Composés deutérés

Applications 1-Bromopentadecane-1,1,2,2-d4 (CAS# 1219798-87-4) is a useful isotopically labeled research compound.

Applications (+)-cis-Vincaminic Acid Ethyl-d5 Ester is labelled (+)-cis-Vincaminic Acid Ethyl Ester (V314210) which is a derivative of Vinpocetine (D448350). It has been shown that under stressed conditions, vinpocetine equilibrates with Vincaminic Acid Ethyl Ester and hydrolyzes to Apovincaminic Acid (A729250).
References Muhammad, N., et al.: J. Pharmaceu. Sci., 77, 126 (1988); Han, et al.: J. Biol. Chem., 274, 22337 (1999), O’Donnell, et al.: Pharmacol. Biochem. Behav., 63, 185 (1999);

Applications Intermediate in the biosynthesis of carotenoids
References Davidovich-Rikanati, R. et al.: Plant J., 56, 228 (2008); Puri, A. et al.: Weed Sci. 57, 482 (2009); Serino, S. et al.: J. Agric. Food Chem., 57, 8753 (2009);

Applications n-Hexadecylpyridinium-d5 Bromide (CAS# 143715-91-7) is a useful isotopically labeled research compound.

Applications Trilithium UDP-glucuronic Acid-3C1, 5N2 is an isotope labelled analog of Trisodium UDP-glucuronic Acid (T886285). Trisodium UDP-glucuronic Acid is a reactant used in the enzymatic preparation of β-glucuronides.
References Stevenson, D.E., et. al.: Collect Czech. Chem. C., 65, 117 (2000); Robotham, S.A., Brodbelt, J.S.: Biochem. Pharmacol., 82, 1764 (2011); Kren, V., et. al.: Drug Metab. Dispos., 28, 1513 (2000)

Applications Butyl Phenyl Phosphate-d9 is the deuterated form of Butyl Phenyl Phosphate (B809590), which is a phosphorus flame retardant additive.
References Sundkvist, A. M., et al.: Environ. Monit. Assess., 12, 943 (2010),

Applications Diethyl Chlorophosphate-d10 is an intermediate in the synthesis of Chlorpyrifos Oxon-d10 (C425322), which is an isotope labeled analogue of Chlorpyrifos Oxon (C425320). a metabolite of Chlorpyrifos (C425300) in human.
References Atterberry, T., et al.: Toxicol. Appl. Pharmacol., 147, 411 (1997), Karanth, S., et al.: Toxicol. Sci., 58, 282 (2000), Barter, Z., et al.: Drug Metab. Dispos., 36, 2405 (2008),

Applications tert-Butyl-1,1,1-d3 Alcohol (CAS# 33500-15-1) is a useful isotopically labeled research compound.

Applications 6-Bromo-benzoic-​2,​3,​4,​5-​d4 Acid is used for preparation of isotopologues of isoquinolinone and quinazolinone compounds as PI3K kinase inhibitors.
References Evans, C.: PCT Int. Appl. (2017), WO 2017161116 A1 20170921.

Applications A labelled metabolite of Propafenone (P757500).

Applications rac Styrene Glycol-D5 is an intermediate in the synthesis of rac Mirabegron-d5 (M364902), which is a potent bladder relaxant and reagent for diabetes remedy.

Applications n-Octyl-1,1-d2 Alcohol (CAS# 78510-02-8) is a useful isotopically labeled research compound.