Composés deutérés

Applications Methyl 2-Hydroxybenzoate-3,4,5,6-d4 (CAS# 1219802-12-6) is a useful isotopically labeled research compound.

Applications 2-[2-(Methyl-d3-thio)ethyl-1,1,2,2-d4]-1H-isoindole-1,3(2H)-dione is an intermediate used in the synthesis of Lapatinib-d7 Dihydrochloride (L175807), which is a labeled Lapatinib (L175800), a reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic;Also, it is used in the preparation of 4-Aminoquinazolines as EGFR and HER-2 inhibitors.
References Kim, T.E., et al.: Drugs, 6, 886 (2003); Wood, E.R., et al.: Cancer Res., 64, 6652 (2004); Spector, N.L., et al.: J. Clin. Oncol., 23, 2502 (2005); Tung, R.: PCT Int. Appl. (2008), WO 2008024439 A2 20080228

Applications 2-Hydroxypyridine-N-oxide-d5 is the labelled analogue of 2-Hydroxypyridine-N-oxide (H953633), a reactant that is useful along wtih (S)-1-phenylethylamine and EDC·HCl for the synthesis of AZD8186, a potent and selective Inhibitor of PI3Kβ and PI3Kδ.
References B. Barlaam., et al.: J. Med. Chem., 58, 943-62 (2015);

Applications Acetamidine-d3 Hydrochloride is a useful compound in the synthesis of 3-​Chloro-​3-​methyl-​d3-​diazirine (CAS# 35496-73-2).
References Liu, M. T. H., et al.: J. Org. Chem., 45, 4515 (1980)

Applications Isotope labelled Diethylene Glycol Dimethacrylate (D444350) is an ester of acrylic acid and methacrylic acid, more commonly known as acrylates and methacrylates, are key raw materials in the coatings and printing industry, and in food packaging.
References Moore, M., et al.: Mutagenesis, 6, 77 (1991), McCarthy, K., et al.: Food Chem. Toxicol., 30, 505 (1992),

Applications L-4-Hydroxyphenyl-2,6-d2-alanine-2-d1 (CAS# 71939-39-4) is a useful isotopically labeled research compound.

Applications Anamorelin-d6 is labelled Anamorelin (A617045) which is a novel non-peptidic ghrelin mimetic and growth hormone secratogogue.
References Garcia, Jose M., et al.: Growth. Horm. IGF. Res., 19(3), 267-273 (2009)

Applications n-Nonanoic-9,9,9-d3 acid is labelled n-Nonanoic Acid (N649385) which is commonly used in conjunction with glyphosate, a non-selective herbicide, for a quick burn-down effect in the control of weeds in turfgrass. It is also used in the preparation of plasticizers and lacquers.
References Pline, W., et al.: Weed Technol., 14, 667 (2000); Frade, J., et al.: Anal. Bioanal. Chem., 395, 2167 (2009)

Applications 3-Hydroxyquinoline-d6 is labelled 3-Hydroxyquinoline (H953140) which is a chemical reagent used in the preparation cyclic peptides with an antitumor functionality. Quinoline derivative as a result of the metabolism by cytochrome P 450.
References Riego, E. et al.: Tetrahedron, 61, 1407 (2005); Kanou, M. et al.: Fund. Clin. Pharmacol., 16, 513 (2002)

Applications N-Benzoylglycine-2,2-d2 (CAS# 208928-78-3) is a useful isotopically labeled research compound.

Applications Ethyl 2,3-Dicyanopropionate-13C2 15N2, is the labeled analogue of Ethyl 2,3-Dicyanopropionate (E915950), which is an intermediate for insecticide.
References Cole, L., et al.: Pestic. Biochem. Physiol., 46, 47 (1993), Cole, L., et al.: Life Sci., 56, 757 (1995), Hosie, A., et al.: Br. J. Pharmacol., 115, 909 (1995),

Stability Light Sensitive
Applications Isotope Labelled Ethaboxam is a pesticide used as a fungicide against fungal infections in crops.
References Kim, D. et al.: Pest Manage. Sci., 60, 1007 (2004); Park, M. et al.: J. Microbiol. Biotech., 13, 43 (2003);

Applications Testosterone Hexanoate-d11 is the isotopic analog of Testosterone Hexanoate. Testosterone Hexanoate is a metabolite of testosterone(T155000), which is used in analytical studies to determine the use of anabolic steroid esters and related compounds in equine hair sample though ultra high performance liquid chromatography-tandem mass spectrometry.
References Gray, B.P., et al.: Analtica Chemica Acta, 787, 163 (2013); McKinney, A., et al.: Bioanalysis 1, 785 (2009)

Applications Ethyl-alpha,alpha-d2-benzene-d5 (CAS# 84272-90-2) is a useful isotopically labeled research compound.

Applications tert-Butyl-d9 Acrylate (CAS# 928163-00-2) is a useful isotopically labeled research compound.

Applications 2,4,6-Trimethylbenzeneamine-d11 (cas# 1126138-13-3) is a compound useful in organic synthesis.

Applications Methylcycloheptane-d3 is the isotope analog of Methylcycloheptane. It is synthesized form cycloheptanone (C989555), which is a common reagent used as the precursor for the synthesis of various pharmaceuticals including NF-κB-inducing kinase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Li, K., et al.: Bioorg. Med. Chem. Lett., 23, 1238 (2013); Hayden, M., et al.: Cell, 132, 344 (2008); Mackay, F., et al.: Annu. Rev. Immunol., 21, 231 (2003)