Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1381 produits trouvés pour "Signalisation du cytosquelette"
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AMXI-5001 hydrochloride
<p>AMXI-5001 hydrochloride, an oral inhibitor of PARP1/2 and microtubules, shows greater potency and selective anti-cancer effects.</p>Formule :C25H21ClFN5O3Couleur et forme :SolidMasse moléculaire :493.92AS2521780
CAS :<p>AS2521780 is an inhibitor of PKCθ (IC50: 0.48 nM).</p>Formule :C30H41N7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :547.76L 734217
CAS :<p>L 734217 is an antagonist of the fibrinogen receptor.</p>Formule :C18H31N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :353.46NRX-2663
CAS :<p>NRX-2663 boosts β-catenin binding to E3 ligase SCFβ-TrCP (Kd: 54.8 nM, EC50: 22.9 nM).</p>Formule :C20H13F3N2O5Couleur et forme :SolidMasse moléculaire :418.32PROTAC α-synuclein degrader 6
CAS :<p>PROTACα-synuclein degrader 6 (compound T3) is a PROTAC degrader of α-synuclein and tau, with an EC50 of 1.57 μM and 4.09 μM, respectively. This compound plays a significant role in neurodegenerative disease (ND) research.</p>Formule :C37H39N5O9SMasse moléculaire :729.80ETB
CAS :<p>ETB is a potent inhibitor of Hsp60 chaperone activity. It can impede the chaperone function of both wild-type proteins and the C237A and C447A mutant proteins. ETB binds to Hsp60 at Cys442, and the C442A mutant demonstrates resistance to ETB inhibition.</p>Formule :C24H33NO6Masse moléculaire :431.52SPA0355
CAS :<p>SPA0355 is a thiourea derivative with antioxidant and anti-inflammatory properties. It inhibits RANKL (receptor activator of nuclear factor κB ligand)-induced osteoclastogenesis in primary bone marrow-derived macrophages and suppresses the activation of MAPKs, Akt, and NF-κB pathways. Furthermore, SPA0355 enhances osteoblast differentiation by increasing alkaline phosphatase activity and mineralized nodule formation. It protects ovariectomized mice from bone loss by stimulating osteoblast differentiation and inhibiting osteoclast resorption, making it a potential candidate for studying postmenopausal osteoporosis.</p>Formule :C22H21N3O2SCouleur et forme :SolidMasse moléculaire :391.486Hsp90-IN-38
CAS :<p>Hsp90-IN-38 (compound 20m) is an inhibitor of HSP90 (heat shock protein). It demonstrates a strong binding affinity to HSP90 with a Kd of 87 nM. The compound inhibits ATPase activity with an IC50 of 0.13 μM. Hsp90-IN-38 also shows inhibitory effects on HCT116, MCF-7, SKBr3, K562, and A549 cells with IC50 values of 0.187, 0.072, 0.105, 0.403, and 0.031 μM, respectively.</p>Formule :C28H35N3O5Couleur et forme :SolidMasse moléculaire :493.595Terpendole E
CAS :<p>Terpendole E is an atypical L5 site inhibitor.</p>Formule :C28H39NO3Couleur et forme :SolidMasse moléculaire :437.61AMG28
CAS :<p>AMG28 is an inhibitor of Tau tubulin kinase 1 (TTBK1) and TTBK2, with IC50 values of 805 nM and 988 nM, respectively. Additionally, AMG28 suppresses the phosphorylation of tau protein at the Ser422 site, with an IC50 of 1.85 μM.</p>Formule :C20H20N4OCouleur et forme :SolidMasse moléculaire :332.399Tubulin polymerization-IN-32
<p>Tubulin polymerization-IN-32: a cancer cell growth inhibitor used for research in cancers like lymphoma.</p>Formule :C29H30N2O7Couleur et forme :SolidMasse moléculaire :518.56Mps1-IN-8
CAS :<p>Mps1-IN-8, a Mps1 inhibitor, can be utilized in the study of various tumors [1].</p>Formule :C35H47N8O6PCouleur et forme :SolidMasse moléculaire :706.77Tubulin polymerization-IN-33
<p>Tubulin-IN-33, an oxazoloisoindole, hinders microtubule assembly; effective against NCI cancer cells.</p>Formule :C27H28N2O6Couleur et forme :SolidMasse moléculaire :476.52PP487
CAS :<p>PP487 is a dual tyrosine kinase/PI(3)K inhibitor, exhibiting IC50 values of 0.017 μM, 0.072 μM, 0.004 μM, 0.01 μM, 0.55 μM, 0.22 μM, and < 0.01 μM against DNA-PK, mTOR, Hck, Src, EGFR, EphB4, and PDGFR, respectively. It is applicable in cancer research [1].</p>Formule :C14H14BrN5OCouleur et forme :SolidMasse moléculaire :348.2Dictyostatin
CAS :<p>Dictyostatin: potent microtubule stabilizer & anticancer agent with antiproliferative effects; researched for tauopathies.</p>Formule :C32H52O6Couleur et forme :SolidMasse moléculaire :532.75Tubulin polymerization-IN-8
CAS :<p>Compound IIc inhibits tubulin polymerization, arrests cell cycle at G2/M in HCT116 cells, IC50 12.7 μM, potential for cancer research.</p>Formule :C21H24N4O4SCouleur et forme :SolidMasse moléculaire :428.5AKT-IN-10
CAS :<p>AKT-IN-10, a potent AKT inhibitor, has potential for breast and prostate cancer research, impacting cell growth and survival pathways.</p>Formule :C26H34ClN5O2Couleur et forme :SolidMasse moléculaire :484.03MT-134
<p>MT-134 is a SkMII -specific inhibitor and has excellent exposure in muscles.</p>Formule :C19H16N4O3Couleur et forme :SolidMasse moléculaire :348.36GSD-11
<p>GSD-11: Potent, selective anti-austerity agent; blocks Akt/mTOR pathway, hinders PANC-1 cell migration & colony growth. Promising for pancreatic cancer study.</p>Formule :C20H28O2Couleur et forme :SolidMasse moléculaire :300.44Tubulin polymerization-IN-63
CAS :<p>Tubulin polymerization-IN-63 (compound 6) is an inhibitor of tubulin polymerization. It exhibits an IC50 value of 0.29 μM against MES-SA cells, making it suitable for use in cancer research.</p>Formule :C20H24ClCuN5O2SCouleur et forme :SolidMasse moléculaire :497.5Epothilone E
CAS :<p>Epothilone E, a derivative of epothilone, functions by inhibiting microtubule protein activity, thereby halting cell division and exhibiting anti-tumor</p>Formule :C26H39NO7SCouleur et forme :SolidMasse moléculaire :509.66Kolavenic acid analog
CAS :<p>KAA, an anticancer compound, inhibits centrosome clustering and targets HSET+ yeast and cancer cells.</p>Formule :C25H38O4Couleur et forme :SolidMasse moléculaire :402.57FPDT
<p>FPDT combats glioblastoma by inhibiting the AKT pathway; IC50: >100 μM (astrocytes), 45-68 μM (GBM cells).</p>Formule :C16H12FNO2SCouleur et forme :SolidMasse moléculaire :301.34Tubulin inhibitor 22
<p>Compound 4c: Strong tubulin inhibitor with anti-cancer & anti-angiogenic effects; halts MGC-803 cells in G2/M, triggers Caspase-mediated apoptosis.</p>Formule :C20H17BrFNO4Couleur et forme :SolidMasse moléculaire :434.26G-9791
CAS :<p>G-9791 is an effective and selective inhibitor of group-I PAK.</p>Formule :C26H26ClFN6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :508.98Icafolin-methyl
CAS :<p>Icafolin-methyl is a plant-specific herbicide that acts as an inhibitor of tubulin polymerization. In plants, it metabolizes into the carboxylic acid icafolin, potentially inhibiting plant tubulin polymerization by binding to β-tubulin.</p>Formule :C18H18F2N2O5Couleur et forme :SolidMasse moléculaire :380.343Nrf2/HO-1 activator 2
<p>Compound 13m, a difluoro derivative, activates Nrf2/HO-1, showing neuroprotective and antioxidant effects, useful in PD research.</p>Formule :C20H16F2O5Couleur et forme :SolidMasse moléculaire :374.33EV206
CAS :<p>EV206 is an effective inhibitor of Hsp70, exhibiting antiproliferative properties. This compound induces cell apoptosis (apoptosis) and enhances the protein expression of cleaved PARP and caspase-3. Additionally, EV206 demonstrates antitumor activity.</p>Formule :C21H19N3OCouleur et forme :SolidMasse moléculaire :329.40HSP90α-IN-1
CAS :<p>HSP90α-IN-1 is an HSP90α inhibitor (IC50= 111 nM) that demonstrates anti-aging activity across various cellular senescence models. Belonging to the xanthine family, HSP90α-IN-1 is involved in research focused on combating age-related inflammation, senescence, and diseases (including cancer), and it may contribute to extending healthy lifespan.</p>Formule :C19H16N4O2Couleur et forme :SolidMasse moléculaire :332.356Dioleyl phosphatidylserine
CAS :<p>Dioleyl phosphatidylserine is a phospholipid that can activate PKC-γ (Protein Kinase C-gamma) when the Ca2+ concentration is below 0.5 μM, specifically at a concentration of 100 μM.</p>Formule :C42H78NO10PCouleur et forme :SolidMasse moléculaire :788.04FAK-IN-21
CAS :<p>FAK-IN-21 (compound 9) is a FAK inhibitor with an IC50 value of 37.52 nM. It inhibits cell growth and the phosphorylation of FAK, making it useful for research into diffuse gastric cancer.</p>Formule :C22H22F2N8O3SCouleur et forme :SolidMasse moléculaire :516.52Tubulin inhibitor 19
<p>Tubulin inhibitor 19 (9b), a potent indole chalcone, strongly blocks tubulin, valuable in cancer studies.</p>Formule :C21H23NO5Couleur et forme :SolidMasse moléculaire :369.41Fradafiban
CAS :<p>Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.</p>Formule :C20H21N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :367.40Monomethyl auristatin E intermediate-17
CAS :<p>MonomethylauristatinE intermediate-17 is an intermediate compound used in the synthesis of MonomethylauristatinE. MonomethylauristatinE (MMAE) functions as a microtubule/tubulin inhibitor with anticancer properties. It is widely utilized as the cytotoxic component in antibody-drug conjugates (ADCs).</p>Formule :C27H35NO7SMasse moléculaire :517.636-B345TTQ
CAS :<p>6-B345TTQ is an α4 integrin inhibitor that can impede the interaction between α4 and Leupaxin. This compound is applicable for studies focused on inflammation research.</p>Formule :C22H20BrNO4Couleur et forme :SolidMasse moléculaire :442.303β-Catenin modulator-8
CAS :<p>β-Catenin modulator-8 (Compound Ⅸa) is a specific β-catenin modulator for use in cancer research.</p>Formule :C17H20N2O2SDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :316.42Des-ethyl-carafiban
CAS :<p>Des-ethyl-carafiban (Compound 44) is an antagonist of the fibrinogen receptor, effectively inhibiting platelet aggregation induced by various agonists. It is useful for research in thrombotic diseases.</p>Formule :C22H23N5O5Couleur et forme :SolidMasse moléculaire :437.448Lisavanbulin
CAS :<p>Lisavanbulin (BAL-101553) is a prodrug of Avanbulin (BAL 27862), a microtubule-targeting agent. It exhibits antitumor activity, particularly effective against tumors with high expression of end-binding protein 1.</p>Formule :C26H29N9O3Couleur et forme :SolidMasse moléculaire :515.57Hsp90-IN-34
CAS :<p>Hsp90-IN-34 (compound HAM-1) is a chemical inhibitor that targets the Aha1-Hsp90 chaperone complex with high affinity (KDapp=23.5 µM). It modulates the ATPase activity of Hsp90 by affecting the interaction between Hsp90 and Aha1.</p>Formule :C22H14F2N6OCouleur et forme :SolidMasse moléculaire :416.38KU-32
CAS :<p>KU-32 is a novel and novobiocin-based Hsp90 inhibitor. It can protect against neuronal cell death.</p>Formule :C20H25NO8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :407.41EX05
CAS :<p>EX05, an effective KIF18A inhibitor, exhibits an IC50 of 8.2 nM and holds potential for cancer research applications.</p>Formule :C26H30F2N4O5SCouleur et forme :SolidMasse moléculaire :548.60AChE/GSK-3β-IN-1
CAS :<p>AChE/GSK-3β-IN-1 is a potent dual AChE/GSK-3β inhibitor that crosses the blood-brain barrier and acts on hAChE (IC50: 1.2 nM), hBChE (IC50: 149.8 nM) and hGSK-</p>Formule :C31H35N7O3SCouleur et forme :SolidMasse moléculaire :585.72AM-9022
CAS :<p>AM-9022 is a potent and selective KIF18A inhibitor, orally active and suitable for cancer research [1].</p>Formule :C27H36F2N6O4SCouleur et forme :SolidMasse moléculaire :578.67Zalunfiban dihydrochloride
<p>Zalunfiban (RUC-4) is a potent αIIbβ3 platelet antagonist, IC50 45 nM, used in myocardial infarction research.</p>Formule :C16H20Cl2N8O2SCouleur et forme :SolidMasse moléculaire :459.35α5β1 integrin agonist-1
CAS :<p>α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death.</p>Formule :C24H26FN5O9Couleur et forme :SolidMasse moléculaire :547.49HSP90-IN-9
<p>HSP90-IN-9: potent HSP90 inhibitor, dose-dependent fungicide, impedes biofilm/morphology with FLC, reverses FLC resistance.</p>Couleur et forme :SolidTyrosine kinase-IN-9
CAS :<p>Tyrosine kinase-IN-9 (Compound B) is an inhibitor of c-Abl. It is useful for studying neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease.</p>Formule :C20H14ClN3O3Couleur et forme :SolidMasse moléculaire :379.796MKLP2-IN-1
CAS :<p>MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 that demonstrates excellent oral bioactivity. In vitro, MKLP2-IN-1 inhibits the ATPase activity stimulated by recombinant MKLP2 microtubules and, in a mouse Calu-6 lung cancer model, it effectively suppresses tumor growth.</p>Formule :C23H19BrFN3O2Couleur et forme :SolidMasse moléculaire :468.318Antitumor agent-200
CAS :<p>Antitumor agent-200 (Compound 2g) is a microtubule synthesis inhibitor that binds to the colchicine site on tubulin, causing G2/M cell cycle arrest and inducing reactive oxygen species (ROS) production. It demonstrates significant inhibitory activity against P-glycoprotein (P-gp) overexpressing cell lines MCF7/ADR and KBV200, with resistance indices (DRI) of 0.83 and 0.58, respectively. In an MCF-7 xenograft model, Antitumor agent-200 (at 25 mg/kg, administered intraperitoneally) achieves a 57.2% tumor growth inhibition rate. This compound is applicable for research in the field of cancer therapy.</p>Formule :C19H21FN2O3SeCouleur et forme :SolidMasse moléculaire :423.34DDO-6691
CAS :<p>DDO-6691 is an inhibitor of heat shock protein 90 (HSP90). It exhibits antiproliferative effects against various tumor cells, with the highest sensitivity observed in HCT-116 colon cancer cells (IC50: 1.08 μM). DDO-6691 also demonstrates potent tumor growth inhibition in HCT-116 xenograft mouse models.</p>Formule :C22H17N3O2SCouleur et forme :SolidMasse moléculaire :387.45Tubulin polymerization-IN-35
<p>Tubulin-IN-35 inhibits oxazolylisoindole microtubule formation, targeting VL51 marginal zone lymphoma.</p>Formule :C31H35N3O5Couleur et forme :SolidMasse moléculaire :529.63Tubulin inhibitor 15
<p>Tubulin inhibitor 15 is a potent tubulin inhibitor with antiproliferative activity. Tubulin inhibitor 15 exhibits cytotoxicity in HepG2 cells [1].</p>Formule :C16H12FNO2Couleur et forme :SolidMasse moléculaire :269.27Ethaboxam
CAS :<p>Ethaboxam is a β-tubulin inhibitor and antifungal agent used against oomycete pathogens.</p>Formule :C14H16N4OS2Degré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :320.43AKT-IN-26
CAS :<p>AKT-IN-26 (Compound 453) is an AKT inhibitor that binds to the Pleckstrin Homology (PH) domain of AKT. It is useful for research related to cell proliferation and cancer involving the AKT pathway.</p>Formule :C21H17N5O4SCouleur et forme :SolidMasse moléculaire :435.456Tubulin inhibitor 49
CAS :<p>Tubulin inhibitor 49 (Compound 18) is an inhibitor of tubulin polymerization with an IC50 of 48 μM. It disrupts the microtubule network of cells, causing cell cycle arrest in the G2 phase, and exhibits cytotoxicity with an IC50 of 8.8 μM in HeLa cells.</p>Formule :C18H14F3N3OSCouleur et forme :SolidMasse moléculaire :377.383Onalespib lactate
CAS :<p>Onalespib lactate is a second-generation, potent and selective HSP90 Inhibitor with antitumor activity.</p>Formule :C27H37N3O6Couleur et forme :SolidMasse moléculaire :499.6Tasidotin hydrochloride
CAS :<p>Tasidotin hydrochloride, a dolastatin 15 analog, inhibits microtubule assembly and dynamics.</p>Formule :C32H59ClN6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :643.30TACC3 inhibitor 2
CAS :<p>TACC3 inhibitor 2 (Compound 13b) is a TACC3 inhibitor with an IC50 of 200 nM. It induces mitotic arrest, apoptosis (Apoptosis), and DNA damage. TACC3 inhibitor 2 is applicable for research in the field of cancer.</p>Formule :C20H22FN5O2Couleur et forme :SolidMasse moléculaire :383.419Wikstrol A
CAS :<p>Wikstrol A: antifungal, anti-mitotic, anti-HIV agent with various IC50/MDC values (67.8-131 µM) and deforms P. oryzae mycelia.</p>Formule :C30H22O10Couleur et forme :SolidMasse moléculaire :542.49Tubulin polymerization-IN-75
CAS :<p>Tubulin polymerization-IN-75 (Compound 6) is an inhibitor of tubulin polymerization, with an IC50 value of 30 μM. It effectively suppresses the proliferation of cancer cells Huh7 and 293T, demonstrating IC50 values of 14.3 μM and 13.8 μM, respectively.</p>Formule :C14H11NOCouleur et forme :SolidMasse moléculaire :209.243TTBK1/2-IN-3
CAS :<p>TTBK1/2-IN-3 (compound 10) is a potent inhibitor of Tau tubulin kinase 1 (TTBK1) and TTBK2, with IC50 values of 579 nM and 258 nM, respectively. TTBK1/2-IN-3 can reduce the expression of primary cilia on the surface of human induced pluripotent stem cells (iPSC).</p>Formule :C21H22N4OCouleur et forme :SolidMasse moléculaire :346.426Ack1 inhibitor 1
CAS :<p>Ack1 inhibitor 1 is a potent and selective orally active inhibitor of ACK1 kinase, with an IC50 value of 2.1 nM. It effectively inhibits the phosphorylation of ACK1 and the activation of downstream AKT, demonstrating anti-tumor activity [1].</p>Formule :C39H40F3N7O4Couleur et forme :SolidMasse moléculaire :727.77RMS-07
CAS :<p>RMS-07, a covalent MPS1/TTK inhibitor, has an IC50 of 13.1 nM, targeting a kinase hinge cysteine.</p>Formule :C35H40N8O2Couleur et forme :SolidMasse moléculaire :604.74Macbecin I
CAS :<p>Hsp90 inhibitor</p>Formule :C30H42N2O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :558.66Tubulin polymerization-IN-74
CAS :<p>Tubulin polymerization-IN-74 (compound 11) is an inhibitor of tubulin polymerization, with an IC50 value of 15 μM. It is applicable to cancer research.</p>Formule :C14H11NSCouleur et forme :SolidMasse moléculaire :225.309Tubulin polymerization-IN-34
<p>"Tubulin-IN-34 inhibits oxazolylisoindole microtubule assembly, selective for VL51 lymphoma."</p>Formule :C31H35N3O6Couleur et forme :SolidMasse moléculaire :545.63NRX-103094
CAS :<p>NRX-103094 boosts β-catenin binding to SCFβ-TrCP ligase with EC50 62 nM and Kd 0.6 nM.</p>Formule :C20H11Cl2F3N2O4SDegré de pureté :99.13%Couleur et forme :SolidMasse moléculaire :503.28NRX-252114
CAS :<p>NRX-252114 promotes mutant β-catenin degradation, binding it to E3 ligase SCFβ-TrCP (EC50: 6.5 nM; Kd: 0.4 nM).</p>Formule :C22H12Cl2F3N3O2SDegré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :510.32AKT Kinase Inhibitor
CAS :<p>AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity that selectively inhibits cell proliferation in a dose-dependent manner.Cost-effective and quality-assured.</p>Formule :C16H19N7O3Degré de pureté :97.83% - 99.13%Couleur et forme :SolidMasse moléculaire :357.37Ombrabulin
CAS :<p>Ombrabulin is a derivative of CA-4 phosphate. It is known to show antivascular effects through selective disruption of the tubulin cytoskeleton of endothelial cells.</p>Formule :C21H26N2O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :402.44Tau tracer 2
CAS :<p>Tau tracer 2 (Pl-2620) is a specific imaging agent designed to detect and visualize Tau protein aggregates, primarily used for diagnosing neurodegenerative diseases [1].</p>Formule :C15H9FN4Couleur et forme :SolidMasse moléculaire :264.26324-Methylenecycloartanyl ferulate
CAS :<p>24-Methylenecycloartanyl ferulate, a compound belonging to the γ-oryzanol family, demonstrates the ability to enhance parvin-beta expression within human breast cancer cells. Furthermore, it exhibits potential as an ATP-competitive Akt1 inhibitor, with an EC 50 value of 33.3 μM.</p>Formule :C41H60O4Couleur et forme :SolidMasse moléculaire :616.927ZW4864
CAS :<p>ZW4864 is a selective inhibitor of the β-catenin/B-Cell Lymphoma 9 protein (β-catenin/BCL9 PPI) interaction, demonstrating oral activity. It inhibits β-catenin/BCL9 PPI with a K_i value of 0.76 μM and an IC_50 value of 0.87 μM.</p>Formule :C33H43ClN6O3Couleur et forme :SolidMasse moléculaire :607.2Cercosporin
CAS :<p>Cercosporin, produced by the plant pathogen Cercospora kikuchii and the elsinochromes, is a potent photosensitizer with a short activation wavelength. Cercosporin contains perylene quinone structural features essential for PKC activity (IC50: 0.6-1.3 μM).</p>Formule :C29H26O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :534.5120-HETE
CAS :<p>20-HETE is a CYP450 product, vasoconstrictor, modulates K+ channels, affects NADPH, ROS, NF-κB, NO synthase, and cell apoptosis/proliferation.</p>Formule :C20H32O3Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :320.47Sevasemten
CAS :<p>Sevasemten is an allosteric inhibitor that targets skeletal muscle myosin. It displays selectivity in its inhibition, demonstrated by IC50 values of ≤10 μM for skeletal muscle myosin and >100 μM for cardiac myosin, respectively.</p>Formule :C16H11F4N5O2Couleur et forme :SolidMasse moléculaire :381.28PF-03814735
CAS :<p>PF-03814735 is a novel, potent and reversible inhibitor of Aurora A/B with IC50of 0.8 nM/5 nM, is less potent to Flt3, FAK, TrkA, and minimally active to Met and FGFR1. Phase 1.</p>Formule :C23H25F3N6O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :474.48Cevipabulin fumarate
CAS :<p>Cevipabulin (TTI-237) fumarate is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell line).</p>Formule :C22H22ClF5N6O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :580.89CMX-2043
CAS :<p>CMX-2043 is a drug potentially to block oxidative damage and activate cell survival pathways.</p>Formule :C16H26N2O6S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :406.52BCR-ABL-IN-8
CAS :<p>BCR-ABL-IN-8 (compound 26f) is a BCR-ABL inhibitor featuring a trimethoxy group [1].</p>Formule :C30H33N7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :571.63
