Halogénures organiques

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1,1'-(2,2,2-Trichloroethylidene)Bis(4-fluorobenzene) is a fluorine-containing compound that is used in analytical chemistry. It is a synthetic nucleophile that reacts with electron deficient molecules to form covalent bonds. This substance has been shown to denature proteins and inhibit the activity of enzymes such as DNA polymerase, RNA polymerase, and phosphodiesterases. 1,1'-(2,2,2-Trichloroethylidene)Bis(4-fluorobenzene) also inhibits the signal transduction pathway in Drosophila melanogaster (fruit fly). The effects of this substance on blood flow velocity were studied in an animal model system.

Intermediate in the synthesis of idelalisib (CAL 101)

4-Fluorophenoxyacetic acid is a chemical compound that is used as an insecticide. It has been shown to be effective against the planthopper and ipomoea, two agricultural pests. 4-Fluorophenoxyacetic acid binds to the active site of a specific protein in the insect's cells, inhibiting its function and causing cell death. 4-Fluorophenoxyacetic acid also inhibits the growth of human breast cancer cells in culture. The molecular weight of this compound is 180.2 g/mol and has a melting point of 185°C with a boiling point of 232°C at atmospheric pressure. 4-Fluorophenoxyacetic acid can be synthesized by reacting phenol with acetic anhydride in the presence of palladium complexes and nitrogen atoms. The reaction mechanism for this synthesis is nucleophilic addition to form a covalent bond between the nitrogen atom and sulfur atom on one side of the

Rhodium(III) chloride hydrate is a catalyst that is used in the oxidation of aromatic hydrocarbons. It has been shown to have an acidic reaction with hydrochloric acid and is used in the oxidation of benzene, toluene, ethylbenzene, and xylene. Rhodium(III) chloride hydrate has also been shown to be a good catalyst for the production of polycyclic aromatic hydrocarbons from light emitting diodes. This product can be used as an oxidizing agent in organic synthesis reactions. The 6-Fluoro-3-indoxyl-beta-D-galactopyranoside is an antituberculosis drug that belongs to the class of rifamycins. It is the most active of the rifamycins for the treatment of tuberculosis. Rifapentine inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of

3,3'-Dichlorobenzidine dihydrochloride is a chemical compound that is used in the manufacture of industrial chemicals. 3,3'-Dichlorobenzidine dihydrochloride is also used as a biochemical to detect copper and chloride ions in urine samples. This chemical has shown binding activities with receptor α, which is responsible for the transmission of nerve impulses. 3,3'-Dichlorobenzidine dihydrochloride has been shown to have a high affinity for receptor α and can be used as an antagonist for this receptor in binding studies.

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2-Bromo-5-benzoylthiophene is a brominated hydrophobic compound. It has a catalytic activity and can be used as an antibacterial agent. The 9-oxime of 2-bromo-5-benzoylthiophene is more active than the free drug and is capable of inhibiting the growth of bacteria in vitro. This oxime also has a higher affinity for DNA gyrase and topoisomerase IV than other drugs in this class, which may be due to its hydrophobic nature or bromine substitution. Molecular modeling studies have shown that the chlorine atom in the 9-oxime plays an important role in stabilizing the complex formed with DNA gyrase or topoisomerase IV, which could explain its high activity against these enzymes.

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6-Bromohexanoic acid methyl ester is a linker that can be used in the synthesis of amides. This compound is synthesized by reaction between 2-bromobutyric acid and malonic acid, followed by hydrolysis with sodium hydroxide. 6-Bromohexanoic acid methyl ester is an efficient method for the preparation of amides. It is biologically active and has been shown to have anti-inflammatory properties in biological studies.

1-Chloroethyl isopropyl carbonate (CEPC) is a cefpodoxime proxetil metabolite that is formed from the chlorination of 1-chloroacetamide in the presence of isopropyl. CEPC has been shown to have a high yield and can be synthesized from readily available, inexpensive starting materials. It is metabolized by human liver microsomes and plasma, yielding 7-aminocephalosporanic acid, cefpodoxime, and thiourea. This compound can also be used as an intermediate for the synthesis of other compounds such as cefotaxime and thiourea.

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3-Chloro-4-fluorobenzoyl chloride is a chlorinating agent that is used as a fungicide, phytotoxin, and an insecticide. It is an effective pesticide against many fungal diseases that affect plants. 3-Chloro-4-fluorobenzoyl chloride has been shown to be effective in the treatment of cervical cancer and other cancers. It also has photochromic properties, which make it useful for detecting skin cancer. 3-Chloro-4-fluorobenzoyl chloride is synthesized by reacting chlorine with 4-fluorobenzoyl chloride in the presence of a base such as sodium hydroxide or potassium hydroxide. This reaction can be carried out in either liquid or gaseous phases. The product can be purified by vacuum distillation or crystallization. 3-Chloro-4-fluorobenzoyl chloride is primarily used as a fungicide