Toxicologie

Applications Lufenuron is a benzoylurea pesticide which inhibits the production of chitin in larval fleas.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Dryden, M.W.,et al.: Int. J. App. Res. Veterrin. Med., 10, 198 (2012); Malhat, F., et al.: Bull. Environ. Contamin. Toxicol., 89, 1037 (2012);

Impurity Mometasone Furoate EP Impurity D
Applications A21-Chloro-17α-[(2-furanylcarbonxyl)oxy]-9β,11β-oxido-16α-methylpregna-1,4-diene-3,20-dione (Mometasone EP Impurity D) is a impurity of Mometasone Furoate.
References Shapiro, E.L., et al.: J. Med. Chem., 30, 1581 (1987), Graft, D., et al.: J. Allergy Clin. Immunol., 98, 724 (1996)

Applications Olivetol-d9 is a precursor in various syntheses of labelled tetrahydrocannabinols.
References Kumano, T., et al.: Bioorg. Med. Chem., 16, 8117 (2008), Appendino, G., et al.: J. Nat. Prod., 71, 1427 (2008), Sampietro, D., et al.: Food Chem., 115, 1170 (2009),

Applications (1S,2R)-2-((Benzyloxy)methyl)cyclopent-3-enol is an intermediate in the synthesis of Entecavir (E558900), an oral antiviral drug used in the treatment of hepatitis B infection.
References Gathergood, N., et al.: J. Org. Chem., 66, 1014 (2001);

Applications Nandrolone-13C2 Benzoate is the isotope analog of Nandrolone Benzoate. Nandrolone Benzoate is a steroid that has effect on gondatropin and muscles, which is derived from Nandrolone (an anabolic steroid).
References Lerner, L.J., et al.: Endocrinology, 64, 1010 (1959); Gradeen, C., et al.: J. Anal. Toxicol., 14, 120 (1990); Teale, P., et al.: Biol. Mass Spectrom., 20, 109 (1991); Yamada, M., et al.: J. Pharm. Biomed. Anal., 45, 125 (2007); Yamada, M., et al.: J. Anal. Toxicol., 32, 387 (2008)

Applications Fluorinated quinolone antibacterial. An enantiomer of Levofloxacin (L360000).
References Hwangbo, H.J. et al.: Eur. J. Pharmac. Sci., 18, 197 (203); Gascon, A.R. et al.: J. Clin. Pharmacol, 40, 869 (2000); Monk, J.P., et al.: Drugs, 33, 346 (1987); Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990);

Applications An active metabolite of Glimepiride.
References Muller, G., et al.: Diabetes, 42, 1852 (1993), Kramer, W., et al.: Biochem. Biophys. Acta, 119, 278 (1994),

Applications It is a bisbiguanide with bacteriostatic activity. Antiseptic; disinfectant.
References Davies, G.E., et al.: Br. J. Pharmacol., 9, 192 (1954), Foulkes, D.M., et al.: J. Periodontal Res., 8, 55 (1973),

Applications Isotope labelled Diethyl Oxalate is used in the synthesis of novel indole β-diketo acid derivatives as HIV-1 integrase inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sechi, M., et al.: J. Med. Chem., 47, 5298 (2004);

Applications A deuterated prodrug of Penciclovir (P221500), which is used as an antiviral.
References Hodge, V.R.A., et al.: Antimicrob. Ag. Chemother., 33, 1765 (1989),

Stability Light Sensitive
Applications An impurity of Minocycline (M344800). Used in the preparation of calpain inhibitors.
References Sokoloski, T.D., et al.: J. Pharm. Sci., 66, 1159 (1977), Naidong, W., et al.: J. Pharm. Biomed. Anal., 13, 905 (1995),

Applications Sulfacetamide-d4 is the isotope labelled analog of Sulfacetamide. Sulfacetamide is an antibiotic used for the treatment of skin infections and urinary tract infections. Sulfacetamide is also used to treat acne and seborrheic dermatitis. Sulfacetamide was investigated for potential anti-inflammatory properties
References Wittwer, M.B., et al.: J. Med. Chem., 56, 781 (2013); Wang. X., et al.: Afr. J. Micriobiol., 6, 4533 (2012); Yu, B., et al.: Euro. J. Med. Chem., 46, 5833 (2011);

Applications Intermediate in the production of Oseltamivir. It is a COVID19-related research product.
References Kim, C., et al.: J. Med. Chem., 41, 2451 (1998), Carbain, B., et al.: Chem. Med. Chem., 4, 335 (2009),

Applications Isotope labelled Vinclozolin (V314050), which is an agricultural fungicide which acts through an anti-androgenic mode of action, however is incapable of disrupting endocrine homeostasis (1). Affects male reproductive organs through increased gonad activity with spermatogenesis with deformities (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Flick, B. et al.: Arch. Toxicol. 2017 Apr;91(4):1941-1956.2. Watermann, B. et al.: J. Environ. Sci Health A Tox Hazard Subst Environ Eng. 2016 Nov 9;51(13):1111-20.

Applications Huanbifucaotong is used in herbicidal compositions for controlling weeds and other harmful plants.
References Zhao, N., et al.: Pest Manag. Sci., 75, 3175 (2019); Bayer A.-G., et al.: From Eur. Pat. Appl. (2020), EP 3639665 A1 20200422;

Stability Hygroscopic
Applications Mepiquat Chloride is a plant growth regulator used to improve crop quality and maximize yield.
References Xiaoming, R., et al.: Field Crops Res, 149, 1-10 (2013)

Applications A labelled derivative of Vincamine with vasodilating activity. Vasodilator (cerebral).
References Han, et al.: J. Biol. Chem., 274, 22337 (1999), O’Donnell, et al.: Pharmacol. Biochem. Behav., 63, 185 (1999),

Stability Hygroscopic
Applications A metabolite of Valproic acid.
References Rudy, A., et al.: J. Pharmacol. Exp. Ther., 259, 1133 (1991), Nagai, K., et al.: J. Antimicrob. Chemother., 39, 295 (1997), Yamamura, N., et al.: Drug Metab. Dispos., 27, 724 (1999)

Applications (±)-Cyhalothric acid (CAS# 68127-59-3) is a useful research chemical compound.

Applications Isotope labelled Coumachlor (C745000) an internal standard in the analysis of the rodenticide Warfarin.
References Dikshith, T., et al.: J. Exp. Biol., 29, 149 (1991),

Applications Naloxegol Oxalate is an oxalate form of Naloxegol (N284470) which is a peripherally-selective opioid antagonist.
References Seifert, R., et al.: G Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive Activity, 227 (2012)

Applications Avibactam (NXL104) is a novel β-lactamase inhibitor with a non-lactam structural scaffold. NXL104 irreversibly inhibits lactamase from Mycobacterium tuberculosis.
References Iland, C., et al.: J. Pathol. Bacteriol., 58, 495 (1946), Flores, A., et al.: Microbiology, 151, 521 (2005), Livermore, D., et al.: J. Antimicrob. Chemother., 62, 1053 (2008), Tremblay, L., et al.: Biochemistry, 49, 9685 (2010),

Applications Dimoxystrobin is a pesticide component used for its antifungal activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hvezdova, M. et al.: Sci. Total. Env., 613-614, 361 (2018);

Applications Berberine Sulfate is an isoquinoline alkaloid with chemopreventative properties. It is used in the preparation of derivatives showing activity against leishmaniasis and malaria.
References Bahar, M. et al.: Bioorg. Med. Chem. Lett., 21, 2606 (2011); Endeshaw, M. et al.: J. Nat. Prod., 76, 311 (2013);

Stability Hygroscopic
Applications Dihydro Caffeic Acid 3-O-β-D-Glucuronide is a glucuronide metabolite of Caffeic Acid (C080000).
References Clifford, M., et al.: J .Agric. Food Chem., 53, 3821 (2005), Lafay, S., et al.: J. Nutr., 136, 1192 (2006), Poquet, L., et al.: Drug Metab. Dispos., 36, 190 (2008)

Applications Creatine-(methyl-d3) Monohydrate is an isotopic analog of Creatine Monohydrate (6020-87-7), which is a nitrogenous organic acid that occurs naturally in vertebrates. Its main role is to facilitate recycling of Adenosine Triphosphate (ATP), the energy currency of the cell, primarily in muscle and brain tissue.
References Barcelos, R.P., et al.: Mini Rev Med Chem., 16, 12-8 (2016)

Applications Tiropramide is an antispasmodic agent. Studies suggest that Tiropramide has a pure musculotropic smooth muscle relaxant activity. Tiropramide is considered to be useful to inhibit the contractile response of the urinary bladder.
References Myung, S.-W. et al.: J. Appl. Pharmacol., 8, 262 (2000); Kwon, O.-S. et al.: Arzneim.-Forsch., 53, 578 (2003); Jhee, O.H. et al.: Clin. Chim. Acta, 366, 179 (2006); Takayanagi, I. et al.: Gen, Pharmacol., 20, 335 (1989);

Impurity Cefotaxime Sodium EP Impurity A
Stability Hygroscopic
Applications Cefetamet is a third-generation cephalosporin antibiotic and the active agent of Cefeamet pivoxil (C242780) after hydrolysis.
References Bryson, H.M., et al.: Drugs., 45, 589 (1993); Sharma, R.K., et al.: Asian. J. Biochem. Pharmaceut. Res., 1, 443 (2011); Waters, N.J., et al.: Drug. Metabolism. Disposit., 38, 1159 (2010);

Applications Isotope labelled Triclosan is used as bactericide and preservative for cosmetic and detergent compositions (1). Broadly used as an antiseptic and disinfectant (2). This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Lindström, A. et al.: Environ. Sci. Technol. 2002 Jun 1;36(11):2322-9. 2. Ruszkiewicz, J. et al.: J. Toxicol. Environ. Health B. Crit. Rev. 2017;20(2):104-117.

Applications A metabolite of Testosterone (T155000) in human. Controlled substance.
References Seckl, J., et al.: Steroids, 62, 89 (1997), Reynolds, R., et al.: J. Clin. Endocrinol. Metab., 86, 245 (2001), Wolf, C., et al.: Toxicol. Sci. 65, 71 (2002), Borlak, J., et al.: Drug Metab. Dispos., 32, 675 (2004),

Applications 2,4,6-Trichlorophen-3,5-d2-ol is an impurity in the synthesis of isotope labelled Triclosan which is used as bactericide and preservative for cosmetic and detergent compositions (1). Broadly used as an antiseptic and disinfectant (2). This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.

Stability Hygroscopic
Applications Fosetyl Aluminum-d15 is a deuterated version of Fosetyl Aluminum (F727450), a fungicide. Fosetyl Aluminum has a potent inhibitory activity against several species of Phytophthora.
References Fenn, M., et al.: Phytopathology, 74, 606 (1984); Matheron, M., et al.: Plant Disease, 84, 454 (2000)

Applications Metaldehyde
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Labelled Bilirubin (B385300), a principal pigment of bile and constituent of many biliary calculi.
References Stenhagen, R., et al.: Biochem. J., 33, 1591 (1939), Gray, et al.: J. Chem. Soc., 2264, 2268 (1961),

Applications Nucleoside analog; specific inhibitor of hepatitis B virus (HBV) replication. Antiviral.
References Standring, D.N., et al.: Antiviral. Chem. Chemother., 12, 119 (2001), Hernandez-Santiago, B., et al.: Antimicrob. Agents Chemother., 46, 1728 (2002), Lai, C.-L., et al.: Hepatology, 40, 719 (2004), Han, S.-H.B., et al.: Expert Opin. Invest. Drugs, 14, 511 (2005),

Applications T-705RTP-13C5 Sodium Salt is a labeled salt derivative of T-705 (F103350) which has activity against the lethal H5N1 influenza A viruses.
References Yousuke, F., et al.: Antimicrob Agent Chemother., 49, 981 (2005); Kiso, M., et al.: Proc. Natl. Acad. Sci. U.S.A., 107, 882 (2010)

Stability Material darkens in storage with no loss in purity
Applications 3-Chlorobenzenamine is used in the synthesis of pyrimidoazepine analogs as serotonin 5-HT2A and 5-HT2C receptor ligands for the treatment of obesity. Also used in the synthesis of novel COX-2 inhibitors.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yang, H. et al.: Eur. J. Med. Chem., 63, 558 (2013); Penning, T. et al.: J. Med. Chem., 40, 1347 (1997);

Applications 8-Epitacrolimus is a new l-pipecolic acid macrolide lactone, an important immunosuppressive drug that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. 8-Epitacrolimus is also an Epimer of Tacrolimus (F370000).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Skytte, D.M., et al.: J. Nat. Prod.,73, 776 (2010); Rokaw, M.D., et al.: Am. J. Physiol., 271, C194 (1996); Knoll, G.A., and Bell, R.C.: Brit. Med. J., 318, 1104 (1999);

Applications The main cis-monohydroxylated metabolite of Praziquantel (P702095).
References Buehring, K., et al.: Eur. J. Drug Metab. Pharm., 3, 179 (1978), Moldeus, P., et al.: Methods Enzymol., 52, 60 (1978), Cioli, D., et al.: Pharmacol. Ther., 68, 35 (1995),

Applications A labelled metabolite of Cortisol (H714615).
References Aguilera, R., et al.: Clin. Chem., 47, 292 (2001), Pujos, E., et al.: Anal. Bioanal. Chem., 381, 244 (2005), Flenker, U., et al.: Steroids, 73, 408 (2008),

Applications Trimethoprim lactate salt is an antibacterial agent.
References Lees, G. et al.: Brit. J. Pharmacol., 73, 535 (1981);

Applications Labelled analogue of Sulfachlorpyridazine, an antibacterial compound.
References Wammer, K.: Environ. Toxicol. Chem. 25, 1480 (2006);

Applications Used as an antiseptic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gaines, T.B. and Linder, R.E.: Fundam. Appl. Toxicol., 7, 299 (1986)

Applications Thallium sulfate is an inorganic compound used in the preparation of luminescent extended one-​dimensional heterobimetallic chain compounds with relativistic metal-​metal bonds, by reaction with gold thiophosphinomethyl complexes.
References Wang, S.; et al.: Inorg. Chem., 28, 4623 (1989);

Applications Chloramphenicol-d5, is the labeled analogue of Chloramphenicol (C325030), which has a broad spectrum of activity against Gram-positive and gram-negative bacteria. It is also antibacterial, and antirickettsial.
References Bartz, et al.: J. Biol. Chem., et al.: 172, 445 (1948), Gottlieb, et al.: J. Bacteriol., 55, 409 (1948), Szulczewski, D., et al.: Anal. Profiles Drug Subs., 4, 47 (1975), Price, A., et al.: J. Antibiot., 43, 118 (1981), Shalit, I., et al.: Drugs, 28, 281 (1984),

Applications Diafenthiuron is an insecticide.
References Delbeke, F., et al.: Entomophaga, 42, 349 (1997); Mezcua, M., et al.: Anal. Chem., 81, 913 (2009);

Applications N-Methylol Minocycline is a derivative of Minocycline Hydrochloride (M344800); a second generation tetracycline antibiotic. Antibacterial.
References Zbinovsky, V., et al.: Anal. Profiles Drug Subs., 6, 323 (1977); Oringer, R.J., et al.: J. Periodontol., 73, 835 (2002); Chung, J.Y.L., et al.: Tetrahedron Lett., 49, 6095 (2008)

Stability Hygroscopic
Applications Metam-sodium-d3 Hydrate is labelled Metam-sodium (M225810,Hydrate; M258950, anhydrous) which is a soil fumigant that is widely used as a pesticide.
References Reif, D.M., et al.: Enviro. Health. Perspect., 118, 1714 (2010); Knight. A.W., et al.: Regulat. Toxicol. Pharmacol., 55, 188 (2009);

Stability Hygroscopic
Applications Cefotaxime is an antibiotic with broad spectrum activity against Gram positive and Gram negative bacteria.

Applications L-Hercynine-d3 is the isotope labelled analog of Hercynine (H288900); a precursor of L-(+)-Ergothioneine (E600000) which is a natural molecule isolated from the rye ergot fungus and later identified in rat erythrocytes and liver and in numerous other animal tissues. Its antioxidizing properties may afford the compound therapeutic potential or it may be used as a food additive or in cosmetics.
References Genghof, D.S., et al.: J. Bacteriol., 95, 340 (1968); Nakamura, T., et al.: Biol. Pharm. Bull., 31, 1580 (2008); Yang, J., et al.: Food Chem., 114, 898 (2009); Grigat, S., et al.: Drug Metab. Disposition, 37, 330 (2009);

Stability Light Sensitive
Applications 7H-Benzo[c]fluorene is a polycyclic aomatic hydrocarbon (PAH) with mutagenic activity. 7H-Benzo[c]fluorene is a major DNA adduct-forming component of coal tar. Recent studies suggest that 7H-Benzo[c]fluorene may be capable of inducing lung tumors.
References Lavoie, E.L. et al.: Mutat. Res. Lett., 91, 167 (1981); Koganti, A. et al.: Carcinogenesis, 21, 1601 (2000); Weyand, E.H. et al.: Polycyc. Arom. Comp., 24, 1 (2004);

Applications 2-Methyl-4-isothiazolin-3-one Hydrochloride is an isothiazolinone based biocide and preservative used in personal care products. It is also implicated as an allergen. 2-Methyl-4-isothiazolin-3-one is also used for controlling microbial growth in water-containing solution.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Collier, P.J., et al.: J. App. Bacteriol., 69, 578 (1990); Smaoui, S., et al.: Biocontrol. Sci., 17, 135 (2012); Lodders, N., et al.: System. App. Microbiol., 35, 246 (2012); Felix, J.S., et al.: Anal. Bioanal. Chem., 403, 2869 (2012); Chem. and Eng. News, p.22 Dec. 15, 2014

Impurity Entecavir EP Impurity A
Applications An epimeric impurity of the antiviral drug Entecavir (E558900).

Applications Imatinib-d8 is a deuterated tyrosine kinase inhibitor. It is a COVID19-related research product.
References Schindler, T., et al.: Science, 289, 1938 (2000); Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001)

Applications Imidaclothiz is an action body of nicotinic acid acetylcholinesterase enzyme acceptor. It can be used as a pesticide. After pests contact the product, the normal conduction of their central nerves is inhibited and pests are numbed to death.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jeschke, P., et al: PCT Int. Appl. (2009), WO 2009135613 A1 20091112; Kagabu, S., et al.: J. Agricultural Food Chem., 55, 812 (2007); Wang, Y., et al.: Pest Management Sci., 68, 1564 (2012)

Stability Light Sensitive
Applications Germacrone is an antiviral isolate of Geranium macrorrhizum which inhibits and prevents early stage influenza virus infection. It also inhibits the proliferation of glioma cells by promoting apoptosis.
References Liao, Q. et al.: Antiviral. Res., 100, 578 (2013); Liu, B. et al.: Mol. Med. Reports., 10, 1046 (2014);

Applications Monosulfuron Ester is herbicidal compound containing Monosulfuron-Ester and Nicosulfuron.
References Ge, J., et al.: Faming Zhuanli Shenqing, (2018);

Applications Labelled Albendazole (A511610). An anthelmintic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhao, Y., et al.: Org. Biomol. Chem., 6, 4509 (2008), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),

Applications 4-Chlorobenzenesulfonic acid is an aromatic compound that is used to synthesize a variety of sulfonyl azides. 4-Chlorobenzenesulfonic acid is also used for its effectivenes in promoting para-selective reactions.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bovonsombat, P., et al.: Tetrahedron, 66, 6928 (2010); Kiani, A., et al.: J. Sulf. Chem., 35, 119 (2014)

Impurity USP Cefdinir Related Compound A Sodium Salt
Stability Hygroscopic
Applications (2(R)-2-[(Z)-2-(2-Aminothiazol-4-yl)-2-(hydroxyimino)acetamido]-2-[(2RS,5RS)-5-methyl-7-oxo-2,4,5,7-tetrahydro-1H-furo[3,4-d][1,3]thiazin-2-yl]acetic Acid is an impurity in the synthesis of Cefdinir (C242670), a Cephalosporin antibiotic structurally similar to Cefixime (C242800).
References Kamimura, T., et al.: Antimicrob. Agents Chemother., 25, 98 (1984),Yamanaka, H., et al.: J. Antibiot., 38, 1738 (1985), Guay, D.R.P., et al.: Antimicrob. Agents Chemother., 30, 485 (1986),

Applications Glecaprevir is an antiviral drug used in the treatment of patients with hepatitis C virus (HCV) genotype 1-6, of special interest for the treatment of patients with chronic kidney disease also suffering from HCV.
References Kwo, P., et. al.: J. Hepatol, 67, 263 (2017)Gane, E., et. al.: N. Engl. J. Med, 377, 1448 (2017)

Applications Antioxidant in feed and food; antidegradation agent for rubber.
References Wilson, R.H., et al.: Agric. Food Chem., 7, 206 (1959), Skaare, J.U., et al.: Xenobiotica, 9, 649 (1979), Prochaska, H., et al.: Cancer Res., 48, 4776 (1988), Bammler, T., et al.: Toxicol. Sci., 54, 30 (2000), Hayes, J., et al.: Cancer, 174, 103 (2001),

Applications Linezolid N-oxide is a derivative of Linezolid (L466500), an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant (such as Vancomycin [HCl: V096500] resistant enterococci). Linezolid works by inhibiting bacterial protein synthesis.
References Dennis, L., et al.: Clin. Infect. Dis., 34, 1481 (2002); Clemett, D. & Markham, A.: Drugs, 59, 815 (2000); Gonzales, R., et al.: Lancet, 357, 1179 (2001); Tsiodras, S., et al.: Lancet, 358, 207 (2001)

Applications An analog of labelled Sildenafil; a novel pyrazolopyrimidinethiones as PDE5 inhibitor.
References DeBono, R., et al.: Pharm. Technol., 26, 72 (2002), Blok-Tip, L., et al.: Food Addit. Contam., 21, 737 (2004), Liang, Q., et al.: J. Pharm. Biomed. Anal., 40, 305 (2006),

Applications Cyprodinil is a broad-spectrum fungicide of the class of pyrimidinamines. It is commonly used for protection of cereal crops and fruits against fungal infections. Useful in cannabis testing kits as a component of pesticide mixes (P698235).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Heye, U.J. et al.: Bright. Crop Prot. Conf., Pests Dis., 2, 501 (1994); Boric, B. et al.: Pesticidi, 12, 277 (1997); Knauf-Beiter, G. et al.: Plant Dis., 79, 1098 (1995);

Applications Tricyclic antidepressant; inhibits the serotonin and norepinephrine transporters. Has little effect on the dopamine transporter.
References Wood, M.D., et al.: Neuropharmacology, 26, 1081 (1987), Casis, O., et al.: J. Cardiovasc. Pharmacol., 32, 521 (1998), Linner, L., et al.: Biol. Psychiatry, 46, 766 (1999), Teschemacher, et al.: Br. J. Pharmacol., 128, 479 (1999),

Applications Atazanavir is a novel azapeptide HIV protease inhibitor (PI). Antiviral. Like other antiretrovirals, it is used to treat infection of human immunodeficiency virus (HIV). Newer research has been investigating the potential anticancer effects of atazanavir
References Palella, F.J. Jr., et al.: N. Engl. J. Med., 338(13), 853 (1998), Nolan, D., et al.: Drugs, 63(23), 2555 (2003), Musial, B.L., et al.: Am. J. Health Syst. Pharm., 61, 1365 (2004), Wood, R., et al.: J. Acquir. Immune Defic. Syndr., 36, 684 (2004),

Applications Prometon is a major soil sterilant agent, used as an herbicide for weeds both annual and perennial. This compound is a contaminant of emerging concern (CECs).
References Fernandez-Ramos, C. et al.: Sci. Total Env., 497, 459 (2014); Dodson, R. et al.: Env. Sci. Tech., 49, 113 (2015);

Applications Alodane (cas# 2550-75-6) is a compound useful in organic synthesis.

Applications Triclosan O-β-D-Glucuronide is a metabolite of the bacteriostat, Triclosan (T774250).
References Moss, T. et al.: Food Chem. Toxicol., 38, 361 (2000); Wu, J. et al.: Sepu, 27, 724 (2009);

Applications Vasodilator (coronary).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hay, D., et al.: Br. J. Pharmacol., 76, 103 (1982), Tanaka, T., et al.: Biochemistry, 24, 5281 (1985), Rampe, D., et al.: Pharmacol. Exp. Ther., 265, 1125 (1993),

Applications Fenazaquin is a non-systemic acaricide/insecticide used widely in controlling mites and other related pests in fruits, vegetables and tea.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kumar, V.,et al.: Food. Chem. Toxicol., 44, 596 (2006); Duhan, A., et al.: Bull. Environ. Contamin. Toxicol., 87, 180 (2011);

Applications 4-Methyl-2-pentanol is used in the synthesis of 4-quinolone derivatives as high-affinity ligands for the brain GABAA receptors. Also used in the preparation of antimycotic imadazoles, as antifungals.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lager, E. et al.: J. Med. Chem., 49, 2526 (2006); Heeres, J. et al.: J. Med. Chem., 22, 1003 (1979);

Applications Isotope labelled Molinate (M486477), which is a herbicide that is used to control broad-leaved and grassy plants in rice and other crops (1,2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Nacher-Mestre, J. et al.: J. Agri. Food. Chem. 2014 Mar 12;62(10):2165-742. Sugrue, E. et al.: Appl. Environ. Microbiol. 2015 Apr;81(7):2612-24.

Applications Isotope labelled o-Cresol is a compound used as a disinfectant and have also been used as antiseptic in surgery.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Razavi, S.M., et al.: Nat. Prod. Res., 26, 2148 (2012); Asadollahi-B. M., et al.: Environ. Toxicol. Pharmacol., 34, 826 (2012);

Applications Desethyldesisopropyl Atrazine is a metabolite of Atrazine (A794600).
References Adams, N., et al.: J. Agric. Food Chem., 38, 1411 (1990), Abbas, R., et al.: Toxicol. Appl. Pharmacol., 147, 15, (1997), Cooper, R., et al.: Toxicol. Sci., 2000, 53, 297 (2000), Hossain, M., et al.: Toxicology, 248, 52 (2008),

Applications cis-Tetrahydrophthalimide is an intermediate to synthesize cis-Captafol (C175740), which was used as a fungicide.
References Knight, A., et al.: Regulatory Toxicol. Pharmacol., 55, 188 (2009); Rotroff, D., et al.: J. Toxicol. Environ. Health Part B Critical Rev., 13, 329 (2010)

Applications Used as an anticholelithogenic. Epimer with Chenodiol with respect to the hydroxyl group at C7.
References Tint, G.S., et al.: Gastroenterology, 91, 1007 (1986), Poupon, R.E, et al.: N. Engl. J. Med., 324, 1548 (1991), MacKenzie, P., et al.: J. Biol. Chem., 283, 36205 (2008),