Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1382 produits trouvés pour "Signalisation du cytosquelette"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
BGB659
CAS :<p>BGB659 is effective inhibitor of RAF.</p>Formule :C29H29F3N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :538.56HR22C16
CAS :<p>HR22C16 is an effective, selective, and cell-permeable mitotic kinesin Eg5 inhibitor.</p>Formule :C23H23N3O3Couleur et forme :SolidMasse moléculaire :389.45DAT1
CAS :<p>DAT1 is an antimitotic and antiangiogenic that acts by binding to the colchicine binding site of tubulin.</p>Formule :C17H15N3O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.38Shz 1
CAS :<p>Shz 1 is a cardiogenic agent that induces phenotypic differentiation and various cardiac-specific genes including sarcomeric tropomyosin.</p>Formule :C13H11BrN2O3SDegré de pureté :99.57% - 99.91%Couleur et forme :SolidMasse moléculaire :355.21GSK-3008348
CAS :<p>GSK-3008348 is an antagonist of integrin alpha(v)beta6.</p>Formule :C29H37N5O2Degré de pureté :99.547%Couleur et forme :SolidMasse moléculaire :487.64NSC47924
CAS :<p>NSC47924 is a laminin receptor (LR) inhibitor.</p>Formule :C18H17NO2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :279.33ML-243
CAS :<p>inhibitor of cancer stem cells</p>Formule :C14H16N2OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :260.35Ro 43-5054
CAS :<p>Ro 43-5054 is a small molecular, noncyclic peptidomimetic inhibitor.</p>Formule :C24H27N5O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :497.5D011-2120
CAS :<p>D011-2120: Antiviral that blocks microtubule growth, disrupts Golgi, and hinders viral egress.</p>Formule :C17H15NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :281.31JG-48
CAS :<p>JG-48 is an inhibitor of Hsp70. JG-48 suppresses phosphorylated and total Tau in cells, endogenous Tau in neuroblastoma cells.</p>Formule :C20H16F3N3OS2Couleur et forme :SolidMasse moléculaire :435.49LDN-193665
CAS :<p>LDN-193665 is a potent inhibitor of tau kinase. It acts by targeting CDK5/p25 and GSK3β.</p>Formule :C15H11FN4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :314.34Diazobenzenesulfonic acid
CAS :<p>Diazobenzenesulfonic acid, white/red crystal, inhibits myosin ATPase 13 as an allosteric desensitizer.</p>Formule :C6H5N2O3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :185.18CCT036477
CAS :<p>CCT036477 selectively inhibits Wnt/β-catenin signaling, reducing TCF/LEF transcriptional activity.</p>Formule :C21H18ClN3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :347.84Acodazole hydrochloride
CAS :<p>Acodazole hydrochloride: synthetic imidazoquinoline with antineoplastic activity; disrupts DNA replication by intercalation.</p>Formule :C20H20ClN5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :381.86ABH Hydrochloride
CAS :<p>ABH Hydrochloride is an arginase inhibitor, it enhances both male and female sexual arousal responses.</p>Formule :C6H15BClNO4Couleur et forme :SolidMasse moléculaire :211.45Acodazole
CAS :<p>Acodazole is a synthetic imidazoquinoline. It has antimicrobial and antineoplastic properties. It also has been shown to treat arrhythmias.</p>Formule :C20H19N5ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :345.4L 703014
CAS :<p>L 703014 is an antagonist of the fibrinogen receptor.</p>Formule :C24H34N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :442.55Tubulin inhibitor 7
CAS :<p>Tubulin inhibitor 7 is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines (tubulin polymerization (IC50: 0.52 μM), K562 cell growth (</p>Formule :C21H14N2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :358.35PF-2771
CAS :<p>PF-2771: potent CENP-E inhibitor, IC50 of 16.1 nM, used in cancer treatment.</p>Formule :C29H36ClN5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :554.08Aha1/Hsp90-IN-1
CAS :<p>Aha1/Hsp90-IN-1 (Compound 17) inhibits Aha1/Hsp90, preventing tau aggregation; IC50 = 3.32 μM.</p>Formule :C22H17F3N4O2Couleur et forme :SolidMasse moléculaire :426.39OSIP-486823
CAS :<p>OSIP-486823（CP248） is a novel and potent microtubule disruptor with affinity for both protein kinase G (PKG) and microtubules.</p>Formule :C29H28FNO4Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :473.54NVS-PAK1-C
CAS :<p>NVS-PAK1-1: potent PAK1 inhibitor, IC50 5 nM (dephosphorylated), 6 nM (phosphorylated); ATP-competitive; weaker on PAK2 (IC50 270 nM, 720 nM).</p>Formule :C22H23ClF3N5OCouleur et forme :SoildMasse moléculaire :465.9EC 144
CAS :<p>EC 144, a second-generation selective inhibitor of Hsp90 , inhibits tumor growth for Hsp90α and degradation of Her-2 in MCF-7 cells.</p>Formule :C21H24ClN5O2Couleur et forme :SolidMasse moléculaire :413.9GF 15
CAS :<p>GF 15 is a potent inhibitor of centrosomal clustering in tumor cells.</p>Formule :C23H21ClO6Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.86CLT-28643
CAS :<p>CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.</p>Formule :C19H17N3O4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :351.36RUC-1
CAS :<p>RUC-1 is an αIIbβ3-selective ADP-induced platelet aggregation inhibitor.</p>Formule :C11H15N5OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :265.33NSC-668036
CAS :<p>NSC-668036 is an inhibitor of Dishevelled (Dvl) protein, a key protein in wnt signaling.</p>Formule :C21H36N2O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :460.52S-methyl DM1
CAS :<p>S-methyl DM1 is a thiomethyl derivative of Maytansine. S-methyl DM1 binds to tubulin(Kd of 0.93 μM) and inhibts microtubule polymerization.</p>Formule :C36H50ClN3O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :752.31AG-205
CAS :<p>(rac)-AG-205 inhibits Pgrmc1, affects sterol gene INSIG1, and hinder NF-kB/BDNF/PI3K/AKT in neuronal hypoxic resistance.</p>Formule :C22H23ClN6OSCouleur et forme :SolidMasse moléculaire :454.98ML-9 Free Base
CAS :<p>ML-9 suppresses MLCK, PKA, PKC (Ki: 4, 32, 54 μM), inhibits Akt kinase & STIM1, and induces autophagy.</p>Formule :C15H17ClN2O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :324.83Litronesib Racemate
CAS :<p>Litronesib is a selective, allosteric inhibitor of kinesin Eg5.Litronesib (Racemate) is the racemate of litronesib.</p>Formule :C23H37N5O4S2Couleur et forme :SolidMasse moléculaire :511.7TOK-8801
CAS :<p>TOK-8801 is a dihydroimidazole thiazole carboxamide with immunomodulatory activity.</p>Formule :C17H21N3OSDegré de pureté :99.97%Couleur et forme :SolidMasse moléculaire :315.43Creatine monohydrate
CAS :<p>Creatine monohydrate powers ATP for short, high-intensity activities in muscles and brain.</p>Formule :C4H11N3O3Degré de pureté :99.87%Couleur et forme :White SolidMasse moléculaire :149.15Amphethinile
CAS :<p>Amphethinile is an anti-tubulin agent. The Ka of Amphethinile with tubulin is 1.3 μM.</p>Formule :C15H11N3SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :265.33CCB02
CAS :<p>CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity.</p>Formule :C14H9N3ODegré de pureté :98.38%Couleur et forme :SolidMasse moléculaire :235.24Microtubule inhibitor 3
CAS :<p>Compounds 17o and 17p with furan have IC50s of 14.0 and 2.9 nM, respectively, against NCI-H460 cancer cells.</p>Formule :C26H23FN4O3Couleur et forme :SolidMasse moléculaire :458.48UR-3216
CAS :<p>UR-3216 is a prodrug, selectively antagonizing GPIIb/IIIa receptors orally, with its active form, UR-2992, binding tightly to platelets.</p>Formule :C27H29N7O7Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :563.56S516
CAS :<p>S516 is an active CKD-516 metabolite and is a potent inhibitor of tubulin polymerization(IC50 of 4.29 μM), has marked antitumor activity.</p>Formule :C21H19N5O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :437.47M435-1279
CAS :<p>M435-1279 is a UBE2T inhibitor. M435-1279 blocks UBE2T-mediated degradation of RACK1, leading to inhibit the hyperactivation of Wnt/β-catenin signaling pathway.</p>Formule :C18H17N3O5S2Degré de pureté :97.16%Couleur et forme :SolidMasse moléculaire :419.47QS11
CAS :<p>QS11, a GTPase ARFGAP1, modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation.</p>Formule :C36H33N5O2Degré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :567.68FAK inhibitor 2
CAS :<p>FAK inhibitor 2, antitumor and anti-angiogenesis activitiesis ,is a potent focal adhesion kinase (FAK) inhibitor with an IC50 of 0.07 nM .</p>Formule :C29H33F3N8O2S2Couleur et forme :SolidMasse moléculaire :646.75β-catenin-IN-3
CAS :<p>β-catenin-IN-3 is a selective and potent β-catenin inhibitor (KD: 54.96 nM) that targets a cryptic regulatory site of β-catenin and significantly reduces the</p>Formule :C19H20Br2N2OSCouleur et forme :SolidMasse moléculaire :484.252-Fluoropalmitic acid
CAS :<p>2-Fluoropalmitic acid, glioblastoma (GBM) by inhibiting the viability, proliferation, suppressing the expression of phosphorylated erk, CD133, and SOX-2, MMP-2.</p>Formule :C16H31FO2Couleur et forme :SolidMasse moléculaire :274.41Retaspimycin Hydrochloride
CAS :<p>Retaspimycin Hydrochloride is a potent and water-soluble Hsp90 inhibitor(Hsp90 and Grp9 with EC50s of 119 nM).</p>Formule :C31H46ClN3O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :624.17Anticancer agent 48
CAS :<p>Compound 48: broad-spectrum, anti-proliferative, inhibits microtubules, active in vivo, with potential for tumor research.</p>Formule :C26H25N3O4Couleur et forme :SolidMasse moléculaire :443.49MPC-3100
CAS :<p>MPC-3100 is an orally bioavailable, synthetic, second-generation small-molecule inhibitor of Hsp90 with significant antitumor activity [1].</p>Formule :C22H25BrN6O4SCouleur et forme :SolidMasse moléculaire :549.44Akt1 and Akt2-IN-1
CAS :<p>Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50=3.5 nM) and Akt2 (IC50=42 nM). It has potent and balanced activity.</p>Formule :C33H29N7OCouleur et forme :SolidMasse moléculaire :539.63Tubulin polymerization-IN-39
<p>Tubulin-IN-39 inhibits polymerization (IC50: 4.9 μM), blocks colchicine site, stops cancer growth.</p>Formule :C21H21N5O5Couleur et forme :SolidMasse moléculaire :423.42Integrin-IN-2
CAS :<p>Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.</p>Formule :C27H30N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.55Drp1-IN-1
CAS :<p>Drp1-IN-1 (comp A-7) is a Drp1 protein inhibitor (IC50: 0.91 μM).</p>Formule :C22H24N8OSCouleur et forme :SolidMasse moléculaire :448.54Microtubule inhibitor 1
CAS :<p>Microtubule inhibitor 1 is an antitumor agent with microtubule polymerization inhibitory activity(IC50 = 9-16 nM, in cancer cells).</p>Formule :C21H19NO3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :333.38Tubulin inhibitor 28
CAS :<p>Compound 2g, a tubulin inhibitor with an IC50 of 1.2 μM, inhibits MCF-7 cell proliferation.</p>Formule :C12H8Br2S2Couleur et forme :SolidMasse moléculaire :376.13ARUK3001185
CAS :<p>ARUK3001185 (8l): potent, selective Notum inhibitor; oral, brain-penetrant; IC50=6.7 nM; for rodent disease models.</p>Formule :C9H4Cl2F3N3Couleur et forme :SolidMasse moléculaire :282.05CHPG sodium salt
CAS :<p>CHPG sodium salt is a selective agonist of mGluR5 and activates the ERK and Akt signaling pathways.</p>Formule :C8H7ClNNaO3Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :223.59Valategrast
CAS :<p>Valategrast: potent, oral dual α4β1/α4β7 integrin antagonist, may treat COPD and asthma.</p>Formule :C30H32Cl3N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :604.95Cardionogen 1
CAS :<p>Wnt signaling modulator</p>Formule :C13H14N4OSDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :274.34EMD534085
CAS :<p>EMD534085 is an effective and selective mitotic kinesin-5 inhibitor (IC50: 8 nM).</p>Formule :C25H31F3N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :476.53Wnt/β-catenin agonist 1
CAS :<p>Wnt/β-catenin agonist 1 is an agonist of Wnt/β-catenin signalling pathway(EC50 of 0.27 μM).</p>Formule :C22H25N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :363.45BCR-ABL-IN-2
CAS :<p>BCR-ABL-IN-2 is a BCR-ABL1 tyrosine kinase inhibitor (IC50s: 57 nM, 773 nM for ABL1 native and ABL1 T315I).</p>Formule :C24H25Cl2N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :502.39Bimoclomol
CAS :<p>Bimoclomol is a heat shock protein co-inducer used for the research of cardiovascular diseases.</p>Formule :C14H20ClN3O2Couleur et forme :SolidMasse moléculaire :297.78UR-1505
CAS :<p>UR-1505 is an NF-AT inhibitor that prevents T cell activation without reducing cell viability.</p>Formule :C10H7F5O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :286.15c-ABL-IN-2
CAS :<p>C-ABL-IN-2 is a potent c-Abl protein inhibitor, promising for research in cancer and neurodegenerative diseases like ALS and PD.</p>Formule :C21H20N4OCouleur et forme :SolidMasse moléculaire :344.41AKT-IN-7
CAS :<p>AKT-IN-7 (compound 1-P1) is a potent inhibitor of AKT. AKT-IN-7 has potential for cancer research.</p>Formule :C23H27ClN6O2Couleur et forme :SolidMasse moléculaire :454.95YW1128
CAS :<p>YW1128 inhibits Wnt/β-catenin signaling (IC50=4.1 nM), reduces β-catenin, affects gene expression, and improves glucose tolerance and weight control in mice.</p>Formule :C20H17N5OCouleur et forme :SolidMasse moléculaire :343.38MT-7
CAS :<p>MT-7 is a tubulin polymerization inhibitor.</p>Formule :C22H17N3O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :355.39Kif15-IN-1
CAS :<p>Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.</p>Formule :C20H22N4O5SDegré de pureté :99.39% - 99.39%Couleur et forme :SolidMasse moléculaire :430.48Anticancer agent 49
CAS :<p>Anticancer agent 49, also 69, hinders cell growth and microtubule aggregation, with potential in solid and blood cancer research.</p>Formule :C26H25N3O4Couleur et forme :SolidMasse moléculaire :443.49Tubulin polymerization-IN-19
CAS :<p>Tubulin aggregation-IN-19 (compound 4) is a potent tubulin aggregation inhibitor that has shown potential in breast cancer and drug-resistant colon cancer.</p>Formule :C25H25NO5Couleur et forme :SolidMasse moléculaire :419.47HSP90-IN-12
CAS :<p>VAC, a potent anti-cancer vibsanin A analog, inhibits cell proliferation and affects HSP90 protein levels.</p>Formule :C25H36O4Couleur et forme :SolidMasse moléculaire :400.55DJ101
CAS :<p>DJ101: A stable tubulin inhibitor that bypasses multidrug resistance efflux pumps.</p>Formule :C23H20N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :400.43Hsp90-IN-15
CAS :<p>Hsp90-IN-15: Hsp90 blocker with anticancer properties; halts S phase, triggers apoptosis, cuts Hsp90 in Hela cells.</p>Formule :C23H27F3N4Couleur et forme :SolidMasse moléculaire :416.48YM-01 Tosylate
CAS :<p>YM-01 Tosylate, a potent antitumor agent, selectively targets cancer cells and overcoming tamoxifen resistance.</p>Formule :C27H27N3O4S3Couleur et forme :SolidMasse moléculaire :553.72Displurigen
CAS :<p>Displurigen is an inhibitor of ATPase activity of HSP70.</p>Formule :C15H10O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :286.3AKT-IN-9
CAS :<p>AKT-IN-9, a potent AKT inhibitor, may aid breast/prostate cancer studies. See WO2021185238A1.</p>Formule :C24H29ClN6OCouleur et forme :SolidMasse moléculaire :452.98ZW4864 free base
CAS :<p>ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor.</p>Formule :C33H42N6O3Degré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :570.72Box5
CAS :<p>Box5 blocks Wnt5a, reducing Ca2+ release and cell migration; promising for melanoma studies.</p>Formule :C30H50N6O13S2Couleur et forme :SolidMasse moléculaire :766.88Malonganenone A
CAS :<p>Malonganenone A is a selective plasmodial Hsp70s modulator. It also has antimalarial activity.</p>Formule :C26H38N4O2Couleur et forme :SolidMasse moléculaire :438.61Mivobulin
CAS :<p>Mivobulin is an inhibitor of tubulin .</p>Formule :C17H19N5O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :325.37NC043
CAS :<p>NC043 is an inhibitor of Wnt/β-catenin signaling, it forms a covalent bond with the Cys-516 residue of CARF.</p>Formule :C20H26O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :330.42KIF18A-IN-3
CAS :<p>KIF18A-IN-3 is a KIF18A inhibitor (IC50=61 nM) that causes significant mitotic arrest and increases the number of mitotic cells in tumor tissues.</p>Formule :C28H38N4O5S2Degré de pureté :98.45%Couleur et forme :SolidMasse moléculaire :574.76Zaurategrast ethyl ester
CAS :<p>Zaurategrast ethyl ester, an α4β1/α4β7 integrin antagonist prodrug of CT7758, treats inflammatory/autoimmune conditions.</p>Formule :C28H29BrN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :549.46IMB-10
CAS :<p>IMB-10 is an alphaMbeta2 integrin modulator, inhibiting leukocyte migration and recruitment in vitro and in vivo.</p>Formule :C19H15NOS2Couleur et forme :SolidMasse moléculaire :337.46(R)-Filanesib
CAS :<p>(R)-Filanesib is the R-enantiomer of ARRY-520. (R)-Filanesib is a synthetic kinesin spindle protein (KSP) inhibitor (IC50: 6 nM).</p>Formule :C20H22F2N4O2SCouleur et forme :SolidMasse moléculaire :420.48CH5138303
CAS :<p>CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.</p>Formule :C19H18ClN5O2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :415.9Tau protein aggregation-IN-1
CAS :<p>Tau Protein Aggregation-IN-1 (Compound 0c) serves as an inhibitor of Tau protein aggregation, applicable in research related to protein folding disorders</p>Formule :C17H11BrN2O2Couleur et forme :SolidMasse moléculaire :355.19CK2-IN-9
CAS :<p>CK2-IN-9, a potent and selective CK2 kinase inhibitor, exhibits an inhibitory concentration (IC50) of 3 nM against its target enzyme and hampers Wnt reporter</p>Formule :C23H29N9OCouleur et forme :SolidMasse moléculaire :447.54Zaurategrast ethyl ester sulfate
CAS :<p>Zaurategrast ethyl ester sulfate is a α4β1/α4β7 integrin antagonist, and used for the treatment of inflammatory and autoimmune disorders.</p>Formule :C56H60Br2N8O10SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1197.01Tubulin polymerization-IN-27
CAS :<p>Compound 5j inhibits tubulin polymerization, arrests cell cycle at G2/M phase, and induces apoptosis.</p>Formule :C22H20N2O2Couleur et forme :SolidMasse moléculaire :344.41CK548
CAS :<p>CK548 is a novel actin-related protein (Arp)2/3 complex inhibitor.</p>Formule :C15H11BrClNO2SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :384.68SC-10
CAS :<p>SC-10 is a direct activator of PKC with potential antiproliferative activity, useful in leukemia research.</p>Formule :C17H22ClNO2SDegré de pureté :99.24% - 99.58%Couleur et forme :SolidMasse moléculaire :339.88MG-2119
CAS :<p>MG-2119 is a potent inhibitor of monomeric tau and α-syn aggregation and can be used to study neurological diseases.</p>Formule :C27H29N5O4Couleur et forme :SolidMasse moléculaire :487.55AN-019
CAS :<p>AN-019 (NRC-019) is a Bcr-Abl kinase inhibitor with antitumor activity for the study of chronic myelogenous leukemia (CML) and breast cancer.</p>Formule :C25H17F6N5ODegré de pureté :98.99%Couleur et forme :SolidMasse moléculaire :517.43isoCA-4
CAS :<p>isoCA-4 is a Combretastatin A4 derivative. isoCA-4 is a tubulin polymerization inhibitor with anti-proliferative activities [1].</p>Formule :C18H20O5Couleur et forme :SolidMasse moléculaire :316.35Tubulin polymerization-IN-29
CAS :<p>Tubulin polymerization-IN-29 inhibits microtubule assembly, has anti-proliferative properties, and arrests HeLa cells at G2/M.</p>Formule :C25H20FNO6Couleur et forme :SolidMasse moléculaire :449.43BNC105P
CAS :<p>BNC105P, a prodrug VDA, converts to BNC105, blocks tubulin polymerization, disrupts tumor vessels, and evades P-glycoprotein resistance.</p>Formule :C20H21O10PCouleur et forme :SolidMasse moléculaire :452.34856BrCaQ
CAS :<p>6BrCaQ inhibits TRAP1, has antiproliferative effects, and is used in 6BrCaQ-TPP synthesis.</p>Formule :C18H15BrN2O3Couleur et forme :SolidMasse moléculaire :387.23Ellipticine quinone
CAS :<p>Ellipticine quinone (NSC-383230) outperforms mdivi-1 in inhibiting Drp1, reduces lung cancer growth, and lessens IR injury by curbing mitochondrial issues.</p>Formule :C15H8N2O2Couleur et forme :SolidMasse moléculaire :248.24Dynamin IN-1
CAS :<p>Dynamin IN-1 is a potent dynamin inhibitor with an IC 50 value of 1.0 µM .</p>Formule :C23H24N2OCouleur et forme :SolidMasse moléculaire :344.45PU3
CAS :<p>PU3 is an inhibitor of Hsp90.</p>Formule :C19H25N5O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :371.43Conteltinib
CAS :<p>Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK and Pyk2. It can be used to study lymphoma.</p>Formule :C32H45N9O3SDegré de pureté :98.12% - 99.54%Couleur et forme :SolidMasse moléculaire :635.82para-Nitroblebbistatin
CAS :<p>para-Nitroblebbistatin is a non-cytotoxic, non-fluorescent, photostable, and specific inhibitor of myosin II.Cost-effective and quality-assured.</p>Formule :C18H15N3O4Degré de pureté :99.09% - 99.84%Couleur et forme :SolidMasse moléculaire :337.33Rosabulin
CAS :<p>v Rosabulin (STA 5312) is an orally active microtubule inhibitor with potency.</p>Formule :C22H16N4O2SDegré de pureté :98.06%Couleur et forme :SolidMasse moléculaire :400.45JB062
CAS :<p>JB062 is a chemical compound acting as a nonmuscle myosin inhibitor, exhibiting IC50 values of 1.6, 5.4, and >100 μM against skeletal muscle myosin, cardiac</p>Formule :C19H17NO4Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :323.34Elarofiban
CAS :<p>Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.</p>Formule :C22H32N4O4Degré de pureté :98.76%Couleur et forme :SolidMasse moléculaire :416.51JB002
CAS :<p>JB002, a myosin II inhibitor, exhibits potent activity with an IC50 of ≤10 μM.</p>Formule :C18H15NO3Degré de pureté :99.74%Couleur et forme :SoildMasse moléculaire :293.32LY3372689
CAS :<p>LY3372689 (Formulaic Ia) is an orally active O-GlcNAcase (OGA) enzyme inhibitor for tau protein-based disorders including Alzheimer's disease.</p>Formule :C16H22FN5O3SDegré de pureté :99.43% - 99.53%Couleur et forme :SolidMasse moléculaire :383.44DCPLA-ME
CAS :<p>DCPLA-ME (2-[(2-Pentylcyclopropyl)methyl]cyclopropaneoctanoic acid methyl ester) is the methyl ester form of DCPLA and can be used to treat neurodegenerative</p>Formule :C21H38O2Degré de pureté :99.80%Couleur et forme :SolidMasse moléculaire :322.53CID-663143
CAS :<p>CID-663143 inhibits cancer cell growth and shows microtubule-binding activity.</p>Formule :C19H18N4O2SDegré de pureté :99.68% - 99.77%Couleur et forme :SolidMasse moléculaire :366.44BIRT-377
CAS :<p>BIRT-377: orally active, hinders ICAM-1/LFA-1, blocks IL-2, useful for immune research. (Ki=25.8 nM).</p>Formule :C18H15BrCl2N2O2Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :442.13Nilotinib hydrochloride
CAS :<p>Nilotinib HCl (AMN-107 HCl), an oral Bcr-Abl inhibitor, targets neuroinflammation, cognitive issues, and chronic myelogenous leukemia.</p>Formule :C28H23ClF3N7ODegré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :565.98TCS 2210
CAS :<p>TCS 2210 promotes neuronal differentiation in stem cells, boosting β-III tubulin and enolase markers.</p>Formule :C18H17N3O3Degré de pureté :98.62%Couleur et forme :SolidMasse moléculaire :323.35SB-216
CAS :<p>SB-216, a potent anti-cancer compound, inhibits tubulin polymerization and curbs growth in various cancer cells.</p>Formule :C17H18N4O2Degré de pureté :99.70%Couleur et forme :SolidMasse moléculaire :310.35AMP-PCP disodium
CAS :<p>AMP-PCP disodium is an ATP analogue with binding affinity to the N-terminal domain of Hsp90, with a Kd value of 3.8 μM.</p>Formule :C11H16N5Na2O12P3Degré de pureté :99.32%Couleur et forme :SolidMasse moléculaire :549.17BMD4503-2
CAS :<p>BMD4503-2 is a competitive inhibitor of the LRP5/6-sclerostin complex that restores the activity of the Wnt/β-catenin signaling pathway cancer.</p>Formule :C26H21N5O3SDegré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :483.54JB061
<p>JB061 is a nonmuscle myosin inhibitor, demonstrating selective inhibitory activity with IC50 values of 4.4 μM (Cardiac muscle myosin), 9.1 μM (Skeletal muscle</p>Formule :C19H17NO4Degré de pureté :99.67%Couleur et forme :SoildMasse moléculaire :323.34NSC668394
CAS :<p>NSC668394 is an ezrin phosphorylation inhibitor.NSC668394 has antitumor activity and increases ezrin cleavage.NSC668394 can be used to study tumor metastasis.</p>Formule :C17H12Br2N2O3Degré de pureté :99.29% - 99.29%Couleur et forme :SolidMasse moléculaire :452.1CMPF
CAS :<p>CMPF is a microtubule protein inhibitor that can be used to study tumors.</p>Formule :C12H16O5Degré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :240.25AZ13705339
CAS :<p>AZ13705339 is an effective inhibitor of PAK1 with an IC50 of 0.33 nM and a Kd of 0.28 nM.</p>Formule :C33H36FN7O3SDegré de pureté :99.77%Couleur et forme :SolidMasse moléculaire :629.75DZ2002
CAS :<p>DZ2002: Oral, reversible SAHH inhibitor (Ki=17.9 nM), low-toxicity, immunosuppressive, counters dermal fibrosis, used in autoimmune research.</p>Formule :C10H13N5O3Degré de pureté :99.91%Couleur et forme :SolidMasse moléculaire :251.24JH-VIII-157-02
CAS :<p>JH-VIII-157-02 inhibits ALK, specifically EML4-ALK variants, with IC50s of 2 nM.</p>Formule :C28H27N5O2Degré de pureté :99.58%Couleur et forme :SolidMasse moléculaire :465.55Arimoclomol
CAS :<p>Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (</p>Formule :C14H20ClN3O3Degré de pureté :99.15%Couleur et forme :SolidMasse moléculaire :313.78ZINC00640089
CAS :<p>ZINC00640089: Selective LCN2 inhibitor; curbs SUM149 cell growth and AKT activity; useful for IBC research.</p>Formule :C20H13F3N2O2Degré de pureté :98.41% - 99.80%Couleur et forme :SolidMasse moléculaire :370.32DM1-SMe
CAS :<p>DM1-SMe (DM1-SSMe) potently inhibits microtubules, 3-10x stronger than Maytansine with IC50s of 0.003-0.01 nM in human cancer cells.</p>Formule :C36H50ClN3O10S2Degré de pureté :99.61%Couleur et forme :SolidMasse moléculaire :784.38Defactinib hydrochloride
CAS :<p>Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK.</p>Formule :C20H22ClF3N8O3SDegré de pureté :98.06% - 98.78%Couleur et forme :SolidMasse moléculaire :546.95PPY A
CAS :<p>PPY A is a potent inhibitor of T315l mutant and wild-type Abl kinase and inhibits the growth of Bcr-Abl T315l mutant or wild-type Bcr-Abl gene-transformed cells</p>Formule :C22H20N4O2Degré de pureté :98.77%Couleur et forme :SolidMasse moléculaire :372.42Iroxanadine
CAS :<p>Iroxanadine (BRX-005) is a Novel small molecule MAPK p38 inhibitor that induces phosphorylation of p38 SAPK and induces concentration-dependent relaxation in</p>Formule :C14H20N4ODegré de pureté :98.04% - 99.04%Couleur et forme :SolidMasse moléculaire :260.33Tubulin inhibitor 8
CAS :<p>Tubulin inhibitor 8 blocks tubulin polymerization, stunts K562 cancer cell growth; IC50: 0.73 μM, 14 nM.</p>Formule :C21H14N2O3Degré de pureté :98.51% - 99.87%Couleur et forme :SolidMasse moléculaire :342.35Elsibucol
CAS :<p>Elsibucol (AGI 1096) is a VCAM1 inhibitor for the study of organ transplant rejection.Elsibucol is a metabolically stable propanol derivative with antioxidant,</p>Formule :C35H54O4S2Degré de pureté :99.73%Couleur et forme :SolidMasse moléculaire :602.93AKT-IN-6
CAS :<p>AKT-IN-6 (INCB-047775) inhibits Akt, a key signaling protein linked to type 2 diabetes and cancer.</p>Formule :C22H20FN5ODegré de pureté :98.68%Couleur et forme :SolidMasse moléculaire :389.43Terflavoxate
CAS :<p>Terflavoxate is a novel, orally active, semisynthetic statin microtubule inhibitor commonly used in combination with capecitabine.</p>Formule :C26H29NO4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :419.51Firategrast
CAS :<p>Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous</p>Formule :C27H27F2NO6Degré de pureté :99.16%Couleur et forme :SolidMasse moléculaire :499.5SNX0723
CAS :<p>SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity.</p>Formule :C22H26FN3O3Degré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :399.46Erbulozole
CAS :<p>Erbulozole (R 55104) is a synthetic microtubule inhibitor with anti-invasive activity that induces Wernicke's encephalopathy-like neurotoxicity.</p>Formule :C24H27N3O5SDegré de pureté :99.88%Couleur et forme :SolidMasse moléculaire :469.55Bis-T-23
CAS :<p>Bis-T-23 is a promoter of actin-dependent dynamin oligomerization, an HIV-I integrase inhibitor, and a Telstar derivative.</p>Formule :C23H20N4O8Degré de pureté :96.81% - 98.13%Couleur et forme :SolidMasse moléculaire :480.43Dynapyrazole A
CAS :<p>Dynapyrazole A inhibits dynein 1 and 2 (IC50s: 2.3, 2.6 μM) and Hedgehog signaling (IC50: 1.9 μM).</p>Formule :C20H12ClIN4ODegré de pureté :98.01%Couleur et forme :SolidMasse moléculaire :486.69UMK57
CAS :<p>UMK57 is a CENP-Ei and MCAK enhancer, selectively promoting k-MT attachment error correction to inhibit chromosome missegregation of small molecule compounds,</p>Formule :C17H17N3SDegré de pureté :99.81%Couleur et forme :SolidMasse moléculaire :295.4EMT inhibitor-1
CAS :<p>EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity.</p>Formule :C12H12Cl2N2O2SDegré de pureté :99.53%Couleur et forme :SolidMasse moléculaire :319.21JG-231
CAS :<p>JG-231, a JG-98 analog, shows anticancer properties by blocking Hsp70-BAG3 interaction and hindering TNBC in MDA-MB-231 models.</p>Formule :C22H18BrCl2N3OS4Degré de pureté :99.79%Couleur et forme :SolidMasse moléculaire :619.47ASN90
CAS :<p>ASN90 is a specific, orally active inhibitor of the O-GlcNAcase (OGA) enzyme, demonstrating an IC50 of 10.2 nM.</p>Formule :C17H21N5O3SCouleur et forme :SolidMasse moléculaire :375.45AKT-IN-13
CAS :<p>AKT-IN-13 inhibits Akt1, Akt2, Akt3 (IC50: 1.6, 2.4, 0.3 nM); used in cancer research.</p>Formule :C24H31ClN6O2Couleur et forme :SolidMasse moléculaire :470.99ICAM-1-IN-1
CAS :<p>ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.</p>Formule :C15H11BrN2O2SDegré de pureté :99.67%Couleur et forme :SolidMasse moléculaire :363.23ATN-161
CAS :<p>ATN-161 is an integrin α5β1 binding peptide and antagonist that inhibits VEGF-induced hCECs migration and angiogenesis.</p>Formule :C23H35N9O8SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :597.64MAO A/HSP90-IN-2
CAS :<p>MAO A/HSP90-IN-2 (compound 4-C), a dual inhibitor of HSP90 and MAO A, exhibits IC50 values of 0.016 μM for MAO A and 4.58 μM for HSP90.</p>Formule :C25H31ClN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :458.98VTX-27
CAS :<p>VTX-27 is a selective inhibitor of protein kinase C θ (PKC θ) (Kis: 0.08 nM and 16 nM for PKC θ and PKC δ).</p>Formule :C20H24ClFN6ODegré de pureté :99.84%Couleur et forme :SolidMasse moléculaire :418.9WAY 316606 hydrochloride
CAS :<p>WAY 316606 hydrochloride is a chemical compound that serves as an inhibitor of sFRP-1 (secreted protein), which functions as an endogenous antagonist of the Wnt (secreted glycoprotein). Its affinity for sFRP-1 is measured through the FP (fluorescence polarization) binding assay, revealing an IC50 (half maximal inhibitory concentration) of 0.5 μM [1].</p>Formule :C18H20ClF3N2O4S2Couleur et forme :SolidMasse moléculaire :484.94CCT251455
CAS :<p>CCT251455, the mitotic kinase monopolar spindle 1 (MPS1/TTK) inhibitor, is a potent (IC50=3 nM) and specific chemical tool.</p>Formule :C26H26ClN7O2Degré de pureté :99.1% - 99.1%Couleur et forme :SolidMasse moléculaire :503.98TAK 029
CAS :<p>TAK 029 is a local glycoprotein IIb/IIIa receptor inhibitor.</p>Formule :C19H23N5O7Couleur et forme :SolidMasse moléculaire :433.42JG-23
CAS :<p>JG-23, a 4-chloro-modified analog, effectively induces t-tau degradation and demonstrates robust metabolic stability, exhibiting an extended half-life (T1/2) of</p>Formule :C19H16ClN3OS2Couleur et forme :SolidMasse moléculaire :401.93Tubulin polymerization-IN-52
CAS :<p>Tubulin polymerization-IN-52 (compound SC23) effectively inhibits tubulin polymerization, exhibiting an IC50 value of 2.9 μM [1].</p>Formule :C21H18F3N5O3Couleur et forme :SolidMasse moléculaire :445.39Oxaline
CAS :<p>Oxaline, a fungal alkaloid derived from Penicillium oxalicum, impedes tubulin polymerization, leading to cell cycle arrest at the M phase [1] [2].</p>Formule :C24H25N5O4Couleur et forme :SolidMasse moléculaire :447.49MC-Val-Cit-PAB-Ispinesib
CAS :<p>MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent Eg5 inhibitor and a click chemistry reagent [1].</p>Formule :C59H71ClN10O10Couleur et forme :SolidMasse moléculaire :1115.71β-Catenin modulator-2
CAS :<p>β-Catenin Modulator-2 (Compound IIa-130), which is an oxazole-thiazole derivative, serves as a potent and selective modulator of β-Catenin [1].</p>Formule :C20H18Cl2N2O3SCouleur et forme :SolidMasse moléculaire :437.34CNS-11
CAS :<p>CNS-11, a compound that disaggregates tau fibrils, is utilized in Alzheimer's disease (AD) research [1].</p>Formule :C25H21N3O2Couleur et forme :SolidMasse moléculaire :395.45PTK7/β-catenin-IN-1
CAS :<p>PTK7/β-catenin-IN-1 (compound 01065) is a potent inhibitor targeting PTK7/β-catenin and p53/MDM2, with IC50 values of 8.9 μM and 56.5 μM, respectively. This compound shows promise for cancer research applications [1].</p>Formule :C22H16N2O2Couleur et forme :SolidMasse moléculaire :340.382BI-1950
CAS :<p>BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.</p>Formule :C32H26Cl2FN7O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :646.5BX-2819
CAS :<p>BX-2819 is an Hsp90 inhibitor that exhibits potent antiproliferative activity with an IC50 of 41 nM .</p>Formule :C21H24N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.51UU-T01
CAS :<p>UU-T01 inhibits β-catenin/Tcf4 with Ki of 3.14 µM, binds β-catenin directly with KD of 0.531 µM.</p>Formule :C10H10N6OCouleur et forme :SolidMasse moléculaire :230.23Teclistamab
CAS :<p>Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.</p>Degré de pureté :95%Couleur et forme :Liquidβ-Catenin modulator-5
CAS :<p>β-Catenin Modulator-5 (Compound IIa-84), an oxazole and thiazole-based compound, serves as a potent and selective modulator of β-Catenin [1].</p>Formule :C21H22N2O2SCouleur et forme :SolidMasse moléculaire :366.48Flavokawain 1i
CAS :<p>Flavokawain 1i, a derivative of chalcones flavokawain A, flavokawain B, and flavokawain C, exhibits anticancer and antiviral properties.</p>Formule :C21H18O4Couleur et forme :SolidMasse moléculaire :334.37AKT-I-1
CAS :<p>AKT-I-1 is a selective and reversible inhibitor of Akt1.</p>Formule :C22H30N6Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :378.51G-5555
CAS :<p>G-5555 is a potent inhibitor of p21-activated kinase 1 (PAK1) (Kis: 3.7 nM and 11 nM for PAK1 and PAK2, respectively).</p>Formule :C25H25ClN6O3Degré de pureté :99.76% - 99.84%Couleur et forme :SolidMasse moléculaire :492.96β-Catenin modulator-1
CAS :<p>β-Catenin modulator-1 (IIa-650) is a useful agent in cancer research for modulating β-Catenin [1].</p>Formule :C21H28N2O4SCouleur et forme :SolidMasse moléculaire :404.52JNJ-26076713
CAS :<p>JNJ-26076713, an oral alpha V integrin blocker, may treat macular edema, AMD, and diabetic retinopathy.</p>Formule :C29H38N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.64β-Catenin modulator-4
CAS :<p>β-Catenin modulator-4 (compound IIa-92), encompassing oxazole and thiazole moieties, acts as a potent and selective modulator of β-Catenin [1].</p>Formule :C21H21ClN2O2SCouleur et forme :SolidMasse moléculaire :400.92Luvixasertib hydrochloride
CAS :<p>CFI-402257 hydrochloride, a highly selective and orally bioavailable inhibitor targeting TTK/Mps1, demonstrates an in vitro IC50 value of 1.7 nM against TTK. This compound exhibits anti-cancer activity [1].</p>Formule :C28H31ClN6O3Couleur et forme :SolidMasse moléculaire :535.04TAS0612
CAS :<p>TAS0612, a novel oral inhibitor of RSK, AKT, and S6K, exhibits broad-spectrum antitumor activity by impeding cell growth [1].</p>Formule :C27H34F3N9O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :573.61PAK1-IN-1
CAS :<p>PAK1-IN-1: PAK1 inhibitor, IC50 9.8 nM, hinders tumor cell migration and invasion dose-dependently.</p>Formule :C26H20ClN5O2Couleur et forme :SolidMasse moléculaire :469.92Pivanex
CAS :<p>Pivanex, an oral HDAC inhibitor, targets metastasis, angiogenesis, reduces Bcr-Abl protein, and promotes apoptosis.</p>Formule :C10H18O4Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :202.25ALM301
CAS :<p>ALM301: oral AKT inhibitor targeting AKT1, AKT2, AKT3; blocks AKT phosphorylation, curbs cancer cell growth.</p>Formule :C25H25N3O3Couleur et forme :SolidMasse moléculaire :415.48Dolastatinol
CAS :<p>Dolastatinol, a synthetic analog of Dolastatin 10, serves as a potent low-nanomolar inhibitor of tubulin polymerization.</p>Formule :C43H70N6O7SCouleur et forme :SolidMasse moléculaire :815.12αvβ1 integrin-IN-2
CAS :<p>αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.</p>Formule :C29H38N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.64SB-267268
CAS :<p>SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).</p>Formule :C22H24F3N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.44Valecobulin hydrochloride
CAS :<p>Valecobulin hydrochloride (CKD-516 hydrochloride) is the valine prodrug and vasoblocker of S516.Cost-effective and quality-assured.</p>Formule :C26H29ClN6O5SDegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :573.06CCT-271850
CAS :<p>CCT-271850 is an inhibitor of the spindle checkpoint function of Monospindle 1.</p>Formule :C24H29N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :431.53Paluratide
CAS :<p>Paluratide (LUNA18) is a reversible KRAS inhibitor oral , which inhibits cancer cell proliferation by phosphorylating ERK and AKT, RAS with (GEFs).</p>Formule :C73H105F5N12O12Degré de pureté :98.70%Couleur et forme :SolidMasse moléculaire :1437.68Levocabastine
CAS :<p>Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.</p>Formule :C26H29FN2O2Couleur et forme :SolidMasse moléculaire :420.52ER degrader 7
CAS :<p>ER degrader 7 (Compound 35t) is a selective degrader of both ERα and ERβ, and possesses activity as a tubulin polymerization inhibitor.</p>Formule :C33H31F4N3O5SSeCouleur et forme :SolidMasse moléculaire :736.63Zaurategrast
CAS :<p>Zaurategrast is an effective and oral-effective inhibitor of the α4-integrin.</p>Formule :C26H25BrN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :521.41Phenamacril
CAS :<p>Phenamacril (JS39919) is acyanoacrylate fungicide, has powerful inhibition against Fusarium species, especially to Fusarium graminearum.</p>Formule :C12H12N2O2Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :216.24HSP90-IN-29
CAS :<p>HSP90-IN-29 (Compound 13), a benzoxazole derivative, serves as a potent and selective HSP-90 inhibitor, exhibiting a low IC50 value of 30 nM. This compound demonstrates significant antitumor activity [1].</p>Formule :C19H20ClN3O4Couleur et forme :SolidMasse moléculaire :389.83Akt-I-1,2
CAS :<p>Akt-I-1,2 is a selective inhibitor of Akt1 and Akt2.</p>Formule :C23H22ClN3Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :375.893,4',5-Trismethoxybenzophenone
CAS :<p>3,4',5-Trismethoxybenzophenone (compound 16a) is an effective inhibitor of tubulin assembly, demonstrating a half-maximal inhibitory concentration (IC 50) of 2.6 µM [1].</p>Formule :C16H16O4Couleur et forme :SolidMasse moléculaire :272.3GRP78-IN-2
CAS :<p>GRP78-IN-2 inhibits surface GRP78, showing anti-angiogenic and anti-cancer properties, sparing normal cells.</p>Formule :C29H29NO6Couleur et forme :SolidMasse moléculaire :487.54Tirofiban HCl
CAS :<p>Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.</p>Formule :C22H37ClN2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.06Iroxanadine sulfate
CAS :<p>Iroxanadine sulfate is a MAPK p38 inhibitor potentially for the treatment of atherosclerosis.</p>Formule :C14H22N4O5SCouleur et forme :SolidMasse moléculaire :358.41Integrin Antagonists 27
CAS :<p>Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.</p>Formule :C24H20N4O5Couleur et forme :SolidMasse moléculaire :444.44PAK4-IN-1
CAS :<p>PAK4-IN-1: selective, potent oral PAK4 inhibitor; stable in acid/neutral; shows strong anti-tumor in vivo.</p>Formule :C26H30ClN7O5Couleur et forme :SolidMasse moléculaire :556.01Porcn-IN-2
CAS :<p>Porcn-IN-2 (Example 107) is a potent Wnt pathway inhibitor, exhibiting an IC50 of 0.05 nM.</p>Formule :C24H17F3N6OCouleur et forme :SolidMasse moléculaire :462.43αvβ6 integrin inhibitor 2
CAS :<p>αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.</p>Formule :C21H30N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :386.49Risvodetinib
CAS :<p>Risvodetinib: potent inhibitor of protein tyrosine kinases c-Abl1, c-Abl2, and c-kit.</p>Formule :C33H34N8O2Couleur et forme :SolidMasse moléculaire :574.68Solitomab
CAS :<p>Solitomab (AMG 110) is a bispecific antibody targeting CD3 and EpCAM, used in uterine/ovarian carcinosarcoma research.</p>Couleur et forme :LiquidLitronesib
CAS :<p>Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.</p>Formule :C23H37N5O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.7Tubulin inhibitor 25
CAS :<p>Potent Tubulin inhibitor 25: IC50 0.98 μM, blocks HT29 cell growth, hinders cell migration & microtubule formation, anti-angiogenic.</p>Formule :C26H22O8Couleur et forme :SolidMasse moléculaire :462.45β-catenin-IN-6
CAS :<p>β-Catenin-IN-6 is an inhibitor of the canonical Wnt/β-catenin signaling pathway, effectively impeding the proliferation of human colorectal cancer cells and</p>Formule :C22H19ClN6OCouleur et forme :SolidMasse moléculaire :418.88KIF18A-IN-7
CAS :<p>KIF18A-IN-7 is an orally active inhibitor targeting KIF18A, demonstrating potent inhibition with an IC50 value of 9.4 nM against the microtubule-dependent</p>Formule :C27H35N3O5S2Couleur et forme :SoildMasse moléculaire :545.71MAO A/HSP90-IN-1
CAS :<p>MAO A/HSP90-IN-1 (4-b) is a dual inhibitor of MAO A and HSP90, exhibiting IC50 values of 1.77 μM in glioblastoma (GBM) GL26 cells and 0.019 μM against HSP90α.</p>Formule :C24H29ClN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.95LY2780301
CAS :<p>LY2780301, an oral Akt (protein kinase B) inhibitor, may hinder cancer cell growth and trigger apoptosis by blocking the PI3K/Akt pathway.</p>Formule :C25H27F4N7OCouleur et forme :SolidMasse moléculaire :517.52KSP-IA
CAS :<p>KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.</p>Formule :C21H22F2N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.41Lotrafiban hydrochloride
CAS :<p>Lotrafiban hydrochloride is an platelet glycoprotein IIb/IIIa blocker with oral activity.</p>Formule :C23H33ClN4O4Couleur et forme :SolidMasse moléculaire :464.99
