Composés deutérés

Applications 1,2,3,5-Tetrachlorobenzene-d2 (CAS# 2199-74-8) is a useful isotopically labeled research compound.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications N-[2-(S)-Methyl-d3-butyryl]-4-(S)-phenylmethyl-2-oxazolidinone (cas# 1073232-99-1) is a compound useful in organic synthesis.

Applications 1-Propylamine-d3 is the isotope labelled analog of 1-Propylamine, which is used in the synthesis of pyrimidine derivatives as novel and highly potent PDE4 inhibitors. Also used in the preparation of fluorenone analogs with DNA topisomerase I inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Goto, T. et al.: Bioorg. Med. Chem., 21, 7025 (2013); Lee, C. et al.: Bioorg. Med. Chem. 21, 7125, (2013);

Applications Labelled Anisole. Anisole is used in perfumery.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Taylor, J.M., et al.: Toxicol. Appl. Pharmacol., 6, 378 (1964),

Stability Hygroscopic
Applications Tiglylcarnitine-d3 is labelled Tiglylcarnitine (T793780), a long-chain fatty ester of carnitine which is accumulated and released into the circulation, in fatty-acid oxidation defects. Pattern of Tiglylcarnitine can be diagnostic for a number of ß-oxidation defects.
References Adams, S., et al.: J. Nutrition, 139, 1073 (2009); Ventura, F., et al.: Clinica Chimica Acta, 281, 1 (1999); Pourfarzam, M., et al.: Clinical Chem,, 40, 2267 (1994); Schaefer, J., et al.: Pediatric Res., 37, 354 (1995)

Applications Intermediate in the preparation of labelled α-Carboline derivatives

Applications 4-Nitrobenzonitrile-d4 (CAS# 1219798-46-5) is a useful isotopically labeled research compound.

Applications Labelled analogue of 2-Bromopropane, a short chain alkyl halide used in organic synthesis primarily as an alkylating agent for introducing the isopropyl functional groups.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mayants, A.G. et al.: Zhur. Org. Khim., 25, 419 (1989); Miller, B. et al.: J. Org Chem., 30, 3895 (1965);

Applications Ethyl 3-(4-Fluorophenyl)-2-(2-methylpropionyl)propenoate-d6 (cas# 1185241-64-8) is a compound useful in organic synthesis.

Applications Pyridine-N-oxide-d5 (cas# 19639-76-0) is a compound useful in organic synthesis.

Applications Reagent used in the addition of labelled cyclopropane.
References Cave, C., et al.: Eur. J. Med. Chem., 25, 75 (1990), Kiyama, R., et al.: Chem. Pharm. Bull., 43, 960 (1995), Humphries, P., et al.: Bioorg. Med. Chem. Lett., 16, 6120 (2006)

Applications Labelled Dapsone intermediate.
References Tingle, M., et al.: Brit. J. Clin. Pharmacol., 30, 829 (1990), Vage, C., et al.: Toxicol. App. Pharmacol., 129, 309 (1994),

Applications α,α-Diphenyl-1-azabicyclo[2.2.2]octane-4-methanol-d10 is an intermediate in the synthesis of Umeclidinium Bromide-d5, which is considered as a potentially long-acting antimuscarinic agent.
References Cazzola, M., et al.: Pharmacol., Rev., 64, 450 (2012); Laine, D., et al.: J. Med. Chem., 52, 2493 (2009)

Applications 4-Fluoroephedrine-d3 is the labelled analogue of 4-Fluoroephedrine.

Applications Glycine-13C2,15N p-Toluenesulfonate is a by-product of an intermediate during the synthesis of m-Hydroxyhippuric Acid-13C2, 15N (H943127), a labelled m-Hydroxyhippuric Acid (H943125) which is a metabolite of caffeic and chlorogenic acids in human.
References Booth, A., et al.: J. Biol. Chem., 229, 51 (1957); Gonthier, M., et al.: Biomed. Pharmacother., 60, 536 (2006)

Applications A useful reactant in the preparation labelled Carbazeran (C175792), a phosphodiesterase inhibitor drug.

Applications Labelled 2-Bromo-1,3-propanediol (B686665) derivative. 2-Bromo-1,3-propanediol is used for isolating bases by means of Reinecke's salt.
References Dudley, H., et al.: Biochem. J., 27, 157 (1933),

Applications Chemical building block used in the synthesis of more complex structures.

Applications Aniline-13C6 Hydrochloride is an intermediate in the synthesis of Indole-3-carboxaldehyde-13C8 (I614993), the labelled version of Indole-3-carboxaldehyde (I615020) which is a tryptophan (T947200) metabolite from Streptomyces staurosporeus and it is chemical constituent from Inula wissmanniana. Indole-3-carboxaldehyde and other tryptophan metabolites play an important role in mammalian gut immune homeostasis.
References Yang, S., et al.: J. Nat. Prod., 60, 44 (1997); Cheng, X. et al.: Chem. Nat. Compd., 49, 815 (2013); Zelante, T., et al,: Immunity, 39, 372 (2013)