Halogénures organiques

Applications 2-(2-bromo-4,5-dimethoxyphenyl)ethan-1-amine hydrochloride (cas# 103275-23-6) is a useful research chemical.

Applications 1,1-Dibromoethane is a useful reagent for setereoselective synthesis of (+)-phorboxazole A via Petasis-Ferrier rearrangement. It is also used for preparation of olefinic enol ether.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Smith, A., et al.: J. Am. Chem. Soc., 123, 10942 (2001); Fujimura, O, et al.: J. Org. Chem., 59, 4029 (1994);

Applications Ethyl hydrazinoacetate, HCl

Applications 2-(4-CHLOROPHENYL)PROPANOIC ACID (cas# 938-95-4) is a useful research chemical.

Applications 5-Amino-2-chlorobenzotrifluoride is a compound useful in organic synthesis. It also performs a radioprotective activity against ionizing radiations.
References Blickenstaff, R. T., et al.: J. Pharm. Sci., 83, 219 (1994); Kumari, P., et al.: Org. Biomol. Chem., 16, 2049 (2018)

Applications p-Trifluoromethylphenyl is used in the synthesis of P2Y1 antagonists and antithrombotic agents. Also, used in the synthesis of potent myeloid cell leukemia inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chao, H. et al.: J. Med. Chem., 56, 1704, 2013; Friberg, A. et al.: J. Med. Chem., 56, 15 (2013);

Applications 2-Bromo-4,5-dimethoxybenzoic Acid (cas# 6286-46-0) is a compound useful in organic synthesis.

Stability Light Sensitive
Applications Methyl 2-Iodobenzoate is used as a reagent in the synthesis of Montelukast Sodium Salt (M568000); a selective leukotriene D4-receptor antagonist that is used as an antiasthmatic. Methyl 2-Iodobenzoate is also used as a reagent in the synthesis of isoquinolinone-based tricycles as polyribose polymerase-1 inhibitors.
References Bollikonda, S., et al.: J. Org. Chem., 80, 3891 (2015); Labelle, M., et al.: Bioorg. Med. Chem. Lett., 5, 283 (1995); Jones, T.R., et al.: Can. J. Physiol. Pharmacol., 73, 191 (1995); Markham, A. and Faulds, D.: Drugs, 56, 251 (1998); Chen, J., et al.: Bioorg. Med. Chem. Lett., 24, 2669 (2014)

Applications Cyclopentyl chloride (cas# 930-28-9) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Stability Moisture Sensitive
Applications Tri-n-octylchlorotin is an octyltin compound used to study the growth and fatty acid of the microscopic fungus Cochliobolus lunatus. It is also an organotin reagents used to covalently functionalize oxide nanostructures and multi-walled C nanotubes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Felczak, A., et al.: Process Biochem., 49, 295-300 (2014); Gomathi, A., et al.: J. Mater. Chem., 19, 988-995 (2009);

Applications Bromocyclobutane
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2,3-Dibromopropionamide (cas# 15102-42-8) is a useful research chemical.

Applications 2-Chloro-1,3-benzothiazole is used in the synthesis of CBTs which are good building blocks for bioluminescent compounds for imaging.
References Hauser, J. et al.: Bell. J. Org. Chem., 12, 2019 (2016);

Applications 4-chlorocatechol was a major degradation product of 4-chloro-2-aminophenol (4C2AP)1. The degradation of 4-chlorocatechol was catalyzed by cphA-I enzyme2.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Quintelas, C., et al.: Environ. Sci. Pollut. Res. Int., 20, 1374 (2013); Costa, F., et al.: Biodegradation, 23, 81 (2012)

Applications 1-Cyclopropyl-2-(2-fluorophenyl)-2-hydroxy-ethanone is a useful synthetic intermediate in the synthesis of Prasugrel (P701150, HCl); an antiplatelet agent.
References Wiviott, S.D., et al.: Circulation, 116, 2923 (2007); Xu, X., et al. Faming Zhuanli Shenqing. CN 102718642 A 20121010. Oct 10, 2012; Wang, G., et al. Faming Zhuanli Shenqing. CN 101402556 A 20090408. Apr 8, 2009

Applications An intermediate of racemic Atomoxetine.
References Hage, A., et al.: Biotechnol. Bioeng., 73, 69 (2001), La Regina, G., et al.: J. Med., Chem., 51, 3841 (2008),

Stability Hygroscopic
Applications 3-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]propanimidamide hydrochloride (cas# 76833-47-1) is a useful research chemical.

Applications 3-(4-Bromophenyl)-2-propen-1-ol (cas# 105515-33-1) is a useful reagent for the preparation of aryltetralin cyclic ether lignans.
References Xiang, J. C., et al.: Angew. Chem. Int. Ed., 59, 21195 (2020)

Applications This compound is used in the synthesis of Diclazuril (D436200) and diclazuril derivatives.

Applications 2-Chloroethyl Methyl Ether is used as a reagent in the synthesis of Piperonyl Methoxyethyl Ether (P490475); a selective inhibitor of the cytochrome P450-dependent monooxygenase from the housefly.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Motoyama, N., et al.: Rev. Pestic. Toxicol., 1, 173 (1991)

Applications 1,5-Dibromo-1-(2-fluorophenyl)-2-pentanone is used as a reagent in the synthesis of Prasugrel (P701150) and its intermediates.
References Nyulasi, B., et al. PCT Int. Appl. WO 2012052788 A1 20120426. Apr 26, 2012

Applications 9-Hydroxyfluorene is a wake promoting agent and is considered as the next generation anti-narcolepsy drug. It is also a potential environmental carcinogen.
References Dunn, D., et al.: Bioorg. Med. Chem. Lett., 22, 3751 (2012); Clark, J., et al.: Environ. Res., 117, 132 (2012); Li, F., et al.: Environ. Toxicol. Phar., 32, 373 (2011)

Impurity Diclofenac Impurity
Applications 2,6-Dichloroaniline (cas# 608-31-1) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 3-Chlorobenzene-1,2-diamine

Applications 2-Cyclopentyl-4-chlorophenol, Technical Grade (cas# 13347-42-7) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Stability Light Sensitive
Applications 3-Chlorocyclohexene (cas# 2441-97-6) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Tetrabromophthalic Anhydride is a brominated flame retardant used as additives in plastics to decrease the rate of combustion of these materials, leading to greater consumer safety.
References El-Fouly, M., et al.: Environ. Toxicol. Chem., 13, 1581 (1994), Fowles, J., et al.: Toxicology , 86, 49 (1994),

Applications Ethylamine Hydrochloride a chemical used in various chemical organic syntheses and biological studies.
References Miller, M.M. et al.: Bioorg. Med. Chem. Lett., 22, 6503 (2012); Yasui, K. et al.: Prot. Sci., 19, 486 (2010);

Applications Fluoroiodomethane is an synthetic precursor for the fluoromethylation of radiopharmaceuticals.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chin. F., et al.: J. Label. Compd. Radiopharm. 49, 1 (2005); Tedder, J., et al.: J. Chem Soc., 1846 (1975); Zheng, L., et al.: App. Rad. Isotopes., 52, 55 (2000);

Applications It is used in a new method for conjugation of carbohydrates to proteins using an aminooxy-thiol heterobifunctional linker.
References Tietze, L., et al.: Bioconjugate Chem., 2, 148 (1991), Peeters, C., et al.: Infect. Immun., 60, 1826 (1992), Brask, J., et al.: J. Pept. Sci., 6, 290 (2000),

Applications 7-Bromoheptanol is a useful synthetic intermediate. It can be used to prepare N-substituted [(carboxymethyl)phenoxy]ethyl benzoxazinones as PPARγ agonists and antidiabetic (type 2) agents. It can also be used to prepare thiochroman and chroman derivatives as pure antiestrogens.
References Rybczynski, P., et al.: J. Med. Chem., 47, 196 (2004); Kanbe, Y., et al.: Bioorg. Med. Chem., 14, 4803 (2006)

Applications 2-​Amino-​3-​chloro-​5-​trifluoromethylpyrid​ine acts as a reactant in the synthesis of novel imidazo[1,2-a]pyridine-coumarin hybrid molecules as inhibitors of NS5B in potential treatment of Hepititis C.
References vManvar, P. et al.: Tetrahedron 72, 1293 (2016);

Applications 1-(4-Amino-3,5-dichlorophenyl)-2-ethanone (cas# 37148-48-4) is a compound useful in organic synthesis.

Applications 1,5-Dichloropentane is used in bacterial and spontaneous dehalogenation of organic compounds.
References Omori, T., et al.: Appl. Environ. Microbiol., 35, 512 (1978)

Stability Hygroscopic
Applications 4,4'-Oxybis[p-(phenylsulfonylaniline)] Hydrochloride is used in the preparation of polyamido polysulfone thermoplastics.
References Cho, I., et al.: U.S. (1975), US 3859252 A 19750107

Applications Phenyl chloroformate is a corrosive liquid that is used to synthesize Urazole, a five membered heterocyclic compound that reacts with aldoses to form α and β pyranosides and furanosides. Phenyl chloroformate is also used as a reagent to prepare Sorafenib (S676850), a multikinase inhibitor that targets the tumour and tumour vasculature in patients with melanoma.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Boettecher, B. & Meister, A.: Anal. Biochem., 138, 449 (1984); Chai, W., et al.: Tetrahedron Lett., 53, 3514 (20112); Eisen, T., et al.: Brit. J. Cancer, 95, 581 (2006); Kolb, V., et al.: J. Mol. Evol., 38, 549 (1994); Llovet, J., et al.: Engl. J. Med., 359, 378 (2008)

Applications tert-Butylhydrazine Hydrochloride is a a hydrazine compound used in organic synthesis for aromatic nucleophilic N-N exchange reaction. tert-Butylhydrazine Hydrochloride is also used in the preparation of insect growth regulator.
References Hojo, M. et al.: Synthesis, 6, 481 (1990); Zhang, J. et al.: Huax. Shijie, 36, 576 (1995);

Applications 2-Chloro-p-xylene is a toxic compound found in algae.
References Tsai, K.; et al.: Environ. Toxicol. Chem., 26, 1931 (2007).

Applications 10-Bromo-1-aminodecane, Hydrobromide (cas# 24566-82-3) is a compound useful in organic synthesis.

Applications 1-Bromo-1,1-dichloro-2-propanone is a disinfection byproduct in drinking water.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Krasner, S., et al.: Environ. Sci. Technol., 40, 7175 (2006); Richardson, S., et al.: Water Air Soil Poll., 123, 95 (2000)

Stability Hygroscopic
Applications 1H,1H,2H,2H-Perfluorohexanol is used in the synthesis of polymer coatings with controlled surface topography. As well used in the preparation of star polymers as fluorous nanocapsules for the encapsulation and release of perfluorinated compounds.
References Szczepanski, C. et al.: ACS Mat. Int., 9, 3063 (2016);

Stability Hygroscopic
Applications Dihydrogen Hexachloroplatinate Hexahydrate is a reactant used in the synthesis of platinum, carbon dot hybrid nanoparticles.
References Shin, H. et al.: ACS. Catal., 6, 3914 (2016);

Applications Used for preparation of an inhibitor of the NLS-derived BC peptides.
References Byk, G., et al.: J. Med. Chem., 39, 3174 (1996), Gallay, P., et al.: J. Virol., 70, 1027 (1996), Nigg, E., et al.: Nature, 386, 779 (1997), Friedler, A., et al.: Biochemistry, 37, 5616 (1998),

Stability Light Sensitive
Applications 4-Bromo-1-butene is a brominated alkene used as a reagent in organic synthesis.

Applications 2,4,5,6-Tetrachloro-m-xylene, is an intermediate for the synthesis of pesticides and metabolites. It can also be used for the preparation of Quinol nitrates.
References Suzuki, H., et al.: J. Chem. Soci. Comm., 51 (1957); Snyder, J. L., et al.: Anal. Chem., 64, 1940 (1992);

Applications 3,4,5-Trichlorocatechol has found to be toxic to marine algal.
References Ertuerk, M.D., et. al.: J. Mol. Graph. Model., 38, 90 (2012)