Composés deutérés

Applications 2-Hydroxypyridine-N-oxide-d5 is the labelled analogue of 2-Hydroxypyridine-N-oxide (H953633), a reactant that is useful along wtih (S)-1-phenylethylamine and EDC·HCl for the synthesis of AZD8186, a potent and selective Inhibitor of PI3Kβ and PI3Kδ.
References B. Barlaam., et al.: J. Med. Chem., 58, 943-62 (2015);

Applications 1-Bromooctane-d17 (CAS# 126840-36-6) is a useful isotopically labeled research compound.

Applications A labelled methoxime derivative as internal standard for Prostaglandin assays by gas chromatography-mass spectrometry.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Herold, D.A., et al.: Prostaglandins, 33, 599 (1987),

Applications Anamorelin-d6 is labelled Anamorelin (A617045) which is a novel non-peptidic ghrelin mimetic and growth hormone secratogogue.
References Garcia, Jose M., et al.: Growth. Horm. IGF. Res., 19(3), 267-273 (2009)

Applications Hexanedioic-d8 Acid Dihydrazide (CAS# 1202865-37-9) is a useful isotopically labeled research compound.

Applications n-Tetradecyl-1,1-d2 Alcohol (CAS# 169398-02-1) is a useful isotopically labeled research compound.

Applications Nexturastat A-d5 is the isotope labelled analog of Nexturastat A (N391500); a potent and selective histone deacetylase 6 (HDAC6) inhibitor that shows potential antiproliferative effects against melanoma cells.
References Bergman, J.A., et al.: J. Med. Chem., 55, 9891 (2012)

Applications L-Alanine-3,3,3-d3-N-t-BOC acts as a reagent for the synthesis of amino acid derivatives that serves as precausors for peptides synthesis.
References Lankiewicz, L., et al.: J. Chem. Soc., Perkin Transactions, 17, 2503 (1994)

Applications 3-Hydroxyquinoline-d6 is labelled 3-Hydroxyquinoline (H953140) which is a chemical reagent used in the preparation cyclic peptides with an antitumor functionality. Quinoline derivative as a result of the metabolism by cytochrome P 450.
References Riego, E. et al.: Tetrahedron, 61, 1407 (2005); Kanou, M. et al.: Fund. Clin. Pharmacol., 16, 513 (2002)

Applications Dimethyl Heptanedioate-2,2,6,6-d4 (CAS# 120811-82-7) is a useful isotopically labeled research compound.

Applications Ethyl 2,3-Dicyanopropionate-13C2 15N2, is the labeled analogue of Ethyl 2,3-Dicyanopropionate (E915950), which is an intermediate for insecticide.
References Cole, L., et al.: Pestic. Biochem. Physiol., 46, 47 (1993), Cole, L., et al.: Life Sci., 56, 757 (1995), Hosie, A., et al.: Br. J. Pharmacol., 115, 909 (1995),

Applications N-(Carboxymethyl)-N,N,N-trimethyl-d9-ammonium Chloride (CAS# 285979-85-3) is a useful isotopically labeled research compound.

Applications Sodium Hexadecanoate-d31 (CAS# 467235-83-2) is a useful isotopically labeled research compound.

Applications o-Xylene-alpha,alpha,alpha,alpha',alpha',alpha'-d6 (CAS# 25319-54-4) is a useful isotopically labeled research compound.