Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1382 produits trouvés pour "Signalisation du cytosquelette"
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2-Methylbutyrylcarnitine chloride
<p>2-Methylbutyrylcarnitine (chloride) acts as a gut microbial metabolite that targets integrin α2β1 on platelets, facilitating the activation of cytosolic phospholipase A2 (cPLA2) and enhancing platelet hyperresponsiveness. This compound further augments platelet hyperreactivity and promotes thrombus formation in mice. It is also characterized as a branched-chain acylcarnitine.</p>Formule :C12H24ClNO4Couleur et forme :SolidMasse moléculaire :281.78AB-3PRGD2
CAS :<p>AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.</p>Formule :C137H215IN30O45SCouleur et forme :SolidMasse moléculaire :3161.32Tubulin polymerization-IN-50
<p>Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cell</p>Formule :C24H20FN3O3Couleur et forme :SolidMasse moléculaire :417.43β-catenin-IN-7
<p>β-Catenin-IN-7 (Compound 9) is an inhibitor of β-catenin that disrupts its interaction with Tcf-4, consequently impeding Wnt-dependent gene expression, and</p>Formule :C17H13BrN2O2SCouleur et forme :SolidMasse moléculaire :389.27α-Linolenic Acid (sodium salt)
CAS :<p>α-Linolenic acid (ALA) is an essential fatty acid found in leafy green vegetables.</p>Formule :C18H29NaO2Couleur et forme :SolidMasse moléculaire :300.41Ac-MRGDH-NH2
<p>Ac-MRGDH-NH2 is a pentapeptide containing the RGD sequence. It is utilized in the synthesis of the diastereomeric prodrugs Λ- and Δ-[Ru(Ph2phen)2(κS,κN-(Ac-MRGDH-NH2))]Cl2. In these prodrugs, Ac-MRGDH-NH2 serves as a photolabile protecting group for the cytotoxic diruthenium aqua complexes [Ru(Ph2phen)2(OH2)2]2+, offering integrin targeting and photoactivation properties. Consequently, Ac-MRGDH-NH2 can be applied in studies exploring tumor-targeted photoactivatable chemotherapy.</p>Formule :C25H41N11O8SCouleur et forme :SolidMasse moléculaire :655.727hAChE-IN-1
<p>hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.</p>Formule :C22H24N4OCouleur et forme :SolidMasse moléculaire :360.45st-Ht31
CAS :<p>Ht-31 stearate: Blocks RII subunits of PKA & AKAP interaction in cells; cell-permeable.</p>Formule :C129H217N29O39Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2798.27αVβ8-IN-1
CAS :<p>αVβ8-IN-1 is an αVβ8 integrin inhibitor that suppresses the growth of multiple tumour cell lines (EMT6, CT26, KPC, TKCC-10).</p>Formule :C25H32ClN5O4Couleur et forme :SolidMasse moléculaire :502.01Microtubule-associated protein tau (26-44)
<p>Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.</p>Formule :C83H127N25O34SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2051.11FRATide
CAS :<p>FRATtide inhibits the phosphorylation of Axin and β-catenin, inhibits GSK-3 binding to Axin, and is a peptide derived from the GSK-3 binding protein.</p>Formule :C55H102N2O2Couleur et forme :SolidMasse moléculaire :823.433INY-03-041
<p>INY-03-041, a PROTAC pan-AKT degrader, targets AKT1/2/3 with IC50s: 2.0/6.8/3.5 nM; GDC-0068 + Lenalidomide fusion.</p>Formule :C44H56ClN7O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :798.41Osemitamab (FUT8-KO)
<p>Osemitamab (FUT8-KO) is a monoclonal antibody targeting claudin-18.2, expressed in CHO cells with a knockout of the fucosyltransferase 8 gene (FUT8). The absence of fucose heightens the antibody's ADCC effect. When combined with Capecitabine and Oxaliplatin, it can be used for G/GEJ cancer research.</p>Couleur et forme :Odour LiquidLarazotide
CAS :<p>Larazotide: octapeptide from V. cholerae, treats Coeliac disease by inhibiting paracellular permeability.</p>Formule :C32H55N9O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :725.83Tubulin inhibitor 36
<p>Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,</p>Formule :C16H13ClN6SCouleur et forme :SolidMasse moléculaire :356.83Abl Cytosolic Substrate
CAS :<p>Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ).</p>Formule :C64H101N15O16Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1336.58Crosstide
CAS :<p>Crosstide is a peptide analog of glycogen synthase kinase-3 (GSK-3) that functions as a natural substrate for Akt/PKB.</p>Formule :C48H77N17O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1164.23Pironetin
CAS :<p>Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.</p>Formule :C19H32O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.45Aberrant tau degrader 2
CAS :<p>Aberrant tau degrader 2 (Compound 4-12) acts as a degrader of tau protein and serves as a target protein ligand for the synthesis of PROTAC degrader C004019.</p>Formule :C19H27N7O3SCouleur et forme :SolidMasse moléculaire :433.528DynaMin inhibitory peptide, myristoylated
CAS :<p>Cell-permeable dynamin inhibitor; blocks its binding to amphiphysin, hindering endocytosis; curbs NMDA receptor internalization.</p>Formule :C61H107N19O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1330.64
