Nitrosamines
2629 produits trouvés pour "Nitrosamines"
N Nitroso Tetracaine
Produit contrôléFormule :C15H23N3O3Couleur et forme :NeatMasse moléculaire :293.37N-Nitrosodimethylamine-d6
CAS :Produit contrôléStability Very Volatile
Applications Isotope labelled N-Nitrosodimethylamine is a highly toxic semi-volatile organic compound and a suspected human carcinogen. It induces liver tumors in rats after chronic exposure to low doses (1,2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.
Dangerous Goods Info This compound is forbidden to ship by air under IATA regulations.
References 1. Peto, R. et al.: Cancer Res.1991 Dec 1;51(23 Pt 2):6415-51.2. Lee, ES. et al.: J. Pharm. Pharmacol., 2003 Aug;55(8):1169-74Formule :C2D6N2OCouleur et forme :Colourless to Yellow OilMasse moléculaire :80.12N-(3-(4-Chlorophenyl)-3-(pyridin-2-yl)propyl)-N-methylnitrous Amide
Produit contrôléFormule :C15H16ClN3OCouleur et forme :NeatMasse moléculaire :289.765-(4-Nitrosopiperazin-1-yl)benzofuran-2-carboxylic Acid Ethyl Ester-d4
Produit contrôléApplications Isotope labelled 5-(4-Nitrosopiperazin-1-yl)benzofuran-2-carboxylic Acid Ethyl Ester is an intermediate in the synthesis of Vilazodone (V265000), a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression.
References Hu, B., et al.: Org. Proc. Res. Develop., 16, 1552 (2012); Heinrich, T., et al.: J. Med. Chem., 47, 4684 (2004);Formule :C15D4H13N3O4Couleur et forme :YellowMasse moléculaire :307.338(R)-8-Chloro-1-methyl-3-nitroso-2,3,4,5-tetrahydro-1H-benzo[d]azepine-D4
Produit contrôléApplications (R)-8-Chloro-1-methyl-3-nitroso-2,3,4,5-tetrahydro-1H-benzo[d]azepine-D4 is an intermediate in the synthesis of Lorcaserin hydrochloride (L469897), which is a highly selective 5-HT2C receptor agonist developed for the treatment of obesity.
References Wang, Y., et al.: Drugs. Future., 32, 766 (2007);Formule :C11D4H9ClN2OCouleur et forme :Light BrownMasse moléculaire :228.711
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