Toxicologie

Stability Hygroscopic
Applications Labelled Vildagliptin. It is a new oral anti-hyperglycemic agent of a new dipeptidyl peptidase-IV (DPP-IV) inhibitor class of drugs. Antidiabetic.
References Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004), Ahren, B., et al.: Diabetes Care, 27, 2874 (2004), Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),

Stability Light Sensitive
Applications An impurity of Minocycline (M344800). Used in the preparation of calpain inhibitors.
References Sokoloski, T.D., et al.: J. Pharm. Sci., 66, 1159 (1977), Naidong, W., et al.: J. Pharm. Biomed. Anal., 13, 905 (1995),

Stability Hygroscopic
Applications Anesthetic (local); antiarrhythmic (class IB). Long-acting, membrane stabilizing agent against ventricular arrhythmia. Originally developed as a local anesthetic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Duce, R., et al.: J. Pharmacol. Exp. Ther., 179, 580 (1971), Kronberg, G.H., et al.: J. Med. Chem., 16, 739 (1973), Groningsson, K., et al.: Anal. Profiles Drug Subs., 14, 207 (1985), Davies, P.S., et al.: Drugs, 64, 937 (2004),

Applications Daminozide is a plant growth regulator used to improve crop quality and maximize yield.Used as a standard for Pesticide detection. Useful in cannabis testing kits as a component of pesticide mixes (P698240).
References Xiaoming, R., et al.: Field Crops Res, 149, 1-10 (2013)

Stability Hygroscopic
Applications A metabolite of Bufuralol, a β-Adrenergic blocker with peripheral vasodilating activity.
References Boobis, A.R., et al.: Biochem. Pharmacol., 34, 65 (1985), Yamazaki, H., et al.: Mol. Pharmacol., 46, 568 (1994), Mast, N., et al.: Biochem., 42, 14284 (2003),

Applications Labelled Gefitinib (G304000). Gefitinib is an antineoplastic.
References Anderson, N.G., et al.: Int. J. Cancer, 94, 774 (2001), Hirata, A., et al.: Cancer Res., 62, 2554 (2002), Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003), Tamura, K., et al.: Expert Opin. Pharmacother., 6, 985 (2005),

Applications Sulfacetamide-d4 is the isotope labelled analog of Sulfacetamide. Sulfacetamide is an antibiotic used for the treatment of skin infections and urinary tract infections. Sulfacetamide is also used to treat acne and seborrheic dermatitis. Sulfacetamide was investigated for potential anti-inflammatory properties
References Wittwer, M.B., et al.: J. Med. Chem., 56, 781 (2013); Wang. X., et al.: Afr. J. Micriobiol., 6, 4533 (2012); Yu, B., et al.: Euro. J. Med. Chem., 46, 5833 (2011);

Applications Isotope labelled penconazole is an conazole based fungicide that works by inhibiting cell membrane ergosterol biosynthesis, thus stopping the development of fungi.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sharma, H., et al.: J. Mycol. Plant. Pathol., 42, 494 (2012); Sen, K., et al.: Food. Chem. Toxicol., 50, 3990 (2012); Pitt, W.M., et al.: Plant Disease., 96, 1303 (2012);

Applications Post-emergence sulfonylurea herbicide.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gubbiga, N.G., et al.: Weed Technol., 9, 574 (1995), Ukrainczyk, L., et al.: J. Agric. Food Chem., 43, 855 (1995)

Applications Isotope labelled Diethyl Oxalate is used in the synthesis of novel indole β-diketo acid derivatives as HIV-1 integrase inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sechi, M., et al.: J. Med. Chem., 47, 5298 (2004);

Applications A deuterated prodrug of Penciclovir (P221500), which is used as an antiviral.
References Hodge, V.R.A., et al.: Antimicrob. Ag. Chemother., 33, 1765 (1989),

Applications It is a bisbiguanide with bacteriostatic activity. Antiseptic; disinfectant.
References Davies, G.E., et al.: Br. J. Pharmacol., 9, 192 (1954), Foulkes, D.M., et al.: J. Periodontal Res., 8, 55 (1973),

Applications Phenethylamine-d4 is labelled phenethylamine (P321335) which is a psychoactive drug and stimulant that affects dopamine levels. It uses a mechanism of inverse agonism at the D2 dopamine receptor to achieve this effect. Phenylethylamine (P321335) functions as a neuromodulator or neurotransmitter in the mammalian central nervous system.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wilson, J. et al.: J. Neurochem., 77, 493 (2001); Sotnikova, T. et al.: J. Neurochem., 91, 362 (2004); Schmitt, K. et al.: J. Neurochem., 112, 1605 (2010); Sabelli, H., et al.: Biol. Psychiat., 11, 481 (1976)

Applications Benzovindiflupyr can be used in biological study of method to predict and understand fish survival under dynamic chemical stress using standard ecotoxicity data. Useful in cannabis testing kits as a component of pesticide mixes (P698240).
References Ashauer, R., et al.: Environ Toxicol Chem., 32, 954-965 (2013)

Applications Ethiprole is a phenylpyrazole based insecticide used in rice ecosystem on Trichogramma japonicum, and egg parasitoid of rice lepidopterans.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhao, X.P., et al.: J. Economic. Entomol., 105, 92 (2012); Gomez-P. M.L., et al.: J. Chromatograph. A., 1248, 130 (2012);

Stability Hygroscopic
Applications An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.
References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),

Applications Flecainide is an antiarrhythmic (class IC).
References Hodess, A.B., et al.: J. Cardiovasc. Pharmacol., 1, 427 (1979), Somani, P., et al.: Clin. Pharmacol. Ther., 27, 464 (1980), Alessi-Severini, S., et al.: Anal. Profiles Drug Subs. Excip., 21, 169 (1992)

Applications Demeton-O is an organophosphorus pesticide found in some imported crops and fruits samples.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zvinavashe, E., et al.: Chemosphere, 75, 1531 (2009); Kobayashi, M., et al.: Shokuhin Eiseigaku Zasshi, 50, 261, (2009); Tamura, Y., et al.: Tokyo-to Kenko Anzen Kenkyu Senta Kenkyu Nenpo, 59, 199 (2009); Xu, H., et al.: Shijie Nongyao, 29, 42 (2007)

Applications Labelled Pioglitazone (P471000), which is used as an antidiabetic.A representative lot was 87% d4, 12% d3 no d0.
References Hofmann, C., et al.: Endocrinology, 129, 1915(1991), Kobayashi, M., et al.: Diabetes, 41, 476 (1992), Kawaamori, R., et al.,: Diabetes Res. Clin. Pract., 41, 35 (1998)

Applications Moxifloxacin is an antibiotic for the treatment of bacterial infections like bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.
References Zhang, H., et al.: Linchuang Junyi Zazhi, 43, 182 (2015); Fernandes, M. J., et al.: Chemosphere, 239, 124729 (2020); Yilancioglu, K., et al.: Sci. Rep., 9, 1 (2019)

Applications An angiotensin-converting enzyme (ACE) inhibitor.

Applications A long-acting β2 adrenoreceptor agonist and bronchodilator, for the treatment of asthma and chronic obstructive pulmonary disease.
References Currie, G.P. et al.: Curr. Opin. Invest. Drugs., 7, 457 (2006); Naline, E. et al.: Eur. Resp. J., 29, 575 (2007); Roig, J. et al.: Open Resp. Med. J., 3, 27 (2009);

Applications Glycochenodeoxycholic-d5 Acid-3-O-β-glucuronide Disodium Salt is an isotope labelled compound of Glycochenodeoxycholic Acid-3-O-β-glucuronide Disodium Salt (G641275), used in steriod studies and also in the synthesis of conjugated and unconjugated bile acids.
References Goto, J., et al.: Chem. Pharm. Bull., 28, 1258 (1980)

Applications α-Cypermethrin is a synthetic pyrethroid pesticide used in large-scale commercial agricultural applications as well as in consumer products for domestic purposes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Shen, M.F., et al.: Ecotoxiocol. Envrion. Safe., 78, 9 (2012); Baker, N.J., et al.: Sci. Total. Envrion., 449, 150 (2013);

Applications Etodroxizine is a piperazine antihistimine.
References Wolffgramm, J. et al.: Arzneim.-Forsch., 38, 885 (1988); Maurer, H. et al.: Fres. Zeitsch. Anal. Chem., 331, 744 (1988);

Applications An androgen-anabolic steroid.
References Schubert, K. et al.: Endokrinologie 59, 99 (1972)

Applications Histrelin is a gonadotropin releasing hormone analog used with the potential to improve height prospects.
References Brauner, R. et al.: Nat. Rev. Endocrinol., 11, 386 (2015);

Applications 2-Ethylhexyl Salicylate-d4 is an isotopic analog of 2-Ethylhexyl Salicylate (E918775), a skin penetration enhancer that increases drug diffusivity in the skin that has been used in sunscreen products.
References Santos, P., et. al.: Int. J. Pharmaceut., 439, 260 (2012); Rigon, R.B., et. al.: Int. J. Pharm. Pharmaceut. Sci., 5, 306 (2013)

Stability Moisture Sensitive
Applications A cholinesterase inhibitor.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Pickering, W.R., et al.: Biochem. Pharmacol., 16, 1183 (1967)

Applications Procaine is a sodium channel blocker and inhibitor of a variety of processes.

Applications Nandrolone-13C2 Benzoate is the isotope analog of Nandrolone Benzoate. Nandrolone Benzoate is a steroid that has effect on gondatropin and muscles, which is derived from Nandrolone (an anabolic steroid).
References Lerner, L.J., et al.: Endocrinology, 64, 1010 (1959); Gradeen, C., et al.: J. Anal. Toxicol., 14, 120 (1990); Teale, P., et al.: Biol. Mass Spectrom., 20, 109 (1991); Yamada, M., et al.: J. Pharm. Biomed. Anal., 45, 125 (2007); Yamada, M., et al.: J. Anal. Toxicol., 32, 387 (2008)

Applications Chrysanthemic Acid is an intermediate in the synthesis of Chrysanthemic Acid (C903440); Dimethrin is a pesticide, a pyrethroid insecticide. An acaricide for agricultural purposes.
References Ford, M G.: Pestic. Sci., 10, 39 (1979); Gan, W., et al.: Zhonghua Yufang Yixue Zazhi, 35, 13 (2001); Wright, F. C.: Southwestern Entomol., 5, 222 (1980);

Applications L-erythro-Chloramphenicol functions as a potent inhibitor of electron transport in the mitochondria in biological studies. The L-isomer can be identified from the other CAP-isomers through reversed phase and chiral liquid chromatography in combination with tandem mass spectrometric detection.
References Berendsen, B., et al.: Anal. Chim. Acta., 700, 78 (2011), Wilson, S.B., et al.: Biochim. Biophys. Acta., 292, 603 (1973)

Applications (1S,2R)-2-((Benzyloxy)methyl)cyclopent-3-enol is an intermediate in the synthesis of Entecavir (E558900), an oral antiviral drug used in the treatment of hepatitis B infection.
References Gathergood, N., et al.: J. Org. Chem., 66, 1014 (2001);

Applications Cuprolinic Blue, has been shown to be able to form a particularly stable blue chromophore with single-stranded RNA in neuronal Nissl substance and nucleoli, and thus can be used for counterstaining of enteric neurons for peroxidase immunocytochemistry
References Holst, M., et al.: J. Neurosci., Meth., 62, 121 (1995);

Applications Olivetol-d9 is a precursor in various syntheses of labelled tetrahydrocannabinols.
References Kumano, T., et al.: Bioorg. Med. Chem., 16, 8117 (2008), Appendino, G., et al.: J. Nat. Prod., 71, 1427 (2008), Sampietro, D., et al.: Food Chem., 115, 1170 (2009),

Applications Fluorinated quinolone antibacterial. An enantiomer of Levofloxacin (L360000).
References Hwangbo, H.J. et al.: Eur. J. Pharmac. Sci., 18, 197 (203); Gascon, A.R. et al.: J. Clin. Pharmacol, 40, 869 (2000); Monk, J.P., et al.: Drugs, 33, 346 (1987); Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990);

Applications An active metabolite of Glimepiride.
References Muller, G., et al.: Diabetes, 42, 1852 (1993), Kramer, W., et al.: Biochem. Biophys. Acta, 119, 278 (1994),

Applications rac Fosfomycin-13C3 Benzylamine Salt is an antibiotic.
References Goto, M., et al.: Antimicrob. Agents Chemother., 20, 393 (1981);

Applications Ribavirin-13C2 is the labeled analogue of Ribavirin (R414475), a purine nucleoside analog; inhibits inosine monophosphate dehydrogenase (IMPDH). Used as an antiviral agent.This compound is suitable for pyruvate dehydrogenase (PDH) related research.
References Fernandez, H., et al.: Eur. J. Epidemiol., 2, 1 (1986); Liao, H.J. and Stollar, V.: Antiviral Res., 22, 285 (1993); Honda, Y., et al.: Antimicrob. Agents Chemother., 38, 653 (1994); Reichard, O., et al.: Lancet, 351, 83 (1998)

Applications Lufenuron is a benzoylurea pesticide which inhibits the production of chitin in larval fleas.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Dryden, M.W.,et al.: Int. J. App. Res. Veterrin. Med., 10, 198 (2012); Malhat, F., et al.: Bull. Environ. Contamin. Toxicol., 89, 1037 (2012);

Applications Quizalofop-p-tefuryl solution
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Pyruvic Acid-13C2 is an intermediate in synthesizing L-Lactic Acid-d3 Sodium Salt (L113503), a labelled sodium salt of L-Lactic Acid (L113500). L-Lactic Acid occurs in small quantities in the blood and muscle fluid of man and animals. The lactic acid concentration increases in muscle and blood after vigorous activity. L-(+)-Lactic acid is also present in liver, kidney, thymus gland, human amniotic fluid, and other organs and body fluids.
References Wenzel, A., et al.: J. Neurosci., 21, 53 (2001); Martinez., et al.: Development, 6, 851 (2002); Nakayama, K., et al.: J. Biochem., 146, 757 (2009); Tanaka, T., et al.: J. Pharmacol. Sci., 109, 24 (2009)

Applications 3-Ketocarbofuran is a metabolite of Carbofuran (C176590). A pesticide residue found in fruits and vegetables. 3-Ketocarbofuran causes cell migration in cell gel electrophoresis (SCGE) test.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Abass, K., et al.: Chem-Biol. Interact., 18, 210 (2009); Ambrus, A., et al.: J. Environ. Sci. Heal. B., B40, 297 (2005); Usmani, K., et al.: Chem-Biol. Interact., 150, 221 (2004)

Applications Phorate Sulfone is a metabolite of Phorate (85%, P353500) which is a non-biocumulative organophosphate used as an insecticide and acaricide. Phorate is an inhibitor of acetylcholinesterase and pseudocholinesterase.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Pandey, G.C. et al.: Ind. J. Comp. Anim. Physiol., 6, 1 (1988); Henderson, M.C. et al.: Biochem. Pharmacol., 68, 959 (2004); Peter, J.V. et al.: NeuroToxicology, 29, 335 (2008);

Applications A metabolite of Estradiol.
References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985), Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991), Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998), Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000),

Impurity Mometasone Furoate EP Impurity D
Applications A21-Chloro-17α-[(2-furanylcarbonxyl)oxy]-9β,11β-oxido-16α-methylpregna-1,4-diene-3,20-dione (Mometasone EP Impurity D) is a impurity of Mometasone Furoate.
References Shapiro, E.L., et al.: J. Med. Chem., 30, 1581 (1987), Graft, D., et al.: J. Allergy Clin. Immunol., 98, 724 (1996)

Stability Material darkens in storage with no loss in purity
Applications 3-Chlorobenzenamine is used in the synthesis of pyrimidoazepine analogs as serotonin 5-HT2A and 5-HT2C receptor ligands for the treatment of obesity. Also used in the synthesis of novel COX-2 inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yang, H. et al.: Eur. J. Med. Chem., 63, 558 (2013); Penning, T. et al.: J. Med. Chem., 40, 1347 (1997);

Applications 3-Indolepropionic acid is a deamination product of Tryptophan (T947200) that protects the hippocampus (studied in gerbils) from ischemic damage and oxidative stress. It’s ability to protect the neurons in this way is attributed to its potent antioxidative effects. 3-Indolepropionic acid is also hypothesized to have protective effects on the thyroid gland.
References Hwang, I., et al.: J. Neurosci. Res., 87, 2126 (2009); Karbownik, M., et al.: J. Cell. Biochem., 95, 131 (2005)

Applications Antidyskinetic; antipsychotic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Janicki, C.A., et al.: Anal. Profiles Drug Subs., 9, 341 (1980), Beresford, R., et al.: Drugs, 33, 31 (1987)

Applications Profluthrin is a pyrethroid based insecticide. Profluthrin is an active ingredient found in moth proofer.
References Ujihara, K., et al.: Sumit. Kag., 2, 13 (2010);

Applications L-(-)-Carnitinamide chloride is can be employed as a bactericide. The compound is derived from L-Carnitine (C184110) which is used to prevent and treat a lack of carnitine.
References Pallavicini, Marco., et al.: Tetrahedron: Asymmetry., 18, 906-909 (2007); Vaz, F.M., et al.: Biochem. J., et al.: 361, 417 (2002), Karlic, H., et al.: Nutrition, 20, 709 (2004),

Applications Movento is a synergistic insecticide. Useful in cannabis testing kits as a component of pesticide mixes (P698240).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Byrne, F., et al.: Crop. Prot., 25, 831 (2006), Kanrar, B., et al.: Bull Environ. Contam. Toxicol., 77, 631 (2006), Venkateswarlu, P., et al.: Food Chem., 105, 1760 (2007), Khay, S., et al.: Biomed. Chromatogr., 22, 581 (2008),

Applications An oral antiviral drug used in the treatment of hepatitis B infection. A guanine analogue that inhhibits all three steps in the viral replication process.
References Innaimo, S.F., et al.: Antimicrob. Agents Chemother., 41, 1444 (1997), Honkoop, P., et al.: Expert Opin. Invest. Drugs, 12, 683 (2003), Chang, T.-T., et al.: N. Engl. J. Med., 354, 1001 (2006),

Applications Sodium salt of Penicillin G, an antibacterial, antimicrobial medication. Used in the treatment of pneumococcus and streptococcus bacterial infections.
References Tanaka, M. et al.: Antimicrob. Agents Chemother., 49, 88 (2005); Song, J. et al.: Epidemio. Infect., 140, 1267 (2012); Gamella, M. et al.: Analyst, 138, 2013 (2013);

Applications Aclarubicin is an anthracycline antibiotic. It is used in the treatment of cancer.
References Magi, S., et al.: J. Antibiot., 66, 165 (2013); Wakabayashi, I., et al.: Biochem. Pharmacol., 59, 719 (2000); Viadro, M., et al.: Antibiot Khimioter, 36, 20 (1991);

Applications Propargite is a pesticide used to control mite and is used on various crops from cotton to corn.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hou, X., et al.: Food. Chem., 138, 1198 (2013); Meena, N.K., et al.: Pestol., 36, 40 (2012);

Applications An aryloxyphenoxypropionate (AOPP) post-emergence herbicide that shows an exclusive whole plant safety to rice with a high control efficacy to annual grass weeds, especially barnyardgrass.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Doroh, M.C. et al.: Weed Technol., 26, 97 (2011); Zeng, Z. et al.: Nongyao, 43, 327 (2004); Kim, T.J. et al.: Cong. Proc. BCPC Int. Cong. Crop Sci. Technol., 2, 833 (2003);

Applications A labelled dihydropyridine calcium channel blocker. It is used as a vasodilator (cerebral).
References Allen, G.S., et al.: N. Engl. J. Med., 308, 619 (1983), Schluter, H.: Arzneim.-Forsch., 36, 1733 (1986), Deyo, R.A., et al.: Science, 243, 809 (1989),

Applications Clindamycin is a semi-synthetic antibiotic. Antibacterial.
References Birkenmeyer, R.D., et al.: J. Med. Chem., 13, 616 (1970); Oesterling, et al.: J. Pharm. Sci., 59, 63 (1970); Gray, J.E., et al.: Toxicol. Appl. Pharmacol., 21, 516 (1972); Brown, L.W., et al.: Anal. Profiles Drug Subs., 10, 75 (1981);

Applications Hexadecyltrimethylammonium Bromide (CTAB) is a cationic surfactant used as a template in the synthesis of Mesoporous γ-Fe2O3.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yu, H.-h., et al.: Gongneng Cailiao, 42, 2005 (2011),

Applications Labelled Neratinib (N390090). An oral, irreversible dual EGFR/HER2 inhibitor for breast and non-small cell lung cancer. Antitumor agent.
References Vogel, C., et al.: J. Clin. Oncol., 20, 719 (2002), Ji, H., et al.: Cancer Cell., 9, 485 (2006), Sequist, L., et al.: Oncologist, 12, 325 (2007),

Applications A labelled Chloroquine metabolite, also an intermediate in the preparation of labelled Chloroquine It is a COVID19-related research product.
References Brown, N., et al.: J. Chromatogr., Biomed. App., 309, 426 (1984), Nord, K., et al.: Int. J. Pharm., 72, 11 (1991),

Applications Endosulfan is an insecticide that poses health risks to humans and animals that acquire it through ingestion, inhalation, and percutaneous contact. Despite its potential risks, it is still being widely used all around the globe to protect cotton, sugarcane, and vegetable crops.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bhalerao, T. & Puranik, P.: Int. Biodeter. Biodegr., 59, 315 (2007); Kalender, S., et al.: Toxicology, 202, 227 (2004); Naqvi, S. & Vaishnavi, C.: Comp. Biochem. Phys. C, 105, 347 (1993)

Applications Desacetyllanatoside C is a derivative of Lanatoside C (L173800), glycosides isolated from various species of Digitalis. Cardiotonic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Novotny, J., et al.: J. Biol. Chem., 258, 14433 (1983), Farr, C., et al.: J. Med. Chem., 45, 3257 (2002), Van Dongen, M., et al.: Drug Discov. Today, 7, 471 (2002),

Applications Dimension can be employed as a herbicide.
References Zhang, R., et al.: Sepu., 36, 1228-1237 (2018)

Applications Fluticasone Propionate-d5 is the labeled analogue of Fluticasone Propionate (F599500), a derivative of Flumethasone. An antiallergic; anti-asthmatic; anti-inflammatory.
References Meltzer, E.O., et al.: J. Allergy Clin. Immunol., 86, 221 (1990); Mitchison, H.C., et al.: Gut, 32, 260 (1991); Phillipps, G.H., et al.: J. Med. Chem., 37, 3717 (1994)

Applications (-)-Donepezil is an isomer of Donepezil (D531750), a nootropic, acting as an inhibitor of acetylcholinesterase.
References Ohnishi, A., et al.: J. Clin. Pharmacol., 33, 1086 (1993), Galli, A., et al.: Eur. J. Pharmacol., 270, 189 (1994)

Stability Moisture Sensitive
Applications Trans-1,2-cyclohexanedicarboxylic anhydride can be used as a reagent to prepare hepatitis C virus (HCV) and granzyme B (indoline derivatives) inhibitors. It has also been employed in studies relating to the development of protein kinase C inhibitors.
References Yang, Z., et al.: PCT Int. Appl. WO 2015124063 A1 20150827 (2015); Cameron, D. R. PCT Int. Appl. WO 2014153666 A1 20141002 (2014); Cameron, D. R. PCT Int. Appl. WO 2014153666 A1 20141002 (2014); Lampe, J. W., et al.: J. Med. Chem 45, 2624

Applications Bromadiolone is an anticoagulant rodenticide used on non-crop areas.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Cherry, L., et al.: Toxicologist, 2, 108 (1992), Park, B., et al.: Biochem. Pharmacol., 31, 3635 (1992), Thijssen, H., et al.: Pestic Sci., 43, 73 (1995), Howald, G., et al.: Conserv. Biol., 21, 1258 (2007),

Applications Mesosulfuron is used in synergistic herbicidal combinations.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Baur, P., et al.: PCT Int. Appl. (2020), WO 2020173719 A1

Stability Hygroscopic, Unstable in Solution
Applications Amoxycilloic Acid Sodium Salt is an impurity of Amoxicillin (A634235), a semi-synthetic antibiotic related to Penicillin. Antibacterial.
References Connor, S., et al.: J. Pharm. Pharmacol., 46, 128 (1994); Van G., et al.: J. Vet. Pharmacol. Ther., 26, 139 (2003); Brogden, R.N., et al.: Drugs, 18, 169 (1979); Bird, A.E., et al.: Anal. Profiles Drug Subs. Excip., 23, 1 (1994)