Produits biochimiques et réactifs

<p>Applications Phenyl(9H-purin-6-yl)amine (cas# 1210-66-8) is a compound useful in organic synthesis.<br></p>

<p>Applications L-Threonolactone is formed in the autoxidation of L-Ascorbic acid (A786990), a compound that is essential for numerous enzymatic reactions in the body and is also responsible for scavenging free radicals to prevent oxidative damage to cells.<br>References Miyake, N., et al.: Biosci. Biotech. Bioch., 61, 2069 (1997); Kvernberg, P. &amp; Pedersen, B.: Acta Chem. Scand., 48, 646 (1994); Tsukaguchi, H., et al.: Nature, 399, 70 (1999)<br></p>

<p>Applications (S)-(-)-Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. (S)-(-)-Canadine has a strong central nervous system-depressing activity and is used in the preparation of tetrahydroprotoberberine derivatives as new antipsychotic agents.<br>References Sun, H. et al.: Bioorg. Med. Chem., 21, 856 (2013); Deeb, O., et al.: Chem. Biol. Drug Des., 76, 255 (2010); Sun., et al.: Br. J. Pharmcol., 158, 1302 (2009); Duchowicz, P., et al.: Bioorg. Med. Chem., 14, 5876 (2006); Yamahara, J. et al.: Chem. Pharm. Bull., 24, 1909 (1976)<br></p>

<p>Applications Glycolithocholic Acid Sodium Salt is a bile salt and may induce calcium uptake in human erythrocytes.<br>References Oelberg, D.G., et al.: Hepatology, 7 245-52 (1987);<br></p>

<p>Applications Naphthol Yellow S Hydrate is used in methods for dying of textiles.<br>References Schoepgens, J., et al.: Ger. Offen., (2020);<br></p>

<p>Applications An amino acid, first isolated from the juice of watermelon, Citrullus vulgaris Schrad., Cucurbitaceae. Used in the treatment of asthenia.<br>References Kurtz, et al.: J. Biol. Chem., 122, 477 (1938), Rajantie, J., et al.: J. Pediatr., 97, 927 (1980), Carpenter, T.O., et al.: N. Engl. J. Med., 312, 290 (1985),<br></p>

<p>Stability Hygroscopic<br>Applications L-Saccharopine is a product of breakdown of essential amino acid Lysine (L468895). Saccharopine is also part of the α-aminoadipate pathway of fungal lysine biosynthesis.<br>References Higashino, K., et al.: Biochem. Biophys. Res. Commun., 20, 285 (1965); Johansson, E., et al.: Structure, 8, 1037 (2000)<br></p>

<p>Applications 12-Hydroxylauric Acid is used in the structural and functional characterization of S-nitrosoglutathione reductase from Solanum lycopersicum.<br>References Kubienova, L., et. al.: Biochimie, 95, 889 (2013)<br></p>

<p>This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with EPA. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to EPA. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of EPA in the samples is then determined by comparing the OD of the samples to the standard curve.</p>

<p>This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with LTD4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to LTD4. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of LTD4 in the samples is then determined by comparing the OD of the samples to the standard curve.</p>

<p>Applications NF 279 is a potent and selective P2X1 antagonist.<br>References Kassack, M., et al.: Eur. J. Med. Chem., 39, 345 (2004); Damer, S., et al.: Eur. J. Pharm., 350, R5 (1998); Rettinger, J., et al.: Neuropharm., 39, 2044 (2000)<br></p>

<p>This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human LTE4. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LTE4. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human LTE4 in the samples is then determined by comparing the OD of the samples to the standard curve.</p>

<p>Applications Oleacein is one of the most abundant phenolic compounds of extra virgin olive oil and has antioxidant, anti-inflammatory, anti-proliferative, and antimicrobial activity. Oleacein may also be used as a potential antiatherosclerotic drug.<br>References Naruszewicz, M., et al.: Curr. Pharm. Design, 21, 1205 (2015); Vougogiannopoulou, K., et al.: J. Nat. Prod., 77, 441 (2014); Sindona, G., et al.: Curr. Med. Chem., 19, 4006 (2012)<br></p>

<p>Applications Poly(ethylene Glycol) ~400 is a polymer of ethylene oxide with a molecular weight of ~400 Daltons. Poly(ethylene Glycol) ~400 is considered a low molecular weight polyethylene glycol, and is used as a hydrophilic molecular probe for measuring intestinal permeability. Poly(ethylene Glycol) ~400 is also used as a hydrophilic plasticizer.<br>References Lu, E., et al.: J. Control. Release, 92, 375 (2003); Ma, T., et al.: Gastroenterology, 98, 39 (1990)<br></p>

<p>Stability Hygroscopic<br>Applications 1-O-Octadecanoyl-sn-glycerol is a monoacylglycerol (MAG) based saturated fatty acid derivative.<br>References Garcia, P. et al.: J. Sep. Sci., 34, 999 (2011); Takagi, T. et al.: LIpids, 25, 398 (1990);<br></p>

<p>The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human L-Carnitine. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human L-Carnitine. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human L-Carnitine, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human L-Carnitine in the samples is then determined by comparing the OD of the samples to the standard curve.</p>

<p>Applications A glycidol fatty acid esters in edible oils. An acyl acceptor for the unspecific bifunctional wax ester synthase/acyl-CoA:Diacylglycerol acyltransferase.<br>References Masukawa, Y. et al.: J. Am. Oil. Chem. Soc., 88, 15 (2011); Kalscheuer, R. et al.: Eur. J. Lipid. Sci. Tech., 105, 578 (2003)<br></p>

<p>Stability Hygroscopic<br>Applications 5,10-Diformyl-5,6,7,8-tetrahydrofolic acid is a derivative of the coenzyme 5,6,7,8-tetrahydrofolic acid which is essential in primary metabolism for reactions involving the transfer of a one-carbon unit at the formic acid, the formaldehyde or the methanol oxidation levels.<br>References Flaks, J.G., et al.: J. Biol. Chem., 228, 215 (1957),<br></p>