Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1537 produits trouvés pour "Signalisation du cytosquelette".
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Gamitrinib TPP
CAS :Gamitrinib TPP targets mitochondrial HSP90, inhibiting cancer, and blocks mitochondrial matrix.Formule :C52H65N3O8PDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :891.078Tubulin inhibitor 38
Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cellFormule :C17H13ClN6OSCouleur et forme :SolidMasse moléculaire :384.84SNIPER(ABL)-013
SNIPER(ABL)-013, a compound that links GNF5 (ABL inhibitor) with Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 ofFormule :C42H52F3N7O8Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :839.9Combretastatin A-1 phosphate tetrasodium
CAS :OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.Formule :C18H18Na4O12P2Couleur et forme :SolidMasse moléculaire :580.2411H-Benzo[a]carbazole
CAS :11H-Benzo[a]carbazole is a kinesin-like protein KIF11 inhibitor that can inhibit the viability of HeLa cells.Formule :C16H11NDegré de pureté :99.14%Couleur et forme :SolidMasse moléculaire :217.27Tubulin polymerization-IN-50
Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cellFormule :C24H20FN3O3Couleur et forme :SolidMasse moléculaire :417.43hAChE-IN-1
hAChE-IN-1 (Compound 24) is a potent inhibitor of human acetylcholinesterase (hAChE), exhibiting an inhibition concentration half-maximum (IC50) of 1.09 μM.Formule :C22H24N4OCouleur et forme :SolidMasse moléculaire :360.45Tubulin inhibitor 45
Tubulin inhibitor 45 (compound 5) functions as an inhibitor of the active site of tubulin. It exhibits IC50 values of 11 μM for MCF7 cancer cells and 13 μM for HePG2 cancer cells.Formule :C19H18N2O2SCouleur et forme :SolidMasse moléculaire :338.1089MAL3-101
CAS :MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).Formule :C54H66N4O10Couleur et forme :SolidMasse moléculaire :931.12MS170
CAS :MS170, specific PROTAC AKT degrader, potent with DC 50 of 32 nM, binds AKT1/2/3 with Kd 1.3, 77, 6.5 nM respectively.Formule :C45H56ClN9O7Couleur et forme :SolidMasse moléculaire :870.45CCT 031374 hydrobromide
CAS :CCT 031374 hydrobromide is a TCF/β-catenin inhibitor with antitumor activities.Formule :C23H20BrN3ODegré de pureté :99.50%Couleur et forme :Yellow SolidMasse moléculaire :434.33Ref: TM-T21685
1mg35,00€5mg67,00€1mL*10mM (DMSO)82,00€10mg100,00€25mg197,00€50mg313,00€100mg447,00€200mg587,00€Tabituximab barzuxetan
CAS :Tabituximab barzuxetan: Humanized antibody FZD-10-targeted, Yttrium-90 labeled, for synovial sarcoma research.Couleur et forme :SolidG-5555 hydrochloride (1648863-90-4 free base)
G-5555 hydrochloride is a potent and selective p21-activated kinase 1 (PAK1) inhibitor with a Ki of 3.7 nM.Formule :C25H26Cl2N6O3Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :529.42Arimoclomol citrate
CAS :Arimoclomol citrate boosts Hsp expression, aiding protein aggregation and neuron protection.Formule :C20H28ClN3O10Couleur et forme :SolidMasse moléculaire :505.91Tubulin polymerization-IN-62
Tubulin polymerization-IN-62 (Compound 14b) is a microtubule polymerization inhibitor (IC50 of 7.5 μM) that also functions as a degradation agent for α-/β-tubulin. This compound suppresses the proliferation of cancer cells MCF-7, A549, and HCT-116 with IC50 values of 32, 60, and 29 nM, respectively. It induces G2/M phase cell cycle arrest and inhibits the migration of MCF-7 cells. In a 4T1 syngeneic mouse model, Tubulin polymerization-IN-62 demonstrates antitumor efficacy with a tumor growth inhibition rate (TGI) of 74.27%.Formule :C37H44N4O4Couleur et forme :SolidMasse moléculaire :608.33626Neuropeptide DF2
CAS :Neuropeptide DF2 is an FMRFamide-related neuropeptide from crayfish.Formule :C44H67N15O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :966.1SPA107
CAS :SPA107 (Hemiasterlin methyl ester) is an analogue of Hemiasterlin. It inhibits tubulin polymerization, exhibiting antimitotic activity with an IC50 of 0.5 nM. SPA107 also shows cytotoxicity against p53 mutated MCF-7 cells, with an IC50 of 0.5 nM.Formule :C31H48N4O4Couleur et forme :SolidMasse moléculaire :540.74Odulimomab
CAS :Odulimomab: anti-LFA-1 antibody, inhibits T cell growth, protects against ischemic injury, used in transplant rejection research.Couleur et forme :LiquidMicrotubule-associated protein tau (26-44)
Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.Formule :C83H127N25O34SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :2051.11Aberrant tau degrader 2
CAS :Aberrant tau degrader 2 (Compound 4-12) acts as a degrader of tau protein and serves as a target protein ligand for the synthesis of PROTAC degrader C004019.Formule :C19H27N7O3SCouleur et forme :SolidMasse moléculaire :433.528
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