SolidMasse moléculaire :366.46KY-04045
CAS :<p>KY-04045 is a PAK4 inhibitor.</p>Formule :C13H14BrN5Couleur et forme :SolidMasse moléculaire :320.19NAMI-A
CAS :<p>NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.</p>Formule :C8H15Cl4N4ORuSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.18SSTC3
CAS :<p>SSTC3 is a casein kinase 1α (CK1α) activator with potential antitumor activity that inhibits WNT signaling.</p>Formule :C23H17F3N4O3S2Degré de pureté :98.65% - 99.94%Couleur et forme :SolidMasse moléculaire :518.53CHMFL-ABL-053
CAS :<p>CHMFL-ABL-053: potent, selective BCR-ABL/SRC/p38 inhibitor (IC50: 70/90/62 nM). Orally available, potential CML drug.</p>Formule :C28H26F3N7O2Couleur et forme :SolidMasse moléculaire :549.55BuChE-IN-5
CAS :<p>"BuChE-IN-5 is a potent inhibitor with an IC50 of 1.94 μM and shows promise for Alzheimer's research."</p>Formule :C25H35N3Couleur et forme :SolidMasse moléculaire :377.57Microtubule inhibitor 5
CAS :<p>Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.</p>Formule :C22H15FN2O4Couleur et forme :SolidMasse moléculaire :390.36AJH-836
CAS :<p>AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation of</p>Formule :C22H38O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :382.53Tubulin inhibitor 27
CAS :<p>DYT-1 Tubulin inhibitor 27, IC50: 25.6 μM, hinders tubulin polymerization, displays anti-angiogenic and antitumor effects.</p>Formule :C21H19NO4Couleur et forme :SolidMasse moléculaire :349.38Tubulin polymerization-IN-10
CAS :<p>Tubulin polymerization-IN-10 inhibits tubulin polymerization with 4.25 μM IC50 and has anti-tumor properties.</p>Formule :C18H21NO6SCouleur et forme :SolidMasse moléculaire :379.43HSP90-IN-22
CAS :<p>HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor exhibiting antiproliferative activity, with IC50 values of 3.65 μM in MCF7 breast cancer cells and 2.71 μM in</p>Formule :C25H30N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.53YM-1
CAS :<p>YM-1, a stable MKT-077 analog, inhibits Hsp70 orally, kills HeLa cells, and boosts p53 and p21 proteins.</p>Formule :C20H20ClN3OS2Couleur et forme :SolidMasse moléculaire :417.98Sibrafiban
CAS :<p>Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.</p>Formule :C20H28N4O6Couleur et forme :SolidMasse moléculaire :420.46Neuroinflammatory-IN-3
CAS :<p>Neuroinflammatory-IN-3 is a potent tubulin inhibitor with anti-neuroinflammatory and antitumor properties.</p>Formule :C19H19ClO3Couleur et forme :SolidMasse moléculaire :330.81Tubulin polymerization-IN-36
CAS :<p>Tubulin polymerization-IN-36, a cancer research agent for lymphomas, inhibits tubulin at the colchicine site with IC50 of 2.8 µM.</p>Formule :C18H18N2O3Couleur et forme :SolidMasse moléculaire :310.35Tubulin polymerization-IN-16
CAS :<p>Compound 5g is a potent tubulin aggregation inhibitor, disrupting microtubules and causing G2/M arrest in SGC-7901 cells.</p>Formule :C24H27N5O5Couleur et forme :SolidMasse moléculaire :465.5BCR-ABL-IN-6
CAS :<p>BCR-ABL-IN-6, an imatinib derivative, inhibits Bcr-AblWT (4.6 nM IC50) and T315I (277 nM), for chronic myeloid leukemia study.</p>Formule :C27H22F3N5O2Couleur et forme :SolidMasse moléculaire :505.49Retaspimycin
CAS :<p>Retaspimycin is a potent and water-soluble Hsp90 inhibitor(EC50s of 119 nM for both Hsp90 and Grp9).</p>Formule :C31H45N3O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :587.7Tubulin polymerization-IN-15
CAS :<p>Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].</p>Formule :C18H17N3O4Couleur et forme :SolidMasse moléculaire :339.35Tubulin inhibitor 18
CAS :<p>"Tubulin inhibitor 18 (5j), a potent chalcone, uniquely structured for cancer research."</p>Formule :C22H26O5Couleur et forme :SolidMasse moléculaire :370.44Tubulin polymerization-IN-18
CAS :<p>Tubulin aggregation-IN-18 (compound 3) is a potent tubulin aggregation inhibitor with potential for breast cancer and drug-resistant colon cancer studies.</p>Formule :C25H25NO6Couleur et forme :SolidMasse moléculaire :435.47GNF-1331
CAS :<p>GNF-1331: potent, selective oral porcupine inhibitor; IC50=12 nM; targets aberrant Wnt signaling in cancers.</p>Formule :C20H20N6O2S2Couleur et forme :SolidMasse moléculaire :440.54Synstab A
CAS :<p>Synstab A is a microtubule stabilizer.</p>Formule :C15H13BrCl3N3O3SCouleur et forme :SolidMasse moléculaire :501.61KUNB31
CAS :<p>KUNB31 is a potent and selective inhibitor of Hsp90β.</p>Formule :C19H18N2O3Couleur et forme :SolidMasse moléculaire :322.36Microtubule inhibitor 7
CAS :<p>Compounds 17o and 17p have IC50s of 14.0 nM and 2.9 nM respectively, in NCI-H460 cancer cells, showing potent activity.</p>Formule :C25H19FN2O5Couleur et forme :SolidMasse moléculaire :446.43(S)-Dolaphenine hydrochloride
CAS :<p>(S)-Dolaphenine hydrochloride is a useful componet of compound synthesis.</p>Formule :C11H13ClN2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :240.75Dihydrocytochalasin B
CAS :<p>Dihydrocytochalasin B (H2CB) is a cell division inhibitor that inhibits cytokinesis and alters cell morphology.</p>Formule :C29H39NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :481.62MK-0668
CAS :<p>MK-0668 is a very potent and orally active very late antigen-4 antagonist.</p>Formule :C31H30Cl2N6O6SCouleur et forme :SolidMasse moléculaire :685.58Tau tracer 1
CAS :<p>Tau tracer 1 is a radiopharmaceutical for imaging Tau aggregates linked to neurodegenerative disease diagnosis.</p>Formule :C34H23N5O2Couleur et forme :SolidMasse moléculaire :533.591Deox B 7,4
CAS :<p>Deox B 7,4 is a reversible microtubule inhibitor that acts by increasing lysosomal V-ATPase activity and lysosome acidity.</p>Formule :C18H18O5Couleur et forme :SolidMasse moléculaire :314.33SW02
CAS :<p>SW02 is a potent ATPase activator of Hsp70 (EC50: 150 μM). SW02 is able to accumulate total tau and phosphorylated tau (pTau).</p>Formule :C19H23BrN2O5Couleur et forme :SolidMasse moléculaire :439.3Tubulin polymerization-IN-30
CAS :<p>Compound 6e inhibits tubulin polymerization, disrupts microtubules, halts G2/M phase, and targets HeLa, SGC-7901, A549 with low IC50.</p>Formule :C22H25N5O3Couleur et forme :SolidMasse moléculaire :407.47Tubulin inhibitor 29
CAS :<p>Compound 3c, a tubulin inhibitor, blocks assembly at colchicine site with IC50 of 1.2 μM; anti-proliferative IC50 7.5 μM in MCF-7 cells.</p>Formule :C12H8F2O2S2Couleur et forme :SolidMasse moléculaire :286.32Microtubule inhibitor 6
CAS :<p>Compound 17o inhibits microtubules, toxic to NCI-H460, BxPC-3, HT-29 cells (IC50: 14.0, 6.6, 7.0 nM), blocks polymerization.</p>Formule :C24H19FN2O5Couleur et forme :SolidMasse moléculaire :434.42Tubulin inhibitor 31
<p>Tubulin inhibitor 31: potent with 4 µM IC50, anti-proliferative, inhibits HUVEC migration.</p>Formule :C22H19NO2Couleur et forme :SolidMasse moléculaire :329.39BCR-ABL-IN-1
CAS :<p>BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the research of chronic myelogenous leukemia.</p>Formule :C23H21F4N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.44PD-173956
CAS :<p>PD-173956 is an inhibitor of the Src family tyrosine kinases.</p>Formule :C20H13Cl2FN4OCouleur et forme :SolidMasse moléculaire :415.25Tubulin polymerization-IN-7
CAS :<p>Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.</p>Formule :C28H24N4O6SCouleur et forme :SolidMasse moléculaire :544.58PF-06651481-00
CAS :<p>PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.</p>Formule :C26H29Cl2N5O3Degré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :530.45β-glycosidase-IN-1
CAS :<p>β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.</p>Formule :C13H23NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :273.33TCS 2314
CAS :<p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>Formule :C28H34N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :522.59Anticancer agent 60
CAS :<p>Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.</p>Formule :C27H33N5O4SCouleur et forme :SolidMasse moléculaire :523.65Cevipabulin
CAS :<p>Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell</p>Formule :C18H18ClF5N6ODegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :464.82Mps-BAY2b
CAS :<p>Mps-BAY2b is a novel MPS1 inhibitor.</p>Formule :C20H23N5OCouleur et forme :SolidMasse moléculaire :349.43Mps1-IN-4
CAS :<p>Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.</p>Formule :C26H31F3N6O2Couleur et forme :SolidMasse moléculaire :516.56AP 24149
CAS :<p>AP 24149, a potent dual inhibitor targeting Src and Abl, exhibits IC50 values of 9.1 nM for Src and 3.6 nM for Abl, respectively.</p>Formule :C23H24N5OPCouleur et forme :SolidMasse moléculaire :417.44SB26019
CAS :<p>SB26019: Potent anti-neuroinflammation; inhibits NF-κB via α-tubulin monomers preventing p65 translocation.</p>Formule :C24H20O4Couleur et forme :SolidMasse moléculaire :372.41YW1159
CAS :<p>YW1159 is an inhibitor of Wnt signaling.</p>Formule :C19H14FN5OCouleur et forme :SolidMasse moléculaire :347.35AMXI-5001
CAS :<p>AMXI-5001: potent oral parp1/2 inhibitor, blocks microtubules, strong anti-cancer effects, lower IC50s, and can shrink large tumors.</p>Formule :C25H20FN5O3Couleur et forme :SolidMasse moléculaire :457.46Tubulin polymerization-IN-21
CAS :<p>Tubulin polymerization-IN-21 disrupts microtubules, affects glucose metabolism, and has anticancer properties.</p>Formule :C30H29NO7Couleur et forme :SolidMasse moléculaire :515.55AM-9635
CAS :<p>AM-9635: Potent PI3Kδ inhibitor, cellular IC50 4.2 nM, reduces IgG/IgM, well-tolerated, affects cell growth/division.</p>Formule :C19H14F2N8Couleur et forme :SolidMasse moléculaire :392.36Clathrin-IN-2
CAS :<p>Clathrin-IN-2: CME inhibitor, IC50 - 2.3μM; also blocks dyn I GTPase, IC50 - 7.7μM.</p>Formule :C17H18Br2N2OCouleur et forme :SolidMasse moléculaire :426.15Tubulin inhibitor 20
CAS :<p>Tubulin inhibitor 20 (compound 1) shows the potential for the cancer research that is a potent tubulin inhibitor [1].</p>Formule :C19H18O4Couleur et forme :SolidMasse moléculaire :310.34BIIB028
CAS :<p>BIIB028: Hsp90 inhibitor, may degrade oncogenic proteins, potentially hindering tumor growth.</p>Formule :C19H21ClN5O5PCouleur et forme :SolidMasse moléculaire :465.83Tubulin inhibitor 26
CAS :<p>Compound 3c, a potent indazole-based tubulin inhibitor, halts G2/M phase and induces apoptosis in various cancers without weight loss in mice.</p>Formule :C17H19N3O3Couleur et forme :SolidMasse moléculaire :313.35O-GlcNAcase-IN-4
CAS :<p>O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.</p>Formule :C16H22FN5O3SCouleur et forme :SolidMasse moléculaire :383.44BMS-587101
CAS :<p>BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.</p>Formule :C26H20Cl2N4O4SCouleur et forme :SolidMasse moléculaire :555.43Tubulin polymerization-IN-37
CAS :<p>Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.</p>Formule :C19H20N2O4Couleur et forme :SolidMasse moléculaire :340.37BOP sodium
CAS :<p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>Formule :C25H29N3NaO7SCouleur et forme :SolidMasse moléculaire :538.57THK-5117
CAS :<p>THK-5117, a tau PET probe, has a high tau fibril affinity (Ki 10.5 nM) and binds well to AD brain aggregates.</p>Formule :C19H19FN2O2Couleur et forme :SolidMasse moléculaire :326.36Integrin modulator 1
CAS :<p>Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.</p>Formule :C13H14N2O4Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :262.26XVA143
CAS :<p>XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.</p>Formule :C25H21Cl2N3O8Couleur et forme :SolidMasse moléculaire :562.36Debio 0617B
CAS :<p>Debio 0617B inhibits kinases for AML stem cell treatment, targeting JAK, ABL, SRC, and STAT3-related tumours.</p>Formule :C28H23ClF3N7O2Couleur et forme :SolidMasse moléculaire :581.98Antitumor agent-68
CAS :<p>Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.</p>Formule :C17H11NO2Couleur et forme :SolidMasse moléculaire :261.27Antitumor agent-71
CAS :<p>Antitumor Agent-71 inhibits tubulin aggregation; IC50 of 3.98-15.70 μM against cancer cells.</p>Formule :C26H31N5O4SCouleur et forme :SolidMasse moléculaire :509.62BMS-358233
CAS :<p>BMS-358233 is an effective LCK inhibitor with excellent cell activity against T cell proliferation.</p>Formule :C25H25ClN6O2SCouleur et forme :SolidMasse moléculaire :509.02PU24FCl
CAS :<p>PU24FCl is a specific inhibitor of tumor Hsp90.</p>Formule :C20H21ClFN5O3Couleur et forme :SolidMasse moléculaire :433.86KIF18A-IN-4
CAS :<p>KIF18A-IN-4: Non-competitive KIF18A inhibitor, IC50 6.16 μM, targets mitotic kinesins/kinases, anti-tumor.</p>Formule :C22H27N3O3SCouleur et forme :SolidMasse moléculaire :413.53Sabeluzole
CAS :<p>Sabeluzole (R-58735) has antiepileptic and cognitive enhancing properties and may be used in the study of Alzheimer's disease.</p>Formule :C22H26FN3O2SDegré de pureté :98.51%Couleur et forme :SolidMasse moléculaire :415.52Valategrast hydrochloride
CAS :<p>Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.</p>Formule :C30H33Cl4N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :641.41αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
<p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>Formule :C28H35F3N6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :672.67K-80003
CAS :<p>K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.</p>Formule :C22H21FO2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :336.4PS315
CAS :<p>PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.</p>Formule :C23H19ClO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :362.85AKT-IN-2
CAS :<p>AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).</p>Formule :C25H34F3N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :505.58Balamapimod
CAS :<p>Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.</p>Formule :C30H32ClN7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :574.14GB1874
CAS :<p>GB1874 is an inhibitor of the Wnt pathway targeting β-catenin-TCF4 protein-protein interaction (PPI), affecting proliferation in Wnt-dependent CRC cells.</p>Formule :C24H27N3O2SCouleur et forme :SolidMasse moléculaire :421.56AMP-PCP
CAS :<p>AMP-PCP is an ATP analog and can bind to the Hsp90 N-terminal domain (Kd: 3.8 μM). AMP-PCP binding favors the formation of the active homodimer of Hsp90.</p>Formule :C11H18N5O12P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :505.21SR31527
CAS :<p>SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.</p>Formule :C15H14ClN3OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.81Eg5 Inhibitor V, trans-24
CAS :<p>Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.</p>Formule :C26H21N3O3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :423.46BBO-10203
CAS :<p>BBO-10203 is an oral small molecule that disrupts PI3Kα-Ras interaction, inhibits Akt signaling selectively, and targets KRAS-mutant tumors.</p>Formule :C34H30F2N6O3SDegré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :640.7ZINC194100678
CAS :<p>ZINC194100678 is an effective PAK1 inhibitor with IC50 of 8.37μM.</p>Formule :C10H13N5ODegré de pureté :98.3%Couleur et forme :SolidMasse moléculaire :219.24TC-Mps1-12
CAS :<p>TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .</p>Formule :C17H20N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.38KP-23172
CAS :<p>KP-23172 is a inhibitor of PI3-K/Akt pathway.</p>Formule :C10H4N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :224.18Tau-aggregation and neuroinflammation-IN-1
CAS :<p>Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.</p>Formule :C25H20N2O7Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :460.44BCR-ABL-IN-7
CAS :<p>BCR-ABL-IN-7 is an inhibitor of ABL kinase activity in WT and T315I mutants.BCR-ABL-IN-7 can be used in chronic myeloid leukemia (CML) research.</p>Formule :C19H16FN3O3SDegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :385.41CpCDPK1/TgCDPK1-IN-1
CAS :<p>CpCDPK1/TgCDPK1-IN-1 is a inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections.</p>Formule :C18H17N5Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :303.36AM-5308
CAS :<p>AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.</p>Formule :C26H35N5O5SDegré de pureté :98.06% - 99.58%Couleur et forme :SolidMasse moléculaire :529.65CGP60474
CAS :<p>CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.</p>Formule :C18H18ClN5ODegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :355.82Pentachloropseudilin
CAS :<p>Pentachloropseudilin inhibits Myosin-1 and speeds up TGF-β receptor turnover, suppressing TGF-β activity.</p>Formule :C10H4Cl5NODegré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :331.41Tyrphostin AG 568
CAS :<p>Tyrphostin AG 568 promotes Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity. It also induces K562 to differentiate.</p>Formule :C13H9N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :267.24DHNQ
CAS :<p>DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).</p>Formule :C18H14N2OCouleur et forme :SolidMasse moléculaire :274.32NSC305787
CAS :<p>NSC305787 is an ezrin inhibitor with antitumor activity, inhibits ezrin phosphorylation caused by PKCΙ, and can be used in the study of pancreatic cancer.</p>Formule :C25H30Cl2N2ODegré de pureté :99.40%Couleur et forme :SolidMasse moléculaire :445.42Clathrin-IN-25
CAS :<p>Clathrin-IN-25 is the most effective clathrin terminal domain-amphiphysin inhibitor reported to date.</p>Formule :C19H13KNO5SCouleur et forme :SolidMasse moléculaire :406.47
