Produits biochimiques et réactifs

<p>TES-ADT is a molecule that can be used as a gas sensor. It has optimum concentration, gas sensing properties, and is stable in air. TES-ADT is also processable, has high chemical stability, and can be patterned at low energy. It has a thermal expansion of 1.7 ppm/K and an spontaneous lattice constant of 0.5 nm/A. TES-ADT is an inorganic material with surface properties including silicon (Si) with the formula Si4N2O2R4+H2O. Its density can be adjusted to match the desired morphology and patterning by changing the ratio of R:H+.</p>

<p>4-Hydroxy-α-(((3-(2-methoxyphenyl)-1,1-dimethylpropyl)amino)methyl)benzenemethanol is a synthetic compound classified as a beta-adrenergic agonist. This chemical is derived from laboratory synthesis, involving the modification of phenylethanolamine structures to achieve specific adrenergic properties.</p>

<p>ML095 hydrochloride is a phosphatase inhibitor that has shown anti-tumour activity in vitro and in vivo. It inhibits the enzyme placental alkaline phosphatase (PLAP) by binding to it, thereby preventing the removal of phosphate groups from substrates. This leads to an accumulation of substrate molecules, which may have an effect on cell signalling pathways and biological functions such as cell proliferation and migration. ML095 hydrochloride has been shown to modulate cancer cell growth in vitro and in vivo. This molecule also inhibits the activity of other phosphatases including pancreatic, testicular, and intestinal enzymes.<br>The compound is a potent inhibitor of bladder cancer cell growth in vitro and in vivo, as well as bladder carcinoma cells that express high levels of PLAP. The compound has been shown to be safe for use by children with cancer or those who have undergone surgery for bladder cancer at doses up to 10 mg/kg body weight.</p>

<p>CID-1067700 is a small molecule that is able to inhibit the ubiquitin proteasome system (UPS) and effector proteins. This drug has been shown to be active against wild-type strains of bacteria, such as Mycobacterium tuberculosis. CID-1067700 also inhibits autophagy in mycobacteria, which may be a potential therapeutic target for the treatment of mycobacterial infections. It has been shown to reduce ischemic brain damage in mice and may have therapeutic potential for stroke patients. CID-1067700 binds to the ubiquitin ligase Rsp5 and inhibits its ability to activate transcription factors that regulate cell cycle progression. This inhibition of transcriptional regulation leads to apoptosis, or programmed cell death.</p>

<p>Rocacetrapib is an investigational drug that belongs to the class of cholesteryl ester transfer protein (CETP) inhibitors. It has been shown to have antiviral activity against SARS-CoV and may be useful in the treatment of other viruses, such as HIV and influenza. Rocacetrapib has also been shown to inhibit cell growth and induce apoptosis in human lung cancer cells, which are resistant to cisplatin. This compound also binds to proteinase 3, suggesting a potential use in the treatment of Alzheimer's disease.</p>

<p>sCD40L is a soluble form of CD40, which belongs to the TNF-alpha superfamily. It is an activator of CD40 receptors, which are found on the surface of B cells and other immune cells. The receptor-ligand interaction triggers a series of intracellular signaling events that lead to the proliferation and activation of B cells. sCD40L can be used as a research tool for studying cell biology and protein interactions.</p>

<p>This product is an antiserum targeting amino acids 34-40 of the amyloid beta-protein which is a key component of extracellular plaques found in the brains of patients with Alzheimer’s disease (AD). It may also be involved in the pathogenesis of other neurodegenerative diseases such as Huntington’s disease and Parkinson’s disease. Targeting this protein may be key to drug discovery and the treatment of AD and other diseases this protein is associated with. Furthermore amyloid beta peptides located in the cerebrospinal fluid are well known biomarkers used to diagnose AD. Although AD is not yet curable, an early diagnosis can be useful in that patients can be treated to delay or improve symptoms.</p>

<p>BRD73954 is a potent inhibitor of the HDAC enzyme. It is a molecule that has been shown to inhibit cancer cells, induce pluripotent stem cells and suppress myeloid-derived suppressor cells. BRD73954 contains a carbonyl group, hydroxyl group and fatty acid chain that are essential for its biological activity. The molecule also has a disulfide bond which stabilizes it and helps in the binding to histones. BRD73954 is an all-trans retinoic acid analog that can be used as an adjuvant for vaccines against cancer.</p>

<p>CD38 antibody (PE) was raised in rat using CD38 as the immunogen.</p>

<p>PG01 is a crystalline cellulose that is used in pharmaceutical preparations. PG01 has been shown to inhibit serine proteases, metalloproteases and other enzymes involved in inflammation. This compound was also found to be stable in acidic conditions at high temperatures. PG01 has been shown to inhibit the activity of surface metalloproteases on the surface of cells, which could be used as an anti-inflammatory treatment for chronic inflammatory diseases such as rheumatoid arthritis. The optimum concentration for PG01 to show its effects is 10 μM. It has been shown to have high values against chemical pesticides and can be used as a carrier material for drugs such as insulin.</p>

<p>CD19 antibody (CY5) was raised in rat using murine CD19-expressing K562 human erythroleukemia cells as the immunogen.</p>

<p>Heliotrope B is a film-forming polymer that has been shown to have anticancer properties. It has been used in the treatment of brain tumors, and other cancers such as melanoma and lymphoma, by local administration. Heliotrope B inhibits the growth of cancer cells by binding to their surface membrane receptors. This binding leads to a loss of cell adhesion and prevents tumor cells from attaching to surrounding tissues. Heliotrope B also has antiviral effects against hepatitis viruses, including types A, B, and C. It binds to viral particles and inhibits virus entry into the cell. In addition, heliotrope B can be used in the treatment of HIV infection through its ability to block messenger RNA synthesis by inhibiting reverse transcriptase activity. The polymer is also effective against bacterial strains such as Staphylococcus aureus and Escherichia coli because it disrupts their outer membranes. Heliotrope B has an acidic pH level that makes it</p>

<p>Drotaveraldine is a chromophore, which means it has a fluorescence property. It is used as an excipient in pharmaceutical preparations to improve the appearance of granules and tablets. Drotaveraldine is also used as a pH indicator for citric acid. Drotaveraldine absorbs light at about 350 nm and emits light at about 460 nm when excited with ultraviolet light. The excitation-emission spectrum of drotaveraldine can be used to detect hydrogen chloride, caffeine, or chloride ions in organic solvents. Drotaveraldine is occasionally used for curing biliary calculi in humans, although this use has not been approved by the FDA.</p>

<p>Lamiidoside is a cytotoxic compound found in the ethanol extract of Verbascum thapsus. It has been shown to inhibit the growth of cervical cancer cells, and is a potential treatment for cancer. Lamiidoside is an iridoid glucoside with significant cytotoxicity against tumor cells. It also has antibacterial activity and can be used as a natural food preservative.</p>

<p>HIV-1 TAT Clade-B Recombinant is the recombinant protein that belongs to HIV-1. It is a regulatory protein that binds to the human immunodeficiency virus type 1 (HIV-1) RNA genome and regulates viral replication. HIV-1 TAT Clade-B Recombinant has been shown to be highly infectious and can be used for the study of HIV infection, pathogenesis, and transmission.sequence: MEPVDPRLEP WKHPGSQPKT ACTNCYCKKC CFHCQVCFIT KALGISYGRK KRRQRRRPPQ GSQTHQVSLS KQPTSQSRGD PTGPKE.</p>

<p>Brr2 inhibitor C9 is an antibody that blocks the activation of the Brr2 protein by binding to it. This antibody is a research tool that can be used in cell biology and pharmacology studies, as well as for the study of protein interactions and receptor ligands. The antibody has been shown to increase the amplitude of calcium-dependent currents in cultured rat neurons. It also inhibits voltage-gated potassium channels and enhances GABAergic transmission. This product is high purity, with a purity level of 98%.</p>

<p>CD40 antibody (FITC) was raised in rat using CD40 as the immunogen</p>

<p>LDV is a drug that is used to treat chronic viral hepatitis. It belongs to the class of drugs known as nucleoside analogues and inhibits the replication of the virus by blocking DNA synthesis. LDV has been shown to be effective for treating chronic hepatitis B, chronic hepatitis C, and human immunodeficiency virus (HIV) infection. LDV is metabolized by the liver into its active form, tenofovir. LDV can cause liver impairment and has drug interactions with other drugs. LDV also causes thermal expansion in plastics such as PVC tubing used for dialysis equipment.</p>

<p>CS 2100 is a high-specificity, ethyl-group-containing, blood pressure stabilizer that acts as a serotonin reuptake inhibitor. It has been shown to have efficacy in the treatment of angina and stabilizing cardiac function. CS 2100 has also been used in clinical studies for the treatment of pulmonary embolism, where it was found to reduce the incidence of pulmonary hypertension. CS 2100 binds to serotonin receptors and blocks serotonin reuptake, which enhances its antidepressant effects. CS 2100 also has activity against nt-proBNP (a marker for heart disease) and other markers that are associated with cardiovascular diseases such as sclerosis or coagulation.&gt;&gt;END&gt;&gt;</p>

<p>L-655708 is a benzodiazepine binding inhibitor that binds competitively to the GABA A receptor and blocks the response to GABA. It has been shown to reduce anxiety in mice with a model system of panic disorder. L-655708 has also been shown to have pharmacological activity in mice with brain functions, such as mouse hippocampal, locomotor activity, and receptor binding. L-655708 can be used for treatment of anxiety disorders, such as generalized anxiety disorder (GAD) or panic disorder (PD), and seizures. The drug has a synergistic effect with other drugs that act on GABA receptors, such as benzodiazepines.</p>

<p>MPS is a compound that is used in peptide synthesis. It is a maleimidopropionate reagent that reacts with primary amines to form stable amides. MPS can be used as a building block for the synthesis of polymers, and it contains an N-hydroxysuccinimide ester group that can react with thiols to form stable disulfides. This product is available for purchase from Quanta BioDesign.</p>

<p>Parathyroid Hormone (Human, 69-84) is a peptide hormone that regulates the levels of calcium and phosphate in the blood. It regulates bone formation and remodeling by targeting bone mineralization. Parathyroid hormone binds to to the G-protein coupled receptor type 1 PTH receptor, which activates adenylate cyclase or phospholipase C thus activating pathways involved in the mediation of bone resorption and bone formation. This product is suitable for life science applications and is available has a 0.5mg vial.</p>

<p>Avex-73 is a chemical deterrent, which is derived from naturally occurring plant-based extracts. It operates by affecting the sensory pathways of birds, making treated areas undesirable for them through olfactory and gustatory discomfort. When applied, Avex-73 interacts with the specific chemosensory receptors present in avian species, creating an aversive, yet non-lethal reaction. This makes it an effective tool in managing bird-related challenges in various environments.</p>

<p>CD79b antibody (Azide free) was raised in hamster using the beta chain of the murine B-cell receptor as the immunogen.</p>

<p>CD107b antibody (Allophycocyanin) was raised in rat using glycoproteins purified from BALB/c mouse embryo 3T3 cell line as the immunogen.</p>

<p>CD3e antibody (Spectral Red) was raised in hamster using H-2Kb-specific murine cytotoxic T lymphocyte as the immunogen.</p>

<p>CD107b antibody was raised in mouse using human CD107b/LAMP-2</p>

<p>CD20 antibody (Allophycocyanin-CY7) was raised in mouse using human CD20 as the immunogen.</p>

<p>CD25 antibody (FITC) was raised in rat using IL-2-dependent BALB/c murine helper T-cell clone HT-2 as the immunogen.</p>

<p>CD23 antibody (PE) was raised in rat using CD23 low affinity IgE Fc receptor as the immunogen.</p>

<p>CD45 antibody (Spectral Red) was raised in mouse using chicken CD45 as the immunogen.</p>

<p>CGRP, humanAntiserum is a peptide that is the major peptide in the calcitonin gene-related peptide family. CGRP inhibits the activation of certain ion channels, which are proteins in cell membranes that allow ions to cross the membrane. It is also known to be an activator of certain G protein-coupled receptors, as well as a ligand for some receptor types. CGRP has been shown to play a role in vascular smooth muscle contraction and pain regulation.</p>

<p>Polyvinyl chloride (PVC) is a polymer that is typically used in the production of plastic products. PVC can be made into a variety of shapes and sizes, such as sheets and pipes. The most common type of PVC is polyvinyl chloride with a density range from 0.91 to 0.94 g/cm3. PVC has excellent heat resistance, electrical properties, and chemical resistance, which makes it an ideal material for manufacturing many types of items. Polyvinyl chloride is also resistant to mold or mildew growth.</p>

<p>Mannose binding lectin is a host defense protein which has the ability to recognize a variety of infectious agents. This Mannose Binding Lectin Light Tryptic Peptide Standard can be used in protein identification and quantitation studies.</p>

<p>Brazzien (2-54) is a peptide that binds to the extracellular domain of the human receptor for Advanced Glycation Endproducts (RAGE). This receptor plays an important role in many cellular processes, including tissue damage and inflammation. Brazzien (2-54) is a potent inhibitor of RAGE activity and has been shown to inhibit the binding of RAGE ligands to RAGE.</p>

<p>The HIV-1 p24 Recombinant, His Tag (abbreviated as HIV-1 HRP) is a recombinant protein that is purified from the culture supernatant of transfected HEK293 cells. It has been immobilized on a His-tagged protein A column for purification. The recombinant protein has been proven to be an effective inhibitor of the human immunodeficiency virus type 1 (HIV-1).<br>HRP binds to the CD4 receptor, which is a major component of the cellular membrane. This binding causes conformational changes in the HRP and initiates signal transduction pathways in the cell, leading to an antiviral state.</p>

<p>CD24 antibody (FITC) was raised in rat using murine heat stable antigen as the immunogen.</p>

<p>4-(Benzo[b]thiophen-2-yl)-3-bromo-5-hydroxydihydrofuran-2(3H)-one is a potent inhibitor of Caspase 1. It binds to the active site of the enzyme and prevents it from cleaving its substrate. This chemical is also an activator of Protein Kinase A, which is involved in the regulation of many cellular processes. 4-(Benzo[b]thiophen-2-yl)-3-bromo-5-hydroxydihydrofuran-2(3H)-one is a ligand for Beta1 adrenergic receptors and can be used as a research tool to study protein interactions, receptor activation, and ion channels.</p>

<p>Maltose Binding Protein E.coli Recombinant is a maltose binding protein derived from E. coli that can be used as a research tool in pharmacology and cell biology. Maltose Binding Protein E.coli Recombinant is an antibody that binds to the maltose receptor on the surface of cells, which are found on the outer membrane of most bacteria. Maltose Binding Protein E.coli Recombinant is a high-purity recombinant protein with a molecular weight of about 31 kDa, and has been shown to be an activator and inhibitor of ion channels, depending on its concentration. This protein also interacts with various proteins in the cytoplasm and binds to peptides that have been identified as ligands for this receptor.</p>

<p>Substance P is a member of the tachykinin neuropeptide family which is produced in the central nervous system (CNS) and acts through its specific receptor neurokinin 1 receptor (NK-1R). NK-1R is present in neurons and on glial cell types. Substance P is involved in: pain perceptions as a neurotransmitter; gut motility; increased inflammation in the lungs, gastrointestinal tract and the skin and neuroinflammation. Interestingly the levels of Substance P are raised in inflammatory bowel diseases and through its involvement in cytokine release, it contributes to asthma pathology. These diverse selection of functions makes substance P a target for therapeutic research.</p>

<p>Anti P2X4 (370-388) (Rat) Serum is a research tool that can be used to measure the activation of P2X4 receptors. It is suitable for use in antibody-based applications, such as Western blotting and immunohistochemistry. Anti P2X4 (370-388) (Rat) Serum is a high purity product that has been extensively characterized by NMR spectroscopy, mass spectrometry, and amino acid analysis. The purified peptide is supplied at a concentration of 1 mg/mL in phosphate buffered saline with 0.02% sodium azide as preservative and 50% glycerol as cryoprotectant. The product is sold under reference number CAS No. 74941-79-6 and has the molecular weight of 3199.87 Da. Anti P2X4 (370-388) (Rat) Serum can be used to study protein interactions, receptor ligand pharmacology, ion</p>

<p>H-Arg-Pro-OH sulfate salt is a synthetic peptide that binds to the receptor for filtrates. It is used to treat skin conditions such as dermatitis, eczema, and psoriasis. H-Arg-Pro-OH sulfate salt has been shown to be effective in inhibiting clostridium from producing proteins. This drug also inhibits the uptake of these proteins by blocking the binding of phosphorylated lysine residues to their receptors on the cell membrane. It has been shown to hydrolyze amide bonds and can be used as a catalyst for bond cleavage reactions.</p>

<p>CD4a antibody (PE) was raised in mouse using CD4a as the immunogen.</p>

<p>Gastrokine 2 is a recombinant human peptide that inhibits the activity of an enzyme called protein kinase C (PKC). PKC is involved in a number of cellular processes, including signal transduction and cell proliferation. Gastrokine 2 has been shown to inhibit PKC activity in vitro and in vivo. It has been used as a research tool for studying PKC-mediated signal transduction pathways.</p>

<p>NT 3 Mouse is a peptide that belongs to the group of activators. It is used as a research tool for its ability to activate the protein tyrosine kinase receptor, and is also an antibody. NT 3 Mouse has been shown to be an inhibitor of ion channels and protein interactions. This peptide binds to the receptor and blocks the binding of ligands such as ATP, which are necessary for signaling. The CAS number for NT 3 Mouse is 51101-54-6.</p>

<p>CD24 antibody (biotin) was raised in rat using murine heat stable antigen as the immunogen.</p>

<p>1,6-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-5-C-methoxy-β-L-idopyranose is a potent and selective activator of the Kv1.2 potassium channel. It has been shown to increase the membrane potential in rat sympathetic neurons and to inhibit voltage sensitive sodium channels in rat hippocampal neurons. This compound also activates K+ currents in a concentration dependent manner in human embryonic kidney cells, suggesting that it may have a therapeutic effect on disorders such as epilepsy or Alzheimer's disease.</p>

<p>Ascaroside C3 is a peptide that is derived from the ascaroside family of proteins. Ascarosides are natural products found in the seed coat of the plant Ascaris coarctata. The protein interactions, receptor binding, and ion channel blocking properties of ascarosides have been studied extensively. This peptide has high purity, and is used as a research tool in cell biology and cell-based assays. It can also be used as an antibody or ligand to study protein interactions, receptor binding, and ion channel blocking properties.</p>

<p>CD8a antibody (CY5) was raised in rat using murine thymus or spleen as the immunogen.</p>

<p>Hydroxy-bifenthrin is an analog of bifenthrin, a synthetic pyrethroid insecticide. However, it has been found to have medicinal properties as an anticancer agent. Hydroxy-bifenthrin has been shown to induce apoptosis in cancer cells and inhibit tumor growth. It does this by acting as a kinase inhibitor, disrupting the cell cycle and preventing the production of proteins necessary for cancer cell survival. In addition, hydroxy-bifenthrin has been found in human urine samples, indicating that it may be metabolized in the body and excreted through the kidneys. This promising compound is currently being studied for its potential use in cancer treatment.</p>

<p>CD102 antibody (biotin) was raised in rat using COS cells transfected with mouse ICAM-2 cDNA as the immunogen.</p>

<p>CD103 antibody (PE) was raised in hamster using murine CD103 as the immunogen.</p>

<p>Neuropeptide Y (NPY) is a peptide that regulates appetite, body weight and energy expenditure. NPY(29-64) is used as a research tool for studying the interactions between proteins, antibodies and other ligands. NPY(29-64) also has pharmacological properties such as being an inhibitor of ion channels and a receptor agonist. This peptide is made from high purity materials using recombinant methods.</p>

<p>Rapastinel is a peptide drug for the treatment of major depressive disorder. Rapastinel binds to the NMDA receptor and blocks the binding of glutamate to this receptor, thereby inhibiting its activity. Rapastinel has been shown to be an antagonist at the NMDA receptor and an agonist at the glycine site on the NR1 subunit of this receptor. It also inhibits neurotransmitter release by blocking presynaptic voltage-gated calcium channels and increasing inhibitory GABAergic transmission in the brain.<br>Rapastinel is soluble in water and has a purity of &gt;99% as determined by HPLC analysis.</p>

An apolipoprotein E C-term heavy tryptic peptide standard for use in protein identification and quantitation studies. As part of a fat-binding protein family, apolipoprotein E plays a role in the metabolism of fats in the body through interacting with the low density lipoprotein receptor, which is involved in the catabolism of triglyceride rich lipoproteins. Apolipoprotein E is also a major component in cholesterol metabolism and is a carrier of cholesterol in the brain. Additionally when forming a complex with C1q, apolipoprotein E is an inhibitor of the classical complement pathway. The N and C terminal regions of apolipoprotein are connected by a hinge region and the C-terminal region is a hydrophobic surface made up of three alpha helices and a low density lipoprotein receptor binding site.

<p>Cancer antigen 125 (CA 125) light tryptic peptide standard for proteomics studies. CA 125 is an antigenic tumor marker which can be used to diagnose epithelial ovarian cancers. It is expressed by epithelial ovarian neoplasms and cells lining the fallopian tubes, endometrium, pericardium, peritoneum and pleura.</p>

<p>Anti Met-Enkephalin-Arg6-Gly7-Leu8 Serum is a research tool for the study of ion channels, ligands and receptors. Anti Met-Enkephalin-Arg6-Gly7-Leu8 Serum blocks the binding of peptides to receptors and can be used to determine the specificity of receptor binding. Anti Met-Enkephalin-Arg6-Gly7-Leu8 Serum is also a useful reagent in cell biology, as it can be used to block peptide interactions with proteins such as ion channels or membrane receptors. The antibody has been shown to inhibit the activity of the enzyme tyrosine phosphatase, which regulates cellular growth and differentiation.</p>

<p>Gly-Gly-His is a peptide that binds to copper and forms a complex. It has been shown to have antimicrobial properties in a model system using human serum. Gly-Gly-His is a diazonium salt that reacts with histidine, leading to the formation of an amide bond. The histidine residue can be replaced by other amino acids, such as lysine, arginine, or asparagine. This peptide also has calcium binding properties and has been shown to have biological properties in the femoral vein of rats.</p>

<p>IGF-Like Family Receptor 1 is a recombinant protein that belongs to the receptor family. It is also known as insulin-like growth factor I (IGF-I) receptor, and it has been shown to have ion channel activity. IGF-Like Family Receptor 1 can be used in research and development of pharmacological agents. This recombinant protein will not react with any antibodies or peptides, and it has high purity.</p>

<p>Isoleucyl-Seryl-Bradykinin is a peptide that is derived from the amino acid sequence of bradykinin. It has been shown to exhibit pharmacological properties, such as lowering blood pressure in rats and humans. Isoleucyl-Seryl-Bradykinin has also been found to be an effective treatment for pain relief, particularly in women during estrus.</p>

<p>Putative orf1ab Polyprotein (3233-3247) [SARS Coronavirus] is a high purity, recombinant protein that can be used as a research tool in cell biology, receptor pharmacology and biochemistry. It can also be used as an antibody to detect the presence of SARS coronavirus in cells. Putative orf1ab Polyprotein (3233-3247) [SARS Coronavirus] is an inhibitor of ion channels and ligand for receptor.</p>

<p>Atrial Natriuretic Peptide (ANP) is a hormone that regulates blood pressure and fluid balance. Research has shown that ANP activates the receptor to inhibit the production of cyclic AMP, which is an intracellular second messenger. This process causes the opening of potassium channels, leading to hyperpolarization of the membrane, which decreases the excitability of cells. The ANP Antiserum is used as a research tool for studying the effects of ANP on ion channels and protein interactions in cell biology experiments.</p>

<p>TentaGel B resins represent a line of bifunctional resins that are useful for orthogonal synthesis. TentaGel is a gelatinous resin, an important support for solid phase synthesis. TentaGel resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol). The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix.<br>Particle size 130 µm; capacity: 02-03 meq/g Inside: NH2 Outside: Boc</p>

<p>Suc-Ala-Glu-AMC is a synthetic molecule that is used as a research tool to study protein interactions, ion channels, and other cell biology. Suc-Ala-Glu-AMC binds to specific receptors and activates them. This compound can also be used to isolate ligand/receptor complexes. Suc-Ala-Glu-AMC is a high purity compound with an analytical purity of 98%. It has been shown in pharmacological studies to inhibit the activity of peptides such as vasopressin and oxytocin at the receptor level.</p>

<p>Anti TNF-Alpha (Rat) Serum Host Goat is a research tool that is used to inhibit the production of tumor necrosis factor-α (TNF-α). It is an antibody that binds to TNF-α and prevents it from binding to its receptor. Anti TNF-Alpha (Rat) Serum Host Goat has been shown to inhibit the production of TNF-α in vitro, but not in vivo. This serum can be used as a control for other antibodies that are inhibiting the production of TNF-α.</p>

<p>RLN3 is a peptide that is used as a research tool for the study of ion channels and protein interactions. It has been shown to act as an inhibitor of Kv1.2, which is an ion channel that regulates potassium ions in cells. RLN3 has also been shown to inhibit the binding of the antibody Herceptin to its receptor, which is important for cancer treatment.<br>RLN3 belongs to the class of ligands and receptors, which are proteins found on cells that can bind with other proteins or chemicals in order to regulate cellular activity.</p>

<p>Flurpiridaz F18 is a diagnostic agent that binds to the fatty acid transporter protein in the liver and has been shown to be effective in diagnosing hepatic steatosis. Flurpiridaz F18 is a positron emission tomography (PET) imaging agent that can be used for cardiac, atrial, and ventricular myocardium angiography. It is also a PET imaging agent that can be used for brain function studies. The uptake of Flurpiridaz F18 in the body depends on the body mass index and logistic regression analysis has been used to predict the uptake of this drug from an individual's body mass index.</p>

<p>E6130 is a monoclonal antibody that inhibits the growth of papilloma virus. It binds to an antigen binding molecule and prevents the binding of these molecules to cells that are infected with papilloma virus. E6130 has been shown to be effective in the treatment of bowel disease, including inflammatory bowel disease. The antibody also binds to chemokines, which are potent inflammatory mediators involved in the recruitment and activation of leukocytes. E6130 is used as a diagnostic agent for detecting papilloma virus in blood samples.</p>

<p>CD105 antibody (FITC) was raised in mouse using membrane preparation of human B-lineage leukemia cells as the immunogen.</p>

<p>KS370G is an amide analog of the antibiotic erythromycin. It inhibits efflux pump activity and fatty acid synthesis in Gram-negative bacteria, including Pseudomonas aeruginosa. KS370G also has cardioprotective properties and can be used as a hypoglycemic agent. In rats, it has been shown to reduce the incidence of myocardial infarcts caused by a high-fat diet. In addition, KS370G has antimicrobial activity against P. aeruginosa and other Gram-negative bacteria. This drug is orally bioavailable at doses of 3 mg/kg in Sprague-Dawley rats, with no significant adverse effects observed up to 50 mg/kg.</p>

<p>Neuromedin U Precursor-Related Peptide 33 (Rat, Mouse) is a research tool that can be used to study the effects of neuromedin U on the activation of receptors. This peptide is a ligand for the receptor and has been shown to inhibit ion channels. Neuromedin U Precursor-Related Peptide 33 (Rat, Mouse) may also be used as an antibody or in protein interactions studies. This product is made from high purity materials and can be used in pharmacology and life science experiments.</p>

<p>Adrenomedullin (Human, 1-25) is a vasopressor fragment of the human peptide hormone adrenomedulin. This product has a disulfide bond between Cys16-Cys21 and is available as a 0.5mg vial.</p>

<p>Serum Amyloid A Heavy Tryptic Peptide Standard can be use in protein identification and quantitation studies and level of serum amyloid A are present at a blood concentration of below 3 mg/L in healthy individual. However elevated levels of this protein are found in inflammatory rheumatic diseases, hence making serum amyloid A an excellent biomarker for these types of diseases.</p>

<p>This is a TenetalGel B resin product which represents a line of bifunctional resins that are useful for orthogonal synthesis.<br>TentaGel is a gelatinous resin, an important support for solid phase synthesis. TentaGel resins are constructed with a backbone of low crosslinked polystyrene grafted with polyoxyethylene (polyethylene glycol). The typical chain length of POE (n) is approximately 68 ethylene oxide units or an average MW of 3000. This long chain creates a spacer that effectively separates the reactive site (X) from the crosslinked backbone matrix. <br>Particle size: 90 µm; Boc capacity: 0.2 - 0.3 mmol/g; free NH2 capacity: 4 - 8 µmol/g</p>

<p>CD3e antibody (PE) was raised in mouse using porcine CD3e as the immunogen.</p>

<p>Leptin is a hormone that regulates energy metabolism by modulating appetite and body weight. Leptin is produced by fat cells and signals to the hypothalamus of the brain about how much fat tissue there is. It also helps regulate other metabolic processes, such as insulin resistance and glucose tolerance. Leptin has been shown to have an anorectic effect in rodents, which may be due to its ability to reduce food intake or increase energy expenditure. In humans, leptin levels are higher in obese individuals than in those with normal weight, which indicates that this hormone may play a role in obesity.</p>

<p>Ferritin, human, recombinant, Heavy Chain is a recombinant protein produced by E. coli bacteria. It is a heavy chain of ferritin that is involved in the storage and release of iron in cells. Ferritin is a macromolecule composed of 24 subunits of which each has an iron-binding site. Ferritin acts as an antioxidant and also has been shown to be involved in the regulation of ion channels and ligand binding.</p>

<p>Big Endothelin-2 (Human, 22-38) Antiserum is an antibody that binds to the endothelin receptor and blocks the binding of endothelin. It is a research tool that can be used in cell biology and pharmacology to study the effects of endothelin on ion channels, ligands, and receptor activation. Big Endothelin-2 (Human, 22-38) Antiserum has high purity and is suitable for use in immunohistochemistry or Western blotting techniques. It is also used as an inhibitor for other antibodies, such as anti-endothelin antibody.</p>

<p>Please enquire for more information about Val-His-[D7]Leu-Thr-Pro-Glu including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Glutathione synthetase is an enzyme that catalyzes the synthesis of glutathione from gamma-glutamylcysteine and glycine. It is a homodimeric protein composed of two identical subunits with a molecular weight of about 30 kDa. Each subunit contains one active site for the catalysis. The recombinant human glutathione synthetase has been shown to be stable in different pH buffers and can be used as a research tool or an inhibitor in cell biology experiments.</p>

<p>An inhibitor of β-Glucuronidase</p>

<p>Ac-Lys-Val-Pro-Leu-ACC is a peptide used as a research tool to study protein interactions. Ac-Lys-Val-Pro-Leu-ACC binds to the extracellular domain of the human epidermal growth factor receptor (EGFR) and inhibits EGFR signaling. It blocks ligand binding and receptor activation, which prevents the phosphorylation of downstream signaling proteins. Ac-Lys-Val-Pro-Leu-ACC can be used in pharmacology to identify new drugs that inhibit EGFR signaling pathways.</p>

<p>CD72.1 antibody (PE) was raised in mouse using DBA/2 murine spleen cells as the immunogen.</p>

<p>Anti-Preprorenin (21-64) is a peptide inhibitor of renin. It has been shown to inhibit the activity of renin, an enzyme that plays a key role in regulating blood pressure. Renin cleaves a prohormone called angiotensinogen into angiotensin I, which is then converted to angiotensin II by the angiotensin-converting enzyme. Angiotensin II causes vasoconstriction and stimulates the secretion of aldosterone from the adrenal glands. Anti-Preprorenin (21-64) inhibits renin by binding to its active site and preventing it from converting angiotensinogen to angiotensin I. This product can be used in research as an activator or ligand for receptor or antibody studies.</p>

<p>A soluble transferrin receptor (sTfR) light tryptic peptide standard for protein identification and quantitation studies. sTfR is a cleaved extracellular segments of the transferrin receptor 1 and it can be used to measure the status of iron in the blood and thus help in studies into anemia, where iron is deficient.</p>

<p>The recombinant Borrelia Burgdorferi Outer Surface Protein A (rBOSPA) is a peptide that can be used as a research tool for studying the activation of ion channels and protein interactions. The rBOSPA is an inhibitor of the hKv1.3 channel and has been shown to bind to the GABA receptor. This recombinant protein is purified from E. coli, which makes it suitable for use in experimentation, as it does not contain any potential contaminants or other proteins. The CAS number for this product is</p>

<p>Antiproliferative factor Sialoglycopeptide is a research tool that has been shown to activate the immune system. It has been used as a vaccine carrier and in immunotherapy. Antiproliferative factor Sialoglycopeptide binds to the C-type lectin receptor on erythrocytes, triggering an antibody response. This protein also interacts with ion channels, such as Ca2+ channels, and inhibits protein synthesis by inhibiting the tyrosine kinase activity of protein kinase A (PKA). Antiproliferative factor Sialoglycopeptide is a peptide that is active against many types of cancer cells and has been shown to inhibit tumor growth in mice. The CAS number for Antiproliferative Factor Sialoglycopeptide is 12074-48-2.</p>

<p>1-Naphthalenylsulfonyl-Ile-Trp-aldehyde is a recombinant protein that has protease activity. It is a serine protease that cleaves proteins at the amino acid sequence Ser-Xaa-Gly or Ser-Xaa. The recombinant protein has been shown to have proteolytic activity and can be used in assays to measure the amount of β-catenin, collagen, and growth factor in cells. 1-Naphthalenylsulfonyl-Ile-Trp-aldehyde also binds to monoclonal antibodies and can be used as a neutralizing agent for these proteins. This recombinant protein also has been shown to inhibit the growth of lung fibroblasts.</p>

<p>NO Synthase I (Human, Rat)-EIA Kit (1ea) is a kit that includes antibodies, peptide antisera, and other reagents for the detection of nitric oxide synthase. The kit detects nitric oxide synthase by measuring the nitrite concentration in the sample. Nitric oxide synthases catalyze the conversion of L-arginine to citrulline and nitrite. The assay is used to measure NO production in cell culture or tissue samples.</p>

<p>Anti PACAP27 (13-27) is a research tool that is an activator of the PAC1 receptor, which is a ligand-gated ion channel. It has been shown to have a high affinity for binding to the PAC1 receptor and can be used in cell biology to study protein interactions. Anti PACAP27 (13-27) also inhibits ion channels, such as calcium and potassium channels. Additionally, it has been shown to inhibit the secretion of vasopressin and oxytocin in response to stimuli.</p>

<p>Betamethasone hydrochloride is an inhibitor analog of the protein kinase that has been shown to have anticancer properties. It has been used in Chinese medicine for centuries as a treatment for various diseases, including cancer. Betamethasone hydrochloride acts by inhibiting the activity of kinases, which are enzymes involved in cell signaling pathways that regulate cell growth and division. This drug induces apoptosis, or programmed cell death, in tumor cells by disrupting their normal function. Additionally, betamethasone hydrochloride has been shown to inhibit the growth of cancer cells and reduce tumor size in animal models. It is also used in the treatment of edema associated with kidney disease and tolvaptan-induced hyponatremia by promoting urine production.</p>

<p>Please enquire for more information about Fmoc Gly TentaGel® S RAM resin (particle size: 90 µm capacity: 0.2 - 0.25 mmol/g) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>IL 17A/F Human is a recombinant protein that activates the IL-17 receptor, which is a member of the IL-1 family. It can be used as a research tool in pharmacology and cell biology to study protein interactions. IL 17A/F Human is also an inhibitor of IL-17 and can be used for the treatment of autoimmune diseases.</p>

<p>BD 3 Human is a recombinant cytokine that has been shown to have a spectrum of activity against gram-positive and gram-negative bacteria, as well as yeast. BD 3 Human is produced by recombinant DNA technology and encodes the amino acid sequence of human interleukin-1 beta (IL-1β). It is a member of the IL-1 family, which includes IL-1α, IL-1β, IL-18, and IL-33. The molecular mass of BD 3 Human is 18 kDa. Cytokines are proteins that regulate cellular activities in response to stimuli from other cells or from the extracellular environment. Recombinant cytokines are produced by microorganisms or cells into which recombinant DNA has been introduced. They are used for research purposes, but not for diagnostic purposes or other therapeutic applications. Reconstitute with sterile water for injection before use. Reconstituted solutions may be stored at 2°C to 8°C</p>

<p>6-TAMRA-Amyloid beta-Protein (Human, 1-40) is a fluorescent dye that has been used to study the interaction of amyloid beta protein with ion channels. It can be used in research as a tool to investigate the pharmacology of peptides and proteins. 6-TAMRA-Amyloid beta-Protein (Human, 1-40) is a high purity product that has been shown to inhibit amyloid beta protein binding to receptors.</p>

<p>Follicle stimulating hormone (FSH) is a glycoprotein that is secreted by the anterior pituitary gland. FSH stimulates follicular growth in the ovary and regulates the production of estrogen and progesterone. FSH can be used to treat infertility in women, as well as male hypogonadism. It can also be used for assisted reproduction techniques such as in vitro fertilization, gamete intrafallopian transfer, testicular sperm extraction, and ovarian hyperstimulation. FSH is synthesized from human recombinant DNA and is chromatographically purified with a freeze-dried process. Additives may include antibiotics to prevent bacterial contamination during production or storage. FSH has been shown to act synergistically with estradiol to promote follicular growth in ovaries of immature rats.</p>

Monobiotin is a monovalent cation that inhibits the binding of ATP. It is also a potent activator of the potassium ion channels, and has been used as a research tool for studying the effects of ion channels on cell growth and protein synthesis. Monobiotin has been shown to inhibit the binding of ATP to its receptor, thereby inhibiting protein synthesis in cells. Monobiotin is also an inhibitor of peptidases and can be used as an inhibitor in pharmacology studies. Monobiotin RLN2 is a high-purity monobiotin that does not contain any impurities or other proteins.

<p>Please enquire for more information about Polystyrene AM NH2 (particle size: 250 - 315 µm capacity: 0.8 - 1.2 mmol/g) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Galanin-like peptide (GLP-1) is a human peptide that is a potent activator of the GLP-1 receptor. GLP-1 functions as a ligand for the GLP-1 receptor, which is coupled to G proteins. The activation of this receptor leads to increased calcium influx, which in turn triggers the release of insulin from pancreatic beta cells. GLP-1 also inhibits gastric acid secretion and motility, and functions as an inhibitor of glucagon secretion.<br>GLP-1 has been shown to be a potent inhibitor of ion channels. It binds to Kv3 potassium channels and voltage gated sodium channels, inhibiting their activity by binding to their pore region. In addition, GLP-1 inhibits amyloid beta production by inhibiting protein synthesis in rat brain cells.</p>

<p>Please enquire for more information about ACT 335827 including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>