Composés deutérés

Applications Dimethyl Hexanedioate-2,2,5,5-d4 (CAS# 76785-05-2) is a useful isotopically labeled research compound.

Applications 6-Hydroxy Nicorandil-d4 is the isotope labelled analog of 6-Hydroxy Nicorandil (H948550); a metabolite of the antianginal Nicorandil (N398500).
References Frydman, A., et al.: Am. J. Cardiol., 63, 25J (1989); Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008); Sudo, H., et al.: Biol. Pharm. Bull., 31, 2079 (2008); Iida, S., et al.: Brit. J. Clin. Pharmacol., 66, 352 (2008); Eguchi, Y., et al.: Ther. Res., 29, 316 (2008)

Stability Light Sensitive
Applications Labelled 2-Ethylhexyl 2,3,4,5-Tetrabromobenzoate (E918780). 2-Ethylhexyl 2,3,4,5-Tetrabromobenzoate is a flame retardant.
References Gouteux, B., et al.: Environ. Sci. Technol., 42, 9039 (2008), Lee, E., et al.: J. Toxicol. Sci., 2010, 35, 535 (2010), Arp, H., et al.: J. Environ. Monit., 13, 505 (2011),

Applications N-Methyl-d3-N-nitroso-p-toluenesulfonamide is the labeled version of Diazald; Diazomethane precursor.
References Takizawa, et al.: J. Pharm. Soc. Jpn., 70, 490 (1950)

Applications N-Hexanoylglycine-2,2-d2 (CAS# 1256842-52-0) is a useful isotopically labeled research compound.

Applications The four-center reactions of alkanol-alkoxide negative ions with alkyl ethers and ortho-acetates. An ion cyclotron resonance study.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Phenol-2,4,6-d3,OD (CAS# 80441-87-8) is a useful isotopically labeled research compound.

Applications N-Octanoylglycine-2,2-d2 (CAS# 1219805-51-2) is a useful isotopically labeled research compound.

Applications D-4-Hydroxyphenyl-d4-alanine-2,3,3-d3 (CAS# 1426174-46-0) is a useful isotopically labeled research compound.

Applications 2,2',3,5',6-Pentachlorobiphenyl-13C12 is the labeled analogue of 2,2',3,5',6-Pentachlorobiphenyl (P237935), an environmental neurotoxicant that promotes synaptogenesis through ryanodine receptor-dependent miR132 upregulation.
References Lesiak, A., et. al.: J. Neurosci., 34, 717 (2014)

Applications 1,3-Dimethoxybenzene-2,4,5,6-d4 (CAS# 362049-44-3) is a useful isotopically labeled research compound.

Applications 2-Hydroxyethyl Nortadalafil-d4 is the isotope labelled analog of 2-Hydroxyethyl Nortadalafil (H942245); a derivative of Tadalafil (T004500) which is a compound used for the treatment of erectile dysfunction. Also a phosphodiesterase 5 inhibitor.
References Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003); Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005); Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005)

Applications 4,4-Bis(4-aminophenylsulfonyl)-azobenzene-d16 is the isotope labelled analog of 4,4-Bis(4-aminophenylsulfonyl)-azobenzene. 4,4-Bis(4-aminophenylsulfonyl)-azobenzene is synthesized from dapsone (D193250), an antibacterial used in the treatment of dermatitis herpetiformis.
References Francis, J., et al.: Br. J. Pharmacol., 5, 565 (1950), Uetrecht, J., et al.: Clin. Dermatol., 7, 111 (1989); Reszka, K., et al.: Chem. Res. Toxicol., 22, 1137 (2009), Santos, J., et al.: Bioorg. Med. Chem., 17, 3795 (2009), Varma, M., et al.: J. Med. Chem., 52, 4844 (2009),

Applications 3-Bromoaniline-d4 (cas# 81395-17-7) is a compound useful in organic synthesis.

Applications O-Methyl Phosphorodichloridothioate-d3 is an intermediate used in the synthesis of Parathion-methyl-d6 (P192227), a derivative of Parathion (P192220), an organophosphate insecticide used on cotton, rice and fruit trees.
References Sykes, M., et al.: J. Agri. Food. Chem., 61, 4205 (2013); Sipes, N.S., et al.: Chem. Res. Toxicol., 26, 878 (2013);