Antibiotiques
Les antibiotiques sont des composés conçus pour détruire ou inhiber la croissance de divers microorganismes, jouant un rôle crucial dans le traitement des infections et la prévention de la propagation des maladies. Cette catégorie offre une gamme diversifiée d'ingrédients actifs spécifiquement destinés à la recherche dans le domaine biochimique. Ces composés sont des outils essentiels pour étudier les mécanismes bactériens, les modèles de résistance et le développement de nouveaux agents thérapeutiques. Les chercheurs peuvent explorer une large variété d'antibiotiques pour comprendre leurs effets, optimiser leur utilisation et développer de nouveaux traitements pour combattre les menaces microbiennes émergentes. La disponibilité d'un spectre aussi large d'antibiotiques soutient la recherche avancée et l'innovation en microbiologie et en sciences pharmaceutiques.
Sous-catégories appartenant à la catégorie "Antibiotiques"
- Antibiotiques macrolides(26 produits)
- Antibiotiques stéroïdiens(31 produits)
- Antibiotiques de type tétracycline(20 produits)
- antibiotiques β-lactames(11 produits)
4102 produits trouvés pour "Antibiotiques"
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Decoyinine
CAS :Decoyinine is an antibiotic compound, which is derived from the bacterium *Streptomyces hygroscopicus*. Its mode of action involves the inhibition of guanine nucleotide synthesis. By targeting the biosynthesis pathway of nucleotides, Decoyinine effectively impedes the growth and proliferation of bacterial cells.Formule :C11H13N5O4Degré de pureté :Min. 95%Masse moléculaire :279.25 g/mol25-O-Deacetyl rifabutin
CAS :<p>25-O-Deacetyl rifabutin is an antibiotic derivative, which is sourced from the semi-synthetic modification of rifabutin, a compound originally derived from the fermentation of the bacterium Amycolatopsis mediterranei. This derivative works by inhibiting bacterial RNA synthesis. It achieves this by specifically targeting the DNA-dependent RNA polymerase enzyme, which is essential for bacterial transcription. The mechanism involves binding to the beta-subunit of the polymerase, thereby blocking the elongation of the RNA chain, which ultimately leads to the death of the bacterial cell.</p>Formule :C44H60N4O10Degré de pureté :Min. 95%Couleur et forme :Purple PowderMasse moléculaire :804.97 g/molCyclosporin L
CAS :<p>Cyclosporin L is an immunosuppressive agent, which is a cyclic polypeptide derived from the soil fungus Tolypocladium inflatum. It primarily functions by inhibiting the activity of calcineurin, a key phosphatase involved in the activation of T-cells. This inhibition prevents the transcription of interleukin-2 and other cytokines critical for T-cell proliferation.</p>Formule :C61H109N11O12Degré de pureté :90%MinMasse moléculaire :1,188.59 g/mol6'-N-Cbz-kanamycin A
CAS :<p>6'-N-Cbz-kanamycin A is a semi-synthetic aminoglycoside antibiotic derivative, specifically a Cbz (carbobenzyloxy) protected form of kanamycin A. It is derived from the natural product kanamycin, which is an antibiotic obtained from the bacterium *Streptomyces kanamyceticus*. The modification involves the introduction of a protective Cbz group at the 6' position, which can improve solubility, stability, or enable further chemical modifications.</p>Formule :C26H42N4O13Degré de pureté :Min. 95%Masse moléculaire :618.63 g/molClindamycin B hydrochloride
CAS :<p>Clindamycin B hydrochloride is a semi-synthetic antibiotic, which is derived from the parent compound, lincomycin, obtained from the bacterium *Streptomyces lincolnensis*. It exerts its antibacterial effects by binding to the 50S subunit of the bacterial ribosome, inhibiting protein synthesis by preventing peptide bond formation, which is essential for bacterial growth and survival.</p>Formule :C17H31ClN2O5S•HClDegré de pureté :Min. 95%Couleur et forme :White To Off-White SolidMasse moléculaire :447.42 g/molVirginiamycin - Complex of M1+S1
CAS :<p>Virginiamycin - Complex of M1+S1 is an antibiotic compound, which is derived from the actinobacterium Streptomyces virginiae. It functions through the inhibition of bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby obstructing peptide bond formation and impeding microbial growth. The complex is composed of two major components: Virginiamycin M1 and Virginiamycin S1, which synergistically enhance antimicrobial efficacy.</p>Formule :C71H84N10O17Degré de pureté :Min. 95%Masse moléculaire :1,349.48 g/molNarasin
CAS :<p>Narasin is an ionophore antibiotic, which is a fermentation product derived from certain strains of the bacterium *Streptomyces aureofaciens*. It functions by disrupting the ion gradients across cell membranes, specifically facilitating the transport of sodium and potassium ions. This action interferes with the energy metabolism of certain pathogenic microorganisms, rendering them unable to proliferate effectively.</p>Formule :C43H72O11Degré de pureté :Min. 95%Masse moléculaire :765.03 g/molPhleomycin
CAS :<p>Phleomycin is an antibiotic, which is derived from the bacterium *Streptomyces verticillus*. Its mode of action involves binding to DNA and inducing breaks by generating free radicals in the presence of oxygen and ferrous ions, leading to cell death. Phleomycin is prominently used in molecular biology applications as a selective agent in the generation of stable transfectants. It is particularly effective in selecting for cells that have integrated vectors conferring resistance, such as the Sh ble gene used in yeast, plant, and mammalian cell systems. Due to its potent DNA-cleaving ability, Phleomycin is valuable in studies requiring stringent selection pressure. Researchers commonly utilize it in experiments focusing on genetic modification and cellular resistance development.</p>Formule :C51H75N17O21S2Degré de pureté :Min. 95%Masse moléculaire :1,326.38 g/molTrovafloxacin mesylate
CAS :<p>Trovafloxacin mesylate is a synthetic antibiotic belonging to the fluoroquinolone class, which is derived from chemical synthesis processes rather than natural sources. The mode of action of trovafloxacin mesylate involves the inhibition of bacterial enzymes DNA gyrase and topoisomerase IV. These enzymes are essential for DNA replication, repair, and transcription within the bacterial cell. By inhibiting these enzymes, trovafloxacin mesylate disrupts bacterial DNA processes, leading to cell death and exerting its antibacterial effects.</p>Formule :C21H19F3N4O6SDegré de pureté :Min. 95%Masse moléculaire :512.46 g/molN-Biotinyl-12-aminododecanoyltobramycin amide
CAS :<p>N-Biotinyl-12-aminododecanoyltobramycin amide is a synthetic bioconjugate, which is derived from the aminoglycoside antibiotic tobramycin. This compound is chemically modified by the addition of a biotin moiety linked through a 12-aminododecanoyl spacer. The source of this product is rooted in the conjugation of biotin to tobramycin, allowing for targeted delivery and potential hybrid applications in both therapeutic and diagnostic fields.</p>Formule :C40H74N8O12SDegré de pureté :Min. 95%Masse moléculaire :891.13 g/molEnrofloxacin HCl
CAS :<p>Enrofloxacin HCl is a fluoroquinolone antibiotic, which is a synthetic compound derived from chemical synthesis. Its mode of action involves the inhibition of bacterial DNA gyrase and topoisomerase IV, critical enzymes in bacterial DNA replication and transcription processes. This action disrupts bacterial cellular division and transcription, leading to cell death.</p>Formule :C19H22FN3O3•HClDegré de pureté :Min. 95%Masse moléculaire :395.86 g/molTulathromycin B - 95%
CAS :<p>Inhibitor of protein synthesis; macrolide class</p>Formule :C41H79N3O12Degré de pureté :Min. 95%Masse moléculaire :806.08 g/molTigemonam
CAS :<p>Tigemonam is a synthetic beta-lactam antibiotic, which is derived from chemical synthesis processes. This compound operates by inhibiting bacterial cell wall synthesis, specifically targeting the penicillin-binding proteins (PBPs). The disruption of the cell wall synthesis ultimately leads to cell lysis and death of the bacteria, making it effective primarily against gram-negative bacterial infections.</p>Formule :C12H15N5O9S2Degré de pureté :Min. 95%Masse moléculaire :437.41 g/molCeftizoxime alapivoxil
CAS :Ceftizoxime alapivoxil is a prodrug antibiotic, which is derived from ceftizoxime, a third-generation cephalosporin. This semi-synthetic source enables the compound to effectively combat a wide range of bacterial infections by improving oral bioavailability compared to its parent compound. Once administered, ceftizoxime alapivoxil is metabolized in the body to release ceftizoxime, which exerts its antibacterial activity by binding to penicillin-binding proteins (PBPs) on bacterial cell walls. This binding action inhibits the transpeptidation step critical for cell wall synthesis, leading to cell lysis and bacterial death.Degré de pureté :Min. 95%Dequalinium chloride
CAS :<p>Dequalinium chloride is a novel, broad spectrum antimicrobial agent with a mechanism of action that inhibits the mitochondria-dependent respiratory chain. Studies have shown that it inhibits the growth of resistant microorganisms in cell-based experiments and in bacterial infections. Dequalinium chloride also has cytopathic effects on thp-1 cells, which are specific for Mycobacterium tuberculosis. In addition to inhibiting mitochondria-dependent respiration, this compound also increases acetylcholine receptor sensitivity in A549 lung cancer cells. Dequalinium chloride is a quaternary ammonium cation and has been shown to be effective against clinical isolates and inhibitory concentrations of a variety of virus species, including human rhinovirus (HRV) and Coxsackie virus type B4 (CoxB4).</p>Formule :C30H40Cl2N4Degré de pureté :Min. 95.0 Area-%Masse moléculaire :527.57 g/molClarithromycin - EP
CAS :<p>A macrolide, broad-spectrum antibiotic that targets cytochrome P4503A4 (CYP3A4). Clarithromycin has been used to potentiate the pharmacological effects of some drugs that are metabolised by the cytochrome P450.</p>Formule :C38H69NO13Degré de pureté :Min. 95%Masse moléculaire :747.95 g/molFosmidomycin sodium
CAS :<p>Fosmidomycin sodium is an antibiotic compound, which is derived from phosphonic acid. It functions as an inhibitor of the enzyme 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR), crucial in the non-mevalonate pathway of isoprenoid biosynthesis. By targeting this enzyme, fosmidomycin sodium disrupts the production of isoprenoids, essential components for the growth and survival of certain bacteria and parasites.</p>Formule :C4H9NNaO5PDegré de pureté :Min. 95%Masse moléculaire :205.08 g/molCeftarolin fosamil
CAS :<p>Ceftaroline fosamil is an advanced antibiotic, which is a cephalosporin derived from synthetic sources with a broad spectrum of activity. It is a prodrug that, once metabolized, becomes active in the body, binding to penicillin-binding proteins (PBPs) of bacteria. This binding inhibits the proteins responsible for cell wall synthesis, leading to bacterial cell lysis and death.</p>Formule :C22H21N8O8PS4Degré de pureté :Min. 95%Masse moléculaire :684.69 g/mol7-Descarbamoyl 17-amino geldanamycin
CAS :7-Descarbamoyl 17-amino geldanamycin is a semi-synthetic derivative of the benzoquinone ansamycin antibiotic geldanamycin, which is naturally produced by the bacterium *Streptomyces hygroscopicus*. As an inhibitor of the Heat Shock Protein 90 (Hsp90), it targets this molecular chaperone crucial for the stability and function of numerous oncoproteins. By inhibiting Hsp90, 7-Descarbamoyl 17-amino geldanamycin disrupts protein folding processes, leading to the degradation of client proteins and subsequent disruption of cell signaling pathways involved in tumor growth and survival.Formule :C27H38N2O7Degré de pureté :Min. 95%Masse moléculaire :502.6 g/molPC 190723
CAS :<p>PC 190723 is a synthetic chemical compound, which is derived through targeted chemical synthesis processes involving precise organic reactions. Its mode of action involves disrupting cellular division by inhibiting specific protein functions essential for the mitotic process. This molecular interaction results in potent effects on cell division, making it a valuable tool for studying cellular mechanics and developing therapeutic strategies.</p>Formule :C14H8ClF2N3O2SDegré de pureté :Min. 95%Masse moléculaire :355.75 g/mol
