Composés deutérés

<p>Applications Pinacol-d12 is an intermediate in the synthesis of Isotope labelled Tebuconazole (T013002), which is an ergosterol biosynthesis inhibitor present in most pesticide formulations (1,2). Various uptake is observed in plants (3). Drinking water Contaminant Candidate List 3 - CCL 3 as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br></p>

<p>Applications 1,2,4,5-Tetramethylbenzene-d14 (CAS# 15502-50-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1-(3,5-Diacetoxyphenyl)-1-bromoethane-13C6, is the labeled analogue of 1-(3,5-Diacetoxyphenyl)-1-bromoethane (D307562), which is an intermediate for the synthesis of Resveratrol (R150000).<br>References Powell, R.G., et al.: Phytochemistry, 35, 335 (1994), Jeandet, P., et al.: J. Phytopathol., 143, 135 (1995), Mattivi, F., et al.: J. Agric. Food Chem., 43, 1820 (1995),<br></p>

<p>Applications 2,3,6-Trimethylphenol-d11 (CAS# 347841-83-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications Acetylcholine-1,1,2,2-d4 Bromide is the deuterium labelled form of Acetylcholine Bromide (A172073), which is an endogenous neurotransmitter at cholinergic synapses.<br>References Kobayashi, M., et al.: Adv. Physiol. Sci., 22, 319 (1981); Hulme, C., et al.: Biophys. J., 91, 2371 (2006);<br></p>

<p>Applications Phthalic-13C Acid is an isotope labelled version of Phthalic Acid (P384480), an organic reagent used to synthesize phthalates.<br>References Duchowicz, P.R., et al.: Bioorg. Med. Chem., 16, 7944 (2008);di Luccio, E., et al.: Biochem., 47, 4039 (2008);Lopez, Z., et al.: App. Microbiol. Biotechnol., 78, 739 (2008);Hong, Y., et al.: Toxicol. Lett., 184, 139 (2009)<br></p>

<p>Applications Indole-4,5,6,7-d4 is a labelled analogue of Indole (I577320), which can be used in perfumes and in the synthesis of tryptophan. It is also an intermediate in synthesizing Indoleacetic Acid-13C6 (I577343), which has the potential to be used in anti-cancer therapy in conjunction with horseradish peroxidase (HRP).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kawano, T. et al.: Gen. Hypo. 60, 664 (2003);<br></p>

<p>Applications Isotope labelled Propyl Paraben Sulfate (P838355) is the sulfate conjugate of Propyl Paraben (P838285), an antimicrobial agent used in cosmetic products.<br>References Kim, D.H., et al.: Biol. Pharma. Bull., 17, 1326 (1994);<br></p>

<p>Applications It is a stable isotopically labelled analog of Tasimelteon (T007740) which is a novel drug, used in the treatment of non-24 hour sleep-wake disorder. It helps to correct the circadian rhythm disorder often seen in patients who are visually impaired.<br>References Lahon, J. et al.: World. J. Pharm. Res., 3, 1521 (2014)<br></p>

<p>Applications Ammonium Formate-d5 (CAS# 65387-23-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications Benzene-1,2,3,5-d4 (CAS# 14941-52-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications Iodoacetic Acid-d3 (CAS# 1219799-36-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications Tetracosanoic-12,12,13,13-d4 Acid (CAS# 1219794-59-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications N-Acetylglycine-13C2,15N is a labelled derivative of N-Acetylglycine (A178260(P)), which is a derivative of Glycine (G615990). Glycine is a useful intermediate for synthesizing rac 3-O-Methyl DOPA (M303805), which is an impurity of Levodopa.<br>References Tabar, et al.: Pharmacol. Biochem. Behav., 33, 139 (1989), De Souza Silva, et al.: J. Neurochem., 68, 233 (1997), Feigin, A., et al.: Neurology, 57, 2083 (2001), Perera, A., et al.: J. Labelled Comp. Radiopharm., 46, 389 (2003)<br></p>

<p>Applications Adenosine-2-d1 (CAS# 109923-50-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications Dicyclohexyl Carbonate-d22 is the isotope labelled analog of Dicyclohexyl Carbonate (D438505); a reagent in the synthesis of colon specific reduction sensitive polymers for pharmaceuticals.<br>References Schacht, E. and Wilding, I.: PCT Int. Appl. WO 9610994 A1 19960418. Apr 18, 1996<br></p>

<p>Applications Hexanenitrile-6,6,6-d3 (CAS# 1219805-03-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,4-Di(methyl-d3)-naphthalene has been used in the preparation of di(trideuteriomethyl)naphthalene derivatives. 1,4-Di(methyl-d3)-naphthalene is a labeled analogue of 1,4-Dimethylnaphthalene (D476380), a polycyclic aromatic hydrocarbon (PAH) that has been found to retard the development of epidermoid carcinomas in hamster buccal pouch and alter the genes associated with the maintenance of a G1/S phase block possibly through the induction of the cell cycle inhibitors KRP1 and KRP2 in potatoes.<br>References Dizabo, P., et. al.: J. Labelled Compd., 2, 272 (1966); Malament, D.S., Shklar, G.: Carcinogenesis, 2, 723 (1981); Campbell, M.A., et. al.: Fuct. Interg. Genomics, 12, 533 (2012); Andrysik, Z., et. al.: Mutat. Res-Fund. Mol. M., 714, 53 (2011)<br></p>

<p>Applications (±)-2-Chlorobutane-d9 (CAS# 175540-77-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications Ethylene Glycol Dilaurate-d4 is a deuterated version of Ethylene Glycol Dilaurate (E917476), a pearling agents for cosmetics.<br>References Onozaki, T., et al.: Journal of SCCJ, 15, 38-44 (1981)<br></p>

<p>Applications Tridecanoic-2,2-d2 Acid (CAS# 64118-44-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications o-Tolyl-d7 Isocyanate (CAS# 1219802-73-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications Ethyl 2-Bromo-2-methyl-d3-propionate-3,3,3-d3 (CAS# 64768-38-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 1,3-Diethylbenzene-d14 (CAS# 1219803-40-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications Diethyl Oxalacetate-13C4 is an intermediate used in the synthesis of (O845032), which is labelled form of Oxaloacetic Acid (O845030) which is a four carbon dicarboxylic acid that is an intermediate in the citric acid cycle and glucogenesis. It has been shown to inhibit succinate dehydrogenase.<br>References Zeylemaker, W.P. et al.: Biochim. Biophys. Acta Enzymol., 132, 210 (1967); Dalla-Betta, P. et al.: Int. J. Mol. Sci., 10, 2809 (2009);<br></p>

<p>Applications 1,3-Di-iso-propylbenzene-d18 (CAS# 1398065-59-2) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Cholesten-3-one-3,4-13C2 (CAS# 82938-09-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications Ethyl 4-Isocyanatobenzoate-2,3,5,6-d4 (CAS# 1219802-91-1) is a useful isotopically labeled research compound.<br></p>

<p>Applications Glyceryl-d5 Trioctadecanoate (CAS# 55256-03-6) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Fluorobenzyl-d6 Chloride (CAS# 1219804-13-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications Chlorobenzene-3,4,5-d3 (CAS# 59164-11-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications 2-Ethyl-3,4,5,6-tetrahydropyridine Hydrochloride-d3 is the isotope labelled analog of 2-Ethyl-3,4,5,6-tetrahydropyridine Hydrochloride (E926330); a compound that is produced by lactic acid bacteria (LAB) and can cause mousy off-flavor in wines.<br>References Snowdon, E.M., et al.: J. Agr. Food Chem., 54, 6465 (2006); Costello, P.J., et al.: J. Agr. Food Chem., 50, 7079 (2002); Craig, J.T., et al.: Am. J. Enol. Viticult., 35, 46 (1984)<br></p>