Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1585 produits trouvés pour "Signalisation du cytosquelette"
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MPC-0767
CAS :MPC-0767, a potent, selective, and orally active hsp90 inhibitor, is the L-alanine ester prodrug of MPC-3100, exhibiting enhanced chemical stability.
Formule :C26H36BrN7O9S2Couleur et forme :SolidMasse moléculaire :734.64KIF2C-IN-1
KIF2C-IN-1 (Compound 7S9) is a selective and potent small molecule inhibitor of KIF2C. It stabilizes the interaction between KIF2C and microtubule proteins, preventing the depolymerization of polyglutamylated microtubules. KIF2C-IN-1 enhances the cytotoxicity of Paclitaxel in Paclitaxel-resistant triple-negative breast cancer (TNBC) cells and, when combined with Paclitaxel, significantly reduces tumor growth in mouse models.Formule :C36H39ClN4O9SCouleur et forme :SolidMasse moléculaire :738.212637-Epi-10-oxo-docetaxel
CAS :7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.Formule :C43H51NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :805.86trans-Dehydrocurvularin
CAS :trans-Dehydrocurvularin is a useful organic compound for research related to life sciences. The catalog number is T125357 and the CAS number is 21178-57-4.Formule :C16H18O5Couleur et forme :SolidMasse moléculaire :290.315Zolbetuximab
CAS :Zolbetuximab (IMAB362) is a monoclonal antibody targeting Claudin-18.2 for certain gastrointestinal and pancreatic cancers.
Degré de pureté :95.3% (SDS-PAGE); 95.1% (SEC-HPLC) - 97%+Couleur et forme :LiquidMasse moléculaire :147.09 kDaLDV
CAS :α4β1 integrin (VLA-4) ligand (Kd ~ 12 nM). Non-fluorescent derivative of LDV FITC.Formule :C48H70N10O12Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :979.13Ceratamine A
CAS :Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.
Formule :C17H16Br2N4O2Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :468.14TAT-P110
CAS :TAT-P110 is a peptide inhibitor that disrupts the interaction between Drp1 and Fis1, effectively reducing pathological changes in various models of neurodegenerative diseases, ischemia, and sepsis without impairing the physiological function of Drp1.Formule :C100H178N44O26Masse moléculaire :2412.76LDV-FITC TFA
LDV-FITC TFA is a fluorescent peptide, specifically an FITC-conjugated LDV peptide. This compound binds to the α4β1 integrin with high affinity, displaying a Kd of 0.3 nM in the presence of Mn2+ and 12 nM in its absence, when binding to U937 cells. LDV-FITC TFA is useful for assessing α4β1 integrin affinity.Formule :C69H81N11O17S·xC2HF3O2KSP ligand 1
CAS :KSP ligand 1 is a protein ligand that targets KSP (Kinesin) and can be used in the synthesis of PROTAC KSP-IN-1 for cancer research.Formule :C25H23NO3SCouleur et forme :SolidMasse moléculaire :417.52Bisindolylmaleimide III
CAS :Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC).Bisindolylmaleimide III selectively interacts with PKCα or ribosomal S6Formule :C23H20N4O2Degré de pureté :97.2%Couleur et forme :SolidMasse moléculaire :384.43ARM165
ARM165 is a heterobifunctional molecule that degrades the protein PIK3CG and inhibits the PI3Kγ-Akt signaling pathway, thereby exerting anti-leukemic effects. It is capable of suppressing the proliferation of AML cells, with an IC50 of less than 1 μM.Formule :C44H51N7O8SMasse moléculaire :837.35198Anti-inflammatory agent 60
Anti-inflammatory agent 60 (compound 21) inhibits nitric oxide production, presenting an IC50 of 12.95 μM, and reduces iNOS, phosphorylated p65, and β-cateninDegré de pureté :98%Couleur et forme :Odour SolidDihydrocephalomannine
CAS :Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.Formule :C45H55NO14Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :833.928DSPE-PEG3000-iRGD
DSPE-PEG3000-iRGD is a PEG compound comprising DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrin and undergoes proteolytic cleavage within tumors to produce CRGDK/R, interacting with neuropilin-1. This results in tumor targeting and penetration capabilities. DSPE-PEG3000-iRGD is applicable in drug delivery.Couleur et forme :Odour Solid[Ala107]MBP(104-118)
CAS :Synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 46 - 145 mM).Formule :C67H104N20O19Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :1493.68Risuteganib
CAS :Risuteganib is a synthetic RGD (arginyl-glycyl-aspartic acid)-class peptide that regulates the functions of multiple integrin isoforms.
Formule :C22H39N9O11SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :637.66β-catenin-IN-7
β-Catenin-IN-7 (Compound 9) is an inhibitor of β-catenin that disrupts its interaction with Tcf-4, consequently impeding Wnt-dependent gene expression, andFormule :C17H13BrN2O2SCouleur et forme :SolidMasse moléculaire :389.27Variabilin
CAS :Variabilin is a natural product that can be used as a reference standard. The CAS number of Variabilin is 3187-52-8.Formule :C17H16O5Couleur et forme :SolidMasse moléculaire :300.31Neuropeptide DF2
CAS :Neuropeptide DF2 is an FMRFamide-related neuropeptide from crayfish.Formule :C44H67N15O10Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :966.1
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