Toxicologie

Applications 5,6-Dihydroyangonin is a derivative of Yangonin (Y100550), a lactone isolated from the Kava plant (Piper methysticum). 5,6-Dihydroyangonin was shown to exhibit potential antibacterial and antifungal activities.
References Keledjian, J., et al.: J. Pharm. Sci., 77, 1003 (1988), Clouatre, D., et al.: Toxicol. Lett., 150, 85 (2004), Mathews, J., et al.: Drug Metab. Dispos., 33, 1555 (2005), Clayton, N., et al.: Exp. Toxicol. Pathol., 58, 223 (2007),

Impurity Sofosbuvir Metabolite GS331007
Applications RO 2433 is the deaminated metabolite of β-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine, an effective inhibitor of hepatitis C virus (HCV) replication in vitro.
References Asif, G., et. al.: Antimicrob. Agents Ch., 51, 2877 (2007)

Applications 4-(4-(4-(4H-1,2,4-Triazol-4-yl)phenyl)piperazin-1-yl)phenyl Acetate is an intermediate in the synthesis of Deoxo Anhydro Itraconazole Bromide (D231675). Deoxo Anhydro Itraconazole Bromide is an impurity of Itraconazole (I937500), which is orally active antimycotic drug structurally related to Ketoconazole (K186000). Antifungal.
References Espinel-Ingroff, A., et al.: Antimicrob. Agents Chemother., 26, 5 (1984); Heykants, J., et al.: Mycoses, 32, Suppl 1, 67 (1989); Sugar, A.M.,et al.: Curr. Clin. Top. Infect. Dis., 13, 74 (1993)

Applications The S,S-stereoisomer of Chloramphenicol (C325030). Broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial.
References Bartz, et al.: J. Biol. Chem., et al.: 172, 445 (1948), Gottlieb, et al.: J. Bacteriol., 55, 409 (1948), Szulczewski, D., et al.: Anal. Profiles Drug Subs., 4, 47 (1975), Price, A., et al.: J. Antibiot., 43, 118 (1981), Shalit, I., et al.: Drugs, 28, 281 (1984),

Applications Prednienic Acid is a glucocorticoid steroid. It is used to synthesize various anti-inflammatory compounds such as macrolactonolides by conjugating Prednienic Acid with macrolides.
References Tomaskovic, L., et al.: Bioorg. Med. Chem., 21, 321 (2013);

Applications An impurity of Isoniazid (I821450), which is an antibiotic for treatment of Mycobacterium tuberculosis and inhibits mycolic acid biosynthesis. Intermediate used for the synthesis of analogs of antitumor agent 1-acetyl-2-picolinoylhydrazine.
References Brewer, G.A., et al.: Anal. Profiles. Drug. Subs., 6, 183 (1977), Weber, W.W., et al.: Clin. Pharmacokinet., 4, 401 (1979); Rutner, H., et al.: Cancer. Chem. Rep., 58, 803 (1974)

Applications Acridine analog. DNA intercalating agent.
References Hansch, C. et al.: Compr. Med. Chem. 2, 703 (1990)

Applications Acriflavine is an topical antiseptic agent and has also been used for the treatment of external fungal infections. Dyes and metabolites.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Weisman, J.L., et al.: Chem. Biol. Drug. Des., 67, 409 (2006); Sala, C., et al.: Antimicro. Agents. Chemother., 54, 4150 (2010);

Applications Elaiophylin is a macrolide antibiotic with immunosuppresive activity.

Applications A potent phosphodiesterase III A (PDE3A) inhibitor (IC50=0.2uM) and inhibitor of adenosine uptake. Has antimitogeni, antithrombotic, vasodilatory and cardiotonic properties in vivo. Also affects lipid levels in vivo.
References Suri, A., et al.: J. Clin. Pharmacol., 38, 144 (1998), Park, S.-W., et al.: Am. J. Cardiol., 84, 511 (1999), Tsuchikane, E., et al.: Circulation, 100, 21 (1999),

Impurity Levofloxacin USP Related Compound E
Applications Levofloxacin (L360000) impurity. A photodegradation product of Levofloxacin (L360000) in aqueous solution. Levofloxacin USP Related Compound E.
References Yoshida, Y., et al.: Arzneim.-Forsch., 43, 601 (1993),

Applications 4-Tolyl-d4-sulfonamide is the labeled analogue of 4-Tolylsulfonamide (T536630), a carbonic anhydrase inhibitor used the synthesis of antiglaucoma and anticancer drugs.
References Vullo, D. et al.: Bioorg. Med. Chem. Lett., 15, 963 (2005); Vullo, D. et al.: Bioorg. Med. Chem. Lett., 15, 971 (2005);

Applications 1,4-Dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester has been studied as a novel influenza endonuclease inhibitor. They also function as high-affinity ligands at the benzodiazepine site of brain GABAA receptors.
References Baughman, B. et al.: ACS. Chem. Biol., 7, 526 (2012); Gaurav, A. et al.: Medicin. Chem. Res., 20, 192 (2011);

Applications 2-[3-(Trifluoromethyl)phenoxy]nicotinic Acid (cas# 36701-89-0) is a useful reagent for the preparation of difluoroalkylarenes via photocatalytic alkylation of trifluoromethylarenes with alkenes.
References Vogt, D. B., et al.: J. Am. Chem. Soc., 141, 13203 (2019)

Applications Epichlorohydrin is used as a solvent for natural and synthetic resins, gums, cellulose esters and ethers, paints, varnishes, nail enamels and lacquers, cement for Celluloid. Also, it is used as stabilizer.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Smyth, H.F., et al.: J. Ind. Hyg. Toxicol., 30, 63 (1948),

Applications Fenfluthrin can be used in agricultural use and as analyte in analytical/biological study of retrospective screening of relevant pesticide metabolites in food using liquid chromatography high resolution mass spectrometry and accurate-​mass databases of parent molecules and diagnostic fragment ions.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Polgar, L., et al.: J. Chromatogr. A., 1249, 83-91 (2012)

Applications Labelled Ticagrelor (T437700), the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).
References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),

Applications ω-Hydroxy-DEET is a metabolite of DEET (D228500), an insect repellant commonly used to prevent contact with mosquitoes.
References Constantino, L. & Iley, J.: Xenobiotica, 29, 409 (1999); Syed, Z. & Leal, W.: P. Natl. Acad. Sci. USA, 105, 13598 (2008)

Applications Mesotrione is a herbicide that works by inhibiting 4-hydroxyphenylpyruvate dioxygenase (HPPD), a crucial enzyme for the biosynthesis of carotenoid in plants. Mesotrione is also a synthetic analog of lepospermone.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Deng, L., et al.: Indus. Crops. Prod., 39, 154 (2012); Pileggi, M., et al.: Chemosphere., 86, 1127 (2012); McElroy, J., S., Hort. Technol.,22, 627 (2012);

Applications Useful as a therapeutic antimicrobial for the treatment of respiratory infections.
References Pandey, S., et al.: J. Environ. Biol., 14, 267 (1993), Halling-Sorensen, B., et al.: J. Antimicrob. Chemother., 46, 53 (2000), Kim, S., et al.: Environ. Sci. Technol., 41(1), 50 (2007)

Applications Antiemetic, antipsychotic; used in treatment of vertigo.
References Taylor, W.B., et al.: Br. J. Clin. Pharmacol., 23, 137 (1987), Ward, A.E., Br. J. Clin. Pract., 42, 228 (1988),

Applications A reagent used to synthesize various dyes used in the textile industry. This is the labeled analog.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rosenkranz, H.S. et al.: Mutagen., 5, 137 (1990);

Stability Hygroscopic
Applications A metabolite of Deferiprone (D474000).
References Choudhury, R., et al.: Drug Metab. Dispos., 23, 314 (1995),

Applications Platycodin D is a known inhibitor of the proliferation of human gastric cancer cells as well as inducing apoptosis. It also causes anti-atherosclerotic.
References Wu, J. et al.: Biol. Pharm. Bull. 35, 1216 (2012); Chun, J. et al.: J. Cell. Biochem., 114, 456 (2013);

Applications Succinic Acid-1,4-13C2 (cas# 79864-95-2) is a compound useful in organic synthesis.

Stability Very Hygroscopic
Applications Labelled Metaproterenol (M225835). Bronchodilator.
References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971),

Applications 2,2-Difluoro-1,3-benzodioxole-4-carboxylic acid
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Labelled 5-FU, a potent antineoplastic agent in clinical use. Also an inhibitor of DNA synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rudy, B.C., et al.: Anal. Profiles Drug Subs., 2, 221 (1973), Miyashita, O., et al.: Chem. Pharm. Bull., 29, 3181 (1981), Hansen, R.M., et al.: Cancer Invest., 9, 637 (1991),

Stability Hygroscopic
Applications L-Penicillamine Hydrochloride is a salt form of L-Penicillamine (P2230005). L-Penicillamine is a metabolite of penicillin. L-Penicillamine is used in the treatment of Wilson’s disease, Cystinuria, Scleroderma and arsenic poisoning.
References Marti-Prats, L., et al.: Neurosci. Lett., 483, 143 (2010), Singh, A., et al.: J. Pharm. Sci., 99, 3931 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010),

Applications (-)-Carbovir, is a nucleoside/nucleotide reverse transcriptase inhibitor (NRTI) caused mitochondrial toxicity in human hepatoma carcinoma cell.
References Suo, Z., et al.: J. Biol. Chem., 273, 27250 (1998), Ray, A., et al.: Antimicrob. Agents Chemother., 48, 1089 (2004), Lynx, M., et al.: Biochem. Pharmacol., 71, 1342 (2006),

Applications N-Nitrosodiisopropylamine ia a nitrosoamine compound that shows carcinogenic effect.
References Scanlan, R., et al.: Cancer Res., 43, 2435 (1983), Spiegelhalder, B., et al.: Carcinogenesis, 4, 1147 (1983), Lijinsky, W., et al.: Mutat. Res., 443, 129 (1999), Robichova, S., et al.: Chem. Biol. Interact., 148, 163 (2004)

Applications Ketorolac-d5 is a labeled analogue of Ketorolac, a Prostaglandin biosynthesis inhibitor. Analgesic; anti-inflammatory.
References Rooks, W.H., et al.: Agents Actions, 12, 684 (1982); Guzman, A., et al.: J. Med. Chem., 29, 589 (1986); McQuary, H.J., et al.: Clin. Pharmacol. Ther., 39, 89 (1986)

Applications A labelled analog of Lorazepam (L469850). Sedative, hypnotic.Controlled substance (depressant).
References Nudelman, A., et al.: J. Pharma. Sci., 63, 1886 (1974), Humpel, M., et al.: Eur. J. Drug Metab. Pharmacokinet., 4, 237 (1979), Girkin, R., et al.: Xenobiotica, 10, 401 (1980),

Applications Febuxostat-d7, is the labeled analogue of Febuxostat-d7 (F229000), a Xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout.
References Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005),

Stability Hygroscopic
Applications 5-Aminoimidazole-4-carboxamide Lactose Adduct is a lactose adduct of 5-Aminoimidazole-4-carboxamide (A611690), a metabolite of Temozolomide (T017775).
References Jaeken, J., et al.: Lancet, 2, 1058 (1984), Baggott, J., et al.: Biochem. J., 236, 193 (1986), Baggott, J., et al.: Arch. Dermatol., 135, 813 (1999)

Applications Istradefylline is a selective A(2A) antagonist used in the treatment of Parkinson’s disease.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Dungo, R. et al.: Drugs., 73, 875 (2013); Stoessel, A. et al.: J. Med. Chem., 56, 4580 (2013);

Applications Trinexapac-d5, is the labeled analogue of Trinexapac (T886315), a plant growth regulator that studies have shown to have the enzymic activity of histone lysine demethylases and histone modifications during the neural stem/progenitor cell differentiation
References Vavilala, D. et al.: Toxicology Reports, Vol.1, P: 1152-1161 (2014);

Applications zeta-Cypermethrin is used in the season-long insecticide programs for the control of Drosophila suzukii on blackberries of United states. Evaluation of selected insecticides against caterpillar pests in conventional and Bt sweet corn.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Diepenbrock, L. M., et al.: Crop Protection, 98, 149 (2017); Langdon, K. W., et al.: Arthropod Manag. Tests, 37, 60 (2011)

Applications Octocrylene-13C3 is the labelled form of Octocrylene (O239755). Octocrylene is a UV-A and UV-B filter used in sunscreen and topical drug formulations.
References Lacatusu, I. et al.: Chem. Eng. J., 246, 311 (2014); Allen, J. et al.: Chem. Res. Tox., 9, 605 (1996)

Applications Labelled tricyclic antidepressant that is a more potent inhibitor of the norepinephrine transporter than the serotonin transporter.
References Checkley, S.A, et al.: Br. J. Psychiatry, 138. 248 (1981), Zhu, M.Y., et al.: J. Neurochem., 70, 1547 (1998), Okugawa, G., et al.: J. Neuroindocrinol., 11, 887 (1999), Torres, G.E., et al.: Nat. Rev. Neurosci., 4, 13 (2003),

Applications Labelled Tolfenamic Acid. Non-steroidal anti-inflammatory drugs (NSAIDs). A derivative of anthranilic acid, related structurally to Mefenamic and Flufenamic acids. Anti-inflammatory, analgesic.
References Pentikaeinen, P., et al.: Eur. J. Clin. Pharmacol., 19, 359 (1981), Bundscherer, A., et al.: Oncol. Rep., 19, 547 (2008), Elwood, P., et al.: Lancet, 373, 1301 (2009),

Applications Benzyldecyldimethylammonium Chloride is a biocide.
References Lee, M., et al.: Appl. Micro. Biotech., 87, 1109 (2010); Campanac, C., et al.: Antimicrob. Agents Ch., 46, 1469 (2002); Shen, J., et al.: Anal. Chem., 62, 116 (1990)

Applications O-Desethyl Dapagliflozin is derivative of antidiabetic drug Dapagliflozin (D185370), which is sodium-glucose transporter 2 inhibitor.
References Kasichayanula, S., et al.: Diabetes, Obesity and Metabolism 13, 47 (2011); Xu, G., et al.: J. Med. Chem., 57, 1236 (2014);

Applications trans-Permethrin is the trans isomer of Permethrin (P288500) which is a common synthetic pyrethoid insecticide with low mammalian toxicity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Itaya, N., et al.: ACS Sym. Ser., 42, 45 (1977); Elliott, M., et al.: Nature, 246, 169 (1973);

Applications Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
References Kim, D., et al.: J. Med. Chem. 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol. 521 164 (2005), Bergman, A., et al: Clin. Ther. 28, 55 (2006)

Stability Hygroscopic
Applications Labelled analogue of Cloxacillin, an antibiotic that belongs to the group of the isoxazolylpenicillins. Cloxacillin is used to treat infections caused by species of staphylococci that produce beta-lactamase due to its inhibitory effects on beta-lactamase binding.
References Gibbs, D.L. et al.: Curr. Microbiol., 2, 239 (1979); Dmitrova, D. et al.: Farmat., 48, 28 (2001); Craven, N. et al.: Res. Vet. Sci., 29, 57 (1980);

Applications Mandestrobin is a novel fungicide having a methoxyacetamid structure. Mandestrobin also shows safer profiles for human health and the environment.
References Hirotomi, D., & Kiguchi, S.: PCT Int. Appl., WO 2017026526 A1 20170216 (2017)

Applications 2,6-Dichloro-4-(trifluoromethyl)aniline is used in the synthesis of GABA receptor antagonists and insecticides.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sammelson, R. et al.: Bioorg. Med. Chem., 12, 3345 (2004); Huang, W. et al.: Bioorg. Med. Chem., 14, 8280 (2006);

Applications 2,4-Dichlorophenol-13C6 is the labelled analog of 2,4-Dichlorophenol (D435685). 2,4-Dichlorophenol is a chlorinated derivative of phenol and is used as an intermediate for the preparation of herbicide 2,4-dichlorophenoxyacetic acid (D435680).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhong, W., et al.: J. Hazard. Mat., 217, 286 (2012); Rowe, V.K., et al.: Am. J. Vet. Res., 15, 622 (1954), Way, J.M., et al.: Residue Rev., 26, 37 (1969)

Applications Pyridaben is a pyridazinone derivative used as an insecticide and acaricide. In the European Union, Pyridaben has been authorized for use as an insecticide and acaricide from 1 May 2011. In Germany, Austria and Switzerland, no plant protection products containing this active substance are authorized. Pyridaben is a colorless solid that is practically insoluble in water. Useful in cannabis testing kits as a component of pesticide mixes (P698235).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wadleigh, R., et al.: J. Chem. Ecol.,14, 1279 (1988), Hirata, K., et al.: J. Pestic. Sci., 20, 177 (1995), Chen, F., et al.: J. Entomol. Sci., 42, 296 (2007),

Stability Hygroscopic
Applications Found in many plants, especially the buckwheat plant. Identity with Ilixanthin. Capillary protectant. Rutin is colored brown by tobacco enzyme under experimental conditions.
References Harrison, et al.: J. Am. Pharm. Assoc., 39, 557 (1950), Humphreys, et al.: Econ. Bot., 18, 195 (1964), Khalifa, T.I., et al.: Anal. Profiles Drug Subs., 12, 623 (1983).

Applications Tembotrione is one of the pesticides found in surface waters. It can also be found as pesticide residues in fruits and vegetables.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Moschet, C., et al.: Environ. Sci. Technol., 48, 5423 (2014); Wang, J., et al.: J. Agric. Food Chem., 62, 10375 (2014);

Applications Flusilazole is a silicon-containing triazole fungicide. Flusilazole is used to control fungal infections on a variety of fruit and vegetable crops
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Moberg, W.K. et al.: Biol. Act. Organosil. Comp., 355, 288 (1987); Bostanian, N.J. et al.: Pest. Man. Sci., 57, 1007 (2001); Eckert, M.R. et al.: Pest. Man. Sci., 66, 396 (2010);

Applications 2,3,5-Trichloropyridin-4-amine (cas# 28443-69-8) is a useful research chemical.

Applications A metabolite of Chlorpyrifos (C425300).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Barron, M.G., et al.: Environ. Toxicol. Chem., 12, 1469 (1993), Tang, J., et al.: Drug Metab. Dispos., 29, 1201 (2001),

Applications Labelled antilipemic.
References Fuccella, L.M., et al.: Clin. Pharmacol. Ther., 28, 790 (1980), Lovisolo, P.P., et al.: Pharmacol. Res. Commun., 13, 151 (1981), Aktories, K., et al.: Arzneim.-Forsch., 33, 1525 (1983), Boatman, P., et al.: J. Med. Chem., 51, 7653 (2008), Rigazio, S., et al.: Am. J. Physiol., 295, E413 (2008),

Applications A labeled metabolite of Diosmetin (D485000) isolated and identified from Chrysanthemum morifolium L. v. Ramat leaves.
References Porra, R., et al.: Biochem. Biophys Acta, 975, 384 (1989), Watanabe, M., et al.: J. Agric. Food Chem., 47, 4500 (1999),

Applications (aS,bR)-Bedaquiline is a diarylquinoline derivative that acts as a mycobacterial inhibitor. Bedaquiline shows promise as potential drug in the treatment of tuberculosis.
References Cheepsattayakorn, A., et al.: Anti-Infect. Drug. Discover.,7, 141 (2012); de Jonge M.R. et al.: Proteins, 67, 971 (2007); Diacon A.H. et al.: N. Eng. J. Med., 360, 2397 (2009);

Applications Ibogaine Hydrochloride is a naturally occurring psychoactive substance. It is a β-carboline derivative that cause both hallucinations and tremor.
References O’Hearn, E., et al.: Neurosci., 55, 303 (1993)

Applications Tecloftalam Imide is a derivative of Tecloftalam (T013700), an agrochemical fungicide. Tecloftalam is used for the control of rice bacterial leaf blight.
References Nakagami, K. et al.: Nip. Noyak. Gak., 5, 511 (1980); Kirkpatrick, D. et al.: J. Agric. Food Chem., 29, 608 (1981); Takahi, Y. et al.: Jap. Past. Info., 46, 25 (1985);

Applications Labelled derivative of Artemisinin. Antimalarial.
References Zhao, Y., et al.: J. Nat. Prod., 49, 139 (1986), Lin, A.J., et al.: J. Med. Chem., 30, 2147 (1987), Price, R. N., et al.: Expert Opin. Invest. Drugs, 9, 1815 (2000),

Applications Isoprinosine is a new combination of active substances for the treatment of chronic systemic diseases such as cancer. Isoprinosine is an immunomodulator; antiviral. The ratio is between 1: 2 : 2 to 1 : 3 : 3
References Mastino, A., et al.: Int. J. Cancer, 50, 493 (1992), Kim, Y., et al.: Mol. Cancer Therap., 8, 469 (2009),

Applications A triazinetrione anticoccidial. Coccidiostat.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Eberts, T., et al.: Clin. Chem., 25, 1440 (1979), Goodwin, M., et al.: Avian Dis., 29, 630 (1985), Sorensen, S., et al.: Clin. Chim. Acta, 264, 103 (1997), Conway, D., et al.: Poult. Sci., 280, 426 (2001),

Applications Oxamyl is a pesticide used in the treatment and protection of crops from parasites and insects. Oxamyl is also useful in cannabis testing kits as a component of pesticide mixes (P698240).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications A Nicotine metabolite. Carcinogen.

Applications Quintrione is herbicidal compound comprising Heterocyclic Amide compound and use thereof.
References Wang, Z., et al.:PCT Int. Appl., (2020);

Applications trans-2-Decenoyl-L-carnitine is a metabolite of L-Carnitine (C184110), which is a essential cofactor of fatty acid metabolism; required for the transport of fatty acids through the inner mitochondrial membrane. Synthetized primarily in the liver and kidney; highest concentrations found in heart and skeletal muscle. Dietary sources include red meat, dairy products, beans, avocado.
References Mitchell, M.E., et al.: Am. J. Clin. Nutr., 31, 293 (1978), Lango, R., et al.: Cardiovasc. Res., 51, 21 (2001), Vaz, F.M., et al.: Biochem. J., et al.: 361, 417 (2002), Karlic, H., et al.: Nutrition, 20, 709 (2004),

Stability Hygroscopic
Applications Anorexic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Pinder, et al.: Drugs, 10, 241 (1975), Caccia, S., et al.: Eur. J. Clin. Pharmacol., 29, 221 (1985), Finner, N., et al.: Curr. Ther. Res., 38, 847 (1985),

Stability Very Hygroscopic
Applications The major metabolite of herbicidal Glufosinate (G596950).

Stability Unstable in Protic Solvent
Applications Cefalonium is a first-generation cephalosporin antibiotic used as a long-acting intramammary cerate for infusion of dairy cows.
References Endo, T.: Kach. Kokin. Kenk., 12, 8 (1991); Berry, E.A. et al.: J. Dairy Sci., 90, 760 (2007); Bradley, A.J. et al.: J. Dairy Sci., 93, 1566 (2010);

Applications Isotope labelled 24 Bisphenol S (B519620) is a material used in thermal printing. 24 Bisphenol S is also used in the development of black leuco dyes.
References Shima, H. et al.: J. Imag. Sci. Technol., 54, 020502 (2010)

Applications N2-(1-Ethylpropyl)-4,5-dimethyl-3-nitro-1,2-benzenediamine is a metabolite of Pendimethalin (P221900), an herbicide used to control the spread of weedgrass.
References Haith, D., et al.: Environ. Sci. Technol., 44, 6496 (2010); Jabran, K., et al.: Int. J. Agric. Biol., 12, 335 (2010); Rahaman, S., et al.: Environ. Ecol., 28, 1 (2010); Smith, R.H., et al.: Chemosphere, 8, 855-61 (1979);

Applications Cetrimonium Chloride, is a topical antiseptic. It is also used in hair conditioners and shampoos, as a conditioning agent
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zahang, M. et al.: Zoazhi Huaxueoin, 24, 13 (2012);

Applications Enrofloxacin-d5 is a labelled fluorinated quinolone antibacterial.
References Altreuther, P., et al.: Vet. Med. Rev., 2, 87 (1987),

Applications Tebutam is used as herbicide and pesticide.