
Composés deutérés
4238 produits trouvés pour "Composés deutérés"
Decanoic Acid-1,2-13C2
CAS :Produit contrôléApplications Labelled Decanoic Acid (D212525). Decanoic acid is used in manufacturing of esters for artificial fruit flavors and perfumes.
References Oro, L., et al.: Acta Pharmacol. Toxicol., 18, 141 (1961),Formule :C813C2H20O2Couleur et forme :NeatMasse moléculaire :174.25Dichloroacetic Acid-d1
CAS :Produit contrôléApplications The microwace spectra of Dichloroacetic Acid-d1 consists of many weak absorption lines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Van Zoeren, E., et al.: J. Mol. Struct., 97, 315-322 (1983);Formule :C2DHCl2O2Couleur et forme :NeatMasse moléculaire :129.948Ethyl-d5 Paraben
CAS :Produit contrôléApplications Labelled Ethylparaben. An antimicrobial agent used in cosmetic products.
References Gilliland, D., et al.: J. Appl. Bacteriol., 72, 258 (1992), Routledge, E., et al.: Toxicol. Appl. Pharmacol., 153, 12 (1998), Miller, C., et al.: J. Biol. Chem., 272, 32824 (1997), Nakagawa, Y., et al.: Biochem. Pharmacol., 55, 1907 (1998),Formule :C9H5D5O3Couleur et forme :NeatMasse moléculaire :171.22-Hydroxy Fluorene-d9
CAS :Produit contrôléApplications A labelled metabolite of polycyclic aromatic hydrocarbons in humans.
References Jacob, J., et al.: Xenobiotica, 12, 45 (1982), Becher, G., et al.: Cancer Lett., 17, 301 (1983), Hoffmann, D., et al.: Cancer Treat. Res., 72, 1 (1995), Einolf, H., et al.: Chem. Res. Toxicol., 10, 609 (1997),Formule :C13HD9OCouleur et forme :White To Off-WhiteMasse moléculaire :191.27Maleic Hydrazide-d2
CAS :Produit contrôléApplications Labelled abalogue of Maleic Hydrazide, a compound used in plant growth regulator formulations.
References Calliera, M. et al.: Pest Manag. Sci., 62, 1168 (2006); Berrada, H., et al.: Food Control. 21, 36 (2010); Nougadere, A. et al.: Food Chem. Toxicol., 49, 1484 (2011);Formule :C4H2D2N2O2Couleur et forme :NeatMasse moléculaire :114.12-Isopropyl-d7 Thioxanthone
CAS :Produit contrôléApplications A labelled thioxanthone derivative useful as photoinitiators.
References le Fur, Y., et al.: J. Agric. Food Chem., 47, 2860 (1999), Sanz, M., et al.: Food Chem., 84, 133 (2004), Herent, M., et al.: J. Pharm. Biomed. Anal., 43, 886 (2007),Formule :C16H7D7OSCouleur et forme :Light YellowMasse moléculaire :261.39Dibromomethane-d2
CAS :Produit contrôléApplications Dibromomethane-d2 is the labelled analogue of Dibromomethane (D425645), a compound used as a solvent, gauge fluid, and in organic synthesis. It is a convenient agent for converting catechols to their methylenedioxy- derivatives.
References Podsiadlo M., et al.: Acta Cryst., B62, 1090 (2006);Formule :CD2Br2Couleur et forme :NeatMasse moléculaire :175.852,4-Dihydroxybenzophenone-d5
CAS :Produit contrôléApplications 2,4-Dihydroxybenzophenone-d5 is deuterium labelled of 2,4-Dihydroxybenzophenone (D451780), which is a metabolite of Benzophenone (B204980). Benzophenone can be used to synthesize antihistamines, hypnotics and insecticides.
References Li, M.H., et al.: Toxicol. Environ. Chem., 94, 566 (2012); Leon, Z.. et al.: Anal. Bioanal. Chem., 398, 831 (2010); Bechard, K., et al.: Aquat. Toxicol., 90, 310 (2008)Formule :C13D5H5O3Couleur et forme :Off-White To Light YellowMasse moléculaire :219.251-Adamantan-d15-amine
CAS :Produit contrôléApplications 1-Adamantan-d15-amine is a labeled NMDA-receptor antagonist. Antiviral; antiparkinsonian.
References Vernier, V.G., et al; Toxicol. Appl. Pharmacol., 15, 642 (1969); Kirschbaum, J., et al.: Anal. Profiles Drug Subs., 12, 1 (1983)Formule :C102H15H2NCouleur et forme :White To BeigeMasse moléculaire :166.34O,O-Diethyl Dithiophosphate-13C4 Ammonium Salt
CAS :Produit contrôléApplications Labelled O,O-Diethyl Dithiophosphate (D444265). Used in the synthesis of novel phosphorothioates and phosphorodithioates as cholinesterase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Millard, C., et al.: J. Neurochem., 64, 1909 (1995), Nicolet, Y., et al.: J. Biol. Chem., 278, 41141 (2003), Casida, J., et al.: Chem. Res. Toxicol., 17, 983 (2004),Formule :C4H14NO2PS2Couleur et forme :NeatMasse moléculaire :207.23Ethylamine Hydrochloride-d3
CAS :Produit contrôléStability Hygroscopic
Applications Ethylamine Hydrochloride-d3 is the isotope labelled analog of Ethylamine Hydrochloride (E898290); a chemical used in various chemical organic syntheses and biological studies.
References Miller, M.M. et al.: Bioorg. Med. Chem. Lett., 22, 6503 (2012); Yasui, K. et al.: Prot. Sci., 19, 486 (2010)Formule :C2D3H4N·ClHCouleur et forme :White To Off-WhiteMasse moléculaire :84.56Benzyl-d7 Alcohol
CAS :Produit contrôléStability Hygroscopic
Applications Benzyl Alcohol (D7, 98%) (cas# 71258-23-6) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageFormule :C7D7HOCouleur et forme :NeatMasse moléculaire :115.18Trimethyl-d9-sulfonium Iodide
CAS :Produit contrôléApplications Trimethyl-d9-sulfonium Iodide (CAS# 106776-17-4) is a useful isotopically labeled research compound.
Formule :C3D9S·ICouleur et forme :White To Off-WhiteMasse moléculaire :213.1285Regorafenib-d3
CAS :Produit contrôléApplications Regorafenib-d3 is the isotope labelled analog of Regorafenib (R143000); a compound that inhibits PDGFR tyrosine kinase with IC50=83nM and is useful for the treatment of inflammation. Also an anti-proliferative agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)Formule :C21H12D3ClF4N4O3Couleur et forme :NeatMasse moléculaire :485.83Triethylenephosphoramide-d12
CAS :Produit contrôléApplications Labelled TEPA (T776600). Used as insect chemosterilant; in dyeing. Antineoplastic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gaines, et al.: Toxicol. Appl. Pharmacol., 14, 515 (1969), Huitema, A., et al.: Br. J. Clin. Pharmacol., 51, 61 (2001), Jinno, H., et al.: Drug Metab. Dispos., 31, 398 (2003),Formule :C6D12N3OPCouleur et forme :NeatMasse moléculaire :185.23Myristic Acid-d27
CAS :Produit contrôléApplications Myristic Acid (D27, 98%) (cas# 60658-41-5) is a useful research chemical.
Formule :C14D27HO2Degré de pureté :98%Couleur et forme :Off-WhiteMasse moléculaire :255.54Potassium Thiocyanate-13C,15N
CAS :Produit contrôléStability Moisture Sensitive
Applications Isotope labelled Potassium Thiocyanate has been used as a catalyst in a one-pot reaction of dialkyl acetylenedicarboxylates with indane-1,3-dione. Potassium Thiocyanate has been used as a selective bacterial inhibitor to create ESS-3 broth to allow co-enrichment of the target pathogens and suppress growth of some non-target pathogens
References Hassanabadi, A., Zhiani, R., et. al.: J. Chem. Res., 37, 458 (2013); Zhang, Q., et. al.: Plant. Biotech., 29, 103 (2012)Formule :C15NS·KCouleur et forme :NeatMasse moléculaire :99.17N-Methyl-N-nitroso Urea-d5 (Wetted with water >20%)
CAS :Produit contrôléApplications N-Methyl-N-nitroso Urea-d6 is the labelled form of N-Methyl-N-nitroso Urea (M325815), which is a precursor of Diazomethane. It has a cytotoxicity effect.
References Huggins, C., et al.: J. Exp. Med., 131, 321 (1970); Gullino, P.M., et al.: J. Natl. Cancer Inst., 54, 401 (1975)Formule :C2D5N3O2Couleur et forme :NeatMasse moléculaire :108.11n-Dipropylamine-d4 Hydrochloride
CAS :Produit contrôléApplications n-Dipropylamine-d4 Hydrochloride (cas# 1329834-71-0) is a compound useful in organic synthesis.
Formule :C6H12D4ClNCouleur et forme :NeatMasse moléculaire :141.68Thiourea-13C
CAS :Produit contrôléApplications Thiourea-13C is an isotope labelled version of Thiourea (T375450). Hyperpolarized Thiourea-13C is used as an analyte in the real-time in vivo detection of hydrogen peroxide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wibowo, Arif, et al.: ACS Chem. Bio., 12(7), 1737-1742 (2017)Formule :CH4N2SCouleur et forme :NeatMasse moléculaire :77.11Ethyl-D5-Amine Hydrochloride
CAS :Produit contrôléStability Hygroscopic
Applications The labelled version of Ethylamine Hydrochloride, a chemical used in various chemical organic syntheses and biological studies.
References Miller, M.M. et al.: Bioorg. Med. Chem. Lett., 22, 6503 (2012); Yasui, K. et al.: Prot. Sci., 19, 486 (2010);Formule :C2D5H2N·ClHCouleur et forme :NeatMasse moléculaire :86.58n-Decyl-d21-trimethylammonium Bromide
CAS :Produit contrôléApplications n-Decyl-d21-trimethylammonium Bromide (CAS# 1515861-67-2) is a useful isotopically labeled research compound.
Formule :C13H9D21BrNCouleur et forme :White To Off-WhiteMasse moléculaire :301.425-Chloro-2-pyridinamine-3,4,6-d3
CAS :Produit contrôléApplications 5-Chloro-2-pyridinamine-3,4,6-d3 is labelled 5-Chloro-2-pyridinamine which is an intermediate used to synthesize zopiclone (Z700500), a cyclopyrrolone member of a family of non-benzodiazepine GABAA receptor agonists.
References Noble, S., et al.: Drugs, 55, 277 (1998), Musch, B., et al.: Int. J. Clin. Psychopharmacol., 5, 147 (1990)Formule :C5D3H2ClN2Couleur et forme :NeatMasse moléculaire :131.58Azoxystrobin-d4
CAS :Produit contrôléApplications Strobilurin fungicide; inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1. Agricultural fungicide. Used in Pesticide detection.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Smalling, K., et al.: Environ. Toxicol. Chem., 29, 2593 (2010), Lu, X., et al.: Phytopathol., 100, 1162 (2010), Schafer, R., et al.: Environ. Sci. Technol., 45, 1665 (2011),Formule :C222H4H13N3O5Couleur et forme :NeatMasse moléculaire :407.41Advantame-D3
CAS :Produit contrôléApplications Advantame-D3 is a labelled analogue of Advantame (A307000(M)), which is a combination of Aspartame (A790015) and Vanillin (V097500). Advantame was developed as a high-intensity, low calorie sweetener that is 20,000 times sweeter than sucrose.
References Bloomgarden, Z.: Diabetes Care, 34, e46 (2011); Otabe, A., et al.: Food Chem. Toxicol., 49, S49 (2011); Renwick, A.: Food Chem. Toxicol., 49, S1 (2011)Formule :C24D3H27N2O7Couleur et forme :NeatMasse moléculaire :461.523Bezafibrate-d4
CAS :Produit contrôléApplications Bezafibrate-d4 (cas# 1189452-53-6) is a compound useful in organic synthesis.
Formule :C19H16D4ClNO4Couleur et forme :Off-WhiteMasse moléculaire :365.841,3-Dichloro-2-propanol-d5
CAS :Produit contrôléApplications A labelled chloropropanol which shows toxic effects.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Andersen, H., et al.: Toxicology, 136, 67 (1999), Fry, J., et al.: Food Chem. Toxicol., 37, 351 (1999), Garle, M., et al.: Xenobiotica, 29, 533 (1999),Formule :C3D5HCl2OCouleur et forme :ColourlessMasse moléculaire :134.02D-Tyrosine-d2
CAS :Produit contrôléApplications D-Tyrosine-d2 is deuterium labelled D-Tyrosine (T899970). D-Tyrosine, the stereoisomer to L-Tyrosine (T899975), is an amino acid used in various organic syntheses for antibiotics. It is used in the synthesis of (-)-anisomycin, as well as BATSI (boronic acid transition state inhibitors) which act on β-lactamases. It has also been studied as an inhibitor of microbial growth on surfaces, reducing microbial attachment to hydrophillic glass and hydrophobic polypropylene surfaces.
References Li, Ji. et al.: Chin. Chem. Lett., 23, 647 (2012); Xu, H. et al.: Water Res., 45, 5796 (2011); Ke, W. et al.: Antimicrob. Agents Chemother., 55, 174 (2011)Formule :C9D2H9NO3Couleur et forme :NeatMasse moléculaire :183.2Sulfamonomethoxine-d4
CAS :Produit contrôléApplications Labelled Sulfamonomethoxine. Protein binding. Inhibitor of enzyme. Sulfamonomethoxine and Trimethoprim are used for treating porcine unknown hyperpyrexia.
References Bridges, et al.: Biochem. J., et al.: 96, 829 (1965), Hong, Y.-L., et al.: Antimicrob. Agents Chemother., 39, 1756 (1995)Formule :C11H8D4N4O3SCouleur et forme :NeatMasse moléculaire :284.335,5-(Diphenyl-d10) Hydantoin
CAS :Produit contrôléApplications 5,5-(Diphenyl-d10) Hydantoin is deuterium labelled Diphenylhydantoin (D491650), which is an anticonvulsant agent that suppresses abnormal brain activity associated with seizure. Diphenylhydantoin is used to treat ulcers, epidermolysis bullosa, chorea, Parkinson’s syndrome, trigeminal neuralgia, acute alcoholism, and inflammatory conditions (1,2).
References (1) Kim, S. H., et al.: Birth Defects Res B Dev Reprod Toxicol. 95, 337 (2012)(2) Younes, N., et al.: Dermatol Online J. 12, 5 (2006)Formule :C152H10H2N2O2Couleur et forme :White To Off-WhiteMasse moléculaire :262.33Folpet-d4
CAS :Produit contrôléApplications Labelled Folpet (F402000). Agricultural fungicide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cohen, S., et al.: Crit. Rev. Toxicol., 40, 531 (2010), Wong, J., et al.: J. Agric. Food Chem., 58, 5884 (2010),Formule :C92H4Cl3NO2SCouleur et forme :Off-WhiteMasse moléculaire :300.58Anthracene-d10
CAS :Produit contrôléApplications Anthracene-d10 is an isotope labelled analogue of Anthracene (A678400), an polycyclic aromatic hydrocarbon found readily as an component in coal tar. Anthracene is also used in the preparation of various dyes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the packageFormule :C142H10Couleur et forme :White To Light YellowMasse moléculaire :188.29Phthalic Acid Anhydride-d4
CAS :Produit contrôléApplications Labelled analogue of Phthalic Acid Anhydride, an organic reagent used to synthesize phthalates.
Formule :C8D4O3Couleur et forme :Off White SolidMasse moléculaire :152.143,4-Diaminopyridine-d3
CAS :Produit contrôléApplications 3,4-Diaminopyridine-d3 is the deuterium labelled analog of the drug 3,4-Diaminopyridine (D415950), which is used as a reagent in the preparation of 9-deazaxanthine derivatives which has activity as dual A2A antagonists/MAO-B inhibitors with potential as anti-Parkinson's agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rivara, S., et al.: J. Med. Chem., 56, 1247 (2013)Formule :C5H4D3N3Couleur et forme :NeatMasse moléculaire :112.151,3,5-Tribromobenzene-d3
CAS :Produit contrôléApplications 1,3,5-Tribromobenzene-d3 (CAS# 52921-77-4) is a useful isotopically labeled research compound.
Formule :C6D3Br3Couleur et forme :NeatMasse moléculaire :317.82Disulfiram-d20
CAS :Produit contrôléApplications Labelled Disulfiram. It is used as rubber accelerator; vulcanizer; seed disinfectant; fungicide; alcohol deterrent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Child, C., et al.: Acta Pharmacol. Toxicol., 8, 305 (1952), Nash, N.G., et al.: Anal. Profiles Drug Subs., 4, 168 (1975),Formule :C102H20N2S4Couleur et forme :NeatMasse moléculaire :316.66rac 3-Hydroxybutyric Acid-d4 Sodium Salt
CAS :Produit contrôléStability Hygroscopic
Applications Labelled rac 3-Hydroxybutyric Acid (H833020). Optically active 3-hydroxybutyric acids are key intermediates of the biosynthesis and metabolism of fatty acids and exist widely in biological systems.
References Freeman, J., et al.: Pediatrics, 102, 1358 (1998), Thio, L., et al.: Neurology, 54, 325 (2000), Rho, J., et al.: Epilepsia, 43, 358 (2002),Formule :C42H4H3O3·NaCouleur et forme :White To Off-WhiteMasse moléculaire :130.11N-(4-Amino-3-pyridinyl)-acetamide-d3 Hydrochloride
CAS :Produit contrôléFormule :C7H6D3N3O•HClCouleur et forme :NeatMasse moléculaire :190.64Indole-4,5,6,7-d4
CAS :Produit contrôléApplications Indole-4,5,6,7-d4 is a labelled analogue of Indole (I577320), which can be used in perfumes and in the synthesis of tryptophan. It is also an intermediate in synthesizing Indoleacetic Acid-13C6 (I577343), which has the potential to be used in anti-cancer therapy in conjunction with horseradish peroxidase (HRP).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kawano, T. et al.: Gen. Hypo. 60, 664 (2003);Formule :C8H3D4NCouleur et forme :NeatMasse moléculaire :121.17n-Dotriacontane-d66
CAS :Produit contrôléApplications n-Dotriacontane-d66 (CAS# 62369-68-0) is a useful isotopically labelled research compound. It has been studied as a potential generator to supply charged particles to plastic nuclear track detectors for high-energy neutrons.
References Oda, K., et al.: Radiation Measurements, 36, 119 (2003)Formule :C32D66Couleur et forme :Off-WhiteMasse moléculaire :517.27Sodium Beta-Hydroxyethoxyacetate-d4
CAS :Produit contrôléApplications Isotope labelled Sodium β-Hydroxyethoxyacetate is used in the synthesis of polymer microspheres that are magnetized and are used for enzyme catalysis or bioaffinity separations.
References Horak, D. et al.: Macromol. Biosci., 12, 647 (2012); Pestov, A. et al.: Russ. J. Coord. Chem., 38, 738 (2012);Formule :C4H3D4NaO4Couleur et forme :NeatMasse moléculaire :146.11Acrylamide-13C3
CAS :Applications Acrylamide-13C3 is carbon-13 labeled Acrylamide (A191300). Acrylamide is a chemical intermediate in production of polyacrylamides that are use in protein electrophoresis (PAGE), synthesis of dyes and copolymers for contact lenses. It is reasonably anticipated to be a human carcinogen (1,2).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References (1) Mottram, D.S., et al.: Nature, 419, 448 (2002)(2) Tareke, E., et al.: J. Agric. Food Chem., 50, 4998 (2002)Formule :C3H5NOCouleur et forme :NeatMasse moléculaire :74.062-Aminobiphenyl-2',3',4',5',6'-d5
CAS :Produit contrôléApplications Has a mutagenic potency
References Cash, G., et al.: Mutat. Res., 491, 31 (2001), Cash, G., et al.: Environ. Toxicol. Chem., 21, 2095 (2002), Glende, C., et al.: Mutat. Res., 515, 15 (2002),Formule :C12H6D5NCouleur et forme :NeatMasse moléculaire :174.25Methyl Diethyldithiocarbamate-d3
CAS :Produit contrôléApplications A labelled metabolite of a mixed disulfide S-(N,N-diethyldithiocarbamoyl)-N-acetyl-L-cysteine (AC-DDTC), an antimutagenic mixed disulfide from disulfiram.
References Madan, A., et al.: Drug Metab. Dispos., 23, 1153 (1995), Lambert, D., et al.: J. Med. Chem., 48, 5059 (2005), Tsuboi, K., et al.: J. Biol. Chem., 280, 11082 (2005),Formule :C6H10D3NS2Couleur et forme :NeatMasse moléculaire :166.322-(Chloromethyl)-8-(1,1-dimethylethyl)-1,4-dioxaspiro[4.5]decane-d4
CAS :Produit contrôléApplications 2-(Chloromethyl)-8-(1,1-dimethylethyl)-1,4-dioxaspiro[4.5]decane-d4 is an intermediate used in the synthesis of Spiroxamine-d4 (S683502), which is the labeled analogue of Spiroxamine (S683500), which is a spiroketalamine fungicide for use on cereal crops. Spiroxamine inhibits ergosterol synthesis. Spiroxamine is used as agricultural fungicide.
References Wang, J., et al.: J. Agric. Food Chem., 53, 1857 (2005), Abrahim, A., et al.: J. Pharm. Biomed. Anal., 51, 131 (2010), Wang, J., et al.: Anal. Bioanal. Chem., 396, 1513 (2010),Formule :C13D4H19ClO2Couleur et forme :ColourlessMasse moléculaire :250.798Propylparaben-d4
CAS :Produit contrôléApplications Propylparaben-d4 is the labelled analogue of propyl 4-hydroxybenzoate (P838285), which is an antimicrobial agent used in cosmetic products.
References Gilliland, D., et al.: J. Appl. Bacteriol., 72, 258 (1992), Routledge, E., et al.: Toxicol. Appl. Pharmacol., 153, 12 (1998), Miller, C., et al.: J. Biol. Chem., 272, 32824 (1997), Nakagawa, Y., et al.: Biochem. Pharmacol., 55, 1907 (1998),Formule :C10H12O3Couleur et forme :White To Off-WhiteMasse moléculaire :184.2251Hexanoic-5,5-d2 Acid
CAS :Produit contrôléApplications Hexanoic-5,5-d2 Acid (CAS# 55320-68-8) is a useful isotopically labeled research compound.
Formule :C6H10D2O2Couleur et forme :ColourlessMasse moléculaire :118.171,4-Dinitrosopiperazine-d8
CAS :Produit contrôléStability Hygroscopic
Applications Labelled 1,4-Dinitrosopiperazine. N,N'-Dinitrosopiperazine (DNP) induces nasopharyngeal carcinoma (NPC) and shows organ specificity to the nasopharyneal epithelium.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lanier, A., et al.: Cancer, 46, 2100 (1980), Waalkes, M., et al.: Carcinogenesis, 25, 133 (2004), Toth, E., et al.: Int. J. Cancer, 121, 1744 (2007),Formule :C4D8N4O2Couleur et forme :Off-White To Light YellowMasse moléculaire :152.181DL-Serine-2,3,3-d3
CAS :Produit contrôléApplications Labelled DL-Serine is used in the synthesis of novel tryptoline derivatives as IDO (indoleamine 2,3-Deoxygenase) inhibitors, for potential use in Alzheimer’s treatment.
References Tanaka, M. et al.: Bioorg. Med. Chem., 21, 1159 (2013);Formule :C32H3H4NO3Couleur et forme :NeatMasse moléculaire :108.111-Nitrosopyrrolidine-d4
CAS :Produit contrôléApplications Isotope Labelled 1-Nitrosopyrrolidine (N545950), which is one of the N-nitroso compounds (NOCs) implicated in human colon carcinogenesis, but the toxicological mechanisms involved have not been elucidated. Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
References 1. Singer, S. et al.: J. Med. Chem. 1985 Aug;28(8):1088-93.2. Tomatis, L. et al.: Carcinogenesis. 1997 Jan;18(1):97-105.3. Helguera, A. et al.: Toxicol Appl Pharmacol. 2007 Jun 1;221(2):189-202.Formule :C42H4H4N2OCouleur et forme :YellowMasse moléculaire :104.14S-Phenyl-d5-mercapturic Acid
CAS :Produit contrôléApplications An important isooptically labelled metabolite of benzene.
References Muller, G., et al. : Anal. Hazard. Sust. Biol. Mater., 5, 143 (1997)Formule :C112H5H8NO3SCouleur et forme :Off-White To BrownMasse moléculaire :244.32N-Acetyl-S-(3-hydroxypropyl-1,1,2,2,3,3-D6)cysteine, Dicyclohexylammonium Salt
CAS :Produit contrôléApplications N-Acetyl-S-(3-hydroxypropyl-1,1,2,2,3,3-D6)cysteine Dicyclohexylammonium Salt is labelled N-Acetyl-S-(3-hydroxypropyl)cysteine Dicyclohexylammonium Salt (A179075), which is a metabolite of halopropanes.
References Barnsley, E.A.: Biochem. J., 100, 362 (1966)Formule :C12H23N·C8D6H9NO4SCouleur et forme :Off-WhiteMasse moléculaire :408.6287Flavanone-d5
CAS :Produit contrôléApplications Labelled Propafenone (P757500) impurity.
References Kitagawa, S., et al.: Biol. Pharm. Bull., 29, 1 (2006), Boccard, J., et al.: Eur. J. Pharm. Sci., 36, 254 (2009)Formule :C15H7D5O2Couleur et forme :NeatMasse moléculaire :229.294,5-Dimethyl-3-hydroxy-2(5H)-furanone-13C2
CAS :Applications 4,5-Dimethyl-3-hydroxy-2(5H)-furanone-13C2 is a labelled analogue of 4,5-Dimethyl-3-hydroxy-2(5H)-furanone (D473600). 4,5-Dimethyl-3-hydroxy-2(5H)-furanone is a fragrant compound that is a key indicator of maple syrup urine disease, a disorder affecting newborn children that is the result of its inability to properly metabolize Valine (V094205), Leucine (L330110) and Isoleucine (I820175). 4,5-Dimethyl-3-hydroxy-2(5H)-furanone is naturally found in fenugreek seeds, and is an odourant present in sherry wines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Blank, I., et al.: Prog. Flav. Prec. Stud., No vol. given, 103 (1993); Guerra, P. & Yaylayan, V.: J. Agr. Food Chem., 59, 4699 (2011); Mackenzie, D. & Woolf, L.: Brit. Med. J., 1, 90 (1959); Podebrad, F., et al.: J. Inh. Metab. Dis., 22, 107 (1999)Formule :C2C4H8O3Couleur et forme :Light YellowMasse moléculaire :130.11n-Undecyl-1,1,2,2-d4 Alcohol
CAS :Produit contrôléApplications n-Undecyl-1,1,2,2-d4 Alcohol (CAS# 1219803-47-0) is a useful isotopically labeled research compound.
Formule :C11D4H20OCouleur et forme :NeatMasse moléculaire :176.34Thiamine hydrochloride phosphate-d3
CAS :Produit contrôléApplications Thiamine hydrochloride phosphate-d3 was used as a reagent in the redn. of cytochrome c in its reaction with thiamine and its structural analogs.
References Vovk, A. I, et al.: Russian J. of Gen. Chem. 72(11), 1808-1812. (2002)Formule :C12D3H15N4O4PS·Cl·HClCouleur et forme :NeatMasse moléculaire :420.272,3,5,6-Tetrabromo-p-xylene-d6
CAS :Produit contrôléFormule :C8D6Br4Couleur et forme :White To Off-WhiteMasse moléculaire :427.79o-Anisidine-d7
CAS :Produit contrôléApplications o-Anisidine is a highly toxic environmental pollutant and digestive system carcinogen. It is also a toxin that has been identified to be present in cigarettes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Coggins, C.R.E. et al.: Inhal. Toxicol., 23, 41 (2011); Dracinska, H. et al.: Neuroendorinol. Lett., 27, 9 (2006); Naiman, K. et al.: Neuroendocrinol. Lett., 31, 36 (2010);Formule :C72H7H2NOCouleur et forme :Orange To Dark BrownMasse moléculaire :130.25-Bromopentanoic-3,3,4,4-d4 Acid
CAS :Produit contrôléApplications Isotope labelled 5-Bromopentanoic Acid used in the synthesis of inhibitors for aminoglycoside resistant bacteria. Also used in the preparation of sequence specific base pair mimics as topoisomerase IB inhibitors.
References Vong, K. et al.: ACS Chem. Biol., 7, 470 (2012); Vekhoff, P. et al.: Biochem., 52, 43 (2012);Formule :C5D4H5BrO2Couleur et forme :NeatMasse moléculaire :185.05N,N-Dimethylformamide-d7
CAS :Produit contrôléApplications N,N-Dimethylformamide-d7 is the isotope labelled analog of N,N-Dimethylformamide. N,N-Dimethylformamide-d7 is used as a cofactor for enzymic oxidation of brassinin, which allows the transformation of dithiocarbamate group into an aldehyde equivalent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Pedras, M., et al.: Bioorg. Med. Chem., 19, 1390 (2011);Formule :C32H7NOCouleur et forme :ColourlessMasse moléculaire :80.14Tris(2-butyloxyethyl)phosphate-d27
CAS :Produit contrôléApplications Tris(2-butyloxyethyl)phosphate-d27 is the isotope analog of Tris(2-butyloxyethyl)phosphate. Tris(2-butyloxyethyl)phosphate,is an organophosphate, that can be used in the preparation of flame retardant, such as viscose fiber.
References Wang, Y., et al.: Fangzhi Xuebao, 33, 16 (2012); Xiaoshan, L. et al.: Aquatic Toxicology, 114, 173 (2012);Formule :C18H12D27O7PCouleur et forme :ColourlessMasse moléculaire :425.64Furfural-3,4,5-d3
CAS :Produit contrôléApplications Furfural-3,4,5-d3 (CAS# 53599-40-9) is a useful isotopically labeled research compound.
Formule :C5D3HO2Couleur et forme :YellowMasse moléculaire :99.10255,6-Dihydro Thymine-d6
CAS :Produit contrôléApplications Isotope labelled 5,6-Dihydrothymine is a derivative of Thymine, a nucleobase in the nucleic acid of DNA. 5,6-Dihydrothymine is a radiolysis product of DNA.
References Hubbard, K. et al.: Biochemistry, 28, 4382 (1989); Cadet, J. et al.: Int. J. Rad. Biol. Rel. Stud. Phys. Chem. Med., 39, 119 (1981);Formule :C52H6H2N2O2Couleur et forme :NeatMasse moléculaire :134.172,4-Xylidine-d6
CAS :Produit contrôléStability Air Sensitive
Applications 2,4-Xylidine-d6 is labelled 2,4-Xylidine (X749690) which is an aniline derived chemical reagent used in the synthesis of antiarrhythmic compounds. It is also used as a reactant in the synthesis of anticonvulsants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kalinin, D. et al.: Eur. J. Med. Chem., 63, 144 (2013); Ragavendran, J. et al.: Eur. J. Med. Chem., 42, 146 (2007);Formule :C82H6H5NCouleur et forme :NeatMasse moléculaire :127.22n-Pentacosane-d52
CAS :Produit contrôléApplications n-Pentacosane-d52 (CAS# 121578-13-0) is a useful isotopically labeled research compound.
Formule :C25D52Couleur et forme :White To Off-WhiteMasse moléculaire :405.011-[(4-Chlorophenyl)phenylmethyl]piperazine-d8
CAS :Produit contrôléApplications A labelled analog of a metabolite of Cetirizine and Hydroxyzine.
Formule :C172H8H11ClN2Couleur et forme :Colourless To YellowMasse moléculaire :294.85Cyromazine-d4
CAS :Produit contrôléStability Hygroscopic
Applications Labelled Cyromazine (C989300). Insect growth regulator. Insecticide.
References Hall, R.D., et al.: J. Econ. Entomol., 73, 564 (1980), Hart, R.J., et al.: Aust. Vet. J., 59, 104 (1982),Formule :C62H4H6N6Couleur et forme :White To Light YellowMasse moléculaire :170.21Hexamethylbenzene-d18
CAS :Produit contrôléApplications Hexamethylbenzene-d18 (cas# 4342-40-9) is a useful research chemical.
Formule :C12D18Couleur et forme :White To Off-WhiteMasse moléculaire :180.382Diphenyl Phthalate-3,4,5,6-d4
CAS :Produit contrôléApplications Diphenyl Phthalate-3,4,5,6-d4 (CAS# 1398065-61-6) is a useful isotopically labeled research compound.
Formule :C202H4H10O4Couleur et forme :NeatMasse moléculaire :322.35Benzhydrol-d5
CAS :Produit contrôléApplications Intermediate in the preparation of labelled Modafinil (M482500).
References Kumar, C., et al.: Eur. J. Med. Chem., 44, 1223 (2009),Formule :C13D5H7OCouleur et forme :NeatMasse moléculaire :189.262-Furoic Acid-d3
CAS :Produit contrôléApplications 2-Furoic Acid-d3 is the labeled analogue of 2-Furoic Acid (F863775), a heterocyclic carboxylic acid that is widely used in food products as a preservative and flavouring agent.
References Hall, I.H., et al.: Arch, Pharm., 326, 15 (1993)Formule :C5D3HO3Couleur et forme :NeatMasse moléculaire :115.12-Chloronaphthalene-d7
CAS :Produit contrôléApplications 2-Chloronaphthalene-d7 (CAS# 93951-84-9) is a useful isotopically labeled research compound.
Formule :C102H7ClCouleur et forme :NeatMasse moléculaire :169.661-Hexanol-d11
CAS :Produit contrôléApplications 1-Hexanol-d11 is the labelled analogue of 1-Hexanol (H281220), a perturbing agent on actomyosin ATPase and and was found to modulate the function of actomyosin motor via intermediate-specific structural perturbation.
References Komatsu, H., et al.: J. Muscle. Res. Cell. Motil., 25, 77 (2004); Hua, J.F., et al.: J. Insect. Physiol., 59, 690 (2013);Formule :C6D11H3OCouleur et forme :NeatMasse moléculaire :113.243iso-Butyl 4-Hydroxybenzoate-2,3,5,6-d4
CAS :Produit contrôléApplications iso-Butyl 4-Hydroxybenzoate-2,3,5,6-d4 (CAS# 1219805-33-0) is a useful isotopically labeled research compound.
Formule :C112H4H10O3Couleur et forme :NeatMasse moléculaire :198.252,5-Furandicarboxylic Acid-13C6
CAS :Produit contrôléApplications 2,5-Furandicarboxylic Acid-13C6 is isotopically labelled analogue of 2,5-Furandicarboxylic Acid (F863750), which is Furan (F863650) derivative that can be produced from biomass derived sugars using catalytic processes.
References Tong, X., et al.: Appl. Catal., A, 385, 1 (2010);Formule :C6H4O5Couleur et forme :NeatMasse moléculaire :162.05Chlorpyriphos-methyl-d6
CAS :Produit contrôléFormule :C72H6HCl3NO3PSCouleur et forme :NeatMasse moléculaire :328.57Fipronil Detrifluoromethylsulfinyl-13C2 15N2
CAS :Applications Fipronil-detrifluoromethylsulfinyl-3C2 15N2, is the unlabeled analogue of Fipronil-detrifluoromethylsulfinyl, that can be used in the synthesis of Fipronil (F342200), which is a GABA receptor antagonists and insecticides.
References Ling, S., et al.: App. Entomol. Zool., 44, 543 (2009), Li, X., et al.: Environ. Toxicol. Chem., 29, 127 (2010), Savant, R., et al.: J. Agric. Food Chem., 58, 1447 (2010),Formule :C913C2H5Cl2F3N215N2Couleur et forme :NeatMasse moléculaire :325.06rac-Propranolol-d7
CAS :Produit contrôléStability Hygroscopic
Applications rac-Propranolol-d7, is the labeled analogue of Propranolol (P831800), a β−Adrenergic blocker. Antihypertensive; antianginal; antiarrhythmic (class II).
References Bond, et al.: Nature, 213, 721 (1967), Hansteen, V., et al.: Br. Med. J., 284, 155 (1982), Diamond, S., et al.: J. Clin. Pharmacol., 28, 193 (1988),Formule :C162H7H14NO2Couleur et forme :NeatMasse moléculaire :266.39Monopentyl Phthalate-d4
CAS :Produit contrôléApplications A labelled metabolite of Di-n-pentyl phthalate (DPP), used mainly as a plasticizer in nitrocellulose.
References Schmid, P., et al.: Xenobiotica, 1985, 15, 251 (1985), Nativelle, C., et al.: Food Chem. Toxicol., 37, 905 (1999), Howdeshell, K., et al.: Toxicol. Sci., 105, 153 (2008),Formule :C13D4H12O4Couleur et forme :White To Off-WhiteMasse moléculaire :240.12997Molinate-d5
CAS :Produit contrôléApplications Isotope labelled Molinate (M486477), which is a herbicide that is used to control broad-leaved and grassy plants in rice and other crops (1,2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Nacher-Mestre, J. et al.: J. Agri. Food. Chem. 2014 Mar 12;62(10):2165-742. Sugrue, E. et al.: Appl. Environ. Microbiol. 2015 Apr;81(7):2612-24.Formule :C9H12D5NOSCouleur et forme :Light Yellow To YellowMasse moléculaire :192.33Sodium DL-Lactate-d3 (60% w/w in H2O)
CAS :Produit contrôléApplications Labelled Sodium DL Lactate used as coatings in the food industry, providing antimicrobial resistance
References Zhang, H. et al.: J. Food Sci., 74, M418 (2009); Jiang, Z. et al.: J. Food Sci., 76, M22 (2011);Formule :C32H3H2O3·NaCouleur et forme :Single SolutionMasse moléculaire :115.081-Butanol-d10 (n-Butyl Alcohol-d10)
CAS :Produit contrôléApplications Isotope labelled 1-Butanol (n-Butyl Alcohol), a common chemical reagent used in biodiesel production. Also it has been used in the study the polarization of vapor-deposited 1-butanol films (1) as well as in the preparation of bioavailable CB1 antagonists (2) . Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
Formule :C42H10OCouleur et forme :NeatMasse moléculaire :84.184-Dimethylaminosulfotoluidide-d7
CAS :Produit contrôléApplications 4-Dimethylaminosulfotoluidide-d7 is an isotope labelled intermediate in the synthesis of Tolylfluanide (T536730), a polyvalent sulfamide fungicide that is closely related to dichlofluanide.
References Wainwright, A. et al.: Bright. Crop Prot. Conf. Pests Dis., 1, 275 (1996)Formule :C9H7D7N2O2SCouleur et forme :NeatMasse moléculaire :221.33Drometrizole-d3
CAS :Produit contrôléStability Hygroscopic
Applications Isotope labelled Drometrizole is an intermediate reactant in the synthesis of UV light absorbers for polyester fibers.Formule :C13H8D3N3OCouleur et forme :Off-WhiteMasse moléculaire :228.26Nor Harmane-d7
CAS :Produit contrôléApplications The compund has cytotoxic effects. Labelled Norharmane.
References Elfarra, A., et al.: Drug Metab. Dispos., 26, 779 (1998), Da Costa, A., et al.: Biocell, 23, 65 (1999), Janetzky, B., et al.: Drug Dev. Res., 46, 51 (1999), Kutty, R., et al.: Toxicol. Appl. Pharmacol., 107, 377 (1991), Riederer, F., et al.: J. Neurochem., 81, 814 (2002), Schott, Y., et al.: Bioorg. Med. Chem. Lett., 16, 5840 (2006),Formule :C11HD7N2Couleur et forme :NeatMasse moléculaire :175.24Glutaric-d4 Acid
CAS :Produit contrôléApplications Glutaric Acid (2,2,4,4-D4, 98%) (cas# 19136-99-3) is a useful research chemical.
Formule :C5D4H4O4Couleur et forme :NeatMasse moléculaire :136.14Cinnamic Acid-13C3
CAS :Applications Cinnamic Acid-13C3 is the labelled analogue of Cinnamic Acid which is rac-form of trans-Cinnamic Acid (P336185) that is used in the synthesis of amides and esters through coupling reactions involving carboxylic acids and amines and N-methylation of amides and O-methylation of carboxylic acids.
References Kunishima, M. et al.: Tetrahedron, 55, 13159 (1999); Xia, Q. et al.: Org. Lett., 15, 3326 (2013);Formule :C613C3H8O2Couleur et forme :White To Off-WhiteMasse moléculaire :151.14Thiodiglycolic Acid-d4
CAS :Produit contrôléApplications Thiodiglycolic Acid-d4 acts as a reagent for the synthesis of metabolites of S-carboxymethyl-L-cysteine and S-methyl-L-Cysteine and of some isotoically labelled (2H, 13C) analogs.
References Meese, C. O., et al.: Archiv der Pharmazie, 323, 957 (1990)Formule :C4D4H2O4SCouleur et forme :NeatMasse moléculaire :154.171,4-Butane-2,2,3,3-d4-diamine 2HCl
CAS :Produit contrôléApplications 1,4-Butane-2,2,3,3-d4-diamine 2HCl (CAS# 88972-24-1) is a useful isotopically labeled research compound.
Formule :C4H10D4Cl2N2Couleur et forme :White To Off-WhiteMasse moléculaire :165.098cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester-d5
CAS :Produit contrôléApplications cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester-d5 is an isotopic analog of cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester. cis-7,10,13,16-Docosatetraenoic Acid Ethyl Ester is an ethyl analog of cis-7,10,13,16-Docosatetraenoic Acid (D494510). cis-7,10,13,16-Docosatetraenoic Acid has been identified as a protein kinase inhibitor, affecting serotonin levels in studies.
References Mirnikjoo, B. et al.: J. Biol. Chem., 276, 10888 (2001);Formule :C24D5H35O2Couleur et forme :NeatMasse moléculaire :365.604Homarine-d3
CAS :Produit contrôléStability Hygroscopic
Applications Labelled Homarine (H458500). Quaternary ammonium base occurring in tissues of marine animals.
References Stein, W., et al.: J. Biol. Chem., 211, 915 (1954), Bystedt, J., et al.: J. Sci. Food Agric., 10, 301 (1959),Formule :C7H4D3NO2Couleur et forme :NeatMasse moléculaire :140.152-(2-Aminoethyl)-3-(4-chlorophenyl)-3-hydroxyphthalimidine-d4 Hydrochloride (Mazindol Metabolite)
CAS :Produit contrôléApplications A labelled metabolite of Mazindol. An imidazolinylphenyl ketone derivatives as antidepressants and diuretics.
References Guengerich, F., et al.: Chem. Res. Toxicol., 14, 611 (2001), Murray, S., et al.: Xenobiotica, 31, 135 (2001), Lewis, D., et al.: Drug Metab. Rev., 34, 55 (2002), de Graaf, C., et al.: J. Med. Chem., 48, 2725 (2005),Formule :C16H12D4Cl2N2O2Couleur et forme :NeatMasse moléculaire :343.24Acetoin-13C4
CAS :Applications Acetoin-13C4 is the labeled analogue of the unlabeled (A163775), which is used in food flavoring and fragrances and is also found in some fruits and vegetables.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Dutta, S.M. et al.: Ind. J. Dairy Sci., 24, 107 (1971);Formule :C4H8O2Couleur et forme :NeatMasse moléculaire :92.081,2-Propanediol-d6
CAS :Produit contrôléApplications 1,2-Propanediol-d6 is the d6 labelled analogue of 1,2-Propanediol (P760310) which is used in the preparation of polymers, existing as a linker unit. Also used in the preparation of colchine derivatives as anticancer agents.
References Wayakron Phetphaisit, C. et al.: Int. J. Ad. Adhesion. 41, 127 (2013); Shen, L. et al.: Asian J. Chem., 25, 3294 (2013);Formule :C3D6H2O2Couleur et forme :NeatMasse moléculaire :82.13141-Naphthoic Acid-d7
CAS :Produit contrôléApplications 1-Naphthoic Acid-d7 (cas# 634179-80-9) is a compound useful in organic synthesis.
Formule :C112H7HO2Couleur et forme :NeatMasse moléculaire :179.225-Hydroxy Propafenone Hydrochloride-d5
CAS :Produit contrôléApplications 5-Hydroxy Propafenone Hydrochloride-d5 is a labeled analogue of 5-Hydroxy Propafenone Hydrochloride (H952450), a metabolite of Propafenone (P757500), a sodium channel blocker. Antiarrhythmic (class IC).
References Hege, H.G., et al.: Eur. J. Drug Metab. Pharmacokinet., 9, 41 (1984); Hollmann, M., et al.: Arzneim.-Forsch., 33, 763 (1983); Bryson, H. M., et al.:Drugs, 45, 85 (1993); Rae, A. P., et al.: Am. J. Cardiol., 82, 59N (1998)Formule :C21H23D5ClNO4Couleur et forme :NeatMasse moléculaire :398.94N-Desethyl Amodiaquine-d5
CAS :Produit contrôléApplications A labelled metabolite of Amodiaquine (A634200), an antimalarial.
References Bayliss, M., et al.: Xenobiotica, 29, 253 (1999), Projean, D., et al.: Drug Metab. Dispos., 31, 748 (2003), Bray, P., et al.: Mol. Microbiol., 56, 323 (2005), Xiang, H., et al.: J. Pharm. Sci., 95, 2657 (2006),Formule :C18H13D5ClN3OCouleur et forme :Light Yellow To BrownMasse moléculaire :332.84Di-n-decyl Phthalate-3,4,5,6-d4
CAS :Produit contrôléApplications Di-n-decyl Phthalate-3,4,5,6-d4 (CAS# 1276197-18-2) is a useful isotopically labeled research compound.
Formule :C282H4H42O4Couleur et forme :Light YellowMasse moléculaire :450.6871Gallic Acid-d2
CAS :Produit contrôléApplications Gallic Acid-d2 is the labelled analogue of Gallic acid (G188978) which is a phenolic acid with antioxidant activity. Gallic acid was found to protect human cells against oxidative damage and showed cytotoxicity against cancer cells. Gallic Acid and its esters also show antiviral and antifungal activities.
References Yen, G. et al.: Food Chem., 79, 307 (2002); Chen, C. et al.: Mol. Nutrit. Food Res., 51, 962 (2007); Kratz, J. et al.: Mem. Inst. Oswaldo Cruz, 103, 437 (2008); Osborne, L. et al.: Infect. Immun., 33, 769 (1981);Formule :C72H2H4O5Couleur et forme :NeatMasse moléculaire :172.13n-Docosane-d46
CAS :Produit contrôléApplications n-Docosane-d46 (CAS# 260411-88-9) is a useful isotopically labeled research compound.
Formule :C22D46Couleur et forme :NeatMasse moléculaire :356.89

