Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1382 produits trouvés pour "Signalisation du cytosquelette"
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MC-Val-Cit-PAB-Ispinesib
CAS :<p>MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent Eg5 inhibitor and a click chemistry reagent [1].</p>Formule :C59H71ClN10O10Couleur et forme :SolidMasse moléculaire :1115.71β-Catenin modulator-2
CAS :<p>β-Catenin Modulator-2 (Compound IIa-130), which is an oxazole-thiazole derivative, serves as a potent and selective modulator of β-Catenin [1].</p>Formule :C20H18Cl2N2O3SCouleur et forme :SolidMasse moléculaire :437.34CNS-11
CAS :<p>CNS-11, a compound that disaggregates tau fibrils, is utilized in Alzheimer's disease (AD) research [1].</p>Formule :C25H21N3O2Couleur et forme :SolidMasse moléculaire :395.45PTK7/β-catenin-IN-1
CAS :<p>PTK7/β-catenin-IN-1 (compound 01065) is a potent inhibitor targeting PTK7/β-catenin and p53/MDM2, with IC50 values of 8.9 μM and 56.5 μM, respectively. This compound shows promise for cancer research applications [1].</p>Formule :C22H16N2O2Couleur et forme :SolidMasse moléculaire :340.382BI-1950
CAS :<p>BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.</p>Formule :C32H26Cl2FN7O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :646.5BX-2819
CAS :<p>BX-2819 is an Hsp90 inhibitor that exhibits potent antiproliferative activity with an IC50 of 41 nM .</p>Formule :C21H24N4O4SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :428.51UU-T01
CAS :<p>UU-T01 inhibits β-catenin/Tcf4 with Ki of 3.14 µM, binds β-catenin directly with KD of 0.531 µM.</p>Formule :C10H10N6OCouleur et forme :SolidMasse moléculaire :230.23Teclistamab
CAS :<p>Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.</p>Degré de pureté :95%Couleur et forme :Liquidβ-Catenin modulator-5
CAS :<p>β-Catenin Modulator-5 (Compound IIa-84), an oxazole and thiazole-based compound, serves as a potent and selective modulator of β-Catenin [1].</p>Formule :C21H22N2O2SCouleur et forme :SolidMasse moléculaire :366.48Flavokawain 1i
CAS :<p>Flavokawain 1i, a derivative of chalcones flavokawain A, flavokawain B, and flavokawain C, exhibits anticancer and antiviral properties.</p>Formule :C21H18O4Couleur et forme :SolidMasse moléculaire :334.37AKT-I-1
CAS :<p>AKT-I-1 is a selective and reversible inhibitor of Akt1.</p>Formule :C22H30N6Degré de pureté :99.89%Couleur et forme :SolidMasse moléculaire :378.51G-5555
CAS :<p>G-5555 is a potent inhibitor of p21-activated kinase 1 (PAK1) (Kis: 3.7 nM and 11 nM for PAK1 and PAK2, respectively).</p>Formule :C25H25ClN6O3Degré de pureté :99.76% - 99.84%Couleur et forme :SolidMasse moléculaire :492.96β-Catenin modulator-1
CAS :<p>β-Catenin modulator-1 (IIa-650) is a useful agent in cancer research for modulating β-Catenin [1].</p>Formule :C21H28N2O4SCouleur et forme :SolidMasse moléculaire :404.52JNJ-26076713
CAS :<p>JNJ-26076713, an oral alpha V integrin blocker, may treat macular edema, AMD, and diabetic retinopathy.</p>Formule :C29H38N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :490.64β-Catenin modulator-4
CAS :<p>β-Catenin modulator-4 (compound IIa-92), encompassing oxazole and thiazole moieties, acts as a potent and selective modulator of β-Catenin [1].</p>Formule :C21H21ClN2O2SCouleur et forme :SolidMasse moléculaire :400.92Luvixasertib hydrochloride
CAS :<p>CFI-402257 hydrochloride, a highly selective and orally bioavailable inhibitor targeting TTK/Mps1, demonstrates an in vitro IC50 value of 1.7 nM against TTK. This compound exhibits anti-cancer activity [1].</p>Formule :C28H31ClN6O3Couleur et forme :SolidMasse moléculaire :535.04TAS0612
CAS :<p>TAS0612, a novel oral inhibitor of RSK, AKT, and S6K, exhibits broad-spectrum antitumor activity by impeding cell growth [1].</p>Formule :C27H34F3N9O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :573.61PAK1-IN-1
CAS :<p>PAK1-IN-1: PAK1 inhibitor, IC50 9.8 nM, hinders tumor cell migration and invasion dose-dependently.</p>Formule :C26H20ClN5O2Couleur et forme :SolidMasse moléculaire :469.92Pivanex
CAS :<p>Pivanex, an oral HDAC inhibitor, targets metastasis, angiogenesis, reduces Bcr-Abl protein, and promotes apoptosis.</p>Formule :C10H18O4Degré de pureté :≥98%Couleur et forme :SolidMasse moléculaire :202.25ALM301
CAS :<p>ALM301: oral AKT inhibitor targeting AKT1, AKT2, AKT3; blocks AKT phosphorylation, curbs cancer cell growth.</p>Formule :C25H25N3O3Couleur et forme :SolidMasse moléculaire :415.48Dolastatinol
CAS :<p>Dolastatinol, a synthetic analog of Dolastatin 10, serves as a potent low-nanomolar inhibitor of tubulin polymerization.</p>Formule :C43H70N6O7SCouleur et forme :SolidMasse moléculaire :815.12αvβ1 integrin-IN-2
CAS :<p>αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.</p>Formule :C29H38N4O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :506.64SB-267268
CAS :<p>SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).</p>Formule :C22H24F3N3O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :451.44Valecobulin hydrochloride
CAS :<p>Valecobulin hydrochloride (CKD-516 hydrochloride) is the valine prodrug and vasoblocker of S516.Cost-effective and quality-assured.</p>Formule :C26H29ClN6O5SDegré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :573.06CCT-271850
CAS :<p>CCT-271850 is an inhibitor of the spindle checkpoint function of Monospindle 1.</p>Formule :C24H29N7ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :431.53Paluratide
CAS :<p>Paluratide (LUNA18) is a reversible KRAS inhibitor oral , which inhibits cancer cell proliferation by phosphorylating ERK and AKT, RAS with (GEFs).</p>Formule :C73H105F5N12O12Degré de pureté :98.70%Couleur et forme :SolidMasse moléculaire :1437.68Levocabastine
CAS :<p>Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.</p>Formule :C26H29FN2O2Couleur et forme :SolidMasse moléculaire :420.52ER degrader 7
CAS :<p>ER degrader 7 (Compound 35t) is a selective degrader of both ERα and ERβ, and possesses activity as a tubulin polymerization inhibitor.</p>Formule :C33H31F4N3O5SSeCouleur et forme :SolidMasse moléculaire :736.63Zaurategrast
CAS :<p>Zaurategrast is an effective and oral-effective inhibitor of the α4-integrin.</p>Formule :C26H25BrN4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :521.41Phenamacril
CAS :<p>Phenamacril (JS39919) is acyanoacrylate fungicide, has powerful inhibition against Fusarium species, especially to Fusarium graminearum.</p>Formule :C12H12N2O2Degré de pureté :99.52%Couleur et forme :SolidMasse moléculaire :216.24HSP90-IN-29
CAS :<p>HSP90-IN-29 (Compound 13), a benzoxazole derivative, serves as a potent and selective HSP-90 inhibitor, exhibiting a low IC50 value of 30 nM. This compound demonstrates significant antitumor activity [1].</p>Formule :C19H20ClN3O4Couleur et forme :SolidMasse moléculaire :389.83Akt-I-1,2
CAS :<p>Akt-I-1,2 is a selective inhibitor of Akt1 and Akt2.</p>Formule :C23H22ClN3Degré de pureté :99.95%Couleur et forme :SolidMasse moléculaire :375.893,4',5-Trismethoxybenzophenone
CAS :<p>3,4',5-Trismethoxybenzophenone (compound 16a) is an effective inhibitor of tubulin assembly, demonstrating a half-maximal inhibitory concentration (IC 50) of 2.6 µM [1].</p>Formule :C16H16O4Couleur et forme :SolidMasse moléculaire :272.3GRP78-IN-2
CAS :<p>GRP78-IN-2 inhibits surface GRP78, showing anti-angiogenic and anti-cancer properties, sparing normal cells.</p>Formule :C29H29NO6Couleur et forme :SolidMasse moléculaire :487.54Tirofiban HCl
CAS :<p>Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.</p>Formule :C22H37ClN2O5SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :477.06Iroxanadine sulfate
CAS :<p>Iroxanadine sulfate is a MAPK p38 inhibitor potentially for the treatment of atherosclerosis.</p>Formule :C14H22N4O5SCouleur et forme :SolidMasse moléculaire :358.41Integrin Antagonists 27
CAS :<p>Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.</p>Formule :C24H20N4O5Couleur et forme :SolidMasse moléculaire :444.44PAK4-IN-1
CAS :<p>PAK4-IN-1: selective, potent oral PAK4 inhibitor; stable in acid/neutral; shows strong anti-tumor in vivo.</p>Formule :C26H30ClN7O5Couleur et forme :SolidMasse moléculaire :556.01Porcn-IN-2
CAS :<p>Porcn-IN-2 (Example 107) is a potent Wnt pathway inhibitor, exhibiting an IC50 of 0.05 nM.</p>Formule :C24H17F3N6OCouleur et forme :SolidMasse moléculaire :462.43αvβ6 integrin inhibitor 2
CAS :<p>αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.</p>Formule :C21H30N4O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :386.49Risvodetinib
CAS :<p>Risvodetinib: potent inhibitor of protein tyrosine kinases c-Abl1, c-Abl2, and c-kit.</p>Formule :C33H34N8O2Couleur et forme :SolidMasse moléculaire :574.68Solitomab
CAS :<p>Solitomab (AMG 110) is a bispecific antibody targeting CD3 and EpCAM, used in uterine/ovarian carcinosarcoma research.</p>Couleur et forme :LiquidLitronesib
CAS :<p>Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.</p>Formule :C23H37N5O4S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :511.7Tubulin inhibitor 25
CAS :<p>Potent Tubulin inhibitor 25: IC50 0.98 μM, blocks HT29 cell growth, hinders cell migration & microtubule formation, anti-angiogenic.</p>Formule :C26H22O8Couleur et forme :SolidMasse moléculaire :462.45β-catenin-IN-6
CAS :<p>β-Catenin-IN-6 is an inhibitor of the canonical Wnt/β-catenin signaling pathway, effectively impeding the proliferation of human colorectal cancer cells and</p>Formule :C22H19ClN6OCouleur et forme :SolidMasse moléculaire :418.88KIF18A-IN-7
CAS :<p>KIF18A-IN-7 is an orally active inhibitor targeting KIF18A, demonstrating potent inhibition with an IC50 value of 9.4 nM against the microtubule-dependent</p>Formule :C27H35N3O5S2Couleur et forme :SoildMasse moléculaire :545.71MAO A/HSP90-IN-1
CAS :<p>MAO A/HSP90-IN-1 (4-b) is a dual inhibitor of MAO A and HSP90, exhibiting IC50 values of 1.77 μM in glioblastoma (GBM) GL26 cells and 0.019 μM against HSP90α.</p>Formule :C24H29ClN2O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :444.95LY2780301
CAS :<p>LY2780301, an oral Akt (protein kinase B) inhibitor, may hinder cancer cell growth and trigger apoptosis by blocking the PI3K/Akt pathway.</p>Formule :C25H27F4N7OCouleur et forme :SolidMasse moléculaire :517.52KSP-IA
CAS :<p>KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.</p>Formule :C21H22F2N2ODegré de pureté :98%Couleur et forme :SolidMasse moléculaire :356.41Lotrafiban hydrochloride
CAS :<p>Lotrafiban hydrochloride is an platelet glycoprotein IIb/IIIa blocker with oral activity.</p>Formule :C23H33ClN4O4Couleur et forme :SolidMasse moléculaire :464.99
