Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1382 produits trouvés pour "Signalisation du cytosquelette"
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Certepetide
CAS :<p>Certepetide, or iRGD, is a cyclic peptide that enhances tumor penetration and researches solid cancers.</p>Formule :C37H60N14O14S2Couleur et forme :SolidMasse moléculaire :989.09MS98
CAS :<p>MS98, a specific PROTAC AKT degrader, depletes T-AKT with DC50 of 78 nM; binds AKT1, AKT2, AKT3 with Kds of 4, 140, 8.1 nM.</p>Formule :C58H81ClN10O7SCouleur et forme :SolidMasse moléculaire :1097.86Gantofiban
CAS :<p>Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.</p>Formule :C21H29N5O6Degré de pureté :99.57%Couleur et forme :SolidMasse moléculaire :447.48BMP agonist 1
<p>BMP Agonist 1 (compound 2 b) is a small-molecule stimulator of bone morphogenic protein (BMP) signaling, crucial for the differentiation of C2C12 cells.</p>Formule :C21H16N2O6Couleur et forme :SolidMasse moléculaire :392.36SMS 121
CAS :<p>SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.</p>Formule :C20H21NO5Degré de pureté :98.29%Couleur et forme :SoildMasse moléculaire :355.38MAL3-101
CAS :<p>MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).</p>Formule :C54H66N4O10Couleur et forme :SolidMasse moléculaire :931.12Fuzapladib
CAS :<p>Fuzapladib (IS-741) is a PLA2 inhibitor that reduces Mac-1 expression to prevent inflammation and pancreatitis.</p>Formule :C15H20F3N3O3SDegré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :379.4Arimoclomol citrate
CAS :<p>Arimoclomol citrate boosts Hsp expression, aiding protein aggregation and neuron protection.</p>Formule :C20H28ClN3O10Couleur et forme :SolidMasse moléculaire :505.91SIAIS100
<p>SIAIS100, a potent BCR-ABL PROTAC degrader, demonstrates a DC50 value of 2.7 nM, highlighting its efficacy.</p>Formule :C44H50ClF2N9O5SCouleur et forme :SolidMasse moléculaire :890.44Peptide5
CAS :<p>Connexin43 peptide: lessens swelling, astrogliosis, inflammation, neuron death post-spinal injury; analgesic for neuropathic pain.</p>Formule :C60H98N16O20SCouleur et forme :SolidMasse moléculaire :1395.6K34c hydrochloride
CAS :<p>K34c hydrochloride is an alpha5β1 integrin antagonist for glioblastoma study.</p>Formule :C26H30ClN3O4Degré de pureté :99.76% - 99.89%Couleur et forme :SoildMasse moléculaire :483.99PM050489
CAS :<p>PM050489, a polyketone inhibitor from Lithoplocamia lithistoides, halts mitosis at 26.4 nM IC50 and aids cancer research.</p>Formule :C31H44ClN3O7Couleur et forme :SolidMasse moléculaire :606.15SRI 37892
CAS :<p>SRI 37892 is a Fzd7 inhibitor with potent activities against Wnt/β-catenin signaling and cancer cell viability.</p>Formule :C26H19N5O2SDegré de pureté :99.93%Couleur et forme :SolidMasse moléculaire :465.53Wortmannin-Rapamycin Conjugate
CAS :<p>Phosphoinositide 3-kinase (PI3K) and mammalian target of rapamycin (mTOR) act synergistically in promoting cancer.</p>Formule :C88H131N3O23Couleur et forme :SolidMasse moléculaire :1599.014c(phg-isoDGR-(NMe)k) TFA
<p>C(phg-isoDGR-(NMe)k) TFA is a selective and potent ligand for α5β1-integrin, exhibiting an IC50 of 2.9 nM [1].</p>Formule :C29H42F3N9O9Couleur et forme :SolidMasse moléculaire :717.69Solidagonic acid
CAS :<p>Solidagonic acid inhibits HSET, prevents fission yeast cell death, and hinders L. sativa and L. multiflorum seedling growth.</p>Formule :C22H34O4Couleur et forme :SolidMasse moléculaire :362.5YS-49 monohydrate
<p>YS-49, a PI3K/Akt activator, curbs RhoA/PTEN; inhibits VSMC growth by inducing HO-1; an isoquinoline alkaloid that stimulates cardiac β-adrenoceptors.</p>Formule :C20H22BrNO3Couleur et forme :SolidMasse moléculaire :404.3Akt/SKG Substrate Peptide
CAS :<p>substrate for Akt/PKB</p>Formule :C36H59N13O9Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :817.94MS170
CAS :<p>MS170, specific PROTAC AKT degrader, potent with DC 50 of 32 nM, binds AKT1/2/3 with Kd 1.3, 77, 6.5 nM respectively.</p>Formule :C45H56ClN9O7Couleur et forme :SolidMasse moléculaire :870.45Chaetominine
CAS :<p>Chaetominine is a type of cytotoxic alkaloid obtained from endophytic Chaetomium sp. IFB-E015.</p>Formule :C22H18N4O4Couleur et forme :SolidMasse moléculaire :402.40MS21
CAS :<p>MS21 is a unique AKT degrader that selectively hampers the proliferation of cancers with mutations in the PI3K/PTEN pathway, alongside wild-type KRAS and BRAF.</p>Formule :C58H79ClN12O6SCouleur et forme :SolidMasse moléculaire :1107.86Tubulin inhibitor 38
<p>Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cell</p>Formule :C17H13ClN6OSCouleur et forme :SolidMasse moléculaire :384.84Tubulin inhibitor 21
<p>Compound 6f, a chalcone-melatonin hybrid, is a potent tubulin inhibitor with IC50=0.26μM in SW480 cells, less toxic to non-cancer cells.</p>Formule :C28H25N3O4SCouleur et forme :SolidMasse moléculaire :499.58Orbofiban acetate
CAS :<p>Orbofiban Acetate is a compound that serves as an antagonist to the platelet GPIIb/IIIa receptor, effectively inhibiting platelet aggregation when administered</p>Formule :C19H27N5O6Couleur et forme :SolidMasse moléculaire :421.45Lys-Gln-Ala-Gly-Asp-Val
CAS :<p>KQAGDV is a fibrinogen γ-chain cell adhesion peptide, targeting α2bβ3 integrin, and binds SMCs.</p>Formule :C25H44N8O10Couleur et forme :SolidMasse moléculaire :616.66Vinzolidine
CAS :<p>Vinzolidine is a semi-synthetic vinca alkaloid. It exerts cytotoxic effects on tumor cells by inhibiting cell division through disruption of tubulin polymerization. Vinzolidine can be utilized in research to investigate synergy with other chemotherapy or biotherapy drugs, as well as cancer cell tolerance or resistance, and to explore strategies to overcome these challenges.</p>Formule :C48H58ClN5O9Couleur et forme :SolidMasse moléculaire :884.46Dihydrocephalomannine
CAS :<p>Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.</p>Formule :C45H55NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :833.928SQLE-IN-1
CAS :<p>SQLE-IN-1 is a SQLE inhibitor with antitumor activity that inhibits the proliferation of Huh7 and the protein expression of PI3K and AKT.</p>Formule :C24H21F2N5O2SDegré de pureté :99.89%Couleur et forme :SoildMasse moléculaire :481.52Fibronectin CS1 Peptide
CAS :<p>Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.</p>Formule :C38H64N8O15Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :872.96RA-PR058
<p>RA-PR058 is an orally active Ramalin derivative capable of penetrating the blood-brain barrier, with multi-target regulatory functions. By reducing BACE1 expression, decreasing excessive tau protein phosphorylation, and mitigating anxiety-like behaviors, along with displaying favorable pharmacokinetic properties, RA-PR058 shows promise as a multi-target modulator for Alzheimer's disease.</p>Formule :C11H15ClF3N3OCouleur et forme :SolidMasse moléculaire :297.7Alvespimycin TFA
<p>Alvespimycin (17-DMAG) TFA is a potent inhibitor of Hsp90, binding with an EC50 of 62 ± 29 nM.</p>Formule :C34H49F3N4O10Couleur et forme :SolidMasse moléculaire :730.34008Eudebeiolide B
CAS :<p>Eudebeiolide B, isolated from Salvia plebeia R.</p>Formule :C15H18O4Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :262.3DSPE-PEG1000-cRGD
<p>DSPE-PEG1000-cRGD is a PEG compound composed of DSPE and the αvβ3-targeting peptide (cRGD). The cRGD peptide specifically binds to the αvβ3 receptors present on the surfaces of various cancer cells and angiogenic vascular cells. DSPE-PEG1000-cRGD is applicable in drug delivery.</p>Couleur et forme :Odour SolidSNIPER(ABL)-047
<p>SNIPER(ABL)-047, a compound that links HG-7-85-01 (an ABL inhibitor) to MV-1 (an IAP ligand) via a linker, effectively decreases the BCR-ABL protein levels,</p>Formule :C67H82F3N11O9SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1274.5MPH-220
CAS :<p>MPH-220: Oral myosin-2 inhibitor, induces muscle relaxation, useful for spasticity research.</p>Formule :C20H21N3O3SCouleur et forme :SolidMasse moléculaire :383.46Anti-inflammatory agent 60
<p>Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, and reduces iNOS, phosphorylated p65, and β-catenin</p>Degré de pureté :98%Couleur et forme :Odour SolidTyrosine Kinase Inhibitor Library
<p>A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related</p>Couleur et forme :Odour SolidTubulin inhibitor 24
CAS :<p>Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.</p>Formule :C22H21N3O3Degré de pureté :99.99%Couleur et forme :SolidMasse moléculaire :375.42TNIK-IN-7
CAS :<p>TNIK-IN-7 is a Traf2 and Nck interacting kinase (TNIK) inhibitor with antitumor activity for the study of signaling and proliferation in colorectal cancer cells</p>Formule :C23H22N4O2Degré de pureté :99.87%Couleur et forme :SoildMasse moléculaire :386.45Jatrophone
CAS :<p>Jatrophone is a novel inhibitor of the macrocyclic diterpenoid tumor.</p>Formule :C20H24O3Couleur et forme :SolidMasse moléculaire :312.4Zolbetuximab
CAS :<p>Zolbetuximab (IMAB362) is a monoclonal antibody targeting Claudin-18.2 for certain gastrointestinal and pancreatic cancers.</p>Degré de pureté :95.3% (SDS-PAGE); 95.1% (SEC-HPLC) - 97%+Couleur et forme :LiquidMasse moléculaire :147.09 kDaMyelin Basic Protein
CAS :<p>Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system.</p>Formule :C60H103N21O17Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1390.59Bisindolylmaleimide III
CAS :<p>Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6</p>Formule :C23H20N4O2Degré de pureté :98.6%Couleur et forme :SolidMasse moléculaire :384.43β-catenin-IN-7
<p>β-Catenin-IN-7 (Compound 9) is an inhibitor of β-catenin that disrupts its interaction with Tcf-4, consequently impeding Wnt-dependent gene expression, and</p>Formule :C17H13BrN2O2SCouleur et forme :SolidMasse moléculaire :389.27Gamitrinib TPP hexafluorophosphate
CAS :<p>Gamitrinib TPP hexafluorophosphate is a mitochondrial-targeted HSP90 inhibitor with anticancer activity that can be used to study cancer and viral infection.</p>Formule :C52H65F6N3O8P2Degré de pureté :98.52% - 98.52%Couleur et forme :SolidMasse moléculaire :1036.03LXY3
CAS :<p>LXY3 (LXY2) is a VLA-3 blocking peptide that inhibits the interaction of neutrophil surface integrin α3β1 (VLA-3) with laminin in the basement membrane, thereby preventing neutrophil migration across the tumor vascular basement membrane barrier. LXY3 is employed to block the neutrophil-mediated release of nanoparticles from the perivascular pool into the tumor stroma and is frequently used for targeted imaging in breast cancer.</p>Formule :C32H43N11O15S2Couleur et forme :SolidMasse moléculaire :885.88SNIPER(ABL)-039
CAS :<p>SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of</p>Formule :C54H68ClN11O9S2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1114.77FAK-IN-7
CAS :<p>FAK-IN-7 has potential antiproliferative activity and is a FAK inhibitor.</p>Formule :C16H13N3OSDegré de pureté :98.18%Couleur et forme :SolidMasse moléculaire :295.36Pep2m, myristoylated
CAS :<p>Myristoylated pep2m peptide; inhibits GluA2-NSF interaction, reducing AMPA receptor function and surface expression.</p>Formule :C63H118N18O14SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :1383.8DynaMin inhibitory peptide, myristoylated
CAS :<p>Cell-permeable dynamin inhibitor; blocks its binding to amphiphysin, hindering endocytosis; curbs NMDA receptor internalization.</p>Formule :C61H107N19O14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1330.64
