Composés deutérés

Applications Labelled Isohexanol (I819615). Isohexanol is used as a cosmetic compound with an antimicrobial effect especially deodorants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Benzene-1,2,3-d3 (CAS# 19467-27-7) is a useful isotopically labeled research compound.

Applications Dodecylphosphocholine (D38, 98%) (cas# 130890-78-7) is a useful research chemical.

Applications Hexadecanoic-15,15,16,16,16-d5 Acid (CAS# 285979-77-3) is a useful isotopically labeled research compound.

Applications Labelled 2,4-Diaminobutyric Acid. 2,4-Diaminobutyric Acid is a pharmacological tool and potential chiral building block. 2,4-Diaminobutyric Acid is also used as an internal standard for amino acid analysis. 2,4-Diaminobutyric Acid is also found to inhibit GABA transaminase, thus producing an elevation of GABA level, and to have an antitumor activity in vitro and in vivo against mouse fibrosarcoma cells.
References Riordan, J.F. et al.: Methods Enzymol., 47, 31 (1977); Beart, P.M. et al.: Neurscience Lett., 5, 193 (1977); Ronquist, G. et al.: J. Cancer Res. Clin. Oncol., 96, 259 (1980); Solladie-Cavallo, A. et al.: Tetrahedron Lett., 30, 6011 (1989);

Applications 1,2-Dihydrodesonide-d3 is the labeled analogue of 1,2-Dihydrodesonide (D448170), a reactant in the synthesis of 21-substituted corticosteroids which are used as topical antiinflammatory agents.
References Mitsukuchi, M., et. al.: Chem. Pharm. Bull, 37, 1795 (1989)

Applications 2-Iodopropane-d7 is the isotope labelled analog of 2-Iodopropane (I718795); a reagent used in the synthesis of 4'-O-alkyl-chitobiosyl-4-methylumbelliferone as human chitinase fluorogenic substrates.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Duivenvoorden, B.A., et al.: Carbohyd. Res., no vol., no pp. (2014, ahead of print)

Applications L-2-Aminobutyric-3,3-d2 Acid (CAS# 352431-37-9) is a useful isotopically labeled research compound.

Applications 1,3,5-Benzene-2,4,6-d3-tricarboxylic Acid (CAS# 62790-27-6) is a useful isotopically labeled research compound.

Stability Volatile
Applications Acetonitrile (15n, 98%+) (cas# 14149-39-4) is a useful research chemical.

Applications 2,6-Dimethylnaphthalene-d12 (CAS# 350820-12-1) is a useful isotopically labeled research compound.

Applications Deoxycholic Acid-24-13C (CAS# 52886-37-0) is a useful isotopically labeled research compound.

Applications Labelled Indole derivative with anticancer activity.
References Lavrenov, S. et al.: Bioorgan. Med. Chem. 18, 6905 (2010)

Applications 4-n-Octyl-d17-anisole (CAS# 1219794-56-5) is a useful isotopically labeled research compound.

Applications Cyclopropylmethanol-d3, is a labeled analogue of Cyclopropylmethanol (C988605), which is used to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A, inhibitors against phosphodiesterase 3 (PDE3). Also used in the synthesis of benzodiazapin-2-ones
References Hu, E. et al.: Bioorg. Med. Chem. Lett., 22, 6938 (2012);

Applications 2-Methylnaphthalene-D10 is a labelled analogue of 2-Methylnaphthalene (M323130). 2-​Methylnaphthalene is a polycyclic aromatic hydrocarbon (PAH) that has been used as an indicator of smoke exposure in food and packaging materials.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Johnston, J.J., et. al.: J. Agr. Food Chem., 42, 1954 (1994)

Applications 2-Nitrobiphenyl-2’,3’,4’,5’,6’-d5 (cas# 64420-97-9) is a compound useful in organic synthesis.

Applications Bis(m-cresyl) o-Cresyl Phosphate-d7 is labelled Bis(m-cresyl) o-Cresyl Phosphate (B419220), an isomer of Tricresyl phosphate (TCP) which is used as an anti-wear additive in aircraft turbine engine oil.
References De Nola, G., et al.: J. Chrmoat. A, 1200, 211 (2008)

Applications 1-Bromopentane-1,1,2,2-d4 (CAS# 1219803-61-8) is a useful isotopically labeled research compound.

Applications 2-Nitrobiphenyl-d9 (CAS# 38537-53-0) is a useful isotopically labeled research compound.

Applications tert-Butyl Methyl Ether-d12 (CAS# 284487-64-5) is a useful isotopically labeled research compound.

Applications Isotope labelled Glycerol (G598400) is used both in sample preparation and gel formation for polyacrylamide gel electrophoresis. Glycerol (5-10%) increases the density of a sample so that the sample will layer at the bottom of a gel’s sample well. Glycerol is also used to aid in casting gradient gels and as a protein stabilizer and storage buffer component.
References Bartsch, W., et al.: Arzeim.-Forsch., 26, 1581 (1976),

Applications Hydrocinnamic-alpha,alpha-d2 Acid (CAS# 19136-97-1) is a useful isotopically labeled research compound.

Applications 2,5-Dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one-d3 is the deuterated version of 2,5-Dimethyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one (D480165), which is an impurity of Alosetron (A575500) that is a serotonin 5HT3 receptor antagonist, used in treatment of irritable bowel syndrome.
References Camilleri, M., et al.: Lancet, 355, 1035 (2000); Nestorov, I., et al.: Drug Metab. Dispos., 30, 276 (2002); Lewis, D., et al.: Drug Metab. Rev., 35, 1 (2003); Tang, H., et al.: J. Pharm. Sci., 95, 1783 (2006); Gleeson, M., et al.: J. Med. Chem., 50, 101 (2007);

Applications 3-Hydroxy-2-naphthoic Acid-d6 is an intermediate used in the synthesis of Pamoic Acid-d10 (P173502), which is a labelled Pamoic Acid. Agonist of the orphan G protein-coupled receptor GPR35: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Used as an inhibitor in the real-time fluorescence enzymatic characterization study of specialized human DNA polymerases. Enzyme replacement therapy in pancreatic enzyme deficiency.
References Fonge H., et al.: Bioconjugate Chem., 18, 1924 (2007), Mayr, G.W., et al.: J. Biol. Chem., 282, 35424 (2007); Zhao, P. et al.: Mol. Pharmacol., 78, 560 (2010); Dorjsujen, D. et al.: Nuc. Acids Res., 37, e128 (2009);

Applications Ethyl N-n-Butyl-d9-carbamate (CAS# 1276197-24-0) is a useful isotopically labeled research compound.

Applications 1-Bromopentane-1,1-d2 (CAS# 77734-75-9) is a useful isotopically labeled research compound.

Applications N-Methylform-d1-amide (CAS# 26103-38-8) is a useful isotopically labeled research compound.

Applications Tetradecanoic-14,14,14-d3 Acid (CAS# 62217-71-4) is a useful isotopically labeled research compound.

Applications Methyl Methacrylate-d5 (CAS# 55935-46-1) is a useful isotopically labeled research compound.

Applications Iodoethane-1,1-d2 is a useful reagent in synthesis of 1,4-benzoquinones.
References Foland, L., et al.: J. Am. Chem. Soc., 111, 975 (1989);

Applications Fenthoxon (Dimethylphosphate-d6) is derived from Methyl Alcohol-d4 (M265107), which is the labeled analog of methyl alcohol, a common laboratory solvent used primarily in spectroscopic techniques (UV/VIS, NMR, IR). Also, it is a major metabolite of Fenthion (FEN). It is used as organophosphorus pesticides.
References Dawson, D.M. et al.: Phys. Chem. Chem. Phys., 15, 919 (2013); Buratti, F., et al.: Toxicol. Lett., 167, 245 (2006), Buratti, F., et al.: Drug Metab. Dispos., 33, 295 (2005), Buratti, F., et al.: Toxicology, 241, 33 (2007),

Applications Tetra-n-propyl-d28-ammonium Bromide (CAS# 284474-84-6) is a useful isotopically labeled research compound.

Applications N-Acetylpiperazine-d4 is labelled N-Acetylpiperazine-d4 which was used to prepare (aryl)sulfanyltriazoles with HIV-1 non-nucleoside reverse transcriptase inhibiting activities. It was also used to synthesize diphenylpyrazolecarboxamides as heat shock protein chaperone inhibitors and anticancer agents.
References Wang, Z., et al.: Bioorg. Med. Chem. Lett., 16, 4174 (2006); Brough, P., et al.: J. Med. Chem, 51, 196 (2008)

Applications Ethylene Glycol Distearate-d4 is a deuterated version of Ethylene Glycol Distearate (E917572), a component of face wash and shampoo.
References Kang, Daiping, et al.: Guangdong Huagong, 42(6), 60-62 (2015);Zhang, Kai, et al.: Guangdong Huagong, 42(19), 69-70 (2015);Yu, He, et al.: Guangdong Huagong, 40(1), 27, 45 (2013)