Composés deutérés

Applications DL-Tryptophan-d8 (CAS# 1233395-85-1) is a useful isotopically labeled research compound.

Applications Erythromycin Ethyl Succinate-13C,d3 is the deuterated form of Erythromycin Ethyl Succinate (E649985), which is a derivative of Erythromycin (E649950), an antibiotic.
References Koch, W.L., et al.: Anal. Profiles Drug Subs., 8, 157 (1979); Serisier, D. et al.: J. Am. Med. Assoc., 309, 1206 (2013);

Applications 2-[(Tetrahydro-2H-pyran-2-yl)oxy]ethanol-d4 is an intermediate used in the synthesis of Roxithromycin-d7 (R700852), which is a semisynthetic labelled Erythromycin derivative. Antibacterial.
References Jones, R.N., et al.: Antimicrob. Agents Chemother., 24, 209 (1983), Barry, A.L., et al.: Eur. J. Clin. Microbiol., 5, 536 (1986), Grassi, C., et al.: Chemioterapia, 6, 41 (1987),

Applications 4-n-Pentylphenol-d16 (CAS# 1219805-40-9) is a useful isotopically labeled research compound.

Applications Heptanoic-7,7,7-d3 Acid (CAS# 156779-04-3) is a useful isotopically labeled research compound.

Applications 8-Bromo-3,7-dihydro-3-methyl-7-(1-methylethyl)-1H-purine-2,6-dione-d7, is the labeled analogue of (B683490), which is a substituted derivative of Xanthine (X499950).
References Mueller, C. et. al: Handbook Exp. Pharmacol. 200,151(2011)

Applications 2,4,5-Triamino-6-hydroxypyrimidine-13C2 Sulfate Salt is an intermediate used in the preparation of labelled 2-Amino-6,8-dihydroxypurine Hydrochloride (A604920). A labelled substituted 5-aminopyrimidines with antioxidative activity.
References Prochazkova, E. et al.: Free Radical Res., 46, 61 (2011); Lin, S. et al.: J. Med. Chem., 22, 741 (1979)

Applications N-(4-Aminobenzoyl-d4)-β-alanine is the labeled analogue of N-(4-Aminobenzoyl)-β-alanine (A593795), a metabolite of BX661A, a therapeutic agent used in the treatment of ulcerative colitis, chemotaxis and reactive oxygen species production in polymorphonuclear leukocyctes. Inhibits lipid peroxidation in large intestinal mucosa after mesenteric ischemia/reperfusion.
References Kimura, I. et al.: Arzneimittelforschung., 48, 1007 (1998); Kumamoto, T. et al.: Jpn. J. Pharmacol., 75, 187 (1997);

Applications Heptanoic-6,6,7,7,7-d5 Acid (CAS# 1219803-98-1) is a useful isotopically labeled research compound.