Recherche sur le cancer

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM, IF&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM, IF&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM, IF&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM, IF&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM, IF&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>Antibody Type: Rabbit Monoclonal&lt;br&gt;<br>Application: ELISA, FCM&lt;br&gt;<br>Reactivity: Human</p>

<p>DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.</p>

<p>IR 783 is a heptamethine cyanine fluorescent probe for in vivo imaging of tumor cells. It displays excitation/emission maxima of 633/780 nm, respectively.</p>

<p>MKT-077 (FJ-776) is a cationic rhodacyanine dye that demonstrates antiproliferative activity against cancer cell lines.</p>

<p>Dark green, bronze-lustered Methylene Blue trihydrate is a deep blue dye in water/alcohol, used in staining, cyanide treatment, and methemoglobin reduction.</p>

<p>Applications Bisabolene is a sesquiterpene and can be extracted from oregano and other aromatic plants. It may be a potential anticancer agent that can induce apoptosis in A549 cancer cell line.<br>References Grosso, N. R., et al.: Argent., Pat. Appl. AR 90961 A1 20141217 (2014); Yfanti, P., et al.: Am J Plant Sci. 6, 2092 (2015)<br></p>

<p>Applications Chelidonine Hydrochloride is an alkaloid agent capable of ameliorating oxidative stress and hepatic injury in mammals. In addition, a main component of the anticancer alkaloids present in Glaucium flavum.<br>References Bournine, L. et al.: Int. J. Mol. Sci., 14, 23533 (2013); Paul, A. et al.: Env. Toxicol. Pharm., 36, 937 (2013);<br></p>

<p>Applications Apricoxib, is an orally active, selective COX-2 inhibitor, used as as an analgesic and anti-inflammatory agent, and also has anticancer potential, since COX-2 inhibition can reduce tumor growth and augment therapy.<br>References Kirane, A, et al.: Clinical Cancer Res., 18, 5031 (2012); Rohatagi, Sh., et al.: British J. Clin. Pharmaco., 66, 60 (2008);<br></p>

<p>Applications Lanosterol is a sterol cholesterol precursor that maintains a stable concentration in the cortex of rats during aging however concentrations of Lanosterol increases in the liver during aging. Lanosterol is found in Mushroom Inonotus obliquus (I.obliquus) which is known to have anti-inflammatory and anticancer properties.<br>References Smiljanic, K., et. al.: Lipids, 48, 1069 (2013); Ma, L., et. al.: Food Chem., 139, 503 (2013)<br></p>

<p>Applications Triterpenoid which can inhibit the proliferation of leukemia HL-60 cells.<br>References Cho, J., et al.: Pulmon. Pharmacol. Ther., 23, 190 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Saha, S., et al.: J. Agric. Food Chem., 58, 434 (2010),<br></p>

<p>Applications Benz[a]anthracen-3-ol is a derivative of the most potent carcinogenic hydrocarbon, 7,12-Dimethylbenz[a]anthracene (D464500), a highly potent carcinogen that is activated by microsomal enzymes to a diol epoxide metabolite that binds covalently to DNA in mammalian cells, leading ultimately to tumor induction. Benz[a]anthracen-3-ol is used in carcinogenesis studies relating to breast cancer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harvey, R. et al.: J. Org. Chem., 69, 2024 (2004); Harvey, R. et a;.: J. Med. Chem., 31, 154 (1988); Lee. H. et al.: J. Org. Chem., 51, 3501 (1986); Huggins, C., et al.: Proc. Nat. Acad. Sci. U.S.A., 58, 2253 (1967), Dipple, A., et al.: N. Cancer Res., 43, 4123 (1983);<br></p>

<p>Applications A metabolite of Temozolomide, an antineoplastic.<br></p>

<p>Applications A novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer. A microtubule inhibitor.<br>References Agarwal, N. et al.: Fut. Oncol., 7, 15 (2011); Mita, A. et al.: Clin. Cancer Res., 15, 723 (2009); Figg, W.D. et al.: Cancer Biol. Ther., 10, 1233 (2010);<br></p>

<p>Applications Methyltriphenylphosphonium Bromide is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.<br>References Selassie, C.D. et al.: J. Med. Chem., 33, 1914 (1990); Venkatachalam, M.A et al.: Kidney Int., 49, 449 (1996);<br></p>

<p>Applications An oleic acid synthetic analog that is an effective non-toxic anticancer drug with a wide spectrum against different types of cancer. An antihypertensive.<br>References Llado, V. et al.: J. Cell. Molec. Med., 14, 659 (2010); Alemany, R. et al.: J. Lip. Res., 47, 1762 (2006); Martinez, J. et al.: J. Pharmacol. Exp. Therap., 315, 466 (2005);<br></p>

<p>Stability Hygroscopic, Temperature Sensitive<br>Applications Gemcitabine Triphosphate is a phosphorylated metabolite of Gemcitabine (G305000), an antineoplastic agent.<br>References Kennedy., E.P., et al.: J. Biol. Chem., 222, 193 (1956),<br></p>

<p>Stability Hygrscopic<br>Applications N1,N12-Diacetylspermine Dihydrochloride is a diacetylated derivative of Spermine (S680510) and is recognized as a novel tumor marker in patients with breast and colorectal cancers.<br>References Kato, M., et al.: Anticancer Res., 34, 3053 (2014); Umemori, Y., et al.: Clin. Chim. Acta, 411, 1894 (2010); Kawakita, M., et al.: J. Biochem., 139, 315 (2006); Hiramatsu, K., et al.: Clin. Cancer Res., 11, 2986 (2005)<br></p>

<p>Impurity Irinotecan USP Related Compound E<br>Applications An anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors. Irinotecan USP Related Compound E.<br>References Brangi, M., et al.: Cancer Res., 59 5938 (1999), Miyake, K., et al.: Cancer Res., 59, 8 (1999) , Bom, D., et al.: J. Med. Chem., 43, 3970 (2000) , Gamcsik, M., et al.: Mol. Cancer Ther., 1, 11 (2001).<br></p>

<p>Stability Light Sensitive<br>Applications β-Cembrenediol is an inhibitor of tumor promotion. Novel c-Met inhibitors which are used in anticancer treatments.<br>References Le-Huu, P. et al.: ChemCatChem., 8, 3755 (2016); Ebrahim, H. et al.: Bioorg. Med. Chem., 24, 5748 (2016);<br></p>

<p>Applications Principal pigment of bile and constituent of many biliary calculi.<br>References Stenhagen, R., et al.: Biochem. J., 33, 1591 (1939), Gray, et al.: J. Chem. Soc., 2264, 2268 (1961),<br></p>

<p>Stability Light Sensitive<br>Applications N-Desmethyl (E)-α-Hydroxy Tamoxifen is a N-demethylated, α-Hydroxyated metabolite of Tamoxifen (T006000).<br>References Poon, G.K. et al.: Drug Metab.Dispos. 23,377 (1995); Teunissen, S.F. et al.: J. Pharmac. Biomed. Anal., 55, 518 (2011); Muerdter, T.E. et al.: Clin. Pharmacol. Therap., 89, 708 (2011);<br></p>

<p>Applications Withanolide A, is a neuritogenic steroid. It may act as deterrent for feeding insect larva and other herbivores. Withaferin A, causes activation of Notch2 and Notch4 in human breast cancer cells, and thus used as novel anticancer agents.<br>References Liffert, R., et al.: Chemical Science, 4, 2851 (2013); Lee. J., et al.: Breast Cancer, Res. treat., 136, 45 (2012);<br></p>