Signalisation du cytosquelette
Les inhibiteurs de la signalisation du cytosquelette sont des composés qui perturbent les voies de signalisation régulant le cytosquelette, essentiel pour la forme, la motilité, la division des cellules et le transport intracellulaire. Ces inhibiteurs sont utilisés pour étudier la dynamique des protéines du cytosquelette, telles que l'actine et la tubuline, et leur rôle dans des processus comme la migration cellulaire, l'adhésion et la métastase du cancer. Les inhibiteurs de la signalisation du cytosquelette sont précieux dans la recherche en biologie cellulaire, en cancérologie et en neurobiologie. Chez CymitQuimica, nous offrons une gamme complète d'inhibiteurs de la signalisation du cytosquelette de haute qualité pour soutenir vos recherches dans ces domaines.
1577 produits trouvés pour "Signalisation du cytosquelette"
Trier par
Degré de pureté (%)
0
100
|
0
|
50
|
90
|
95
|
100
Gaspantatug
CAS :Gaspantatug is a humanized IgG1κ antibody that targets CLDN18.2, with the corresponding isotype control being HumanIgG1kappa [Isotype Control].Couleur et forme :LiquidPDK-IN-1
CAS :PDK-IN-1, a PDK inhibitor, IC50: 0.03μM (PDK1), 0.1μM (HSP90), reduces tumor mass.Formule :C20H16BrN7OCouleur et forme :SolidMasse moléculaire :450.29TAT-Gap19
CAS :Cx43 blocker, IC50 ~7μM; doesn't affect gap junctions/Panx1. TAT motif enhances effect; works in vivo, brain-penetrant.Formule :C119H212N46O26Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :2703.28PKCδ Peptide Substrate
CAS :PKCδ Peptide Substrate is a highly specific substrate for the δ-type of Protein kinase C, composed of a sequence that mirrors murine eEF-1α (422-443) andFormule :C109H191N35O29SCouleur et forme :SolidMasse moléculaire :2487.97SMS 121
CAS :SMS 121 is a novel CD36 inhibitor that impairs fatty acid uptake and cell viability in acute myeloid leukaemia (AML) cells.Formule :C20H21NO5Degré de pureté :98.29%Couleur et forme :SoildMasse moléculaire :355.38MS133
MS133 is a human bispecific antibody targeting CD133/PROM1 and CD3E. It is used in the study of colon cancer.Couleur et forme :Odour LiquidINY-03-041 trihydrochloride
INY-03-041 trihydrochloride: potent, selective PROTAC AKT degrader; combines Ipatasertib and Lenalidomide; IC50s: AKT1 (2.0 nM), AKT2 (6.8 nM), AKT3 (3.5 nM).Formule :C44H59Cl4N7O5Couleur et forme :SolidMasse moléculaire :907.8AT-1002
CAS :AT-1002 is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide.Formule :C32H53N9O7SDegré de pureté :98%Couleur et forme :SolidMasse moléculaire :707.88AS-605240 potassium
AS-605240 (potassium) is an orally active PI3Kγ inhibitor with an IC50 of 8 nM and a Ki of 7.8 nM. It inhibits MCP-1 and CSF1-induced PKB phosphorylation with IC50 values of 0.181 µM and 0.550 µM, respectively. In mouse models of peritonitis induced by RANTES (CCL5) and thioglycolate, AS-605240 (potassium) reduces neutrophil recruitment, showing EC50 values of 9.1 mg/kg and 10 mg/kg. Additionally, AS-605240 (potassium) ameliorates arthritis induced by αCII-IA in mice.Formule :C12H6KN3O2SCouleur et forme :SolidMasse moléculaire :294.98178Etrolizumab
CAS :MEDI-578 is a CHO-expressed humanized monoclonal antibody targeting NGF/bNGF for the study of neurological and immune system disorders.Degré de pureté :98.9% (SDS-PAGE); 96.6% (SEC-HPLC) - 98.9% (SDS-PAGE); 96.6% (SEC-HPLC)Couleur et forme :LiquidMasse moléculaire :144.1 kDaPhallacidin
CAS :Phallacidin, a phallotoxin family member, targets and binds to F-actin in mushroom toxins.Formule :C37H50N8O13SCouleur et forme :SolidMasse moléculaire :846.91STX-100
PY314 is a CHO-expressed humanized monoclonal antibody targeting TREM2 with antitumor activity for the study of metastatic renal cell carcinoma.Degré de pureté :97.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.3% (SDS-PAGE); 97.5% (SEC-HPLC)Couleur et forme :Odour LiquidMasse moléculaire :145.12 kDaCyclo(RGDfC) TFA
Zelminemab (AMG-301) is a humanized monoclonal antibody targeting ADCYAP1R1 for use in neurological disorders.Formule :C26H35F3N8O9SDegré de pureté :98.59%Couleur et forme :SolidMasse moléculaire :692.67Protein kinase C α peptide TFA
CAS :Protein Kinase C (alpha) Peptide (TFA) is a PKC-α-associated peptide functioning as a lipid-dependent serine/threonine protein kinase.Formule :C68H115F3N24O26SCouleur et forme :SolidMasse moléculaire :1773.85Chromeceptin
CAS :Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway.Formule :C19H16F3N3ODegré de pureté :99.85%Couleur et forme :SoildMasse moléculaire :359.35NLS-StAx-h
Wnt inhibitor; halts cancer cell growth & spread by blocking β-catenin, IC50=1.4μM, cell-permeable.Formule :C161H275N55O29Degré de pureté :98%Couleur et forme :SolidMasse moléculaire :3445.26Phomopsinamine
CAS :Phomopsinamine, a phomopsin A derivative, hampers microtubule assembly in sheep brain tubulin (IC50: 0.53-0.59 μM).Formule :C32H43ClN6O8Couleur et forme :SolidMasse moléculaire :675.17A20FMDV2
CAS :A20FMDV2 is a highly selective αvβ6 integrin inhibitor with an IC 50 of 3 nM, demonstrating 1,000-fold greater selectivity for αvβ6 compared to other RGD-directed integrins like αvβ3, αvβ5, and α5β1. This compound can be derived from the foot-and-mouth disease virus and is suitable for radiolabeling, enabling PET imaging of αvβ6 integrin-positive tumors.Formule :C93H163N31O28Couleur et forme :SolidMasse moléculaire :2163.48Microtubule destabilizing agent-1
CAS :Compound 12b is a hydroxamic acid-based MDA with stable metabolism, high bioavailability, and strong antitumor properties.Formule :C22H26N4O4Couleur et forme :SolidMasse moléculaire :410.47GSK 3008348 hydrochloride
CAS :GSK 3008348 hydrochloride is an αvβ6 integrin inhibitor used to confirm idiopathic pulmonary fibrosis.Formule :C29H37N5O2xHClDegré de pureté :99.54%Couleur et forme :SolidMasse moléculaire :0
