Composés organiques chiraux

Applications Intermediate in the preparation of serum biotinidase resistant Biotin derivatives used to make pretargeted …

Applications Inhibitor for treatment of Alzheimer's disease. References Alper, P. B., et al.: Bioorg. Med. …

Applications Cis-(-)-4-Amino-3-(3,4-dimethoxyphenyl)-1-methylpiperidine is an intermediate in the synthesis of Tolafentrine (T531000), which is a dual-selective …

Applications Intermediate in the preparation of Aliskiren. References Zhi, C., et al.: J. Med. Chem., …

Applications (2R,3R,4E,11Z)-Ethyl 2-amino-3-hydroxyoctadeca-4,11-dienoate is an intermediate of (4E,14Z)-Sphingadienine-C18 (S680630), a sphingoid base of sea cucumber …

Applications N-[(6S)-8-Fluoro-5,6-dihydro-4-(1-methylethyl)-6-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]benzo[h]quinazolin-2-yl]-N-methylmethanesulfonamide is an impurity of the HMG-CoA reductase inhibitor Rosuvastatin (R700500).

Applications 1-(sec-Butyl)-4-(4-(4-(4-(((2S,4S)-2-(chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one is an intermediate in the synthesis of Itraconazole (I937500), an orally active antimycotic …

Applications An Amphotericin B derivative as medical fungicide. References Fujii, G., et al.: Biochemistry, 36, …

Applications Rapamycin 31,42-Bis(2,2,5-trimethyl-1,3-dioxane-5-carboxylate) is an impurity of Rapamycin (R124000), a triene macrolide antibiotic isolated from …

Applications Deserpidine, is an antihypertensive drug related to Reserpine (R144600). It is naturally found in …

Applications Fmoc-tyr(2-cltrt)-oh

Applications Intermediate in the preparation of 4α,25-Dihydroxy Vitamin D3 (D455010).

Applications (3S,4S,5R)-5-(Acetyloxy)-3,4-dihydroxy-1-cyclohexene-1-carboxylic Acid Ethyl Ester is an intermediate in the synthesis of Shikimate-3-phosphate (S357026), an …

Applications A byproduct formed during the synthesis of 1-Acetyl-2-deoxy-3,5-di-O-benzoylribofuranose

Applications D-Valine methyl ester hydrochloride is a protected form of D-Valine (V094200). D-Valine (an isomer …

Applications Vitamin D3 (V676045) analog. References Roy, A., et al.: Steroids, 60, 530 (1995);

Applications Reagent used for asymmetric syntheses. References Schlessinger, R., et al.: J. Org. Chem., 28, …

Applications O-Ethyl-D-norvaline is used as an intermediate in the synthesis of Perindopril (P287500), an angiotensin-converting …

Applications (R)-1-(3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl)-N,N-dimethylmethanamine is an intermediate in the synthesis of ent-Ivabradine Hydrochloride (I940505), which is the …

Applications (3R,4R)-tert-Butyl 4-Methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carboxylate is an intermediate in the synthesis of 5,6-Dihydro CP-690550 (D450240), an impurity …

Applications (+)-cis-Khellactone is an intermediate in the synthesis of rac Samidin (S110500), a potent vasodilatory …

Applications (S)-2-(2,6-Dimethylphenyl)-3,3-dimethylhexahydroimidazo[1,5-a]pyridin-1(5H)-one is an impurity of R674990), a metabolite of (S)-Ropivacaine (R674995), that acts as …

Applications 9-((1S,3R,4S)-4-Hydroxy-3-(((4-methoxyphenyl)diphenylmethoxy)methyl)-2-methylenecyclopentyl)-2-(((4-methoxyphenyl)diphenylmethyl)amino)-1H-purin-6(9H)-one is a Monomethoxytrityl protected intermediate of 4’-epi-Entecavir (E558930), an epimeric impurity of the …

Applications (4S,5S)-Methyl 2,2,5-Trimethyl-4-(prop-1-en-2-yl)-1,3-dioxolane-4-carboxylate is an impurity in the synthesis of (+)-Echimidine N-Oxide, which is a …

Applications A tetrazole-containing Rapamycin analog as immunomodulator and useful in the treatment of restenosis and …

Applications 7-Benzoyloxy-hesperetin 3’-O-(2’,3’,4’-Tri-O-acetyl)-β-D-glucuronide Methyl Ester is an intermediate in the synthesis of Hesperetin 3’-O-β-D-Glucuronide (H289505) …

Applications Apicidin is a potent (nM) cell permeable inhibitor of histone deacetylase. Also, Apicidin exhibits …

Applications (3S)-1-Tosyl-α,α-diphenyl-3-pyrrolidineacetonitrile is a reactant used in the preparation of Darifenacin Hydrobromide (D193400), which is …

Applications An intermediate in the preparation of serotonin 5-HT2a receptor antagonists References Ullrich, T., et …

Applications Intermediate for the preparation of Simvastatin analogs as HMG-CoA reductase inhibitors.

Applications A metabolite of Vinorelbine (V315000). References Elmarakby, S., et al.: J. Med. Chem., 32, …

Applications 6-Bromo Norgestrel is an intermediate in the synthesis of Norgestrel (N689500) impurities.

Applications 6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine is an impurity of Pitavastatin (P531000), a competitive inhibitor of HMG-CoA reductase. Antilipemic. …

Applications [2R-[2α,6α,7β(R*)]]-7-[[[[(1,1-Dimethylethoxy)carbonyl]amino]phenylacetyl]amino]-3-methylene-8-oxo-5-thia-1-azabicyclo[4.2.0]octane-2-carboxylic Acid 5-Oxide is an intermediate in the synthesis of Cephalosporin derivative with bactericidal …

Applications rac-Nornicotine is a metabolite of rac-Nicotine (N412420). References Hecht, S., et al.: Carcinogenesis, 9, …

Applications Intermediate in the preparation of Lubiprostone.

Applications Carfilzomib 2-Acetate is an intermediate in the synthesis of Carfilzomib (2R,4R)-Diol (C183525), which is …

Applications Derivative of Artemisinin. Antimalarial. References Li, Y., et al.: Acta Pharm. Sin., 16, 429 …

Applications 7-O-(Triethylsilyl)-2’-O-tert-butyl(dimethyl)silyl-2-debenzoyl-[2,4]oxol Pacliaxel is an intermediate in the synthesis of Paclitaxel (P132500) related compound.

Applications N-Formyl 10-Oxo 7-Epi-docetaxel is an epimer of N-Formyl 10-Oxo Docetaxel (F700765), which is an …

Applications Cholesterol (C432501) derivative. An intermediate in the preparation of 4α,25-Dihydroxy Vitamin D3 (D455010).

Applications 4R,6R)-6-[2-[(2S)-1,2-Dihydro-6-hydroxy-2-methyl-1-naphthalenyl]ethyl]tetrahydro-4-hydroxy-2H-pyran-2-one is an impurity of Pravastatin Sodium (P702000), which is a competitive inhibitor of …

Applications H-LEU-MET-OH (cas# 36077-39-1) is a useful research chemical.

Applications 7-O-(Triethylsilyl-2-debenzoyl-4-desacetyl-hexahydrobaccatin III is an intermediate in the synthesis of Paclitaxel (P132500) related compound.

Applications Intermediate in the preparation of prostaglandin derivatives

Applications An analog of glutaryl-7-amino cephalosporanic acid (GL-7-ACA). Can inhibit and specifically alkylate GL-7-ACA acylase …

Applications Protected Glutamine. References Ohshiro, T., et al.: App. Microbiol. Biotechnol., 48, 546 (1997), Fox, …

Applications Cis-7-Hydroxy Didesmethyl Sibutramine Hemifumarate Salt is a metabolite of Sibutramine (S422500), a serotonin and …

Applications (4R,6R)-4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-2,2,6-trimethyl-cyclohexanone is an intermediate used in the synthesis of Xanthoxin (X742500), which is a …

Applications 5β-Pregnane-3α,11,17α,20α-tetrol is an urine steroid used as a biomarker for detecting malignancy in adrenal …

Applications (S)-(+)-3-Aminopiperidine Dihydrochloride (cas# 334618-07-4) is a compound useful in organic synthesis. References Ishikawa, M., …

Applications Duloxetine Maleate is a dual serotonin and norepinephrine reuptake inhibitor (SNRI) and is used …

Applications Fluifort is used in anti-cancer treatment as a selective scavenger of reactive oxygen intermediates. …

Applications (4R)-3-(1-Oxo-4-penten-1-yl)-4-(phenylmethyl)-2-oxazolidinone (cas# 155399-10-3) is a compound useful in organic synthesis.

Applications Methyl 15-Oxo Gibberellin A3 Diacetate is a derivative of Gibberillic Acid (G377450), a hormone …

Applications 19-Hydroxy-10-deacetylbaccatin III is an impurity of Baccatin III (B101000) and is extracted from the …

Applications 1-(sec-Butyl)-4-(4-(4-(4-(((2R,4R)-2-(chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1H-1,2,4-triazol-5(4H)-one is an intermediate in the synthesis of Itraconazole (I937500), an orally active antimycotic …

Applications Methyl 3,13-Diacetylgibberellate is a derivative of Gibberillic Acid (G377450), a hormone that is found …

Applications 5-(2-Ethoxy-2-oxoethyl)-4-oxo-3,4-dihydropyridine-1(2H)-carboxylic Acid tert-Butyl Ester is used in the synthesis of Clopidogrel (C587250), an antithrombotic …

Applications Used in the preparation of ester-linked docetaxel-monosaccharide conjugates. References Shimoda, K. & Kubota, N.: …

Stability Hygroscopic Applications The main degradation product of Reserpine (R144600). References Krebs, K.G. , et …