Halogénures organiques

Please enquire for more information about N-(2-chloro-5-nitrophenyl)-3-chloropropanamide including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Applications 1,3-Dichloroacetone (cas# 534-07-6) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications o-phenetidine hydrochloride (cas# 89808-01-5) is a useful research chemical.

Applications Benzenesulfonyl Chloride is used in the synthesis of cecloprotoberberine derivatives as antitumor agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Li, Y. et al.: Eur. J. Med. Chem., 68, 463 (2013);

Applications N-(4-bromo-2-thienyl)-carbamic Acid 1,1-Dimethylethyl Ester, is an intermediate for the synthesis of bicyclic inhibitors of ROCK protein kinsae.
References Hahmann, C. et al.: Cell. Mol. Life Sci., 67, 171 (2010);

Applications 4-(2-Aminoethyl)-1,3-dihydro-2H-indol-2-one Hydrochloride, can be used for the synthesis of Ropinirole (R641000), which is an antiparkinsonian agent. It is also a selective dopamine D2-receptor agonist.
References Eden, R.J., et al.: Pharmacol. Biochem. Behav., 38, 147 (1991), Rascol, O., et al.: Mov. Disord., 13, 39 (1998),

Applications 2,2,2-Trichloroethyl Chloroformate is a general reagent for the demethylation of tertiary methylamines. It is used as a reagent in the synthesis of a series of piperazine ureas as fatty acid amide hydrolase inhibitors and analgesics. Also used as a reagent in the synthesis of pyrazolo[3,4-d]pyrimidine derivatives as GPR119 agonists.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Montzka, T.A., et al.: Tetrahedron Lett., 15, 1325 (1974); Kono, M., et al.: Bioorg. Med. Chem., 22, 1468 (2014); Gillespie, P., et al.: Bioorg. Med. Chem. Lett., 24, 949 (2014)

Applications 4-Hydroxybenzamidine, Hydrochloride (cas# 38148-63-9) is a compound useful in organic synthesis.

Applications 5-Bromo-1-pentene (cas# 1119-51-3) is a compound useful in organic synthesis.

Applications 1,1'-Oxybis[2,3,4-tribromo-benzene] is a polybrominated diphenyl ether (PBDE) used as a flame retardant.
References Rayne, S., et al.: Environ. Int., 32, 575 (2006); Jakobsson, K., et al.: Chemosphere, 46, 709 (2002)

Applications 2,6-Diiodophenol is a useful reactant in organic synthesis.
References Gebara, Karimi S., et al.: Tetrahedron Let., 52(22), 2849-2852 (2011);Lv, Chunjie, et al.: Org. Let., 20(7), 1919-1923 (2018)

Applications [(Methoxy)methyl]triphenylphosphonium Chloride is used in the synthesis of Cephalotaxine (C261050), an antiviral and antitumor agent. Also used in the synthesis of Taxol A fragment.
References Sells, M., et al.: J. Virol., 62, 2836 (1988), Kaneko, S., et al.: J. Clin. Microbiol., 27, 1930 (1989), Baba, Y., et al.: Bioorg. Med. Chem., 13, 5164 (2005), Romero, M., et al.: Antiviral Res., 68, 75 (2005); Hirai, S. et al.: Tetrahedron Lett., 54, 1888 (2013); Xing, P. et al.: Synth., 45, 596 (2013);

Stability Unstable in DMSO, Methanol
Applications 2,6-Dimethylbenzyl Bromide is a reactant used in the synthesis of spinosyns which display insecticidal activity. Also used in the preparation of pyridazine derivatives as glutamate transporter EAAT2 activators.
References Oliver, M. P. et al.: J. Agric. Food. Chem., 63, 5571 (2015); Xing, X. et al.: Bioorg. Med. Chem. Lett., 21, 5774 (2011);

Applications 2-Acetamido-5-fluorophenylboronic acid, pinacol ester

Applications N-(2-acetyl-1-benzofuran-3-yl)-2-chloroacetamide (cas# 855715-46-7) is a useful research chemical.

Applications An intermediate for the preparation of Brimonidine.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications TFAN reacts with reducing oligosaccharides in the presence of sodium cyanoborohydride to give aminoalditol derivatives, useful for linking to proteins or solid matrices. Treated this way, reducing oligosaccharides were easily separated by HPLC.
References Wong, H., et al.: J. Med. Chem., 17, 785 (1974), Kallin, E., et al.: Glycoconjugate Journal, 3, 311 (1986)

Applications N-Benzoylcarbonylaminoacetamidine Hydrochloride (cas# 50850-19-6) is a compound useful in organic synthesis.
References Kitagawa, H., et al.: Bioorg. Med. Chem. Lett., 17, 4982 (2007),

Applications (S)-2,3-dihydroxypropyl 4-Chlorobenzoate is a useful synthetic intermediate.

Applications 1,2-Diamino-4,5-dimethoxybenzene Hydrochloride is the salt form of 1,2-Diamino-4,5-dimethoxybenzene (D416425), which reacts with aldehydes to produce highly fluorescent benzimidazole derivatives. It can be used for the detection of aldehydes as well as DTAN.
References Iwata, T., et al.: Chem. Pharm. Bull., 33, 3499 (1985); Hara, S., et al.: J. Chromatography, 377, 111 (1986); Masui, H., et al: Inorg. Chem., 32, 258 (1993)

Applications 2-Iodobenzonitrile

Applications Trimethyl Bromoorthoacetate is an intermediate in the synthesis of 3,6-Bis(2-hydroxyethyl)-2-pyrazinepropanoic Acid (B444100), an impurity of Clavulanic Acid (C563750).
References Zupke, C., et al.: Biotechnol. Prog., 10, 489 (1994), Finlay, J., et al.: J .Antimicrob. Chemother., 52, 18 (2003),

Applications 4-Chlorostyrene is a reagent primarily used in epoxidation reactions of olefins. Also used in the synthesis of 9-deazaxanthine derivatives as dual A2A antagonists/MAO-B inhibitors.
References Srinivasan, K. et al.: J. Am. Chem. Soc., 108, 2309 (1986); Samsel, E. et al.: J. Am. Chem. Soc., 107, 7606 (1985); Rivara, S. et al.: J. Med. Chem., 56, 1247 (2013);

Applications 2,4-Dichloro-6-nitroaniline

Applications 3-(Difluoromethoxy)benzenesulfonyl Chloride is a useful reagent for the preparation of phenoxypyridylpyrimidine derivatives as inositol requiring enzyme 1 (IRE1) activity modulators.
References Braun, M. G., et al.: PCT Int. Appl. (2020), WO 2020056089 A1

Applications Chlorpropham is particularly useful in agricultural settings. It is used in pesticide products for treatment of plants and soil.
References Wozniak, E., et al.: PCT Int. Appl. (2020), WO 2020118278 A1

Applications 4-(2-Chlorophenyl)-cyclohexanone is used in the synthetic preparation of cyclohexyl pyridylpiperazines as Δ8-Δ7 sterol isomerase ligands with antiproliferative activity.
References Berardi, F., et al.: J. Med. Chem., 51, 7523 (2008)

Applications 4-Benzyloxy-1-bromobenzene (cas# 6793-92-6 ) is a compound useful in organic synthesis.

Applications 1,1-Dichloro-1-(difluoromethoxy)-2,2,2-trifluoroethane is a polyhalogenated methyl ethyl ether with anesthetic properties.
References Sewell, J., Sear, J.: Anesth. Analg., 102, 764 (2006); Trogdon, G., et al.: J. Mol. Model., 13, 313 (2007); Abraham, M., et al.: J. Pharm. Sci., 97, 2373 (2008);

Stability Light Sensitive
Applications Ethyl 2,3-dibromo-3-phenylpropionate

Applications N-[(2,4-Difluorophenyl)methyl]-2,4-difluoro-benzenemethanamine is derived from 2,4-Difluorobenzylamine (D45085), which acts as a reagent for the design of pyrazole derivatives as non-nucleoside heptatitis B virus inhibitors. It is also used as a reagent in the preparation, HIV antiviral activity, SAR, and molecular modelling of hydroxypyridonecarboxylic acids as HIV reverse transcriptase inhibitors.
References Jia, H., et al.: Eur. J. Med. Chem., 123, 202 (2016); Kankanala, J., et al.: J. Med. Chem., 59, 5051 (2016)

Applications 6-Fluoronicotinic acid

Applications 4-(4-Chlorophenyl)-2-butanone has been used as a reactant in the preparation of diarylheptanoids as tumor necrosis factor-α (TNF-α) inhibitors.
References Dhuru, S., et. al.: Bioorg. Med. Chem. Lett., 21, 3784 (2011)

Applications 1-Bromo-2-phenoxyethane (cas# 589-10-6) is a compound useful in organic synthesis.

Applications 6-BROMOHEXANAL (cas# 57978-00-4) is a useful research chemical.

Applications Pentachlorophenyl Cyanoacetate is an intermediate used in the synthesis of Cefacetrile (C231500), which is a cephalosporin antibiotic. Antibacterial.
References Dajan, A., et al.: Vet. Microbiol., 35, 213 (1993), Becker, M., et al.: Anal. Chim. Acta, 520, 19 (2004), El-Shaboury, S., et al.: J. Pharm. Biomed. Anal., 45, 1 (2007),

Applications Methyl 3-chloro-3-oxopropionate is a reagent that is used in the synthesis of pyrrolopiperidinone acetic acids as CRTh2 antagonists/
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Andres, M., et al.: Bioorg. Med. Chem. Lett., 24, 5111 (2014);

Stability Hygroscopic

Applications Dibromoacetic Acid is a halogenated disinfection byproduct. Dibromoacetic Acid was found to induce apoptotic changes and hydroxyl radical formation in human peripheral blood mononuclear cells (PBMCs). Dibromoacetic Acid also found to exhibit carcinogenic activity in which mice and rats were exposed to drinking water containing different concentrations of Dibromoacetic Acid that resulted in increased incidences of mononuclear cell leukemia, malignant mesothelioma, hepatocellular neoplasms, and hepatoblastoma.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Michalowicz, J., et al.: Toxicol. In Vitro 29, 1416 (2015); Natl Toxicol Program Tech Rep Ser. 537, 1 (2007)

Applications O-Cyclopropylmethyl-hydroxylamine, Hydrochloride (cas# 74124-04-2) is a compound useful in organic synthesis.

Applications 3-Acetyl-3-chlorodihydrofuranone (cas# 2986-00-7) is a compound useful in organic synthesis.
References Litvak, M., et al.: Pharm. Chem. J., 39, 500 (2005), Thomas, A., et al.: Bioorg. Med. Chem. Lett., 18, 2206 (2008),

Applications 2-[4-(Bromomethyl)phenyl]propionic Acid is a key intermediate for the synthesis of loxoprofen sodium a nonsteroidal anti-inflammatory drug.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wu, R., et al.: Zhongguo Yiyao Gongye Zazhi, 46, 806 (2015); Zhang, X., et al.: Zhongguo Yaowu Huaxue Zazhi, 20, 25 (2010)

Stability Light Sensitive
Applications 1,2-Dichloroethylene (Mixture of cis and trans) is a chlorinated solvent used in organic synthesis. Environmental pollutant found in river ecosystems contributing to habitat degradation.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Schaefer, R. et al.: Freshwater Biol., 61, 2116 (2016);

Applications 4-(Chloromethyl)-2,4'-difluoro-1,1'-biphenyl, is a building block used in chemical synthesis of more complex compounds.

Applications 2-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)acetonitrile (cas# 68119-31-3) is a useful research chemical.

Applications 4-Cyano-3,5-difluorophenylboronic acid