Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1382 produits trouvés pour "Signalisation du cytosquelette"
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Pre-084
CAS :<p>Pre-084 is a high affinity, selective σ1 agonist.</p>Formule :C19H28ClNO3Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :353.88Shepherdin 79-87 acetate
<p>Shepherdin 79-87 acetate is a peptidomimetic antagonist of the complex between Hsp90 and survivin, another key regulator of tumor cell viability.</p>Formule :C43H68N12O14SDegré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :1009.14AZ13705339 hemihydrate
<p>AZ13705339 hemihydrate: potent PAK1 inhibitor (IC50: 0.33 nM), also binds PAK1/2 (Kd: 0.28/0.32 nM), for cancer research.</p>Formule :C33H36FN7O3SH2OCouleur et forme :SolidMasse moléculaire :638.77Bexotegrast
CAS :<p>Bexotegrast (PLN-74809) is an αvβ6 and αvβ1 integrin inhibitor with antifibrotic properties for the study of idiopathic pulmonary fibrosis (IPF).</p>Formule :C27H36N6O3Degré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :492.61Alvespimycin
CAS :<p>Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.</p>Formule :C32H48N4O8Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :616.75FAK activator 1
CAS :<p>ZINC40099027 is a FAK activator that induces gastric mucosal repair in persistent aspirin-associated gastric injury.</p>Formule :C23H26F3N3O3Degré de pureté :99.19%Couleur et forme :SoildMasse moléculaire :449.47RO0270608
CAS :<p>RO0270608 is an α4β1/α4β7 integrin antagonist with anti-inflammatory activity for the study of allergic inflammatory responses.</p>Formule :C24H19Cl3N2O4Degré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :505.78Muromonab
CAS :<p>Muromonab (OKT3) is a mouse-derived antibody targeting the CD3 receptor, blocking all cytotoxic T cell functions.</p>Degré de pureté :95% - 97.51% (SEC-HPLC)Couleur et forme :LiquidNeurodazine
CAS :<p>Neurodazine is a neural inducer that promotes the differentiation of pluripotent cells into neuronal cells.</p>Formule :C27H21ClN2O3Degré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :456.92Bosutinib hydrate
CAS :<p>Bosutinib hydrate (SKI-606 hydrate) is a kinase inhibitor of BCR-ABL and Src tyrosine kinases for the study of leukemia.</p>Formule :C26H31Cl2N5O4Degré de pureté :99.87%Couleur et forme :SolidMasse moléculaire :548.46Etaracizumab
CAS :<p>Etaracizumab (LM 609) is a humanized monoclonal antibody targeting integrin αvβ3, inhibiting angiogenesis and melanoma growth, used in the study of melanoma.</p>Degré de pureté :96.77% (SEC-HPLC) - 99.32% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :144.3 (kDa)Vevorisertib trihydrochloride
CAS :<p>Vevorisertib trihydrochloride (ARQ 751 trihydrochloride) is ainhibitor of pan-AKT and AKT1-E17K mutations, inhibiting AKT1, AKT2 and AKT3.</p>Formule :C35H41Cl3N8ODegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :696.12Ruboxistaurin hydrochloride
CAS :<p>Ruboxistaurin HCl (LY 333531) selectively inhibits PKCβI/II with IC50 of 4.7/5.9 nM; much less effective on other PKC types and ATP-kinases.</p>Formule :C28H28N4O3·HClDegré de pureté :98.44% - 99.22%Couleur et forme :SolidMasse moléculaire :505.01H-Ile-Lys-Val-Ala-Val-OH
CAS :<p>H-Ile-Lys-Val-Ala-Val-OH can induce rapid differentiation of neural progenitor cells into neurons and neurite growth.</p>Formule :C25H48N6O6Degré de pureté :99.92%Couleur et forme :SolidMasse moléculaire :528.69Arg-Gly-Asp-Ser
CAS :<p>Arg-Gly-Asp-Ser (RGDS peptide) is a conserved tetrapeptide sequence found in fibronectin, and the von Willebrand factor.</p>Formule :C15H27N7O8Degré de pureté :98.29%Couleur et forme :SolidMasse moléculaire :433.42NQTrp
CAS :<p>NQTrp is an inhibitor of the aggregation of the tau protein with generic anti-amyloidogenic effects.</p>Formule :C21H16N2O4Degré de pureté :98.35%Couleur et forme :SolidMasse moléculaire :360.36Mps1-IN-2
CAS :<p>Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.</p>Formule :C26H36N6O3Degré de pureté :96.24% - 99.75%Couleur et forme :SolidMasse moléculaire :480.6WZU-13
CAS :<p>WZU-13 is an inhibitor of carboxylesterase (CES). At a concentration of 100 μM, WZU-13 suppresses 77% of CES activity.</p>Formule :C22H16N2OCouleur et forme :SolidMasse moléculaire :324.38Anti-Mouse CD3ε Antibody (145-2C11)
<p>Anti-Mouse CD3ε Antibody (145-2C11) is an antibody inhibitor targeting CD3ε in Armenian hamsters, in TCR formation and in T lymphocyte activation</p>Degré de pureté :99%Couleur et forme :Odour LiquidST-401
CAS :<p>ST-401, a microtubule-targeting agent (MTA), functions as a brain-penetrant microtubule (MT) assembly inhibitor. It disrupts microtubule (MT) function by gently and reversibly reducing MT assembly, which leads to mitotic delay and interphase cell death. ST-401 demonstrates potent antitumor activity.</p>Formule :C24H20N2OCouleur et forme :SolidMasse moléculaire :352.43Vepsitamab
CAS :<p>Vepsitamab (AMG 199), an anti-MUC17/CD3 BiTE, targets T cells and tumors for cell lysis and T cell activation.</p>Couleur et forme :LiquidPinatuzumab
CAS :<p>Pinatuzumab is a humanised monoclonal antibody targeting CD22, B-cell malignancies non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukaemia (CLL).</p>Degré de pureté :95%Couleur et forme :LiquidPasotuxizumab
CAS :<p>Pasotuxizumab (BAY 2010112) is a BiTE that targets PSMA & CD3 with K D s 47.0 & 9.4 nM, for mCRPC research.</p>Couleur et forme :LiquidTepoditamab
CAS :<p>Tepoditamab (MCLA-117) is a bispecific antibody targeting CLEC12A and CD3, inducing T cell lysis of AML cells.</p>Couleur et forme :LiquidGresonitamab
CAS :<p>Gresonitamab (AMG 910) is an HLE BiTE antibody targeting CD3+ T cells and CLDN18.2+ tumors, for adenocarcinoma research.</p>Couleur et forme :LiquidObrindatamab
CAS :<p>Obrindatamab: a humanized bispecific antibody targeting B7-H3/CD3, enhances CTL-mediated cancer cell killing.</p>Couleur et forme :LiquidEnlimomab
CAS :<p>Enlimomab (BI-RR 0001), a mouse IgG2a antibody, blocks leukocyte binding to ICAM-1, reducing inflammation and used in stroke research.</p>Couleur et forme :LiquidNivatrotamab
<p>Nivatrotamab: Humanized anti-GD2/CD3 bispecific antibody for neuroblastoma research.</p>Couleur et forme :Odour LiquidSemorinemab
CAS :<p>Semorinemab (RG6100) is a humanised monoclonal antibody targeting the N-terminal domain of tau protein with a Kd of 3.8 nM, suitable for Alzheimer's disease.</p>Degré de pureté :95% - 95%Couleur et forme :Liquid4-Desacetylvinblastine hydrazide
CAS :<p>Deacetylvinblastine hydrazide, a cytotoxic vinca alkaloid often conjugated with folic acid to produce EC145, a novel folate-receptor targeted agent.</p>Formule :C43H56N6O7Couleur et forme :SolidMasse moléculaire :768.94Raludotatug
CAS :<p>Raludotatug is a humanized antibody targeting cadherin-6 (CDH6). As part of the ADC Raludotatug deruxtecan, it shows promise in researching platinum-sensitive ovarian cancer.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidGosuranemab
CAS :<p>Gosuranemab (BMS-986168), a humanized IgG4 mAb, targets tau residues 15-22, and may aid in Alzheimer’s research.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidMeclofenamate sodium hydrate
CAS :<p>Meclofenamate sodium: a strong NSAID inhibiting leukocyte function—chemotaxis, degranulation, and radical production.</p>Formule :C14H12Cl2NNaO3Couleur et forme :SolidMasse moléculaire :336.15Posdinemab
CAS :<p>Posdinemab, a humanized IgG1κ antibody, targets the microtubule-associated protein tau (MAPT) [1].</p>Couleur et forme :LiquidPlamotamab
CAS :<p>Plamotamab (XmAb-13676) is a bispecific antibody targeting CD3 and CD20, recruiting T cells to destroy CD20+ tumors and causing mild hematologic reactions.</p>Couleur et forme :LiquidAnti-Mouse IL-1a Antibody (ALF-161)
<p>Anti-Mouse IL-1a Antibody is an IgG1 subtype inhibitor specific to mouse IL-1a, derived from the Armenian Hamster.</p>Degré de pureté :98%Couleur et forme :Odour LiquidUbamatamab
CAS :<p>Ubamatamab (REGN4018), a human bispecific antibody targeting Mucin 16 (MUC16) and CD3, exhibits potent antitumor activity [1].</p>Couleur et forme :LiquidOsemitamab
CAS :<p>Osemitamab (TST001) is a humanised monoclonal antibody targeting claudin-18.2, gastric/gastric-oesophageal junction adenocarcinoma, PDAC, and lung cancer.</p>Degré de pureté :95%Couleur et forme :LiquidVoxalatamab
CAS :<p>Voxalatamab (JNJ-63898081), an IgG4 bispecific antibody targeting PSMA and CD3, demonstrates anti-cancer efficacy in prostate cancer research [1].</p>Couleur et forme :LiquidVonsetamig
CAS :<p>Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.</p>Couleur et forme :LiquidFlotetuzumab
CAS :<p>Flotetuzumab (MGD006/S80880) is a CD123/CD3 bispecific DART antibody, reactivating T-cells for AML treatment.</p>Couleur et forme :LiquidPacanalotamab
CAS :<p>Pacanalotamab (AMG 420/BI-836909), a BiTE, directs T-cells to BCMA+ MM cells, causing lysis.</p>Couleur et forme :LiquidVibecotamab
CAS :<p>Vibecotamab, a bispecific antibody, targets CD123/CD3 for T-cell killing of tumors, promising for acute myeloid leukemia.</p>Couleur et forme :LiquidOS-2966
<p>OS-2966 is a humanised de-immunised monoclonal antibody that target Integrin b1/ITGB1/CD29, malignant gliomas, glioblastomas, and astrocytomas.</p>Degré de pureté :95%Couleur et forme :Odour LiquidRovelizumab
CAS :<p>Rovelizumab: humanized anti-CD11/CD18 antibody for MS, hemorrhagic shock, MI, and stroke research.</p>Couleur et forme :LiquidLixudebart
CAS :<p>Lixudebart is a humanised monoclonal antibody targeting CLDN1 (Claudin-1), which can be used to reverse organ fibrosis and reduce initial ALT/AST levels.</p>Degré de pureté :95%Couleur et forme :LiquidVatelizumab
CAS :<p>Vatelizumab is a humanised monoclonal antibody targeting Integrin α2β1 ( VLA-2, CD49b), which enhances the frequency of regulatory T cells multiple sclerosis.</p>Degré de pureté :95%Couleur et forme :LiquidLinvoseltamab
CAS :<p>Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/</p>Couleur et forme :LiquidCevostamab
CAS :<p>Cevostamab (BFCR4350A, RG6160, RO7187797) is a humanized BsAb IgG1 targeting FcRH5 on MM cells and CD3 on T cells to enhance T-cell-mediated MM cell killing.</p>Couleur et forme :LiquidOdronextamab
CAS :<p>Odronextamab, a fully human, hinge-stabilized IgG4-based bispecific antibody, targets CD3 receptors on T cells and CD20 receptors on B cells [1].</p>Couleur et forme :LiquidPavurutamab
CAS :<p>Pavurutamab (AMG-701) is a bispecific T cell engager targeting CD3 and BCMA with extended half-life, designed to treat MM.</p>Couleur et forme :Liquid17-AEP-GA
CAS :<p>17-AEP-GA is an HSP90 antagonist and a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.</p>Formule :C34H50N4O8Degré de pureté :97.77% - 99.56%Couleur et forme :SolidMasse moléculaire :642.78Tubulin polymerization-IN-2
CAS :<p>Tubulin-IN-2, anticancer β-tubulin binder, IC50 0.92 μM, effective against various cancers.</p>Formule :C17H12F2N2O2Couleur et forme :SolidMasse moléculaire :314.29Meclofenamic acid
CAS :<p>Meclofenamic acid: non-selective gap-junction blocker, FTO inhibitor, anti-inflammatory.</p>Formule :C14H11Cl2NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :296.15SB273005
CAS :<p>SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for αvβ3 receptor and αvβ5 receptor, respectively.</p>Formule :C22H24F3N3O4Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :451.44N-Desmethylnefopam
CAS :<p>N-Desmethylnefopam is the main Nefopam metabolite .</p>Formule :C16H17NODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :239.31Ionomycin calcium
CAS :<p>Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.</p>Formule :C41H70CaO9Degré de pureté :98% - 98.11%Couleur et forme :SolidMasse moléculaire :747.07Phorbol 12,13-dibutyrate
CAS :<p>Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that induces contraction of isolated rabbit vascular smooth muscle.</p>Formule :C28H40O8Degré de pureté :99.32% - 99.37%Couleur et forme :SolidMasse moléculaire :504.61D-GsMTx4 TFA
<p>D-GsMTx4 TFA, a selective spider venom peptide, is a TRPC1/6 and Piezo2 inhibitor that inhibits cation-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families, blocks cation-selective stretch-activated channels (SACs), and attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglia reactivity. toxicity and microglia reactivity.D-GsMTx4 TFA prevented myocardial infarction in a mouse model of ischemia/reperfusion and can be used to characterize the role of excitatory MSCs in normal physiology and pathology.</p>Formule :C187H279F3N48O48S6Degré de pureté :99.29% - 99.65%Couleur et forme :SoildMasse moléculaire :4216.93IPA-3
CAS :<p>IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6).</p>Formule :C20H14O2S2Degré de pureté :97.40%Couleur et forme :SolidMasse moléculaire :350.45Tirofiban
CAS :<p>Tirofiban (L700462) (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of 9 nM.</p>Formule :C22H36N2O5SDegré de pureté :99.83%Couleur et forme :SolidMasse moléculaire :440.6Auristatin F
CAS :<p>Auristatin F is an effective inhibitor of microtubule and vascular damaging agent. Auristatin F can be used in antibody-drug conjugates.</p>Formule :C40H67N5O8Degré de pureté :98.41% - 99.25%Couleur et forme :SolidMasse moléculaire :745.99Mps1-IN-1
CAS :<p>Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )</p>Formule :C28H33N5O4SDegré de pureté :98.33%Couleur et forme :SolidMasse moléculaire :535.66BAY1217389
CAS :<p>BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).</p>Formule :C27H24F5N5O3Degré de pureté :98.14% - 99.42%Couleur et forme :SolidMasse moléculaire :561.5AS1938909
CAS :<p>AS1938909: SHIP2 inhibitor boosts Akt phosphorylation, glucose use, and uptake via GLUT1 in L6 myotubes.</p>Formule :C19H13Cl2F2NO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.28IQTub4P
CAS :<p>IQTub4P is a potent inhibitor of microtubules. IQTub4P exhibits cytotoxicity in HeLa cells (EC50: 170 nM).</p>Formule :C19H18NNa2O8PCouleur et forme :SolidMasse moléculaire :465.305HSP90-IN-14
CAS :<p>HSP90-IN-14 inhibits Hsp90 (Kd=0.26 μM) and fights influenza A/H3N2, A/H1N1, B with EC50 of 2.6, 3.9, 17 μM in MDCK cells.</p>Formule :C14H8Cl2N4O4SCouleur et forme :SolidMasse moléculaire :399.21Microtubule inhibitor 4
CAS :<p>Microtubule inhibitor 4 (Compound 2) blocks polymerization, toxic to HT-29 cells (IC50: 2.1 nM).</p>Formule :C25H23FN4O3Couleur et forme :SolidMasse moléculaire :446.47NC9 TG2 inhibitor
CAS :<p>NC9 is an irreversible inhibitor of transglutaminase 2 (TG2) and also inhibits Factor XIIIA (FXIIIA).</p>Formule :C35H47N5O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :697.84Antiproliferative agent-30
CAS :<p>Antiproliferative agent-30 (Compound 8g) demonstrates broad-spectrum antiproliferative activity, with IC50 values of 0.054 nM, 0.008 nM, and 0.144 nM against</p>Formule :C24H26N4O4Couleur et forme :SolidMasse moléculaire :434.49Tubulin polymerization-IN-42
CAS :<p>Tubulin polymerization-IN-42 (compound 10j), an indole-substituted furanone, inhibits tubulin polymerization and exhibits anti-cancer properties [1].</p>Formule :C22H21NO5Couleur et forme :SolidMasse moléculaire :379.41CCT251236
CAS :<p>CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen.</p>Formule :C32H32N4O5Degré de pureté :98.82% - 99.89%Couleur et forme :SolidMasse moléculaire :552.62GR 144053 trihydrochloride
CAS :<p>platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist</p>Formule :C18H30Cl3N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :454.82Alyssin
CAS :<p>Alyssin: sulforaphane analog, antioxidant; boosts Nrf2 and phase II enzymes in cancer cells; lowers PAH metabolism, reducing cancer risk in vitro.</p>Formule :C7H13NOS2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :191.31CH5164840
CAS :<p>CH5164840: strong HSP90 blocker; excels in NSCLC treatment; boosts erlotinib efficacy on EGFR-mutant tumors.</p>Formule :C19H23N5O2SCouleur et forme :SolidMasse moléculaire :385.48Tubulozole
CAS :<p>Tubulozole blocks mitosis by inhibiting microtubule dynamics, leading to cell cycle arrest and apoptosis.</p>Formule :C23H23Cl2N3O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :508.42SEW84
CAS :<p>SEW84, an Aha1-stimulated Hsp90 inhibitor, has an IC50 of 0.3 μM, aiding protein deposition disease research.</p>Formule :C19H14F4N4OSCouleur et forme :SolidMasse moléculaire :422.4Hsp90-Cdc37-IN-1
CAS :<p>Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor (IC50: 140 nM) that inhibit cell migration and reverse drug resistance.</p>Formule :C43H57FN2O6SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :748.99PP2A Cancerous-IN-1
CAS :<p>PP2A Cancerous-IN-1 is a potent inhibitor of CIP2A (Cancerous inhibitor of PP2A) and p-Akt that exhibits potent anti-proliferative effects.</p>Formule :C30H24N4O3Couleur et forme :SolidMasse moléculaire :488.54OXi8007
CAS :<p>OXi8007, a water-soluble prodrug for OXi8006, disrupts vasculature and exhibits strong cytotoxicity against DU-145 cancer cells.</p>Formule :C26H24NNa2O10PCouleur et forme :SolidMasse moléculaire :587.428Hsp90-IN-17
CAS :<p>Hsp90-IN-17 (Example 5) is an inhibitor of HSP90, applicable in researching proliferative diseases, including cancer and neurodegenerative conditions.</p>Formule :C21H20N4O7Couleur et forme :SolidMasse moléculaire :440.41Chrysotobibenzyl
CAS :<p>Chrysotobibenzyl from Dendrobium pulchellum stems may trigger cell death in detached cells and hinder lung cancer growth.</p>Formule :C19H24O5Couleur et forme :SolidMasse moléculaire :332.39Hydromethylthionine HBr
CAS :<p>Hydromethylthionine (LMTM/Leucomethylene Blue) inhibits tau in Alzheimer's/frontotemporal dementia and improves brain function.</p>Formule :C16H21Br2N3SCouleur et forme :SolidMasse moléculaire :447.233CHPG
CAS :<p>CHPG is a selective mGluR5 agonist protects against traumatic brain injury.activates the ERK and Akt pathways, It also alleviates LPS-induced inflammation.</p>Formule :C8H8ClNO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :201.61Heat Shock Protein Inhibitor II
CAS :<p>Hsp inhibitor II, an active benzylidene lactam, blocks inducible Hsp synthesis, reduces tumor thermotolerance, and enhances AmB effects on A. fumigatus.</p>Formule :C12H11NO3Couleur et forme :SolidMasse moléculaire :217.22Tau-aggregation-IN-1
CAS :<p>Tau-aggregation-IN-1 is a dopamine D2 and D3 receptor agonist and an inhibitor of tau441 protein aggregation (IC50: 21 μM).</p>Formule :C28H37N5O2SCouleur et forme :SolidMasse moléculaire :507.69AK963
CAS :<p>AK963 (40708899) is a powerful PAK1 inhibitor reducing gastric cancer cell growth via the PAK1-NFκB-CyclinB1 pathway.</p>Formule :C16H18N2OCouleur et forme :SolidMasse moléculaire :254.33(R)-TTBK1-IN-1
CAS :<p>(R)-TTBK1-IN-1: potent, selective brain-penetrant TTBK1 inhibitor, studies Alzheimer’s & tauopathies.</p>Formule :C18H19N5O2Couleur et forme :SolidMasse moléculaire :337.38BMS-688521
CAS :<p>BMS-688521 is an LFA-1/ICAM interaction inhibitor, a small molecule antagonist of LFA-1 with potential anti-inflammatory activity.</p>Formule :C26H19Cl2N5O4Degré de pureté :98.87%Couleur et forme :SolidMasse moléculaire :536.37Syntelin
CAS :<p>Syntelin: a selective CENP-E inhibitor with an IC50 of 160 nM; distinct from GSK923295, effective on resistant mutants.</p>Formule :C21H20N6O2S3Couleur et forme :SolidMasse moléculaire :484.62LS-104
CAS :<p>LS-104 is a JAK2 inhibitor.</p>Formule :C19H16N2O3Couleur et forme :SolidMasse moléculaire :320.34Tubulin polymerization-IN-25
CAS :<p>Tubulin polymerization-IN-25 inhibits tubulin (IC50: 1.11 μM) & FTase (IC50: 0.39 μM), and is cytotoxic to cancer cells, halting growth.</p>Formule :C24H18N2O3SCouleur et forme :SolidMasse moléculaire :414.48AKT-IN-8
CAS :<p>AKT-IN-8 is a potent inhibitor of AKT, acting on AKT1 (IC50: 4.46 nM), AKT2 (IC50: 2.44 nM) and AKT3 (IC50: 9.47 nM).</p>Formule :C22H25ClN6O3Couleur et forme :SolidMasse moléculaire :456.93AKT-IN-5
CAS :<p>AKT-IN-5, an Akt inhibitor, targets Akt1/Akt2 with IC50s: 450/400 nM.</p>Formule :C23H20N4O2Couleur et forme :SolidMasse moléculaire :384.43Zalunfiban
CAS :<p>RUC-4 is an aIIb 3 antagonist. It is also used for prehospital therapy of myocardial infarction.</p>Formule :C16H18N8O2SCouleur et forme :SolidMasse moléculaire :386.43cemadotin free base
CAS :<p>Cemadotin free base(LU103793 free base) is a novel anti-limiting peptide , an analog of Dolastatin 15, a naturally occurring cytotoxic peptide that blocks</p>Formule :C35H56N6O5Degré de pureté :98.70% - 99.64%Couleur et forme :SolidMasse moléculaire :640.86Zarilamide
CAS :<p>Zarilamide disrupts microtubules, inhibiting mitosis in Phytophthora capsici zoospore cysts.</p>Formule :C11H11ClN2O2Couleur et forme :SolidMasse moléculaire :238.67Tubulin polymerization-IN-20
CAS :<p>Tubulin aggregation-IN-20, a potent inhibitor, may be studied for breast and drug-resistant colon cancers.</p>Formule :C25H24FNO5Couleur et forme :SolidMasse moléculaire :437.46Tubulin/MMP-IN-1
<p>Tubulin/MMP-IN-1 inhibits tubulin, MMP, and cancer cell growth; disrupts cell cycles and induces apoptosis.</p>Formule :C38H44NO9PCouleur et forme :SolidMasse moléculaire :689.73HSP90-IN-20
CAS :<p>HSP90-IN-20, a potent inhibitor of HSP90, exhibits an IC50 of ≤10 μM, indicating its potential application in cancer research.</p>Formule :C26H32N4O4Couleur et forme :SolidMasse moléculaire :464.56Tubulin inhibitor 12
CAS :<p>New tubulin inhibitor 12 (Hit 9); potent anti-cancer agent; IC50=25.3 μM; strong anti-tumor effect.</p>Formule :C24H20N2OCouleur et forme :SolidMasse moléculaire :352.43BCR-ABL1-IN-1
CAS :<p>BCR-ABL1-IN-1: potent, orally active ABL kinase inhibitor with high specificity, promising for CNS research.</p>Formule :C18H12F3N3O2Couleur et forme :SolidMasse moléculaire :359.3KY-04031
CAS :<p>KY-04031 is an inhibitor of p21-activated kinase 4.</p>Formule :C21H20N8OCouleur et forme :SolidMasse moléculaire :400.44AFG210
CAS :<p>AFG210 is a novel first-generation “type II” FLT3 inhibitor.</p>Formule :C19H14F3N3O2Couleur et forme :SolidMasse moléculaire :373.33BCR-ABL-IN-5
CAS :<p>BCR-ABL-IN-5: Bcr-Abl kinase inhibitor, IC50: Bcr-AblWT 0.014 μM, Bcr-AblT315I 0.45 μM; anti-leukemia cell growth.</p>Formule :C25H21Cl2N5O2Couleur et forme :SolidMasse moléculaire :494.37Iso-Fludelone
CAS :<p>Iso-Fludelone: a stable, soluble, potent, 3rd-gen epothilone B inhibiting cell division and inducing apoptosis, with low toxicity.</p>Formule :C27H36F3NO6Couleur et forme :SolidMasse moléculaire :527.5710-DEBC hydrochloride
CAS :<p>10-DEBC hydrochloride, a selective Akt inhibitor demonstrating an IC50 value of 1.28 μM, is identified as a novel anti-tuberculosis compound [1] [2].</p>Formule :C20H26Cl2N2OCouleur et forme :SolidMasse moléculaire :381.34DRP1i27
CAS :<p>DRP1i27 inhibits human Drp1 at GTPase site, prevents mitochondrial fission, and shields cells from ischemia-reperfusion damage.</p>Formule :C20H26N6OCouleur et forme :SolidMasse moléculaire :366.46KY-04045
CAS :<p>KY-04045 is a PAK4 inhibitor.</p>Formule :C13H14BrN5Couleur et forme :SolidMasse moléculaire :320.19NAMI-A
CAS :<p>NAMI-A is a ruthenium-based compound with selective activity against tumor metastasis.NAMI-A inhibits cancer cell adhesion and migration.</p>Formule :C8H15Cl4N4ORuSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.18SSTC3
CAS :<p>SSTC3 is a casein kinase 1α (CK1α) activator with potential antitumor activity that inhibits WNT signaling.</p>Formule :C23H17F3N4O3S2Degré de pureté :98.65% - 99.94%Couleur et forme :SolidMasse moléculaire :518.53CHMFL-ABL-053
CAS :<p>CHMFL-ABL-053: potent, selective BCR-ABL/SRC/p38 inhibitor (IC50: 70/90/62 nM). Orally available, potential CML drug.</p>Formule :C28H26F3N7O2Couleur et forme :SolidMasse moléculaire :549.55BuChE-IN-5
CAS :<p>"BuChE-IN-5 is a potent inhibitor with an IC50 of 1.94 μM and shows promise for Alzheimer's research."</p>Formule :C25H35N3Couleur et forme :SolidMasse moléculaire :377.57Microtubule inhibitor 5
CAS :<p>Compound 17f, a potent microtubule inhibitor, shows strong cytotoxicity in NCI-H460 cells with an IC50 of 154.5 nM and high cell permeability.</p>Formule :C22H15FN2O4Couleur et forme :SolidMasse moléculaire :390.36AJH-836
CAS :<p>AJH-836 is a compound that activates Munc13-1 and PKC ε/α, demonstrating a dissociation constant (Kd) of 4.5 nM for PKCα, and facilitates the translocation of</p>Formule :C22H38O5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :382.53Tubulin inhibitor 27
CAS :<p>DYT-1 Tubulin inhibitor 27, IC50: 25.6 μM, hinders tubulin polymerization, displays anti-angiogenic and antitumor effects.</p>Formule :C21H19NO4Couleur et forme :SolidMasse moléculaire :349.38Tubulin polymerization-IN-10
CAS :<p>Tubulin polymerization-IN-10 inhibits tubulin polymerization with 4.25 μM IC50 and has anti-tumor properties.</p>Formule :C18H21NO6SCouleur et forme :SolidMasse moléculaire :379.43HSP90-IN-22
CAS :<p>HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor exhibiting antiproliferative activity, with IC50 values of 3.65 μM in MCF7 breast cancer cells and 2.71 μM in</p>Formule :C25H30N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :434.53YM-1
CAS :<p>YM-1, a stable MKT-077 analog, inhibits Hsp70 orally, kills HeLa cells, and boosts p53 and p21 proteins.</p>Formule :C20H20ClN3OS2Couleur et forme :SolidMasse moléculaire :417.98Sibrafiban
CAS :<p>Sibrafiban (RO 48-3657), an oral, nonpeptide prodrug, inhibits platelet aggregation as a selective IIb/IIIa antagonist.</p>Formule :C20H28N4O6Couleur et forme :SolidMasse moléculaire :420.46Neuroinflammatory-IN-3
CAS :<p>Neuroinflammatory-IN-3 is a potent tubulin inhibitor with anti-neuroinflammatory and antitumor properties.</p>Formule :C19H19ClO3Couleur et forme :SolidMasse moléculaire :330.81Tubulin polymerization-IN-36
CAS :<p>Tubulin polymerization-IN-36, a cancer research agent for lymphomas, inhibits tubulin at the colchicine site with IC50 of 2.8 µM.</p>Formule :C18H18N2O3Couleur et forme :SolidMasse moléculaire :310.35Tubulin polymerization-IN-16
CAS :<p>Compound 5g is a potent tubulin aggregation inhibitor, disrupting microtubules and causing G2/M arrest in SGC-7901 cells.</p>Formule :C24H27N5O5Couleur et forme :SolidMasse moléculaire :465.5BCR-ABL-IN-6
CAS :<p>BCR-ABL-IN-6, an imatinib derivative, inhibits Bcr-AblWT (4.6 nM IC50) and T315I (277 nM), for chronic myeloid leukemia study.</p>Formule :C27H22F3N5O2Couleur et forme :SolidMasse moléculaire :505.49Retaspimycin
CAS :<p>Retaspimycin is a potent and water-soluble Hsp90 inhibitor(EC50s of 119 nM for both Hsp90 and Grp9).</p>Formule :C31H45N3O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :587.7Tubulin polymerization-IN-15
CAS :<p>Tubulin polymerization-IN-15 (compound 4) is a highly effective inhibitor of tubulin polymerization, with significant potential in cancer research [1].</p>Formule :C18H17N3O4Couleur et forme :SolidMasse moléculaire :339.35Tubulin inhibitor 18
CAS :<p>"Tubulin inhibitor 18 (5j), a potent chalcone, uniquely structured for cancer research."</p>Formule :C22H26O5Couleur et forme :SolidMasse moléculaire :370.44Tubulin polymerization-IN-18
CAS :<p>Tubulin aggregation-IN-18 (compound 3) is a potent tubulin aggregation inhibitor with potential for breast cancer and drug-resistant colon cancer studies.</p>Formule :C25H25NO6Couleur et forme :SolidMasse moléculaire :435.47GNF-1331
CAS :<p>GNF-1331: potent, selective oral porcupine inhibitor; IC50=12 nM; targets aberrant Wnt signaling in cancers.</p>Formule :C20H20N6O2S2Couleur et forme :SolidMasse moléculaire :440.54Synstab A
CAS :<p>Synstab A is a microtubule stabilizer.</p>Formule :C15H13BrCl3N3O3SCouleur et forme :SolidMasse moléculaire :501.61KUNB31
CAS :<p>KUNB31 is a potent and selective inhibitor of Hsp90β.</p>Formule :C19H18N2O3Couleur et forme :SolidMasse moléculaire :322.36Microtubule inhibitor 7
CAS :<p>Compounds 17o and 17p have IC50s of 14.0 nM and 2.9 nM respectively, in NCI-H460 cancer cells, showing potent activity.</p>Formule :C25H19FN2O5Couleur et forme :SolidMasse moléculaire :446.43(S)-Dolaphenine hydrochloride
CAS :<p>(S)-Dolaphenine hydrochloride is a useful componet of compound synthesis.</p>Formule :C11H13ClN2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :240.75Dihydrocytochalasin B
CAS :<p>Dihydrocytochalasin B (H2CB) is a cell division inhibitor that inhibits cytokinesis and alters cell morphology.</p>Formule :C29H39NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :481.62MK-0668
CAS :<p>MK-0668 is a very potent and orally active very late antigen-4 antagonist.</p>Formule :C31H30Cl2N6O6SCouleur et forme :SolidMasse moléculaire :685.58Tau tracer 1
CAS :<p>Tau tracer 1 is a radiopharmaceutical for imaging Tau aggregates linked to neurodegenerative disease diagnosis.</p>Formule :C34H23N5O2Couleur et forme :SolidMasse moléculaire :533.591Deox B 7,4
CAS :<p>Deox B 7,4 is a reversible microtubule inhibitor that acts by increasing lysosomal V-ATPase activity and lysosome acidity.</p>Formule :C18H18O5Couleur et forme :SolidMasse moléculaire :314.33SW02
CAS :<p>SW02 is a potent ATPase activator of Hsp70 (EC50: 150 μM). SW02 is able to accumulate total tau and phosphorylated tau (pTau).</p>Formule :C19H23BrN2O5Couleur et forme :SolidMasse moléculaire :439.3Tubulin polymerization-IN-30
CAS :<p>Compound 6e inhibits tubulin polymerization, disrupts microtubules, halts G2/M phase, and targets HeLa, SGC-7901, A549 with low IC50.</p>Formule :C22H25N5O3Couleur et forme :SolidMasse moléculaire :407.47Tubulin inhibitor 29
CAS :<p>Compound 3c, a tubulin inhibitor, blocks assembly at colchicine site with IC50 of 1.2 μM; anti-proliferative IC50 7.5 μM in MCF-7 cells.</p>Formule :C12H8F2O2S2Couleur et forme :SolidMasse moléculaire :286.32Microtubule inhibitor 6
CAS :<p>Compound 17o inhibits microtubules, toxic to NCI-H460, BxPC-3, HT-29 cells (IC50: 14.0, 6.6, 7.0 nM), blocks polymerization.</p>Formule :C24H19FN2O5Couleur et forme :SolidMasse moléculaire :434.42Tubulin inhibitor 31
<p>Tubulin inhibitor 31: potent with 4 µM IC50, anti-proliferative, inhibits HUVEC migration.</p>Formule :C22H19NO2Couleur et forme :SolidMasse moléculaire :329.39BCR-ABL-IN-1
CAS :<p>BCR-ABL-IN-1 is a BCR-ABL tyrosine kinase inhibitor (pIC50: 6.46) and may be used in the research of chronic myelogenous leukemia.</p>Formule :C23H21F4N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :459.44PD-173956
CAS :<p>PD-173956 is an inhibitor of the Src family tyrosine kinases.</p>Formule :C20H13Cl2FN4OCouleur et forme :SolidMasse moléculaire :415.25Tubulin polymerization-IN-7
CAS :<p>Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases.</p>Formule :C28H24N4O6SCouleur et forme :SolidMasse moléculaire :544.58PF-06651481-00
CAS :<p>PF-06651481-00 (Bosutinib Isomer I) is a Bosutinib analog and a Bcr-Abl inhibitor.</p>Formule :C26H29Cl2N5O3Degré de pureté :97.01%Couleur et forme :SolidMasse moléculaire :530.45β-glycosidase-IN-1
CAS :<p>β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.</p>Formule :C13H23NO5Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :273.33TCS 2314
CAS :<p>TCS 2314 is an orally active and selective very late antigen-4 antagonist (IC50: 4.4 nM).</p>Formule :C28H34N4O6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :522.59Anticancer agent 60
CAS :<p>Anticancer agent 60 hinders HepG2 cell growth with IC50 of 4.13 μM and suppresses tumors in HepG2 mouse model.</p>Formule :C27H33N5O4SCouleur et forme :SolidMasse moléculaire :523.65Cevipabulin
CAS :<p>Cevipabulin (TTI-237) is a microtubule-active antitumor compound and inhibits the binding of [3H] vinblastine to tubulin (IC50: 18-40 nM in the human tumor cell</p>Formule :C18H18ClF5N6ODegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :464.82Mps-BAY2b
CAS :<p>Mps-BAY2b is a novel MPS1 inhibitor.</p>Formule :C20H23N5OCouleur et forme :SolidMasse moléculaire :349.43Mps1-IN-4
CAS :<p>Mps1-IN-4 is a compound that selectively inhibits Monopolar spindle 1 (Mps1), exhibiting antiproliferative properties useful in cancer research.</p>Formule :C26H31F3N6O2Couleur et forme :SolidMasse moléculaire :516.56AP 24149
CAS :<p>AP 24149, a potent dual inhibitor targeting Src and Abl, exhibits IC50 values of 9.1 nM for Src and 3.6 nM for Abl, respectively.</p>Formule :C23H24N5OPCouleur et forme :SolidMasse moléculaire :417.44SB26019
CAS :<p>SB26019: Potent anti-neuroinflammation; inhibits NF-κB via α-tubulin monomers preventing p65 translocation.</p>Formule :C24H20O4Couleur et forme :SolidMasse moléculaire :372.41YW1159
CAS :<p>YW1159 is an inhibitor of Wnt signaling.</p>Formule :C19H14FN5OCouleur et forme :SolidMasse moléculaire :347.35AMXI-5001
CAS :<p>AMXI-5001: potent oral parp1/2 inhibitor, blocks microtubules, strong anti-cancer effects, lower IC50s, and can shrink large tumors.</p>Formule :C25H20FN5O3Couleur et forme :SolidMasse moléculaire :457.46Tubulin polymerization-IN-21
CAS :<p>Tubulin polymerization-IN-21 disrupts microtubules, affects glucose metabolism, and has anticancer properties.</p>Formule :C30H29NO7Couleur et forme :SolidMasse moléculaire :515.55AM-9635
CAS :<p>AM-9635: Potent PI3Kδ inhibitor, cellular IC50 4.2 nM, reduces IgG/IgM, well-tolerated, affects cell growth/division.</p>Formule :C19H14F2N8Couleur et forme :SolidMasse moléculaire :392.36Clathrin-IN-2
CAS :<p>Clathrin-IN-2: CME inhibitor, IC50 - 2.3μM; also blocks dyn I GTPase, IC50 - 7.7μM.</p>Formule :C17H18Br2N2OCouleur et forme :SolidMasse moléculaire :426.15Tubulin inhibitor 20
CAS :<p>Tubulin inhibitor 20 (compound 1) shows the potential for the cancer research that is a potent tubulin inhibitor [1].</p>Formule :C19H18O4Couleur et forme :SolidMasse moléculaire :310.34BIIB028
CAS :<p>BIIB028: Hsp90 inhibitor, may degrade oncogenic proteins, potentially hindering tumor growth.</p>Formule :C19H21ClN5O5PCouleur et forme :SolidMasse moléculaire :465.83Tubulin inhibitor 26
CAS :<p>Compound 3c, a potent indazole-based tubulin inhibitor, halts G2/M phase and induces apoptosis in various cancers without weight loss in mice.</p>Formule :C17H19N3O3Couleur et forme :SolidMasse moléculaire :313.35O-GlcNAcase-IN-4
CAS :<p>O-GlcNAcase-IN-4, an inhibitor from patent WO2018140299A1, may aid in neurodegenerative disease research.</p>Formule :C16H22FN5O3SCouleur et forme :SolidMasse moléculaire :383.44BMS-587101
CAS :<p>BMS-587101 is a small molecule antagonist of LFA-1, which can reduce inflammation and joint destruction in the mouse model of arthritis.</p>Formule :C26H20Cl2N4O4SCouleur et forme :SolidMasse moléculaire :555.43Tubulin polymerization-IN-37
CAS :<p>Tubulin polymerization-IN-37 inhibits tubulin polymerization at the colchicine site (IC50: 2.3 μΜ), potentially aiding lymphoma research.</p>Formule :C19H20N2O4Couleur et forme :SolidMasse moléculaire :340.37BOP sodium
CAS :<p>BOP sodium salt is an inhibitor of alpha9beta1 and alpha4beta1 integrin.</p>Formule :C25H29N3NaO7SCouleur et forme :SolidMasse moléculaire :538.57THK-5117
CAS :<p>THK-5117, a tau PET probe, has a high tau fibril affinity (Ki 10.5 nM) and binds well to AD brain aggregates.</p>Formule :C19H19FN2O2Couleur et forme :SolidMasse moléculaire :326.36Integrin modulator 1
CAS :<p>Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.</p>Formule :C13H14N2O4Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :262.26XVA143
CAS :<p>XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.</p>Formule :C25H21Cl2N3O8Couleur et forme :SolidMasse moléculaire :562.36Debio 0617B
CAS :<p>Debio 0617B inhibits kinases for AML stem cell treatment, targeting JAK, ABL, SRC, and STAT3-related tumours.</p>Formule :C28H23ClF3N7O2Couleur et forme :SolidMasse moléculaire :581.98Antitumor agent-68
CAS :<p>Potent Antitumor-68 inhibits tubulin, IC50: 3.6μM HeLa, 3.8μM MCF-7; also scavenges ROS/DPPH dose-dependently.</p>Formule :C17H11NO2Couleur et forme :SolidMasse moléculaire :261.27Antitumor agent-71
CAS :<p>Antitumor Agent-71 inhibits tubulin aggregation; IC50 of 3.98-15.70 μM against cancer cells.</p>Formule :C26H31N5O4SCouleur et forme :SolidMasse moléculaire :509.62BMS-358233
CAS :<p>BMS-358233 is an effective LCK inhibitor with excellent cell activity against T cell proliferation.</p>Formule :C25H25ClN6O2SCouleur et forme :SolidMasse moléculaire :509.02PU24FCl
CAS :<p>PU24FCl is a specific inhibitor of tumor Hsp90.</p>Formule :C20H21ClFN5O3Couleur et forme :SolidMasse moléculaire :433.86KIF18A-IN-4
CAS :<p>KIF18A-IN-4: Non-competitive KIF18A inhibitor, IC50 6.16 μM, targets mitotic kinesins/kinases, anti-tumor.</p>Formule :C22H27N3O3SCouleur et forme :SolidMasse moléculaire :413.53Sabeluzole
CAS :<p>Sabeluzole (R-58735) has antiepileptic and cognitive enhancing properties and may be used in the study of Alzheimer's disease.</p>Formule :C22H26FN3O2SDegré de pureté :98.51%Couleur et forme :SolidMasse moléculaire :415.52Valategrast hydrochloride
CAS :<p>Valategrast hydrochloride (R411), a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment of asthma.</p>Formule :C30H33Cl4N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :641.41αvβ1 integrin-IN-1 TFA (1689540-62-2 free base)
<p>αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).</p>Formule :C28H35F3N6O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :672.67K-80003
CAS :<p>K-80003(TX-803) is a potent retinol-like X-receptor-alpha regulator that inhibits TRxrα-dependent Akt activation and tumor cell growth.</p>Formule :C22H21FO2Degré de pureté :99.76%Couleur et forme :SolidMasse moléculaire :336.4PS315
CAS :<p>PS315, a PS48 derivative, allosterically inhibits PKCζ/η (IC50: 10/30 μM), targeting aPKC's PIF-pocket, with anti-cancer properties.</p>Formule :C23H19ClO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :362.85AKT-IN-2
CAS :<p>AKT-IN-2 is a selective, and orally bioavailable AKT inhibitor (IC50: 5 nM for AKT1).</p>Formule :C25H34F3N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :505.58Balamapimod
CAS :<p>Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.</p>Formule :C30H32ClN7OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :574.14GB1874
CAS :<p>GB1874 is an inhibitor of the Wnt pathway targeting β-catenin-TCF4 protein-protein interaction (PPI), affecting proliferation in Wnt-dependent CRC cells.</p>Formule :C24H27N3O2SCouleur et forme :SolidMasse moléculaire :421.56AMP-PCP
CAS :<p>AMP-PCP is an ATP analog and can bind to the Hsp90 N-terminal domain (Kd: 3.8 μM). AMP-PCP binding favors the formation of the active homodimer of Hsp90.</p>Formule :C11H18N5O12P3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :505.21SR31527
CAS :<p>SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.</p>Formule :C15H14ClN3OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :319.81Eg5 Inhibitor V, trans-24
CAS :<p>Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.</p>Formule :C26H21N3O3Degré de pureté :99.75%Couleur et forme :SolidMasse moléculaire :423.46BBO-10203
CAS :<p>BBO-10203 is an oral small molecule that disrupts PI3Kα-Ras interaction, inhibits Akt signaling selectively, and targets KRAS-mutant tumors.</p>Formule :C34H30F2N6O3SDegré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :640.7ZINC194100678
CAS :<p>ZINC194100678 is an effective PAK1 inhibitor with IC50 of 8.37μM.</p>Formule :C10H13N5ODegré de pureté :98.3%Couleur et forme :SolidMasse moléculaire :219.24TC-Mps1-12
CAS :<p>TC-Mps1-12 is an effective and selective inhibitor of monopolar spindle 1 (IC50: 6.4 nM) .</p>Formule :C17H20N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.38KP-23172
CAS :<p>KP-23172 is a inhibitor of PI3-K/Akt pathway.</p>Formule :C10H4N6ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :224.18Tau-aggregation and neuroinflammation-IN-1
CAS :<p>Potent tau aggregate inhibitor, anti-inflammatory, low cytotoxicity, reverses memory impairment in rats.</p>Formule :C25H20N2O7Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :460.44BCR-ABL-IN-7
CAS :<p>BCR-ABL-IN-7 is an inhibitor of ABL kinase activity in WT and T315I mutants.BCR-ABL-IN-7 can be used in chronic myeloid leukemia (CML) research.</p>Formule :C19H16FN3O3SDegré de pureté :98.28%Couleur et forme :SolidMasse moléculaire :385.41CpCDPK1/TgCDPK1-IN-1
CAS :<p>CpCDPK1/TgCDPK1-IN-1 is a inhibitor of CpCDPK1 and TgCDPK1, inhibits Abl and Src, and has antiparasitic activity for the study of Toxoplasma infections.</p>Formule :C18H17N5Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :303.36AM-5308
CAS :<p>AM-5308 is a kinesin KIF18A inhibitor that can be used to study cancer.</p>Formule :C26H35N5O5SDegré de pureté :98.06% - 99.58%Couleur et forme :SolidMasse moléculaire :529.65CGP60474
CAS :<p>CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC.</p>Formule :C18H18ClN5ODegré de pureté :98.81%Couleur et forme :SolidMasse moléculaire :355.82Pentachloropseudilin
CAS :<p>Pentachloropseudilin inhibits Myosin-1 and speeds up TGF-β receptor turnover, suppressing TGF-β activity.</p>Formule :C10H4Cl5NODegré de pureté :98.14%Couleur et forme :SolidMasse moléculaire :331.41Tyrphostin AG 568
CAS :<p>Tyrphostin AG 568 promotes Tyrphostin-induced inhibition of p210bcr-abl tyrosine kinase activity. It also induces K562 to differentiate.</p>Formule :C13H9N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :267.24DHNQ
CAS :<p>DHNQ is a novel inhibitor of the PI3K enzyme activity and transcriptional as well as translational expression levels in colorectal cancer (CRC).</p>Formule :C18H14N2OCouleur et forme :SolidMasse moléculaire :274.32NSC305787
CAS :<p>NSC305787 is an ezrin inhibitor with antitumor activity, inhibits ezrin phosphorylation caused by PKCΙ, and can be used in the study of pancreatic cancer.</p>Formule :C25H30Cl2N2ODegré de pureté :99.40%Couleur et forme :SolidMasse moléculaire :445.42Clathrin-IN-25
CAS :<p>Clathrin-IN-25 is the most effective clathrin terminal domain-amphiphysin inhibitor reported to date.</p>Formule :C19H13KNO5SCouleur et forme :SolidMasse moléculaire :406.47
