Produits biochimiques et réactifs

Applications 5-Ethynyl-2’-deoxyuridine is an extensively used nucleoside analog used as a probe for DNA synthesis. 5-Ethynyl-2’-deoxyuridine is known as an toxic anti-metabolite, which potentially causes DNA instabiliy, necrosis and cell-cycle arrest, therefore it is often used for short-term DNA synthesis in tissue culture and living organisms where prolonged cell survival is not required.
References Neef, A.B., et al.: P. Natl. Acad. Sci.., 108, 20404 (2011); Gristwood, T., et al.: Nucleic. Acids. Rsch., 40, 5487 (2012);

Applications Indigo is a chemical compound used as a dye in industrial clothing and textile processes. Also used in the synthesis of organic semiconductors. Dyes and metabolites.
References He, B. et al.: J. Am. Chem. Soc., 136, 15093 (2014); Pitayatanakul, O. et al.: J. mat. Chem. C., Mat. Op. Elec. Dev., 9311 (2014);

Stability Volatile
Applications CIS-BETA-METHYLSTYRENE (cas# 766-90-5) is a useful research chemical.

Applications A metabolite of Cholesterol (C432501).
References Smith, L.L. et al.: J. Am. Chem. Soc., 100, 6206 (1978); Smith, L.L. & Kulig, M.J.: J. Am. Chem. Soc., 98, 1027 (1976); Fieser, L.F. & Stevenson, R.: J. Am. Chem. Soc., 76, 1728 (1954)

Stability Hygroscopic
Applications Labelled Adefovir, which is used as an antiviral.
References Cundy, K.C., et al.: Antimicrob. Ag. Chemother., 39, 2401 (1995), Naesens, L. et al.: Antiviral Chem. Chemother., 8, 1 (1997), Kahn, J., et al.: J. Am. Med. Assoc., 282, 2305 (1999),

Stability Hygroscopic, Light Sensitive
Applications Erythrosine B Disodium Salt is a derivative of fluorone and is used as a cherry-pink synthetic colour additives used on food products. Dyes and metabolites, Environmental Testing
References Xue, H., et al.: Adv. Mat. Res., 476, 2239 (2012); Harp, B. P., et al.: Food. Add. Contamin., 29, 886 (2012); Sarikaya, R., et al.: Chemosphere., 88, 974 (2012);

Stability Hygroscopic
Applications A fatty acid that when in complex acyl-CoA acts as an Acyltransferase enzyme. Found in mice after exposure to endocrine disruptors DEHP and Aroclor 1254.
References Zhang, J. et al.: J. Pharmaceut. Biomed., 66, 287 (2012); Holub, B.J.: BBA-Lipid. Lipid. Met., 664, 221 (1981)

Applications Direct Brown 95, Techincal Grade is an azo dye used in PET/cotton blended fabrics as well as other textiles. Environmental reproductive toxin.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list. Dyes and metabolites, Environmental Testing
References Pielesz, A., et al.: J. Mol. Struct., 511, 337 (1999); Galloway, S., et al.: Env. Mol. Mutagen., 10, 1 (1987)

Applications 2-Methylresorcinol (cas# 608-25-3) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications N-Boc-L-proline is a useful synthetic intermediate. It is used to synthesize Daclatasvir (D101500) which nhibits the HCV protein NS5A. Daclatasvir (D101500) can be used as a drug candidate for the treatment of hepatitis C (HCV).
References Gao, M., et al.: Nature, 465(7294), 96 (2010); Bell, T. W., Chem. Med. Chem., 5(10), 1663 (2010);

Stability Hygroscopic
Applications Glycodeoxycholic acid is a bile acid that induces severe pancreatitis in rats.
References Houghton, A., et al.: Neuroreport, 8, 3795 (1997); Lake, A., et al.: Toxicol. Appl. Pharm., 268, 132 (2013); Zhao, X., et al.: Scand. J. Gastroentero., 37, 1351 (2002)

Applications Leuco Gentian Violet-d6 (Major), is a labelled metabolite of Gentian Violet in seafood products.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rushing, L., et al.: J. Chromatogr., 700, 223 (1997), Ohtsu, H., et al.: J. Med. Chem., 45, 5037 (2002), Yin, D., et al.: Mol. Pharmacol., 63, 211 (2003),

Applications Intermediate in transsulfuration whereby the mammal transfers the sulfur of methionine via homocysteine to cysteine.
References Prochazka, Z., et al.: Collection Czechoslov. Chem. Commun., 45, 1982 (1980), Yorek, M.A. & Spector, A.A.: Prog. Clin. Biol. Res., 179, 361 (1985)

Applications Mequindox is an intermediate in the synthesis of Desoxyquinocetone which is a metabolite of the veterinay drug Quinocetone.
References Li, Y. et al.: J. AOAC Int., 91, 1494 (2008); Liu, Z.-Y. et al.: Anal. Bioanal. Chem., 396, 1259 (1271);

Stability Light Sensitive
Applications 2-Pentylidenecyclohexanone, is the fragrance chemical. It can also be used in the synthesis of dialkylphenols in the presence of zirconium catalyst.
References Tetsuo, B. et al.: Kenkyu Hokoku - Asahi Garasu Zaidan, 58, 201 (1991); Hostynek, J. J., et al.: Toxicology in Vitro, 11, 377 (1997);

Applications 4-​Ethoxy-​2,​3-​dihydroxy-​4-​oxobutanoic acid was studied for to be a possibe bifunctional gasoline-​methanol additive.
References Jiang, X., et al.: Asian J. Chem., 25, 8451-54 (2013);