Halogénures organiques

<p>Applications 1-Chlorotetradecane is a useful synthetic intermediate. It is an intermediate used to prepare Dimethyldimyristyl ammonium chloride (D472560), a surfactant.<br>References Cipiciani, A., et al.: Austr. J. Chem., 44, 1505 (1991);<br></p>

<p>Applications 1-Bromobenzene, is used as a general reagent in palladium-catalyzed reactions and in the synthesis of Grignard reagents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Miyaura, N. et al.: Synth. Commun., 11, 513 (1981); Nahm, S. et al.: Tetra. Lett., 22, 3815 (1981);<br></p>

<p>Applications 4-[2,2-dichloro-1-(4-hydroxyphenyl)ethenyl]phenol (cas# 14868-03-2) is a useful research chemical.<br></p>

<p>Applications 2-Amino-5-chlorobenzenesulfonic Acid can be used as reactant/reagent in determination of the dissociation constants of some newly synthesized arylhydrazones of indane-​1,​3-​dione.<br>References Mahmudov, K. T.: Azerbaidzhanskii Khimicheskii Zhurnal, 4, 92 (2011)<br></p>

<p>Applications trans-3-(2-Chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl-cyclopropanecarboxylic Acid is a reagent used in the synthesis of indanyl insecticides.<br></p>

<p>Applications 3-Chlorophenol is a halophenol with antifungal activity. 3-Chlorophenol is commonly used as a building block in the preparation of variety of biologically active compounds. Studies suggest that 3-Chlorophenol can be used in the regeneration of vegetal activated carbons.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gershon, H. et al.: Monatsh. Chem., 126, 1161 (1995); Dranca, I.: Environ. Eng. Man. J., 5, 203 (2006);<br></p>

<p>Stability Volatile<br>Applications 1,1,1,3,3,3-Hexafluoro-2-propanol effects the native state of proteins, denaturing them as well as stabilizing the α-helical conformation of unfolded proteins and polypeptides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirota, N. et al.: Prot. Sci., 6, 416 (1997);<br></p>

<p>Stability Hygroscopic<br>Applications Omeprazole Sulfide Hydrochloride is a metabolite of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.<br>References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)<br></p>

<p>Applications 4-Pyridylethylmercaptan, Hydrochloride (cas# 6298-11-9) is a compound useful in organic synthesis.<br></p>

<p>Applications 2,4,6-Tribromophenyl Acetate (cas# 607-95-4) is a compound useful in organic synthesis.<br></p>

<p>Applications Octachlorocyclopentene (cas# 706-78-5) is a useful research chemical.<br></p>

<p>Applications 3-Aminophthalic acid hydrochloride (cas# 6946-22-1) is a useful research chemical.<br></p>

<p>Applications 2-Butanoylsulfanylethyl(trimethyl)azanium Chloride is a metabolite analyzed from the bark of Weinmannia trichosperma Cav. (Cunoniaceae), which has been used to treat chronic diarrhea, inflammation, and wounds.<br>References Barrientos, R., et al.: Front. Pharmacol., 11, 780 (2020)<br></p>

<p>Applications 4-Chlorobenzenethiol is a reagent used in the synthesis of small-molecule inhibitors of the protein geranylgeranyltransferase Type I (GGTase-I), acting as anti-tumor agents. Also is used in the synthesis of β-sulfanyl carbonyl compounds via Michael addition.<br>References Ranu, B. et al.: Tetrahedron, 60, 4183 (2004); J. Med. Chem., 43, 2310 (2000);<br></p>

<p>Applications o-tert-Butyl-α-chlorotoluene is a useful research reagent for the competitive chloromethylation of alkylbenzenes.<br>References Takezawa, T., et al.: Nippon Kagaku Kaishi 6, 1047 (1989); Hu, Y. L., et al.: J. Chil. Chem. Soc., 55, 97 92 (2010); Pinnell, R. P., et al.: Tetrahedron Lett., 25, 3511 (1984)<br></p>

<p>Stability Hygroscopic<br>Applications DOTA-NHS-ester Hexafluorophosphate TFA Salt is used as a reagent in the preparation of metal or radiometal-labeled-urea- and carbamate-based PSMA inhibitors for PSMA-targeted imaging and radiotherapy.<br>References Ray, S., et al.: PCT Int. Appl. (2015), WO 2015171792 A1 20151112<br></p>

<p>Applications 3-Benzoylbenzyl Bromide (cas# 22071-24-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 1-[4-(2-Chloroethoxy)phenyl]-2-phenylethanone (cas# 19561-95-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 4-Chloro-3-nitrobenzotrifluoride is a chemical reagent used in chemical synthesis such as trifluoromethoxylated aniline derivatives.<br>References Hojczyk, K. et al.: Angew. Chem. Int. Ed., 53, 14559 (2014);<br></p>

<p>Applications Butylamine Hydrochloride is a miscellaneous reagent used in the synthesis of benzamides for the synthesis of various drugs and polymers.<br>References Bantreil, X. et al.: Eur. J. Org. Chem., 2015, 416 (2015);<br></p>

<p>Applications 2-Amino-3,5-dibromobenzoic acid (cas# 609-85-8) is a useful research chemical.<br></p>

<p>Applications 9-(2-Chloro-ethyl)-9H-purin-6-ylamine (cas# 19255-48-2) is a compound useful in organic synthesis.<br></p>

<p>Applications 1,2,4-Trichlorobenzene is a solvent in various organic chemical reactions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Legrand, Y. et al.: J. Am. Chem. Soc., 125, 15789 (2003); Aver'yanov, V. et al.: Kin. Cata., 43,175 (2002);<br></p>

<p>Applications 1,2,4-Tribromobenzene is a compound commonly used in organic synthesis reactions. 1,2,4-Tribromobenzene is hepatotoxic to rats, and is also toxic to humans.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dodd, D., et al.: Int. J. Toxicol., 31, 250 (2012); Szymanska, J.: Arch Toxicol., 72, 97 (1998)<br></p>

<p>Applications Ethylenebis(tetrabromophthalimide) is an additive fire retardant that is added to a polymer mixture to produce a blend. Ethylenebis(tetrabromophthalimide) is used in high impact polystyrene (HIPS), polyethylene, polypropylene, thermoplastic polyesters, polyamide, ethylene propylene-diene terpolymers (EPDM rubbers) and other synthetic rubbers, polycarbonate, ethylene copolymers, ionomer resins, epoxies, and textile treatments.<br>References Clausen, E., et al.: Anal. Chem., 327, 297 (1987);<br></p>

<p>Applications tert-Butyldiphenylchlorosilane is used to synthesize interphenylene phenyloxazoles, compounds that have antagonistic activity against thromboxane receptors which can be used for treatment of circulatory disorders, angina and stroke.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hadjipavlou–Litina, D. &amp; Kontogiorgis, C.: Int. Elect. J. Mol. Des., 1, 300 (2002); Misra, R., et al.: Bioorg. Med. Chem. Lett., 2, 937 (1992)<br></p>

<p>Applications Hydrazine Dihydrochloride (cas# 5341-61-7) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 2,2-Difluoro-3-hydroxy-(3-pyridyl)propionic Acid (cas# 887354-54-3) is a compound useful in organic synthesis.<br></p>

<p>Stability Very Moisture Sensitive<br>Applications Chlorotriphenylstannane is used in the synthesis of nanoparticles which bear triamide ligands.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shariatinia, Z. et al.: Beil. J. Nanotech., 4, 94 (2013);<br></p>

<p>Applications Magnesium Chloride Hexahydrate is used in magnesium replacement therapy for those deficient in magnesium. Effective anaesthetic for cephalopods.<br>References Iezhitsa, I. et al.: Nutr. Neurosci., 14, 10 (2011); Culloty, S. et al.: Aquaculture., 107, 249 (1992);<br></p>

<p>Applications 4-Fluoro-3-nitrobenzotrifluoride is an intermeidate used in the synthesis of 2-nitro-4-trifluoromethylphenylhydrazine, derivatization reagent for 1,2-diol compounds and oxo-steroids and [3-(2-nitro-4-trifluoromethylphenyl)aminophenyl]dihydroxyborane, derivatization reagent for 1,2-diol compounds and oxo-steroids.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Higashi, T., et al.: Anal. Sci., 18, 1301 (2002); Caci, E., et al.: Am. J. Physiol. Lung Cellular and Molecular Physiology, 285, L180 (2003)<br></p>

<p>Applications Ethyl 3-bromopropionate<br></p>

<p>Applications Combinations of Bis(trichloromethyl)sulfone, (Hexachlorodimethyl sulfone) and 1,2-Dibromo-2,4-dicyanobutane are shown to have synergistic antimicrobial properties. The synergistic compounds may be used together with a third microbiocide to enhance the compound’s effectiveness against a wide variety of bacteria, molds, and yeasts and other microorganisms.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pearl, G., et al.: Curr. Top Med. Chem., 1, 247 (2001), Casalegno, M., et al.: Chem. Res. Toxicol., 18, 740 (2005), Toropov, A., et al.: Bioorg. Med. Chem., 14, 2779 (2006),<br></p>

<p>Applications p-Chloroaniline Hydrochloride<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Moisture Sensitive<br>Applications n-Undecanoyl Chloride is an analog of Heptanoyl Chloride (H281235), which is used in the synthesis of novel class of 2-Aminopyrimidines as CDK1 and CDK2 inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Samanta, R., et al.: Org. Lett., 14, 5518 (2012); Sabbah, M., et al.: Bioorg. Med. Chem., 20, 4727 (2012)<br></p>

<p>Applications (R,R)-Ethambutol Dihydrochloride shows antitumor properties when complexed with platinum. Also an isomer of Ethambutol (E889800), an antibacterial (tuberculostatic).<br>References Coluccia, M. et al.: Anticanc. Res., 11, 281 (1991); Wilkinson, et al.: J. Med. Chem., 5, 835 (1962), Kulig, et al.: Diss. Pharm. Pharmacol., 23, 463 (1971), Lee, C.S., et al.: Anal. Profiles Drug Subs., 7, 231 (1978)<br></p>

<p>Applications 2,4-Dichloro-3,5-dinitrobenzotrifluoride is a reagent used in the synthesis of kinesin spindle protein inhibitors. Potential use as an alternative to neurotoxic MT inhibitors.<br>References Dong, J. et al.: Eur. J. Med. Chem., 70, 427 (2013);<br></p>

<p>Applications Fluorobenzene, is an aryl fluorinated building block used in various chemical synthesis. Fluorobenzene is a useful solvent for highly reactive species.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Flood, D. T., Org. Synth.; Coll., 2, 295 (1943); Perutz, R. N., et al.: Compeh. Organometallic Chem., 1, 725 (2007);<br></p>

<p>Applications 1-Bromo-2-chlorobenzene is a reagent in the preparation of arylpiperidines and aryltetrahydropyridines as 5-HT2C agonists.<br>References Conway, R.J., et al.: Bioorg. Med. Chem. Lett., 22, 2560 (2012)<br></p>

<p>Applications 3-[3-(trifluoromethyl)phenyl]propan-1-amine (cas# 104774-87-0) is a useful research chemical.<br></p>

<p>Applications 6-Bromo-3H-isobenzofuran-1-one<br></p>

<p>Applications 3-(Trifluoromethyl)benzenepropanal (cas# 21172-41-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Di-tert-butyldichlorosilane (cas# 18395-90-9) is a useful research chemical.<br></p>

<p>Applications An antimalarial; antirheumatic; lupus erythematosus suppressant. It is a COVID19-related research product.<br>References Yarden, Y., et al.: Nature, 323, 226 (1986), Seifert, R., et al.: J. Biol. Chem., 264, 8771 (1989), Gahl, W., et al.: Mol. Genet. Metab., 76, 234 (2002), Card, J., et al.: Toxicol. Sci., 75, 169 (2003),<br></p>

<p>Applications Benzylamine Hydrochloride (cas# 3287-99-8) is a useful research chemical.<br></p>

<p>Applications 3-Acetyl-3-chlorodihydrofuranone (cas# 2986-00-7) is a compound useful in organic synthesis.<br>References Litvak, M., et al.: Pharm. Chem. J., 39, 500 (2005), Thomas, A., et al.: Bioorg. Med. Chem. Lett., 18, 2206 (2008),<br></p>

<p>Applications 2-[(Chloroacetyl)amino]benzoic Acid is used to prepare (thiazolyl)arylquinazolinone derivatives via cyclocondensation.<br>References Giri, R., et al.: Eur. J. Med. Chem., 44, 2184 (2009);<br></p>

<p>Applications 1-Chlorododecane is used as a reagent in the chemical modification of zein to reduce the brittleness of zein films.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shi, K., et al.: J. Agr. Food Chem., 59, 56 (2011)<br></p>

<p>Applications Phenyl N-​(2-​Chloro-​4-​hydroxyphenyl)​carbamate is a reagent used in the prepartion of quinoline-carboxamide compounds including Lenvatinib (L329400), an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors.<br>References Wang, N. et al.: Faming Zhuanli Shenqing (2017), CN 106632033 A 20170510.<br></p>

<p>Applications 1-Bromo-9-(tert-butyldimethylsilyloxy)nonane is used in the preparation of Fulvestrant (F862500) intermediate.<br>References Liu, W., et al.: Faming Zhuanli Shenqing (2014), CN 103965280 A 20140806<br></p>

<p>Applications epi-5-Fluoro ADB is an analog of fluoronatied ADB-PINACA an analog of AKB48 in which the adamantyl group has been replaced with 1-amino-3,3-dimethyl-1-oxobutan-2-yl (ADB). epi-5-Fluoro ADB is a synthetic cannabinoid. Synthetic Cannabinoids<br>References Uchiyama, N., et al.: Forensic Toxicol., 30, 114 (2012)<br></p>

<p>Applications (1R,3S)-3-Aminocyclopentanol Hydrochloride is used to for the preparation of 6-Aminopyridin-3-ylthiazoles as a method of treating or ameliorating a syndrome, disorder or disease related rheumatoid arthritis or psoriasis.<br>References Goldberg, S., et al.: PCT Int. Appl., 793pp (2017)<br></p>

<p>Applications 1-Chloro-2-nitrobenzene is a useful synthetic intermediate. It was used in the synthesis of 1-hydroxybenzotriazole derivatives. Reaction of 1-chloro-2-nitrobenzene with dinitrogen pentoxide in dichloromethane is strongly catalysed by H-Faujasite-720.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fathalla, M., et al.: J. Chem. Soc. Pak., 33, 324 (2011); Claridge, R., et al.: J. Chem. Soc. Perkin Trans. II, 9, 1815, (1999)<br></p>

<p>Applications 1-Chloro-2-(α-chlorophenylmethyl)benzene is used as a reagent in the synthesis of bifonazole analogs which have antibacterial and antifungal activities. It is also used in the preparation of diphenylpiperazine N-type calcium channel inhibitors.<br>References El Hage, S., et al.: Arch. Pharm., 344, 402 (2011); Pajouhesh, H., et al.: Bioorg. Med. Chem. Lett., 20, 1378 (2010)<br></p>

<p>Stability Moisture Sensitive<br>Applications A phosphorylating agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sartori: Chem. Rev., 48, (1951), Nachmansohn, et al.: Adv. Enzymology, 12, 259 (1951)<br></p>

<p>Applications α-Chlorobenzyl 4-Fluorophenyl Ketone is derived from Benzyl 4-Fluorophenyl Ketone (B279785), which is used in preparation and evaluation of 2,3-diarylpyrazines and quinoxalines as selective COX-2 inhibitors.<br>References Singh, S. et al.: Bioorg. Med. Chem., 12, 1881 (2004);<br></p>

<p>Applications tert-butyl N-[3-(chlorosulfonyl)propyl]carbamate (cas# 1196153-59-9) is a useful research chemical.<br></p>

<p>Applications 2-(Bromomethyl)benzonitrile is an intermediate in the synthesis of Alogliptin (A575425), an oral antihyperglycemic agent that is a selective inhibitor of the enzyme dipeptidyl peptidase-4 (DPP-4). Antidiabetic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lai, Z., et. al.: Eur. J. Med. Chem., 83, 547 (2014); Lynn, F., et al.: Diabetes, 50, 1004 (2001); Trumper, A., et al.: J. Endocrinol., 174, 233 (2002); Vollmer, K., et al.: J. Clin. Endocrinol. Metab., 94, 1379 (2009)<br></p>

<p>Applications 2,4-DINITROBENZYL BROMIDE (cas# 3013-38-5) is a useful research chemical.<br></p>

<p>Stability Very Very Moisture Sensitive<br>Applications Dichlorotriphenylphosphorane is a reagent used in the synthetic preparation of sulfonamides. Also used to prepare O-alkylated benzamides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chen, Y. et al.: RSC. Adv., 5, 4171 (2015); Prabhakaran, P. et al.: Tetrahedron, 68, 4485 (2012);<br></p>

<p>Applications N-(4-Chlorobenzyl)-1-(5-nitrothiophen-2-yl)methanamine is an analogue of GSK 4112 (G797700) which is a synthetic ligand for REV-ERBα, a member of the nuclear receptor superfamily that functions as a receptor for the porphoryin heme. GSK 4112 mimics the action of heme acting as agonist and suppresses the expression of REV-ERBα target genes involved in gluconeogenesis.<br>References Kojetin, D. et al.: ACS Chem. Biol., 6, 131 (2011); Grant, D. et al.: ACS Chem. Biol., 5, 925 (2010)<br></p>

<p>Applications DOTA-4AMP, is a macrocyclic ligand used for preparation of magnetic resonance imaging contrast agents.<br>References Sun, X, et al.: Huaxue Tongbao, vol. 75, :21-26 (2012);<br></p>

<p>Stability Moisture Sensitive<br>Applications Tetrabutylammonium Difluorotriphenylsilicate is used as a reagent in the synthesis of (S)-N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine ((-)-P7C3-S243); a neuroprotective chemical with improved druglike properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Naidoo, J., et al.: J. Med. Chem., 57, 3754 (2014)<br></p>

<p>Applications 1,3,5-TRIMETHYL-1,3,5-TRIS(3,3,3-TRIFLUOROPROPYL)CYCLOTRISILOXANE (cas# 2374-14-3) is a useful research chemical.<br></p>

<p>Applications 1H,1H,2H,2H-Perfluorododecan-1-ol is a fluorotelomer alcohol (FTOH) often detected in indoor dust.<br>References Fraser, A.J., et al.: Environ. Int., 60, 128 (2013); Xu, Z., et al.: Sci. Toral Environ., 443, 485 (2013); Shoeib, M., et al.: Environ. Sci. Technol., 45, 7999 (2011)<br></p>

<p>Applications 2,6-Dibromo-4-fluorophenol<br></p>

<p>Stability Moisture Sensitive<br>Applications 4,5-Dichlorophthalic anhydride<br></p>

<p>Applications Tert-butyl 4-Aminobutanoate Hydrochloride is used as a substance in the prevention of drug-induced memory impairement by immunopharmacotherapy.<br>References Treweek, J. B., et al.: J. Med. Chem., 51, 6866 (2008)<br></p>

<p>Applications 3-(4-Bromophenyl)-2-propen-1-ol (cas# 105515-33-1) is a useful reagent for the preparation of aryltetralin cyclic ether lignans.<br>References Xiang, J. C., et al.: Angew. Chem. Int. Ed., 59, 21195 (2020)<br></p>

<p>Applications Fluoro phosphates useful as surfactants, surface treating agents, leveling agents.<br></p>

<p>Applications 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-Heptadecafluoro-10-iododecane<br></p>

<p>Applications 2-Chloro-2,3-Dimethyl Butane (cas# 594-57-0) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Hygroscopic<br>Applications Cyclopropylmethyl Bromide is a reagent used in the synthesis of human dihydroorotate dehydrogensase inhibitors which are based on azole scaffolds. In addition it is used in the preparation of ([11C]CMDC) for PET imaging of mGlur2 which has been a proposed target in the treatment of schizophrenia.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sainas, S. et al.: Eur. J. Med. Chem., 129, 287 (2017); Ma, Y. et al.: Bioorg. Med. Chem., 25, 1014 (2017);<br></p>

<p>Applications Tetrabutylammonium Chloride is used in the preparation of polypyrrole coatings with self healing properties for iron corrosion.<br>References Nakayama, M. et al.: Electrochem. Comm., 9, 1145 (2007);<br></p>

<p>Applications 2,2-Dichloro-1-(2,4-dichlorophenyl)ethanone is used in the synthesis of acid chloride phenylhydrazones in a broad-spectrum anthelmintic series.<br>References Rector, D. et al.: J. Med. Chem., 24, 532 (1981);<br></p>

<p>Stability Hygroscopic<br>Applications 1H,1H,2H,2H-Perfluorohexanol is used in the synthesis of polymer coatings with controlled surface topography. As well used in the preparation of star polymers as fluorous nanocapsules for the encapsulation and release of perfluorinated compounds.<br>References Szczepanski, C. et al.: ACS Mat. Int., 9, 3063 (2016);<br></p>

<p>Applications 2,4,5,6-Tetrachloro-m-xylene, is an intermediate for the synthesis of pesticides and metabolites. It can also be used for the preparation of Quinol nitrates.<br>References Suzuki, H., et al.: J. Chem. Soci. Comm., 51 (1957); Snyder, J. L., et al.: Anal. Chem., 64, 1940 (1992);<br></p>

<p>Applications An intermediate for the preparation of Brimonidine.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Impurity Acemetacin EP Impurity A / Bezafibrate EP Impurity B<br>Applications A benzoic acid analogue that showed antifungal activity against strains of Aspergillus flavus, Aspergillus fumigatus and Aspergillus terreus, causative agents of human aspergillosis, in in vitro bioassays. It is used as a preservative.<br>References Rep, M., et al.: J. Biol. Chem., 275, 8290 (2000), Jaeger, T., et al.: Biofactors, 27, 109 (2006), Kim, J., et al.: Fungal Biology, 114, 817 (2010),<br></p>

<p>Stability Hygroscopic<br>Applications Diphenyltin Dichloride belongs to a class of organotin compounds that are commonly used as pesticides, fungicides, and plastic additives. It is an environmental pollutant with potential antitumor activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Khosa, R.L. et al.: Sci. Cult., 35, 637 (1969); Hamasaki, T. et al.: Mutat. Res. Gen. Toxicol. Test., 300, 265 (1993); Peng, J.: Yaox. Xueb., 29, 406 (1994)<br></p>

<p>Stability Hygroscopic<br>Applications 2,6-Difluoroaniline is an important chemical in the sythesis technology for high-efficiency insecticide.<br>References Xiong, G.-I. et al.: ANh. Nong. Kex., 36, 9848 (2008);<br></p>

<p>Applications 1,2,3-Tribromobenzene is an organic chemical reagent used in the synthesis of cis-trikentrin B as well as in the synthesis of diphenyl ethers for induction of CYP1A via the receptor mediated pathway.<br>References Chen, G. et al.: Env. Sci. Tech., 35, 3749 (2001); Chandrasoma, N. et al.: Tetra. Lett., 54, 913 (2013);<br></p>

<p>Applications N,N-Dimethylbenzeneethanamine is used in the synthesis of squalene synthase inhibitors.<br>References Spencer, T. et al.: J. Org. Chem., 64, 807 (1999); Shechter, I. et al.: Bioorg. Med. Chem. Lett., 6, 2585 (1996);<br></p>

<p>Applications 1-Chloroethyl Cyclohexyl Carbonate is a genotoxic impurity used in the synthesis of Candesartan Cilexetil. an angiotensin II receptor antagonist.<br>References Kakasaheb, N. et al.: Int. J. Pharm. Sci., 6, 370 (2014); Mao, Y. et al.: Heterocycles, 81, 1503 (2010);<br></p>

<p>Stability Moisture Sensitive<br>Applications Pentafluorobenzoyl Chloride is a useful analytical reagent in the derivatization amphetamines as well as other primary amines.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Koster, E. et al.: Analyst, 127, 598 (2002);<br></p>

<p>Stability Hygroscopic<br>Applications N-(2-Chloroethyl)-1,2-ethanediamine Dihydrochloride is an analog of 2-(2-Aminoethylamino)ethanol (A608990); a reagent used in the synthesis of various pharmacologically active compounds and functional groups. Also used in the synthesis of antitumor anthracene-diones and antitumor DNA intercalators. More recently used in the synthesis of ionic liquids with various thermal, dielectric and catalytic properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bair, K. et al.: J. Med. Chem., 33, 2385 (1990); Krapcho, A. et al.: J. Med. Chem., 37, 828 (1994); Karadag, A. et al.: J. Mol. Liq., 177, 369 (2013)<br></p>

<p>Applications 2-Amino-4-chlorobenzenethiol is used as reagent in the synthesis of several organic compounds including that of MHY908 which is an inhibitor of melanogenesis and can potentially be used in the prevention and treatment of pigmentation disorders. Also used in the synthesis of γ-lactam analogs of prostaglandin E2 which may act as EP4 agonists.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Park, M., et al.: Arch. Pharm. Res., 38, 505 (2015); Kambe, T., et al.: Bioorgan. Med. Chem., 20, 3502 (2012);<br></p>

<p>Applications Di-β,β'-Chloroethylphosphoric Acid, is a dialkyl hydrogen phosphates, that can undergo the electrophilic trifluor- omethylation to produce trifluoromethyl phosphates in order to increase the lipophilicity of functional groups.<br>References Santschi, N., et al.: J. Fluorine Chem., 135, 83 (2012);<br></p>

<p>Applications 1-(4-Amino-3-chlorophenyl)ethanone (cas# 6953-83-9) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications Tris(1,1,3-tribromo-2,2-dimethylpropyl) phosphate (cas# 19186-97-1) is a useful research chemical.<br></p>