Toxicologie

Applications Desmedipham is a carbanilate based herbicide used in the weed control programs in sugar beet.
References Kittlaus, S., et al.: J. Chromatograph. A., 1283, 98 (2013); Wujek, B., et al.: J. Food. Agri. Environ., 10, 606 (2012);

Stability Hygroscopic
Applications Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).
References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),

Applications Thifluzamide is a fungicide found in cereals, vegetables and fruits; A succinate dehydrogenase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cui, C., et al.: Sepu, 35, 487-494 (2017); Sun, H., et al.: Pest Manag. Sci., 73, 896-903 (2017)

Applications Chlorfenapyr-d7 is the labelled analogue of Chlorfenapyr (C428500), which is a halogenated pyrrole based pro-insecticide. Chlorfenapyr functions by metabolizing into an active insecticide after entering the host. Chlorfenapyr is used primarily as a means of pest control on cotton. Used as a standard for Pesticide detection. Chlorfenapyr is also useful in cannabis testing kits as a component of pesticide mixes (P698230).
References Lovell, J.B. et al.: Bright. Crop Prot. Pests Dis., 1, 37 (1990); Wier, A.T. et al.: J. Agric. Entemol., 11, 311 (1994); Black, B.C. et al.: Pest. Biochem. Physiol., 50, 115 (1994);

Applications 6-amino-5-chloro-2-cyclopropylpyrimidine-4-carboxylic Acid (cas# 858956-08-8) is a useful research chemical.

Applications Strobilurin fungicide; inhibits mitochondrial respiration by blocking electron transfer between cytochromes b and c1. Agricultural fungicide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Smalling, K., et al.: Environ. Toxicol. Chem., 29, 2593 (2010), Lu, X., et al.: Phytopathol., 100, 1162 (2010), Schafer, R., et al.: Environ. Sci. Technol., 45, 1665 (2011),

Applications Rimsulfuron is used as a pesticide.
References Pennington, D., et al.: Environ. Sci. Technol., 39, 1119 (2005), Wang, S., et al.: Food Control., 18, 731 (2007), Wolters, A., et al.: Sci. Total Environ., 405, 269 (2008),

Stability Hygroscopic, Light Sensitive
Applications Insect repellent.
References Gilbert, I.H., et al.: J. Econ. Entomol., 48, 741 (1955), Ambrose, A.M., et al.: Toxicol. Appl. Pharmacol., 1, 97 (1959), Blomquist, L., Acta Pharmacol. Toxicol., 41, 235 (1977), Yeung, J.M., et al.: Drug Metab. Dispos., 16, 600 (1988),

Stability Light Sensitive
Applications Acrylonitrile_x000D_(stabilized with 35-45 ppm 4-hydroxy anisole (H750015)) (cas# 107-13-1) is a compound useful in organic synthesis.
E0

Applications Bis(butoxyethyl) Phosphate is used in biological studies as a metabolism of phosphate flame retardants and plasticizers using human liver fractions.
References Van den Eede, N., et al.: Toxicol. Lett., 223, 9 (2013)

Impurity Levothyroxine EP Impurity D / T4-Acetic Acid (USP)
Applications Thyroid hormone analogue. A potent Thyroxine impurity. T4-Acetic Acid (USP).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Horst, C., et al.: Biochem. J., 261, 945 (1989), Kvetny, J., et al.: Horm. Metab. Res., 24, 322 (1992), Yamauchi, K., et al.: J. Biol. Chem., 274, 8460 (1999), Davis, P., et al.: J. Endocrinol. Invest., 25, 377 (2002),

Applications Used for oral gel patch or film containing herb extracts or Chinese medicine, fruit extract, spearmint, and menthol for smoking cessation.
References Gillet, Y., et al.: Lancet, 359, 753 (2002), Turos, E., et al.: Bioorg. Med. Chem. Lett., 2002, 12, 2229 (2002),

Applications Deguelin exhibits potent apoptotic and antiangiogenic activities in a variety of transformed cells and cancer cells. Deguelin also exhibits potent tumor suppressive effects in xenograft tumor models for many human cancers.
References Chang, D.J.. et al.: J. Med. Chem., 55, 10863 (2012);

Applications Used as insecticide for terminate control; pre-harvest defoliant; general herbicide. Antimicrobial preservative and fungicide for wood, wood products, starches, textiles, paints, adhesives, leather, pulp, paper, industrial waste systems, building materials; Surface disinfectant. Exposure to PCP is also associated with carcinogenic, renal, and neurological effects. This compound is a contaminant of emerging concern (CECs). One of the new POPs under the Stockholm Convention
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gaines, T.B., et al.: Toxicol. Appl. Pharmacol., 14, 515 (1969),

Applications A steroid used as a probe in the detection of different viruses.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lin, L. et al., J. Virol. Methods, 171, 91 (2010); Finnegan, C.J. et al., J. Virol. Methods, 121, 223 (2004); Rubio, L. et al., J. Virol. Methods, 114, 105 (2003)

Applications Isotope labelled Resiquimod (R144680) is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.
References Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008);