Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1382 produits trouvés pour "Signalisation du cytosquelette"
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Sovilnesib
CAS :<p>Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.</p>Formule :C26H34F2N6O4SDegré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :564.65Ispinesib
CAS :<p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>Formule :C30H33ClN4O2Degré de pureté :98% - 99.09%Couleur et forme :SolidMasse moléculaire :517.06Gap 26
CAS :<p>Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.</p>Formule :C70H107N19O19SDegré de pureté :98.26%Couleur et forme :SolidMasse moléculaire :1550.78Dasatinib N-oxide
CAS :<p>Dasatinib N-oxide is a key metabolite and potential impurity of the kinase inhibitor dasatinib.</p>Formule :C22H26ClN7O3SDegré de pureté :98.54% - 99.94%Couleur et forme :SolidMasse moléculaire :504PF04929113
CAS :<p>PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.</p>Formule :C25H30F3N5O4Degré de pureté :99.04%Couleur et forme :SolidMasse moléculaire :521.53XL888
CAS :<p>XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.</p>Formule :C29H37N5O3Degré de pureté :99.18%Couleur et forme :SolidMasse moléculaire :503.64HM03 trihydrochloride
CAS :<p>HM03 trihydrochloride is a potent and selective inhibitor of HSPA5, also known as Bip or Grp78. It exhibits anticancer activity.</p>Formule :C26H30Cl4N4O2Couleur et forme :SolidMasse moléculaire :572.35H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS :<p>RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.</p>Formule :C23H38N10O10Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :614.61PKC ζ pseudosubstrate acetate
<p>PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide.</p>Formule :C78H132N30O18Degré de pureté :98.78%Couleur et forme :SolidMasse moléculaire :1778.10ILK-IN-2
CAS :<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Formule :C30H30F3N5ODegré de pureté :99.30%Couleur et forme :SolidMasse moléculaire :533.59CWHM-12
CAS :<p>CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).</p>Formule :C26H32BrN5O6Degré de pureté :98.05% - 99.83%Couleur et forme :SolidMasse moléculaire :590.47Degrasyn
CAS :<p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>Formule :C19H18BrN3ODegré de pureté :98.32% - 99.98%Couleur et forme :SolidMasse moléculaire :384.27AT9283
CAS :<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Formule :C19H23N7O2Degré de pureté :99.83% - 99.98%Couleur et forme :SolidMasse moléculaire :381.43Cyclo(-RGDfK) TFA
CAS :<p>Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).</p>Formule :C29H42F3N9O9Degré de pureté :98.99% - 99.54%Couleur et forme :SolidMasse moléculaire :717.69Doxepin
CAS :<p>Doxepin: tricyclic antidepressant, inhibits serotonin/norepinephrine reuptake, helps atopic dermatitis/urticaria, cognitive protector, anti-inflammatory.</p>Formule :C19H21NOCouleur et forme :SolidMasse moléculaire :279.38[Ala113]-MBP (104-118) acetate
<p>[Ala113]MBP(104-118) acetate is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 28-62 μM.</p>Formule :C69H108N20O21Degré de pureté :97.72%Couleur et forme :SolidMasse moléculaire :1553.74Fingolimod
CAS :<p>Fingolimod (FTY-720A) is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).</p>Formule :C19H33NO2Degré de pureté :99.53% - 99.6%Couleur et forme :SolidMasse moléculaire :307.47Mps1-IN-1 dihydrochloride
CAS :<p>Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM.</p>Formule :C28H35Cl2N5O4SCouleur et forme :SolidMasse moléculaire :608.58Aficamten
CAS :<p>Aficamten is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy.</p>Formule :C18H19N5O2Degré de pureté :99.19% - 99.57%Couleur et forme :SolidMasse moléculaire :337.38MMAD
CAS :<p>MMAD (Demethyldolastatin 10) is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs).</p>Formule :C41H66N6O6SDegré de pureté :99.25% - 99.91%Couleur et forme :SolidMasse moléculaire :771.06CK-869
CAS :<p>CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools for the investigation of the Arp2/3 complex.</p>Formule :C17H16BrNO3SDegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :394.28Imatinib
CAS :<p>Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kit</p>Formule :C29H31N7ODegré de pureté :99.42% - 99.94%Couleur et forme :Off White PowderMasse moléculaire :493.6PIR 3.5
CAS :<p>PIR 3.5 (6,6′-Dithiodi(2-naphthol)) is a negative control of IPA 3 which is a Pak1 inhibitor.</p>Formule :C20H14O2S2Degré de pureté :98.08%Couleur et forme :SolidMasse moléculaire :350.45Staurosporine
CAS :<p>Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr</p>Formule :C28H26N4O3Degré de pureté :99.24% - 99.82%Couleur et forme :Off-White PowderMasse moléculaire :466.53XL228
CAS :<p>XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).</p>Formule :C22H31N9ODegré de pureté :99.07%Couleur et forme :SolidMasse moléculaire :437.54MitoBloCK-10
CAS :<p>MitoBloCK-10 inhibits Tim44-Hsp70 binding; first to reduce PAM complex activity.</p>Formule :C12H8FN3O3SDegré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :293.27TR-14035
CAS :<p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>Formule :C24H21Cl2NO5Degré de pureté :98.98%Couleur et forme :SolidMasse moléculaire :474.33Flumatinib
CAS :<p>Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.</p>Formule :C29H29F3N8ODegré de pureté :99.39% - 99.95%Couleur et forme :SolidMasse moléculaire :562.59OSU-T315
CAS :<p>OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.</p>Formule :C30H30F3N5ODegré de pureté :98.69%Couleur et forme :SolidMasse moléculaire :533.59Onalespib
CAS :<p>Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.</p>Formule :C24H31N3O3Degré de pureté :98.05% - 99.66%Couleur et forme :SolidMasse moléculaire :409.52TPPB
CAS :<p>TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).</p>Formule :C27H30F3N3O3Degré de pureté :97.71% - 98.00%Couleur et forme :SolidMasse moléculaire :501.54Triciribine
CAS :<p>Triciribine (NSC-154020) is a DNA synthesis inhibitor, and it also inhibits Akt and HIV-1/2.</p>Formule :C13H16N6O4Degré de pureté :99.01% - 99.87%Couleur et forme :SolidMasse moléculaire :320.3Tirbanibulin
CAS :<p>Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.</p>Formule :C26H29N3O3Degré de pureté :99.43% - 99.67%Couleur et forme :SolidMasse moléculaire :431.53Albendazole sulfoxide
CAS :<p>Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.</p>Formule :C12H15N3O3SDegré de pureté :97.29%Couleur et forme :White To Off-White PowderMasse moléculaire :281.33Ro 31-8220 Mesylate
CAS :<p>Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.</p>Formule :C25H23N5O2S·CH4O3SDegré de pureté :98.79% - 99.02%Couleur et forme :SolidMasse moléculaire :553.65Flumatinib mesylate
CAS :<p>Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.</p>Formule :C30H33F3N8O4SDegré de pureté :99.82%Couleur et forme :SolidMasse moléculaire :658.69D-64131
CAS :<p>D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.</p>Formule :C16H13NO2Degré de pureté :99.48% - 99.67%Couleur et forme :SolidMasse moléculaire :251.28KBU2046
CAS :<p>KBU2046: oral anti-metastasis compound, enhances survival, targets chaperone complexes, not a typical HSP90 inhibitor.</p>Formule :C15H11FO2Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :242.24Procyanidin A1
CAS :<p>Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+.</p>Formule :C30H24O12Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :576.5HSP27 inhibitor J2
CAS :<p>HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of</p>Formule :C13H12O4SDegré de pureté :99.51%Couleur et forme :SolidMasse moléculaire :264.3GMB-475
CAS :<p>GMB-475, a PROTAC-based BCR-ABL1 inhibitor, tackles drug resistance by promoting VHL-mediated degradation.</p>Formule :C43H46F3N7O7SDegré de pureté :98.78% - >99.99%Couleur et forme :SolidMasse moléculaire :861.93Dynasore
CAS :<p>Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.</p>Formule :C18H14N2O4Degré de pureté :95.85% - 99.22%Couleur et forme :SolidMasse moléculaire :322.31NRX-252262
CAS :<p>NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50：3.8 nM)</p>Formule :C23H17Cl2F3N2O4SDegré de pureté :98.94% - 99.87%Couleur et forme :SolidMasse moléculaire :545.36Borussertib
CAS :<p>Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt(IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt)</p>Formule :C36H32N6O3Degré de pureté :99.00%Couleur et forme :SolidMasse moléculaire :596.68Ingenol
CAS :<p>Ingenol mebutate treats actinic keratosis, has anticancer properties, and may reactivate latent HIV.</p>Formule :C20H28O5Degré de pureté :99.78% - 99.87%Couleur et forme :SolidMasse moléculaire :348.43BX517
CAS :<p>BX517 (PDK1 inhibitor 2) is a potent and selective inhibitor of PDK1.</p>Formule :C15H14N4O2Degré de pureté :99.26%Couleur et forme :SolidMasse moléculaire :282.32-hydroxy Flutamide
CAS :<p>2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer</p>Formule :C11H11F3N2O4Degré de pureté :99.45% - 99.82%Couleur et forme :SolidMasse moléculaire :292.21Sotrastaurin
CAS :<p>Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).</p>Formule :C25H22N6O2Degré de pureté :98% - 99.70%Couleur et forme :SolidMasse moléculaire :438.48PF-431396
CAS :<p>PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).</p>Formule :C22H21F3N6O3SDegré de pureté :98.83% - 99.82%Couleur et forme :SolidMasse moléculaire :506.5Decursinol angelate
CAS :<p>Decursinol angelate is anti-tumor, anti-inflammatory, anti-oxidant, hepatoprotective, and inhibits VEGF and cancer cell invasion.</p>Formule :C19H20O5Degré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :328.36
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