Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1382 produits trouvés pour "Signalisation du cytosquelette"
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Tubulin inhibitor 36
<p>Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,</p>Formule :C16H13ClN6SCouleur et forme :SolidMasse moléculaire :356.83DSPE-PEG3000-iRGD
<p>DSPE-PEG3000-iRGD is a PEG compound comprising DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrin and undergoes proteolytic cleavage within tumors to produce CRGDK/R, interacting with neuropilin-1. This results in tumor targeting and penetration capabilities. DSPE-PEG3000-iRGD is applicable in drug delivery.</p>Couleur et forme :Odour SolidCyclo(RGDfC) TFA
<p>Zelminemab (AMG-301) is a humanized monoclonal antibody targeting ADCYAP1R1 for use in neurological disorders.</p>Formule :C26H35F3N8O9SDegré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :692.67DPH
CAS :<p>DPH is a potent cell permeable activator of c-Abl. It shows potent enzymatic and cellular activity in stimulating c-Abl activation.</p>Formule :C18H13FN4O2Degré de pureté :99.65%Couleur et forme :SolidMasse moléculaire :336.32hAChE-IN-1
<p>hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.</p>Formule :C22H24N4OCouleur et forme :SolidMasse moléculaire :360.45(8R)-8-Hydroxyepoxyboetirane A
<p>(8R)-8-Hydroxyepoxyboetirane A is a neuroactivating compound that interacts with PKCδ-C1B. This compound binds into the PKC enzyme pocket through hydrogen bonds with glycine-253, leucine-251, and threonine-242. It induces the release of NRG1 and promotes the differentiation of neural stem cells into neurons. (8R)-8-Hydroxyepoxyboetirane A holds potential for research into nervous system disorders.</p>Couleur et forme :Odour SolidAD57
CAS :<p>AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.</p>Formule :C22H20F3N7ODegré de pureté :99.05%Couleur et forme :SoildMasse moléculaire :455.44Pironetin
CAS :<p>Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.</p>Formule :C19H32O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.45PTA001_A4
<p>PTA001_A4 (Anti-CDH17/Cadherin-17 Antibody) is a humanized antibody targeting CDH17/Cadherin-17 with anti-tumor activity and inhibits tumor cell growth.</p>Degré de pureté :95.8% (SDS-PAGE); 99.3% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.3% (SEC-HPLC)Couleur et forme :Odour Liquid19-O-Acetylchaetoglobosin A
CAS :<p>19-O-Acetylchaetoglobosin A, from C. globosum, inhibits actin polymerization and is cytotoxic to HeLa cells at 3.2-32 μg/ml.</p>Formule :C34H38N2O6Couleur et forme :SolidMasse moléculaire :570.686SIAIS178
CAS :<p>SIAIS178 is a potent and selective degrader of BCR-ABL based on PROTAC technology (IC50 of 24 nM).</p>Formule :C50H62ClN11O6S2Degré de pureté :98.07%Couleur et forme :SolidMasse moléculaire :1012.68Adhesamine diTFA
CAS :<p>Adhesamine diTFA, a dumbbell-shaped molecule, activates the MAPK/FAK pathway. It promotes adhesion and growth in mammalian cells and accelerates differentiation and enhances the survival rate of primary cultured mouse hippocampal neurons.</p>Formule :C28H32Cl2F6N8O6S2Couleur et forme :SolidMasse moléculaire :825.63CYP51/Hsp90-IN-1
<p>CYP51/Hsp90-IN-1 (Compound MM4) is a dual inhibitor of CYP51 and Hsp90. This compound exhibits antifungal activity against Candida albicans and effectively suppresses key fungal virulence factors. CYP51/Hsp90-IN-1 shows potential for research in treating invasive candidiasis.</p>Formule :C38H40F2N6O4Couleur et forme :SolidMasse moléculaire :682.76α2β1 Integrin Ligand Peptide
CAS :<p>The Asp-Gly-Glu-Ala (DGEA) amino acid domain of type I collagen interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular</p>Formule :C14H22N4O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :390.35huATN-658
<p>huATN-658 (MNPR-101) is a humanized monoclonal antibody inhibitor targeting the urokinase-type plasminogen activator receptor (uPAR). It effectively disrupts the interaction between uPAR and integrins, thereby inhibiting tumor cell proliferation, invasion, and migration. huATN-658 shows potential for research in breast cancer, particularly in cases of triple-negative breast cancer.</p>Couleur et forme :Odour LiquidEpothilone F
CAS :<p>Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.</p>Formule :C27H41NO7SCouleur et forme :SolidMasse moléculaire :523.68NMS-E973
CAS :<p>NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.</p>Formule :C22H22N4O7Degré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :454.43Box5 TFA
<p>Box5 TFA, a potent Wnt5a antagonist, impedes Wnt5a signaling, restricts Wnt5a-initiated Ca2+ release, and hampers cell migration, showing promise for melanoma</p>Formule :C32H51F3N6O15S2Couleur et forme :SolidMasse moléculaire :880.9Myrtucommulone
CAS :<p>Myrtucommulone is an inhibitor of the chaperonin activity of HSP60, correlating to LRP130 and LONP aggregation.</p>Formule :C38H52O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :668.81HSDVHK-NH2
CAS :<p>Potent antagonist of the integrin αvβ3-vitronectin interaction (IC50 = 25.72 nM). Blocks proliferation and induces apoptosis in HUVECs; antiangiogenic.</p>Formule :C30H48N12O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :720.78
