Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1382 produits trouvés pour "Signalisation du cytosquelette"
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PKC β pseudosubstrate acetate
<p>PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.</p>Degré de pureté :95.42%Couleur et forme :SoildBOS-172722
CAS :<p>BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).</p>Formule :C24H30N8ODegré de pureté :99.37%Couleur et forme :SolidMasse moléculaire :446.55Bosutinib
CAS :<p>Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.</p>Formule :C26H29Cl2N5O3Degré de pureté :98.98% - 99.9%Couleur et forme :Yellowish-Orange Or Pink To Brownish Solid Solid PowderMasse moléculaire :530.45Vedolizumab
CAS :<p>Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.</p>Degré de pureté :SDS-PAGE:98.4%;SEC-HPLC:99.1%Couleur et forme :LiquidMasse moléculaire :146.80 kDaIPI-493
CAS :<p>IPI-493 is a bioactive chemical.</p>Formule :C28H39N3O8Degré de pureté :>99.99%Couleur et forme :SolidMasse moléculaire :545.62Akt3 degrader 1
CAS :<p>Akt3 degrader 1 counters Osimertinib resistance in NSCLC, inhibits cell growth, and reduces mouse tumors.</p>Formule :C53H72N8O4Degré de pureté :98.12% - 99.02%Couleur et forme :SolidMasse moléculaire :885.19BNC105
CAS :<p>BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.</p>Formule :C20H20O7Degré de pureté :96.57%Couleur et forme :SolidMasse moléculaire :372.37N-Desmethyl imatinib
CAS :<p>N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.</p>Formule :C28H29N7ODegré de pureté :98.60%Couleur et forme :Off-White To Pale-Yellow SolidMasse moléculaire :479.582,3-Butanedione 2-Monoxime
CAS :<p>2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.</p>Formule :C4H7NO2Degré de pureté :98.62%Couleur et forme :Physical Description Cream-Colored Powder (Ntp 1992)Masse moléculaire :101.1Recilisib
CAS :<p>Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.</p>Formule :C16H13ClO4SDegré de pureté :98.85% - 98.96%Couleur et forme :SolidMasse moléculaire :336.79Abrilumab
CAS :<p>Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.</p>Degré de pureté :98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Couleur et forme :LiquidVerubulin hydrochloride
CAS :<p>Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic</p>Formule :C17H18ClN3ODegré de pureté :98.29% - 99.77%Couleur et forme :SolidMasse moléculaire :315.8RWJ 50271
CAS :<p>RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.</p>Formule :C18H17F3N4O2SDegré de pureté :99.09%Couleur et forme :SolidMasse moléculaire :410.41Danicamtiv
CAS :<p>Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.</p>Formule :C16H20F3N5O4SDegré de pureté :99.38%Couleur et forme :SolidMasse moléculaire :435.42Teplizumab
CAS :<p>Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.</p>Degré de pureté :SDS-PAGE:95.8%;SEC-HPLC:99.7%Couleur et forme :LiquidMasse moléculaire :145.79 kDaFluocinolone (Acetonide)
CAS :<p>Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.</p>Formule :C24H30F2O6Degré de pureté :99.29% - 99.82%Couleur et forme :Crystals From Acetone & Hexane SolidMasse moléculaire :452.49ADH-1 trifluoroacetate
CAS :<p>ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.</p>Formule :C24H35F3N8O8S2Degré de pureté :90.08% - 99.17%Couleur et forme :SolidMasse moléculaire :684.71Zagotenemab
CAS :<p>Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.</p>Degré de pureté :95% - > 95%Couleur et forme :LiquidMasse moléculaire :145.3 kDaAbciximab
CAS :<p>Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.</p>Degré de pureté :SDS-PAGE:95.2%;SEC-HPLC:95.9%Couleur et forme :LiquidMasse moléculaire :95.18 kDaImatinib Mesylate
CAS :<p>Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,</p>Formule :C29H31N7O·CH4SO3Degré de pureté :98% - >99.99%Couleur et forme :White Crystalline PowderMasse moléculaire :589.71Dasatinib
CAS :<p>Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.</p>Formule :C22H26ClN7O2SDegré de pureté :99.59% - 99.86%Couleur et forme :Pale-Yellow SolidMasse moléculaire :488.01Fluorofenidone
CAS :<p>Fluorofenidone (AKF-PD) slows kidney fibrosis by inhibiting NADPH oxidase/ECM via PI3K/Akt, akin to AMR69 but less toxic with a longer half-life.</p>Formule :C12H10FNODegré de pureté :99.85%Couleur et forme :SolidMasse moléculaire :203.21ATN-161 acetate
CAS :<p>ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.</p>Formule :C25H39N9O10SDegré de pureté :98.27%Couleur et forme :SoildMasse moléculaire :657.7CMPD101
CAS :<p>CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).</p>Formule :C24H21F3N6ODegré de pureté :99.01% - 99.04%Couleur et forme :SolidMasse moléculaire :466.46IMAB027
CAS :<p>Naratuximab (Anti-TSPAN26/CD37 Reference Antibody) is a humanized monoclonal antibody against CD37 that can be used to synthesize ADC compounds.</p>Degré de pureté :97.7% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.5% (SEC-HPLC)Couleur et forme :LiquidMosunetuzumab
CAS :<p>Mosunetuzumab (BCT-4465A) is an IgG1 antibody targeting CD20 & CD3, used for R/R B-NHL and refractory follicular lymphoma.</p>Degré de pureté :SDS-PAGE:94.4%;SEC-HPLC:96.1%Couleur et forme :LiquidMasse moléculaire :146.27 kDaAS1949490
CAS :<p>AS1949490, a selective SHIP-2 inhibitor with IC50 of 620 nM, boosts glucose metabolism by upregulating GLUT1 in L6 myotubes.</p>Formule :C20H18ClNO2SDegré de pureté :99.94%Couleur et forme :SolidMasse moléculaire :371.88Veltuzumab
CAS :<p>Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody that shows anti-proliferative, apoptotic and antibody-dependent cytotoxic effects in vitro.</p>Degré de pureté :97.7% (SDS-PAGE); 97.9% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.9% (SEC-HPLC)Couleur et forme :LiquidOtelixizumab
CAS :<p>Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.</p>Degré de pureté :>95%Couleur et forme :LiquidMeclofenamic acid sodium
CAS :<p>Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities.</p>Formule :C14H10Cl2NNaO2Degré de pureté :98% - 98.96%Couleur et forme :SolidMasse moléculaire :318.14Tubulin inhibitor 6
CAS :<p>Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.</p>Formule :C20H14ClNO2SDegré de pureté :99.05%Couleur et forme :SolidMasse moléculaire :367.85ALK inhibitor 2
CAS :<p>ALK inhibitor 2 is a new-type and selective inhibitor for the ALK kinase.</p>Formule :C23H28ClN7O3SDegré de pureté :99.77% - >99.99%Couleur et forme :SolidMasse moléculaire :518.03Vantictumab
CAS :<p>Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.</p>Degré de pureté :99% (SDS-PAGE); 97.7% (SEC-HPLC) - 99% (SDS-PAGE); 97.7% (SEC-HPLC)Couleur et forme :LiquidDonanemab
CAS :<p>Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.</p>Degré de pureté :95%Couleur et forme :LiquidPamidronate Disodium
CAS :<p>Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.</p>Formule :C3H9NNa2O7P2Degré de pureté :99.86% - 99.93%Couleur et forme :White CrystalsMasse moléculaire :279.03Gantofiban
CAS :<p>Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.</p>Formule :C21H29N5O6Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :447.48GRGDSP
CAS :<p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>Formule :C22H37N9O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :587.58Larazotide
CAS :<p>Larazotide: octapeptide from V. cholerae, treats Coeliac disease by inhibiting paracellular permeability.</p>Formule :C32H55N9O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :725.83DSPE-PEG2000-cRGD
<p>DSPE-PEG2000-cRGD is a PEG compound composed of DSPE and an αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to αvβ3 on the surface of various cancer cells and neovascular cells. This compound can be utilized for drug delivery.</p>Couleur et forme :Odour SolidPDS-0330
CAS :<p>PDS-0330, a claudin-1 inhibitor, hinders CRC growth and metastasis with micromolar affinity and promising pharmacokinetics.</p>Formule :C25H17N3O2SDegré de pureté :99.93%Couleur et forme :SoildMasse moléculaire :423.49hCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Couleur et forme :Odour SolidTubulin polymerization-IN-46
<p>Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breast</p>Formule :C22H25NO6Couleur et forme :SolidMasse moléculaire :399.44DSPE-PEG2000-iRGD
<p>DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.</p>Couleur et forme :Odour SolidSNIPER(ABL)-013
<p>SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of</p>Formule :C42H52F3N7O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :839.9Epothilone F
CAS :<p>Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.</p>Formule :C27H41NO7SCouleur et forme :SolidMasse moléculaire :523.68Zolbetuximab MMAE
<p>Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.</p>Degré de pureté :95% - 95%Couleur et forme :LiquidMasse moléculaire :150 kDahAChE-IN-1
<p>hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.</p>Formule :C22H24N4OCouleur et forme :SolidMasse moléculaire :360.45Foxy-5
CAS :<p>Foxy-5 is a wnt5a peptide mimetic</p>Formule :C26H42N6O12S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :694.776BrCaQ-C10-TPP
<p>6BrCaQ-C10-TPP inhibits TRAP1, halts cancer cell growth (IC50=0.008-0.30µM), disrupts mitochondrial membrane.</p>Formule :C45H47Br2N2O3PCouleur et forme :SolidMasse moléculaire :854.65trans-Dehydrocurvularin
CAS :<p>trans-Dehydrocurvularin is a useful organic compound for research related to life sciences. The catalog number is T125357 and the CAS number is 21178-57-4.</p>Formule :C16H18O5Couleur et forme :SolidMasse moléculaire :290.315
