Anticorps pour la recherche sur le cancer

This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse IFN-γ. Samples (or Standards) are added to the micro ELISA plate wells and combined with the specific antibody and biotinylated detection antibody specific for Mouse IFN-γ. Then Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Mouse IFN-γ, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm. The OD value is proportional to the concentration of Mouse IFN-γ. You can calculate the concentration of Mouse IFN-γ in the samples by comparing the OD of the samples to the standard curve.

This ELISA kit uses the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human sCD40L. Samples (or Standards) are added to the micro ELISA plate wells and combined with the specific antibody and biotinylated detection antibody specific for Human sCD40L. Then Avidin-Horseradish Peroxidase (HRP) conjugate are added successively to each micro plate well and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain Human sCD40L, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of stop solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm. The OD value is proportional to the concentration of Human sCD40L. You can calculate the concentration of Human sCD40L in the samples by comparing the OD of the samples to the standard curve.

<p>Bioymifi (DR5 Activator), a novel TRAIL activator, binds to DR5's ECD, inducing DR5 aggregation and stimulating cell apoptosis. Cost-effective and quality-assured.</p>

<p>Pinostilbene obviously attenuates the phosphorylation of c-Jun and JNK triggered by 6-OHDA.</p>

<p>Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.</p>

<p>Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-</p>

<p>MK-8033 is a new and selective dual ATP competitive c-Met/Ron inhibitor (IC50: 1 nM Wt c-Met).</p>

<p>I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.</p>

LJI308 is a potent, and pan-RSK (p90 ribosomal S6 kinase) inhibitor with IC50 of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.

<p>Alisertib (MLN 8237) is a specific Aurora A inhibitor (IC50: 1.2 nM). The selectivity of Alisertib(MLN 8237) is &gt;200-fold higher for Aurora A than Aurora B.</p>

<p>Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (</p>

<p>ARS-853 is an inhibitor of K-RASG12C(IC50 : 2.5 μM), a mutant form of K-RAS that accumulates in the active GTP-bound state in certain cancer cells</p>

<p>LYN-1604 is a novel ULK1 activator.It inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>

<p>Fursultiamine (Alinamin F) is a disulfide derivative of thiamine, or an allithiamine. It has potential uses in the treatment of vitamin B1 deficiency.</p>

<p>ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity.</p>

<p>Rhapontin may reduce liver fat and better blood sugar/lipids, showing potential for treating type 2 diabetes.</p>

<p>Ganoderic acid D, a Ganoderma component, inhibits HeLa cell growth with an IC50 of 17.3µM after 48h.</p>

ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).

<p>Fatostatin hydrobromide (Fatostatin A HBr), an inhibitor of sterol regulatory element binding protein (SREBP), impairs the activation of SREBP-1 and SREBP-2.</p>

<p>MSX-130 is CXCR4 Antagonist.</p>

<p>MSX-127 elicites positive response in peptide CXCR4.</p>

<p>CDIM8 (DIM-C-pPhOH) opposes NR4A1, halts TGF-β breast cancer migration, induces ROS/ER stress, and mimics Nur77 RNAi in pancreatic cancer.</p>

<p>(E/Z)-Zotiraciclib ((E/Z)-TG02) inhibits CDK2, JAK2, and FLT3 effectively with IC50s of 13, 73, and 56 nM, respectively.</p>

<p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>

<p>Cyclo(-RGDfK) is a selective and potent inhibitor of integrin αvβ3 with an IC50 value of 0.94 nM.Cost-effective and quality-assured.</p>

<p>Obatoclax Mesylate (GX15-070) is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and</p>

<p>(6R)-FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect.</p>

<p>Methyl caffeate (Methyl caffeate acid) acid</p>

<p>O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.</p>

<p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>

<p>Ketorolac (Acuvail) is an NSAID that blocks prostaglandin synthesis, related to heterocyclic acetic acids.</p>

<p>Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, and</p>

<p>MAT2A Inhibitor 4 acts as an inhibitor targeting the catalytic subunit of methionine S-adenosyltransferase-2 (MAT2A), offering potential utility in cancer</p>

<p>Pellitorine (Pellitorin) is an extract of Tetradium daniellii, and acts as a TRPV1 antagonist.</p>

<p>Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis.</p>

<p>Obtusifolin is an antioxidant that combats diabetes, bone-resorption, diabetic retinopathy, pain, and cognitive decline.</p>

<p>M2N12 selectively inhibits Cdc25C (IC50=0.09μM) and has anti-tumor properties, affecting Cdc25A and B as well.</p>

<p>ZCL278 is a selective Cdc42 GTPase inhibitor.</p>

<p>Almonertinib (HS-10296) is an inhibitor of EGFR activation mutation and tolerant mutation of EGFR T790M, which has only limited activity against wild-type EGFR.</p>

<p>Acetylalkannin (Alkannin acetate), an isohexenylnaphthazarin pigment extracted from Arnebia euchroma, exhibits antimicrobial and cytotoxic properties.</p>

<p>UNC2025 (mrx-6313)(IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor.</p>

<p>NVP-BVU972 is a selective and potent Met inhibitor with IC50 of 14 nM.</p>

<p>Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.</p>

<p>AG-270 is an allosteric and orally active inhibitor of MAT2A.</p>

<p>Thalidomide derivative compound 114 inhibits protomyosin receptor kinase, targets E3 ligase, potential for disease research.</p>

<p>HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.</p>

<p>(-)-Epipodophyllotoxin: anticancer, GI50=0.36μM (HeLa), 0.24μM (MCF-7), inhibits spindle assembly.</p>

<p>MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.</p>

<p>Neogambogic acid, an active ingredient in garcinia, can inhibit the growth of some solid tumors and result in an anticancer effect.</p>

<p>OTS514 hydrochloride is a highly effective TOPK(T-LAK cell-originated protein kinase) inhibitor (IC50: 2.6 nM).</p>