Composés deutérés

Applications 1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide-d3 is the isotope labelled analog of 1,4-Dihydro-1-methyl-4-oxo-3-pyridinecarboxamide (D453415); a compound that has been shown to be one of the potential novel biomarkers of peroxisome proliferation in the rat.
References Ringeissen, S., Biomarkers, 8, 240 (2003); Shibata, K., et al.: Biosci. Biotech. and Biochem., 77, 2105 (2013)

Applications 4-Hydroxybenzophenone-d4 is an isotopic analog of 4-Hydroxybenzophenone (H829305), a metabolite of benzophenone (B204980).
References Stocklinski, A. et al. Life Sciences 26, 365(1980)

Applications n-Hexyl 4-Hydroxybenzoate-2,3,5,6-d4 (CAS# 2241800-08-6) is a useful isotopically labeled research compound. This compound has been found to be an endocrine disruptor that was found in a study involving pantyhose.
References Li, A.,et.al., Environ.Sci.Technol., 52,10812-10819,(2018);

Applications Labelled p-Phenetidine (P296300). A toxic metabolite of Phenacetin (P294580) which exhibits high renal toxicity. p-Phenetidine also reduced COX-1 and COX-2 expression in neutrophils.
References Green, C., et al.: Br. Med. J., 1, 162 (1969), Nelson, S., et al.: J. Med. Chem., 25, 753 (1982), Nicholls, A., et al.: Xenobiotica, 27, 1175 (1997),

Applications Dimethyl-d6-cyanamide (cas# 72142-88-2) is a compound useful in organic synthesis.

Applications Labelled 1,2-Bis(2,4,6-tribromophenoxy)ethane (B585425). One of the major "novel" brominated flame retardants (NBFRs) from varous polymer materials. An environmental pollutant.
References Zhu, L., et al.: Environ. Sci. Technol., 40, 3711 (2006), Qui, X., et al.: Environ. Sci. Technol., 42, 31 (2008), Stone, R., et al.: Science, 325, 1055 (2009),

Applications Isotope labelled Molinate (M486477), which is a herbicide that is used to control broad-leaved and grassy plants in rice and other crops (1,2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Nacher-Mestre, J. et al.: J. Agri. Food. Chem. 2014 Mar 12;62(10):2165-742. Sugrue, E. et al.: Appl. Environ. Microbiol. 2015 Apr;81(7):2612-24.

Applications Labelled Methylparaben (M325660). It is used as preservative in foods, beverages and cosmetics.
References Goodwin, M., et al.: Science, 203, 559 (1979),

Applications 2,4-Dichlorophenol-13C6 is the labelled analog of 2,4-Dichlorophenol (D435685). 2,4-Dichlorophenol is a chlorinated derivative of phenol and is used as an intermediate for the preparation of herbicide 2,4-dichlorophenoxyacetic acid (D435680).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhong, W., et al.: J. Hazard. Mat., 217, 286 (2012); Rowe, V.K., et al.: Am. J. Vet. Res., 15, 622 (1954), Way, J.M., et al.: Residue Rev., 26, 37 (1969)

Stability Hygroscopic
Applications Labelled Homarine (H458500). Quaternary ammonium base occurring in tissues of marine animals.
References Stein, W., et al.: J. Biol. Chem., 211, 915 (1954), Bystedt, J., et al.: J. Sci. Food Agric., 10, 301 (1959),

Applications Butanoic-d7 Acid is a deuterated version of Butanoic Acid (B692235). Butanoic Acid, is found in milk, especially goat, sheep and buffalo milk. It can be used for the preparation of various esters, such as methyl butyrate, which has pleasant aromas or tastes and thus can be used as food and perfume additives.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lupton, J. R., et al.: J. Nutrition, 134 (2), 479 (2004); Grummer, R. R., et al.: J Dairy. Sci., 74 (9),3244 (1991)

Applications 2-Amino-ethan-1,1,2,2-d4-ol is labelled Ethanolamine (E676500) which is used in the preparation of various pharmaceutical compounds and inhibitors. Substituted carboxamides are synthesized using Ethanolamine that show potent antitumor activity. Also used in the synthesis of aminoquinolones which display anti-plasmodial activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lombardo, L. et al.: J. Med. Chem., 47, 6658 (2004); Egan, T.: J. Med. Chem., 43, 283 (2000);

Applications 5-(4-Chlorobutyl)-1-cyclohexyltetrazole-d11 (cas# 1073608-19-1) is a compound useful in organic synthesis.

Applications Oxalic Acid, Disodium Salt (1,2-13c2, 99%) (cas# 260429-91-2) is a useful research chemical.

Stability Light Sensitive, Possibly Shock Sensitive
Applications Labelled 2,4-Dinitrophenol It is a precursor to other chemicals and is biochemically active, inhibiting energy (adenosine triphosphate, ATP) production in cells with mitochondria. It is also used in the synthesis of coumarins.
E0
References Harper, J. et al.: Obesity Rev., 2, 255 (2001; Yavari, I. et al.: Tetra. Lett., 39, 2391 (1998);

Applications Norfloxacin-d5 is deuterium labeled Norfloxacin (N681000), a synthetic fluoroquinolone and an antibacterial agent. Norfloxacin can be used to treat urinary tract infections.
References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Hirai, K., et al.: Antimicrob. Agents Chemother., 19, 188 (1981), Holmes, B., et al.: Drugs, 30, 482 (1985),

Applications Labeled D-Mannitol is widespread in plants and plant exudates; obtained from manna and seaweeds. D-Mannitol is used in the food industry as anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener.
References Pigman, W., et al.: The Carbohydrates, 249 (1957), Makkee, M., et al.: Chem. Commun., 930 (1980),

Applications Fenpropidin-d10 is the labeled analogue of Fenpropidin (F249470), a fungicide.
References Leroux, P. Walker, A.: Eur. J. Plant Path., 135, 683 (2013); Zhao, H., et. al.: Ecotox. Environ. Safe., 77, 52 (2012)

Applications 4-Ethylphenol-2,3,5,6-d4,OD (CAS# 340256-40-8) is a useful isotopically labeled research compound.

Stability Unstable in Solution, Hygroscopic
Applications Used in nucleophilic substitution.
References Genicot, C., et al.: Bioorg. Med. Chem. Lett., 13, 437 (2003),