Halogénures organiques

Applications (R,R)-Ethambutol Dihydrochloride shows antitumor properties when complexed with platinum. Also an isomer of Ethambutol (E889800), an antibacterial (tuberculostatic).
References Coluccia, M. et al.: Anticanc. Res., 11, 281 (1991); Wilkinson, et al.: J. Med. Chem., 5, 835 (1962), Kulig, et al.: Diss. Pharm. Pharmacol., 23, 463 (1971), Lee, C.S., et al.: Anal. Profiles Drug Subs., 7, 231 (1978)

Applications 6-Bromo-1-hexanol is a useful synthetic intermediate. 6-Bromo-1-hexanol is used as a reagent in the preparation of nitric oxide-donating analogues of Sulindac (S699215), a non-steroidal anti-inflammatory drug that has the ability to prevent colon cancer.
References Nortcliffe, A., et al.: Bioorg. Med. Chem., 22, 756 (2014); Pasricha, P., et al.: Gastroenterology, 109, 994 (1995); Yamamoto, Y., et al.: J. Biol. Chem., 274, 27307 (1999)

Applications 2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2,3,4-Trichlorophenylboronic acid (cas# 352530-21-3) is a useful research chemical.

Applications 2-Chloroethyl Ethyl Sulfide is used as a reagent in the synthesis of furfuryl xanthines as adenosine receptor antagonists. It is also used as a reagent in the synthesis of methoxypropyl xanthines as putative A2B receptor antagonists.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Balo, M.C., et al.: Bioorg. Med. Chem., 17, 6755 (2009); Nieto, M.I., et al.: Bioorg. Med. Chem., 17, 3426 (2009)

Applications Methyltriphenylphosphonium Bromide is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.
References Selassie, C.D. et al.: J. Med. Chem., 33, 1914 (1990); Venkatachalam, M.A et al.: Kidney Int., 49, 449 (1996);

Applications 1-Bromo-9-(tert-butyldimethylsilyloxy)nonane is used in the preparation of Fulvestrant (F862500) intermediate.
References Liu, W., et al.: Faming Zhuanli Shenqing (2014), CN 103965280 A 20140806

Applications 1,3-Dichlorobenzene was used to study the effect of solvent vapor pressure on the vertical nanowire of C60 molecules. It can be detected in environmental samples using an advanced Fourier transform infrared spectroscopy-attenuated total reflectance (FTIR-ATR) sensor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kim, J.: ACS Nano, 7, 9122 (2013); Lu, R., et al.: Scientific Reports, 3, 2525 (2013)

Stability Hygroscopic
Applications 2-Chloro-1,4-phenylenediamine Sulfate

Applications 3-Chloro-2-hydroxypropyltrimethyl ammonium chloride is used in the preparation of multifunctional cationized cotton fabric based on TiO2 nanomaterials.
References Farouk, A., et la.: Int. J. Biol. Macromolecules, 61, 230 (2013);

Applications 2-Chloronicotinic Acid is used in the preparation of 4-thiazolidinone derivatives and Schiff bases displaying antimicrobial activity.
References Patel, N. et al.: Saudi Pharm. J., 18, 129 (2010); Patel, N. et al.: J. Sci. Islam Repub. Iran., 21, 121 (2010);

Applications 1-Bromo-2-phenoxybenzene can be used for quantification for trace polybrominated di-Ph ether in biota samples from electronic waste recycling area.
References Liang, S., et.al., Ziran Kexue Ban, 29, 511-517, (2009);

Applications 1-Bromocyclopentyl 2-Chlorophenyl Ketone is a reactant in the dehydrohalogenation of axial 6-bromoketamine III and is also an intermediate in the synthesis of S-(-)-Norketamine (N692060).
References Parcell, R., et al.: J. Org. Chem., 45, 5055 (1981);

Applications 10-Bromo-1-aminodecane, Hydrobromide (cas# 24566-82-3) is a compound useful in organic synthesis.

Stability Hygroscopic
Applications Trimethylsulfonium Chloride is used as a reagent in the preparation of spirastrellolide A Me ester via Suzuki coupling, Yamaguchi lactonization, Julia-Kocienski olefination, bond cleavage, and ozonolysis, its antitumor activity, and SAR with truncated variants.
References Arlt, A., et al.: Chem. Eur. J., 19, 3596 (2013)

Applications 1-Cyclopropyl-2-(2-fluorophenyl)-2-hydroxy-ethanone is a useful synthetic intermediate in the synthesis of Prasugrel (P701150, HCl); an antiplatelet agent.
References Wiviott, S.D., et al.: Circulation, 116, 2923 (2007); Xu, X., et al. Faming Zhuanli Shenqing. CN 102718642 A 20121010. Oct 10, 2012; Wang, G., et al. Faming Zhuanli Shenqing. CN 101402556 A 20090408. Apr 8, 2009

Applications Ethyl 4-Bromo-2-(methoxyimino)-3-oxobutyrate is an intermediate used in the synthesis of some thiophene analogs as anti-inflammatory agents.
References Pillai, A., et al.: Bioorg. Med. Chem., 13, 1275 (2005)

Applications 3-((2-Nitro-4-(trifluoromethyl)-phenyl)amino)propane-1,2-diol, (cas# 104333-00-8) is a useful research chemical.

Stability Light Sensitive
Applications Dibromoacetonitrile is a carcinogenic nitrogenous disinfection byproduct. Dibromoacetonitrile in drinking water was linked to oral cavity cancer in rats and forestomach cancer in mice. In addition, Dibromoacetonitrile may cause oxidative damage in rat brain.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Guo, Z., et al.: Chem. Eng. J. 306, 1180 (2016); Krasner, S. W., et al.: Environ. Sci. Technol. 50, 9583 (2016); Natl Toxicol Program Tech Rep Ser. 544, 1 (2010); Klattisaksiri, P., et al.: Water Res 98, 160 (2016); Sayed, R. H., et al.: Environ Toxicol Pharmacol. 34, 849 (2012)

Applications 3,4,5-Trichlorocatechol has found to be toxic to marine algal.
References Ertuerk, M.D., et. al.: J. Mol. Graph. Model., 38, 90 (2012)

Applications 1,1-Dibromoethane is a useful reagent for setereoselective synthesis of (+)-phorboxazole A via Petasis-Ferrier rearrangement. It is also used for preparation of olefinic enol ether.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Smith, A., et al.: J. Am. Chem. Soc., 123, 10942 (2001); Fujimura, O, et al.: J. Org. Chem., 59, 4029 (1994);

Applications 2-Chloroethylamine Hydrochloride is used as a reagent in the synthesis of 6-desfluoroquinolones as potential anti-HIV drugs. Also used as a reagent in the synthesis of ellipticine derivatives as anticancer agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sancineto, L., et al.: Bioorg. Med. Chem., 22, 4658 (2014); Mori, R., et al.: Eur. J. Med. Chem., 82, 16 (2014)

Stability Light Sensitive
Applications 3-Chlorocyclohexene (cas# 2441-97-6) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2,7-Dibromo-9H-fluorene is a useful building block for organic synthesis.

Applications 3,5-Difluorobenzylamine is a useful reagent for reductive amination.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cantrill, S., et al.: J. Org. Chem., 66, 6857 (2001);

Applications Methyl 2,3-dichlorobenzoate

Applications A styrene derivative used in the preparation of bisphosphane ligand and phenanthroline-based functionalized macrocycles and catenanes.
References Goek, Y. et al.: Tetrahedron: Asymmetr., 21, 2768 (2010); Megiatto, J. & Schuster, D.: New J. Chem., 34, 276 (2010); Megiatto, J. & Schuster, D.: J. Am. Chem. Soc., 130, 12872 (2008)

Applications Epichlorohydrin is used as a solvent for natural and synthetic resins, gums, cellulose esters and ethers, paints, varnishes, nail enamels and lacquers, cement for Celluloid. Also, it is used as stabilizer.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Smyth, H.F., et al.: J. Ind. Hyg. Toxicol., 30, 63 (1948),

Stability Hygroscopic
Applications 2-Amino-5-Ethylphenol Hydrochloride (cas# 149861-22-3) is a useful research chemical.

Applications 9-Hydroxyfluorene is a wake promoting agent and is considered as the next generation anti-narcolepsy drug. It is also a potential environmental carcinogen.
References Dunn, D., et al.: Bioorg. Med. Chem. Lett., 22, 3751 (2012); Clark, J., et al.: Environ. Res., 117, 132 (2012); Li, F., et al.: Environ. Toxicol. Phar., 32, 373 (2011)

Applications 2-[2-(2,2,2-Trifluoroethoxy)phenoxy]-ethanol, is used in the preparation of hydroxy(aminomethyl)pyridine derivatives.
References Elworthy, T.R., et al.: J. Med. Chem., 40, 2674 (1997)

Applications 4-Aminomethyl Benzamidine Dihydrochloride is a small molecule CXCR4 antagonist.
References Zhan, Weiqiang, et al.: J. of Med. Chem., 50(23), 5655-5664 (2007)

Applications 2-Chloro-5-thiazolecarboxylic Acid (C411465) was studied as one of the metabolites of thiamethoxam, clothianidin, and dinotefuran in mice.
References Ford, K., et al.: Chem. Res. Toxicol., 19, 1549 (2006);

Applications Chlorobenzene is a halogenated benzene used in chemical toxicity QSAR research for agricultural pollution.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Fielden, M., et al.: Curr. Opin. Drug Discovery Dev., 9, 84 (2006), Jonker, M., et al.: Carcinogenesis, 30, 1805 (2009), Jennen, D., et al.: Toxicol. Sci., 115, 66 (2010),

Applications It is used in a new method for conjugation of carbohydrates to proteins using an aminooxy-thiol heterobifunctional linker.
References Tietze, L., et al.: Bioconjugate Chem., 2, 148 (1991), Peeters, C., et al.: Infect. Immun., 60, 1826 (1992), Brask, J., et al.: J. Pept. Sci., 6, 290 (2000),

Stability Moisture Sensitive
Applications n-Octyl Chloroformate is a chemical reagent used in the synthesis of surfactants derived from N-alkoxycarbonyl amino acids. Also used n the preparation of piperazinyl-glutamate-pyridines used as orally bioavailable P2Y12 antagonists in platelet aggregation.
References Kawase, T. et al.: J. Oleo. Sci., 59, 191 (2010); Parlow, J. et al.: Bioorg. Med. Chem. Lett., 19, 4657 (2009);

Applications 1,3-Dichloropropan-2-one O-Benzyl-oxime (cas# 188125-86-2) is a compound useful in organic synthesis.

Applications Dibromoformaldoxime is a reagent that undergoes cycloaddition with alkynes to prepare substituted 3-bromo-isoxazoles in high yield.
References Chiarino, D., et al.: J. Heterocyclic Chem., 24, 43 (1987); De Amici, M., et al.: J. Org. Chem., 54, 2646 (1989); Castelhano, A., et al.: 16, 335 (1988).

Applications Methyl 2-Nitro-4-(trifluoromethyl)benzoate has been used in the synthesis of isoxazolinone antibacterial agents, using nitrogen as a replacement for the stereogenic center of the molecule. Also used in the preparation of benzo[b]azepines as inhibitors of cholesterol ester transfer.n
References Snyder, L. et al.: Bioorg. Med. Chem. Lett., 14, 4735 (2004);

Applications Chloramine-T Trihydrate is used as a safe and convenient electrocyclisation (oxidizing) agent in the preparation of 8-chloro-[1,2,4]triazolo[4,3-a]pyrazine derivatives.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mal, S., et al.: Tetrahedron Lett., 56, 2896-2901 (2015)

Applications Bromocyclobutane
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications N-Alkyl(C12-16)-N-benzyl-N,N-dimethylammonium chloride, tech. (cas# 68424-85-1) is a useful research chemical.

Applications Used for preparation of substituted indazole amides as glucokinase activators.
References Perles, J., et al.: J. Mater. Chem., 14, 2683 (2004),

Applications 2,4,6-Tribromophenol a reagent used in industrial synthesis of compounds and pharmaceuticals. It is used in the synthesis of anti-HIV candidates. Identified as a metabolic impurity of industrial chemical runoff in humans and wildlife.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ludovici, D. et al.: Bioorg. Med. Chem. Lett., 11, 2229, (2001); Hovander, L. et al.: Arch. Env. Cont. Toxicol., 42, 105 (2002);

Stability Light Sensitive
Applications An intermediate in the synthesis of Terbinafine (T107500).

Applications Iodosobenzene (cas# 536-80-1) is a useful research chemical.

Applications 1-Bromo-2-octyne, is an intermediate in the synthesis of pinolenic acid. This compound is also used in preparation of substituted indoles though Rh-catalyzed amino-Claisen rearrangement.
References Saito, A., et al.: J. Org. Chem., 74, 1517 (2009)

Applications Diamino-5-phenylthiazole Hydrobromide is an phenylthiazole derivative used in the preparation of antiallergic and antiinflammatory agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ban, M. et al.: Bioorg. Med. Chem., 6, 1069 (1998);

Applications Used to protect alcohols during organic synthesis.
References Shen, H., et al.: J. Med. Chem., 53, 2666 (2010), Qiang, L., et al.: Bioorg. Med. Chem. Lett., 20, 836 (2010),

Applications 1-Chloroethyl Cyclohexyl Carbonate is a genotoxic impurity used in the synthesis of Candesartan Cilexetil. an angiotensin II receptor antagonist.
References Kakasaheb, N. et al.: Int. J. Pharm. Sci., 6, 370 (2014); Mao, Y. et al.: Heterocycles, 81, 1503 (2010);

Applications Anticonvulsant against audiogenic convulsion.
References Kim, K., et al.: J. Med. Chem., 51, 5330 (2008), Ruel, R., et al.: Bioorg. Med. Chem. Lett., 18, 2985 (2008),

Applications Propacetamol HCl (cas# 66532-86-3) is a useful research chemical.

Applications 2-Chloro-1,3-benzothiazole is used in the synthesis of CBTs which are good building blocks for bioluminescent compounds for imaging.
References Hauser, J. et al.: Bell. J. Org. Chem., 12, 2019 (2016);

Applications 4-chlorocatechol was a major degradation product of 4-chloro-2-aminophenol (4C2AP)1. The degradation of 4-chlorocatechol was catalyzed by cphA-I enzyme2.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Quintelas, C., et al.: Environ. Sci. Pollut. Res. Int., 20, 1374 (2013); Costa, F., et al.: Biodegradation, 23, 81 (2012)

Applications Heptafluorobutyranilide (cas# 336-61-8) is a compound useful in organic synthesis.

Stability Volatile
Applications Pentafluoropropionic acid (Perfluoropropionic acid) was used in the analysis of gentamicin with Gemini column by liquid chromatographic (LC) methods. It was also used to prepare [(R)-(amino)(oxo)(fluorophenyl)butyl]tetrahydro(fluoroethyl)-1,2,4-triazolo[4,3-a]pyrazine using (fluoro)propanoic acid.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Manyanga, V., et al.: J. Pharm. Biomed. Analysis, 45, 257 (2007); Kim, D., et al.: J. Med. Chem., 48, 141 (2005)

Applications 2-Cyclopentyl-4-chlorophenol, Technical Grade (cas# 13347-42-7) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Nonanoyl Chloride is used in the synthesis of immunosuppressants involving 2-aminoethanols and aminopropane-1,2-diols. Also used in the synthesis of Vanilloids with antinociceptive and antiinflammatory compounds.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kiuchi, M. et al.: J. Med. Chem., 43, 2946 (2000); Janusz, J. et al.: J. Med. Chem., 36, 2595 (1993);

Applications 2,3,5,6-Tetrachlorotoluene is a tetra-chlorinated derivative of toluene that is often used as a reference standard.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Chloroform is generally used in NMR spectroscopy as a solvent, in trimethylsilane solution. It has been used an an anaesthetic due to its action on the central nervous system.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Johansson, J. et al.: Photochem. Photobiol., 77, 89 (2003); Fryczkowski, R. et al.: Synth. Metals, 166, 14 (2013); Guo, S. et al.: Tetra. Asymm., 24, 480 (2013);

Stability Hygroscopic
Applications Hydrazine hydrochloride (cas# 2644-70-4) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Bromonitromethane is used in the preparaton of [2,3-d]pyrimidines as inhibitors of Lck which can be used in the treatment of diseases where T-cell proliferation is unwanted. It is also used in the synthesis of isoxazoline N-oxides.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References DiMauro, E. et al.: Bioorg. Med. Chem. 17, 2305 (2007); Kunetsky, R. et al.: Org. Lett., 5, 4907 (2003);

Applications α,α-Dichlorotoluene is a chemical reagent used in organic synthesis through activation of the chlorinated methyl group. Pesticide component.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Siwek, A. et al. ChemCatChem., 9, 839 (2017);

Stability Hygroscopic
Applications Semicarbazide Hydrochloride is a metabolite of Nitrofuran (N493840), a minor antimicrobial used in veterinary medicine affecting semicarbazide-sensitive amine oxidase (SSAO) activity (1). Semicarbazide may be found in from nitrofuran residues in honey extracts (2) as well as milk from dairy cows (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.Environmental contaminants; Food contaminants; Heat processing contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Elliott J. et al.: J Pharm Pharmacol. 1989 Jan;41(1):37-41. 2. Tribalat L. et al.: Anal Bioanal Chem. 2006 Dec;386(7-8):2161-8. 3. Chu, P. et al.: J. Agric. Food Chem. 2007 Feb:55(6);2129-2135

Applications O-2-Propynylhydroxylamine hydrochloride (cas# 21663-79-6) is a useful research chemical.

Applications 2,3,5,6-Tetrachlorophenol is used in the study of the toxicity of halogenated phenols.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References He, G., et al.: Procedia Eng., 43, 204 (2012)

Stability Hygroscopic, Light Sensitive
Applications 6-Hydroxydopamine is a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson's disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. 6-Hydroxydopamine induces apoptosis in PC12 cells.
References Soto-Otero, R. et al.: J. Neurochem., 74, 1605 (2000); Fujita, H. et al.: Brain Res., 1113, 10 (2006); Breese, G.R. et al.: 174, 313 (1970);

Stability Moisture Sensitive
Applications Pentafluorobenzoyl Chloride is a useful analytical reagent in the derivatization amphetamines as well as other primary amines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Koster, E. et al.: Analyst, 127, 598 (2002);

Applications Nonafluoro-1-butanesulfonyl Fluoride is a useful perfluorinated compound (PFC) used in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zimmer, R., et al.: J.Prakt. Chem., 340, 274 (1998)

Applications A fundamental chemical building block commonly used in organic synthesis of more complex structures.A benzoic acid analogue that showed antifungal activity against strains of Aspergillus flavus, Aspergillus fumigatus and Aspergillus terreus, causative agents of human aspergillosis, in in vitro bioassays.
References Rep, M., et al.: J. Biol. Chem., 275, 8290 (2000), Jaeger, T., et al.: Biofactors, 27, 109 (2006), Kim, J., et al.: Fungal Biology, 114, 817 (2010),

Stability Volatile
Applications 1,1,1,3,3,3-Hexafluoro-2-propanol effects the native state of proteins, denaturing them as well as stabilizing the α-helical conformation of unfolded proteins and polypeptides.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hirota, N. et al.: Prot. Sci., 6, 416 (1997);

Applications p-Trifluoromethylphenyl is used in the synthesis of P2Y1 antagonists and antithrombotic agents. Also, used in the synthesis of potent myeloid cell leukemia inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chao, H. et al.: J. Med. Chem., 56, 1704, 2013; Friberg, A. et al.: J. Med. Chem., 56, 15 (2013);

Applications 1,2,3-Tribromobenzene is an organic chemical reagent used in the synthesis of cis-trikentrin B as well as in the synthesis of diphenyl ethers for induction of CYP1A via the receptor mediated pathway.
References Chen, G. et al.: Env. Sci. Tech., 35, 3749 (2001); Chandrasoma, N. et al.: Tetra. Lett., 54, 913 (2013);

Applications 1,5-Dibromopentane is used as an alkylating agent in organic synthesis. 1,5-Dibromopentane is also used as a reagent to synthesize benzo[b]xanthone derivatives, compounds that have potential anticancer activity.
References Luo, L., et al.: J. Serb. Chem. Soc., 78, 1301 (2013); Royer, G. & Klotz, I.: J. Am. Chem. Soc., 91, 5885 (1969)

Applications Chlorprothixene
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 3,5-Diiodothyronamine Hydrobromide is an intermediate in the synthesis of Thyronamines and related analogues.
References Hart, M. E., et al.: J. Med. Chem., 49, 1101 (2006);

Applications 2,5-Dichlorophenol is an intermediates in the manufacture of more complex chemical compounds such as fungicides.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wang, F., et al.: Bull. Enviro. Contamin. Toxicol., 89, 316 (2012); Zhong, W., et al.: J. Hazard. Mat., 217, 286 (2012);

Applications Isotope labelled Trifluoroacetic Acid used as a solvent in a variety of organic synthesis and chemical processes. Used in the synthesis of anticancer agents as well as phospholipase D inhibitors.
E0
References Scott, S. et al.: Nat. Chem. Biol., 5, 108 (2009); Minko, T. et al.: Cancer. Chemother. Pharmacol., 50, 143 (2002);

Applications 1,2,4-Tribromobenzene is a compound commonly used in organic synthesis reactions. 1,2,4-Tribromobenzene is hepatotoxic to rats, and is also toxic to humans.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Dodd, D., et al.: Int. J. Toxicol., 31, 250 (2012); Szymanska, J.: Arch Toxicol., 72, 97 (1998)

Applications An intermediate for the preparation of Citalopram.

Applications 2-bromo-6-chlorophenol (cas# 2040-88-2) is a useful research chemical.

Applications 2-(Bromomethyl)benzonitrile is an intermediate in the synthesis of Alogliptin (A575425), an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Antidiabetic agent.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lai, Z., et. al.: Eur. J. Med. Chem., 83, 547 (2014); Lynn, F., et al.: Diabetes, 50, 1004 (2001); Trumper, A., et al.: J. Endocrinol., 174, 233 (2002); Vollmer, K., et al.: J. Clin. Endocrinol. Metab., 94, 1379 (2009)

Applications 1,1-Dichloro-2-propanone is a disinfection byproduct in drinking water. It may cause bladder cancer and other adverse health effects.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Farre, M., et al.: Water Sci. Tehnol., 12, 573 (2012); Catherine, M., et al.: Water Res., 47, 3231 (2013); Neale, P., et al.: Environ. Sci. Technol., 46, 10317 (2012)

Applications 2,2,2-Trichloroacetamide was an aliphatic halogenated DBP precursor identified in drinking water treatment; a pollutant.
References Zhang, Y., et al.: J. Environ. Sci. (Beijing, China), 58, 322 (2017)

Impurity Adamantane Impurity 3
Applications 1-Ethyl-3-bromoadamantane have been used in the synthesis of 1-adamantyloxyalkanols. Adamantane Impurity 3
References Reznikov, A.N., et al.: Russ. J. Org. Chem., 46, 1741 (2010); Henkel, J.G., et al.: J. Med. Chem., 25, 51 (1982);

Applications 2-Chloroethyl Methyl Ether is used as a reagent in the synthesis of Piperonyl Methoxyethyl Ether (P490475); a selective inhibitor of the cytochrome P450-dependent monooxygenase from the housefly.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Motoyama, N., et al.: Rev. Pestic. Toxicol., 1, 173 (1991)

Applications 2-Phenylacetimidamide hydrochloride (cas# 2498-46-6) is a useful research chemical.

Stability Moisture Sensitive
Applications Benzoyl Chloride is used in the manufacturing of dye intermediates.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Glotzbach, C. et al.: J. Org. Chem., 78, 4410 (2013); Coskun, A. et al.: J. Am. Chem. Soc., 127, 10464 (2005);