Toxicologie

<p>Applications Systemic post-emergence herbicide for use in food crops and mesquite.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pik, A.J., J. Agric. Food Chem., 25, 1054 (1977), Bovey, R.W., et al.: Weed. Sci., 33, 349 (1985),<br></p>

<p>Applications Coproporphyrin I Dihydrochloride is a porphyrin biomarker with an absorption of λmax 395 nm.<br></p>

<p>Applications Bromoxynil is a nitrile herbicide. Bromoxynil is effective in post-emergent control of broad leaf weeds in cereal, corn, sorghum, onions, flax, mint, turf, and on non-cropland.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bhattacharya, S.P. et al.: Pesticides, 22, 7 (1988); Culpepper, A.S. et al.: Weed Technol., 12, 554 (1998); Rosales-Robles, E. et al.: Weed Technol., 19, 385 (2005);<br></p>

<p>Applications Fenoxaprop-P is an agro-product, used in pesticide formulations.<br>References Han, Y. et al. et al.: J. Sep. Sci., 40, 878 (2017);<br></p>

<p>Applications Isotope labelled Acetamide (A133060) which is often used as plasticizer and as industrial solvent (1). It can also be used for the transamidation of carboxamides in 1,4-dioxane in the absence of a catalyst (2) . Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Ma, X. et al.: Carb. Polym. 2004 Aug:57(2):197-2032. Vanjari, R. et al.: Tetrahedron. Lett. 2013 MayL54(20):2553-5<br></p>

<p>Applications Acrivastine is an allergy medication that is histamine H2 antagonists.<br>References Manna, V.K., et al.: J. Int. Med. Res., 20, 106 (1992);<br></p>

<p>Stability Hygroscopic<br>Applications A metabolite of Carnitine.<br>References Huang, Z., et al.: Anal. Biochem., 199, 98 (1991), Friolet, R., et al.: J. Clin. Invest., 94, 1490 (1994), Rashed, M., et al.: Pediatr. Res., 38, 324 (1995), Costa, C., et al.: J. Lipid Res., 38, 173 (1997),<br></p>

<p>Applications A labelled selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in the treatment of familial adenomatous polyposis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>

<p>Stability Hygroscopic<br>Applications An alpha agonist, causing constriction of conjunctival blood vessels. Used in over-the-counter eye drops, this compound relieves the redness left by ocular irritants.<br>References Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005), Sandri, G., et al.: Eur. J. Pharm. Biopharm., 62, 59 (2006), Rosenthal, R., et al.: J. Ocular Pharmacol. Ther., 22, 440 (2007), Sabio, S., et al.: J. App. Oral Sci., 16, 280 (2008),<br></p>

<p>Applications Antiarrhythmic (class IA). Sodium channel blocker.<br>References Adelstein, et al.: J. Med. Chem., 16, 309 (1973), Czeisler, J.L., et al.: J. Pharm. Sci., 74, 750 (1985), Taylor, E.H., et al.: Ann. Clin. Lab. Sci., 16, 289 (1986),<br></p>

<p>Applications A metabolite of halopropanes.<br>References Barnsley, E.A.: Biochem. J., 100, 362 (1966)<br></p>

<p>Applications 26-Deoxymonensin A Sodium Salt is a metabolite of Monensin (M515600, Na salt); a polyether antibiotic and coccidiostat.<br>References Pospisil, S., et al.: Appl. Environ. Microb., 60, 1561 (1994); Ashworth, D.M., et al.: J. Antibiot., 42, 1088 (1989);<br></p>

<p>Stability Air Sensitive<br>Applications Methimazole is a thiourea antithyroid agent that prevents iodine organification, thus inhibiting the synthesis of thyroxine. Antihyperthyroid.<br>References Sitar, D.S., et al.: J. Pharmacol. Exp. Ther., 184, 432 (1973), Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 8, 351 (1979), Cooper, D.S., et al.: N. Engl. J. Med., 311, 1353 (1984), Atterwill, C.K., et al.: Food Chem. Toxicol., 29, 355 (1991),<br></p>

<p>Applications Ethoxysulfuron<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Light Sensitive<br>Applications Permethrinic Acid Methyl Ester is an impurity of the insecticide Permethrin (P288500), which is synthetic pyrethroid insecticide with low mammalian toxicity. Permethrinic Acid Methyl Ester is also used as a reactant in preperation of β-ketoesters via sodium hydroxide catalyzed crossed Claisen condensation of ketene silyl acetals and methyl esters.<br>References Elliott, M., et al.: Nature, 246, 169 (1973); Nowell, L., et al.: Sci Total Environ, 476-477, 144 (2014); Iida, A., et al.: Chem Commun (Camb), 25, 3171 (2005)<br></p>

<p>Applications Methyl-1-Testosterone is a derivative of dihydrotestosterone. Methyl-1-Testosterone is a designer anabolic steroid that is on the world anti-doping agency’s (WADA) prohibited list.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Parr, M.K. et al.: Endocrinology, 152, 4718 (2011); Liu, Y. et al.: Drug Test. Anal., 3, 54 (2011); Jeon, B.W. et al.: Anal. Bioanal. Chem., 401, 1353 (2011);<br></p>