Composés deutérés

Applications Butyric-2,2-d2 Acid (CAS# 19136-92-6) is a useful isotopically labeled research compound.

Applications Bis(o-cresyl) p-Cresyl Phosphate-d7 is labelled Bis(o-cresyl) p-Cresyl Phosphate (B419205), an isomer of Tricresyl phosphate (TCP) which is used as an anti-wear additive in aircraft turbine engine oil.
References De Nola, G., et al.: J. Chrmoat. A, 1200, 211 (2008)

Applications Cyclohexanol-d12 (CAS# 66522-78-9) is a useful isotopically labeled research compound.

Applications 1,3-Diphenyl-d10-urea is labelled 1,3-Diphenyl-urea which is a cytokinin compound present in fruit and vegetables. It is metabolized by a moderate halophilic Marinobacter sp.
References Sørensen, S., et al.: FEMS Microbiol. Lett., 213, 199 (2002); Campillo, N., et al.: Talanta, 116, 376 (2013)

Stability Hygroscopic
Applications Labelled 1,4-Dinitrosopiperazine. N,N'-Dinitrosopiperazine (DNP) induces nasopharyngeal carcinoma (NPC) and shows organ specificity to the nasopharyneal epithelium.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lanier, A., et al.: Cancer, 46, 2100 (1980), Waalkes, M., et al.: Carcinogenesis, 25, 133 (2004), Toth, E., et al.: Int. J. Cancer, 121, 1744 (2007),

Applications Labelled Monobutyl Phosphate (M525050). Mono and dibasic phosphate esters are anionic surfactants which have the main feature of the stability in alkaline conditions over other surfactants. They have a wide range of properties including outstanding wetting, emulsification, lubrication, coupling activity and detergency.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ramirez, F., et al.: Tetrahedron, 35, 1581 (1979);

Applications Labelled N-nitrosopiperazine derivative; shows strong nasal carcinogenicity and genotoxicity after low dose inhalation.
References Sabadie, N., et al.: Cancer Res., 40, 119 (1980), Kuchenmeister, F., et al.: Toxicol. Lett., 88, 29 (1996), Mathison, B., et al.: Mutat. Res., 380, 77 (1997),

Applications Oxalic Acid, Disodium Salt (1,2-13c2, 99%) (cas# 260429-91-2) is a useful research chemical.

Applications Acetophenone-13C6 is an intermediate in synthesizing Ibuprofen-13C6 (I140003), a labelled Ibuprofen. It is a selective cyclooxygenase inhibitor (IC50=14.9uM). Inhibits PGH synthase-1 and PGH synthase-2 with comparable potency.
References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986); Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993); Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)

Stability Hygroscopic
Applications Ethanolamine-13C2 Hydrochloride is the labeled analogue of Ethanolamine (E676500), which is used in the preparation of various pharmaceutical compounds and inhibitors. Ethanolamine-13C2, is also a 13C-labeled lipid precursor, used for the detection of phospholipid metabolism and the synthesis of phosphatidylethanolamine in T47D human breast cancer cells.
References Ronen, S. M., et al.: Magnetic Resonance Med., 25, 384 (1992); Lombardo, L. et al.: J. Med. Chem., 47, 6658 (2004); Egan, T.: J. Med. Chem., 43, 283 (2000);

Applications Formetanate-d6, Hydrochloride (cas# 1185240-24-7) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Labelled Diflufenican (D445640). (Pre and post emergence foliar absorbed herbicide for winter weed control in cereal crops; carotenoid biosynthesis inhibitor.
References Conte, E., et al.: J. Agric. Food Chem., 46, 4766 (1998),

Applications Labelled Butylparaben. An antimicrobial agent used in cosmetic products.
References Gilliland, D., et al.: J. Appl. Bacteriol., 72, 258 (1992), Routledge, E., et al.: Toxicol. Appl. Pharmacol., 153, 12 (1998), Miller, C., et al.: J. Biol. Chem., 272, 32824 (1997), Nakagawa, Y., et al.: Biochem. Pharmacol., 55, 1907 (1998),

Applications A labelled form of Pirimicarb (P508768) which is a pesticide which is useful in cannabis testing kits as a component of pesticide mixes (P698240).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Tsuchiyama, T.; et al.: Journal of Chromatography A, 1524, 233 (2017).

Applications Phenethyl Alcohol-d5 (cas# 35845-63-7) is a compound useful in organic synthesis.

Applications Isobutyric-d6 Acid is the isotope labelled analogue of Isobutyric Acid, a carboxylic acid found in vanilla. Isobutryic Acid was used as an intermediate in the synthesis of novel inhibitors of signal transducer and activators of transcription 3 signaling pathway.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhang, M.M., et al.: Euro. J. Med. Chem., 62, 301 (2013);

Applications 4-Nitrobenzoic Acid-d4 is labelled 4-Nitrobenzoic Acid (N493550) which is used in the synthesis of anti-Trypanosoma cruzi agents in the treatment of chagas disease.
References Palace-Berl, F. et al.: Bioorg, Med. Chem. Lett., 21, 5395 (2013); Zhou, L. et al.: J. Med. Chem., 56, 796 (2013);

Applications N-(4-Aminobenzoyl-d4)-β-alanine is the labeled analogue of N-(4-Aminobenzoyl)-β-alanine (A593795), a metabolite of BX661A, a therapeutic agent used in the treatment of ulcerative colitis, chemotaxis and reactive oxygen species production in polymorphonuclear leukocyctes. Inhibits lipid peroxidation in large intestinal mucosa after mesenteric ischemia/reperfusion.
References Kimura, I. et al.: Arzneimittelforschung., 48, 1007 (1998); Kumamoto, T. et al.: Jpn. J. Pharmacol., 75, 187 (1997);