Halogénures organiques

<p>Applications 1,1'-Oxybis[2,3,4-tribromo-benzene] is a polybrominated diphenyl ether (PBDE) used as a flame retardant.<br>References Rayne, S., et al.: Environ. Int., 32, 575 (2006); Jakobsson, K., et al.: Chemosphere, 46, 709 (2002)<br></p>

<p>Applications Bis-(1,2,2,2-tetrafluoroethyl) Ether is an impurity in the preparation of Desflurane (D290085), a general anesthetic.<br>References Visoiu, M. et al.: Anest. Anal., 118, 388 (2014); Duma, A. et al.: Reg. Anest. Pain Med., 39, 31 (2014);<br></p>

<p>Stability Moisture Sensitive<br>Applications 2,4-Difluoro-3-formylphenylboronic acid<br></p>

<p>Applications 2-Bromo-2-(2-chlorophenyl)acetic Acid is used as an intermediate in the preparation of biologically active compounds such as the antithrombotic Clopidogrel (C587250).<br>References Chen, J. et al.: Hech. Huax., 18, 586 (2010);<br></p>

<p>Applications 2-Nitrobenzenediazonium Tetrafluoroborate (cas# 365-33-3) is a compound useful in organic synthesis.<br></p>

<p>Applications Trimethyl Bromoorthoacetate is an intermediate in the synthesis of 3,6-Bis(2-hydroxyethyl)-2-pyrazinepropanoic Acid (B444100), an impurity of Clavulanic Acid (C563750).<br>References Zupke, C., et al.: Biotechnol. Prog., 10, 489 (1994), Finlay, J., et al.: J .Antimicrob. Chemother., 52, 18 (2003),<br></p>

<p>Applications Methyl 5-cyano-2-fluorobenzoate<br></p>

<p>Applications 1-(4-(2-Bromoethyl)phenyl)ethanone (cas# 40422-73-9) is a useful research chemical.<br></p>

<p>Applications 7-Chloro-4-oxo-4H-chromene-2-carboxylic acid (cas# 114741-22-9) is a useful research chemical.<br></p>

<p>Stability Moisture Sensitive<br>Applications Di-tert-butyl chloromethyl phosphate (cas# 229625-50-7) is a useful research chemical.<br></p>

<p>Stability Air Sensitive<br>Applications 4-IODO-2-NITROANILINE (cas# 20691-72-9) is a useful research chemical.<br></p>

<p>Impurity Budesonide EP Impurity J<br>Applications 9α-Bromobudesonide (Budesonide EP Impurity J) is an impurity of Budesonide (B689460), a non-halogenated glucocorticoid intended for the local treatment of lung disease.<br>References Ryrfeldt, Å., et al.: Eur. J. Respir. Dis., 122, 86 (1981); Vestbo, J., et al.: Lancet, 353, 1819 (1999)<br></p>

<p>Applications Methyl 5-bromofuran-2-carboxylate<br></p>

<p>Applications 2-(3-Amino-4-chlorobenzoyl)benzoic Acid is a useful synthetic intermediate. It is used to prepare protein kinase C phosphorylates synthetic fluorescent reporter.<br>References Chen, C., et al.: J. Am. Chem. Soc., 124, 3840 (2002)<br></p>

<p>Applications Trifluoromethanesulfonic Acid Magnesium Salt is a strong acid that is used as a catalyst for esterification.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Howells, R. D., et al.: Chemical Rev., 77, 69 (1977);<br></p>

<p>Applications Dibromoacetic Acid is a halogenated disinfection byproduct. Dibromoacetic Acid was found to induce apoptotic changes and hydroxyl radical formation in human peripheral blood mononuclear cells (PBMCs). Dibromoacetic Acid also found to exhibit carcinogenic activity in which mice and rats were exposed to drinking water containing different concentrations of Dibromoacetic Acid that resulted in increased incidences of mononuclear cell leukemia, malignant mesothelioma, hepatocellular neoplasms, and hepatoblastoma.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Michalowicz, J., et al.: Toxicol. In Vitro 29, 1416 (2015); Natl Toxicol Program Tech Rep Ser. 537, 1 (2007)<br></p>

<p>Stability Hygroscopic<br></p>