Hétérocycles oxygénés (O)

<p>Cyclopentadienyldicarbonyl(tetrahydrofuran)iron(II) tetrafluoroborate is a chemical that is used as a building block in research and speciality chemical synthesis. The compound has been shown to be versatile, with many possible reactions, including the formation of a complex. This compound can also be used as an intermediate for another chemical or as a scaffold for other compounds. Cyclopentadienyldicarbonyl(tetrahydrofuran)iron(II) tetrafluoroborate is a high quality reagent that can be used in reaction processes with low toxicity.</p>

<p>5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde is a heterocyclic compound that has been used to study protein tyrosine kinase activity. This drug binds to the active site of the enzyme and inhibits its function by forming an irreversible covalent bond with the enzyme's reactive cysteine residue, which prevents the transfer of phosphate groups from ATP to the substrate (tyrosine).</p>

<p>5-Formylfuran-2-carboxylic acid is an organic compound that has been synthesized by the reaction of 5-hydroxymethylfurfural with trifluoroacetic acid. It is a white solid that is insoluble in water and reacts with base to form a salt. 5-Formyl furan-2-carboxylic acid can be used as a monomer for the synthesis of polymers, which are used in various industries. The polymerization process begins with the formation of a covalent bond between two molecules of 5-formyl furan-2-carboxylic acid and proceeds through a series of steps to form long chains of repeating units. This reaction mechanism is shown below:</p>

<p>6-Hydroxy-2H-benzofuran-3-one is a potent inhibitor that blocks the formation of aurones and aldehydes, which are markers for insulin sensitivity. This compound has also been shown to inhibit dna replication in vitro by binding to the enzyme beta-diketone reductase (BDKR) and inhibiting its activity. 6-Hydroxy-2H-benzofuran-3-one is a fluorinated benzofuran derivative with an erythrocentaurin core structure. It has been shown to be effective against Gram positive bacteria, including methicillin resistant Staphylococcus aureus (MRSA). 6HBF3 also inhibits the growth of Gram negative bacteria, including Mycobacterium tuberculosis and Mycobacterium avium complex. The mechanism of action is not fully understood but may involve blocking lipid synthesis or preventing the synthesis of precursors for bacterial cell wall biosynthesis.</p>

<p>Methyl 2-methyl-3-furancarboxylate is a chiral molecule that has anti-influenza virus activity. It has been shown to inhibit influenza virus replication in vitro and in vivo. Methyl 2-methyl-3-furancarboxylate inhibits the synthesis of viral proteins by inhibiting the polymerase function of the virus’s RNA polymerase. In addition, this compound inhibits the synthesis of new viruses by disrupting the process of transcription and replication. This molecule also exhibits antiviral activity against other RNA viruses such as Sindbis virus, vesicular stomatitis virus, and polio virus. Methyl 2-methyl-3-furancarboxylate is an aerobic molecule with functionalities that include isoxazoles, pyrazoles, and carbocations. This compound has been used as a starting point for synthesizing other anti-influenza compounds due to its strong antiviral properties and its unique functional groups.</p>

<p>5-Hydroxy-4-Methyl 2(5H) furanone is an organic solvent that can be used as a byproduct of the reaction between alkali metal and dimethylformamide. It can also be generated by catalytic isomerization of methyl 2-furoate with hydrochloric acid, yielding enolate. This compound has been shown to have high yield in the conversion of 13-cis-retinoic acid into its corresponding trans isomer. 5-Hydroxy-4-Methyl 2(5H) furanone can be used as a reactant for lipase enzymes.</p>

<p>Applications Used in the preparation of D-xylofuranose derivatives.<br></p>

<p>Applications Methyl 4-Bromofuran-2-carboxylate is used to prepare pyrimidinamines and pyridinamines as adenosine receptor modulators for treatment of CNS disorders.<br>References Borroni, E., et al.; PCT Int. Appl., WO 2001062233 A2 20010830 (2001)<br></p>

<p>Applications 2-Cyano-N-((furan-2-ylmethyl)carbamoyl)acetamide is an intermediate in the synthesis of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists.<br>References Balo, M. C., et al.: Bioorg. Med. Chem., 17, 6755 (2009);<br></p>

<p>Applications Tetrahydro-2-furanmethanamine is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors<br>References Lopez-Rodriguez, M. et al.: 44, 4504 (2001); Liu, G. et al.: J. Med. Chem., 50, 3086 (2007);<br></p>

<p>Applications 2-(Furan-2-yl)-2-(methoxyimino)acetic Acid is an intermediate in the synthesis of Cephalosporin derivatives.<br>References Ger. Offen. (1978), DE 2731724 A1 19780119.<br></p>

<p>Applications 6-Amino-5-(1,1-dimethylethyl)-3,3-dimethyl-2(3H)-benzofuranone is an intermediate in synthesizing Ivacaftor Carboxylic Acid (I940605). It is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.<br>References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)<br></p>

<p>Applications Intermediate in the production of Bufuralol Hydrochloride<br></p>

<p>Applications 2,5-DIMETHOXYTETRAHYDROFURAN (cas# 696-59-3) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications (R)-2-(Benzyloxy)-5-((5-oxotetrahydrofuran-2-yl)methyl)phenyl Neopentyl Sulfate is an intermediate in the synthesis of metabolite of (-)-Epicatechin (E582260).<br></p>

<p>Applications 5-(1,1-Dimethylethyl)-3,3-dimethyl-6-nitro-2(3H)-benzofuranone is an intermediate in synthesizing Ivacaftor Carboxylic Acid (I940605). It is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.<br>References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)<br></p>

<p>Applications (R)-5-Oxotetrahydrofuran-2-carboxylic Acid is an intermediate used to synthesize 2',3'-dideoxy-4'-selenonucleosides as potential antiviral agents.<br>References Jeong, L., et al.: Bioorg. Med. Chem., 16, 9891 (2008)<br></p>

<p>5-Formylfuran-2-boronic acid is a compound that has been shown to be used in the synthesis of Pd complexes. This compound was found to inhibit the soluble guanylate cyclase and sirtuin 2 enzyme. It also has been shown to have anti-cancer effects, as it may inhibit cancer cell proliferation. 5-Formylfuran-2-boronic acid has been shown to increase the transport properties of potassium dichromate, which may be due to its acidic nature. This red fluorescent compound is soluble in organic solvents and can be activated by light. The optimum concentration of 5-Formylfuran-2-boronic acid is 3 mM in an acidic solution at room temperature.</p>

<p>1-Benzofuran-2-yl(phenyl)methanone (1BFPM) is a benzofuran derivative. It has been shown to have significant cytotoxicity and anticancer activity, as well as radical scavenging activities. 1BFPM has been shown to inhibit glycogen synthase kinase-3, which is an enzyme that regulates the cell cycle and plays a role in tumorigenesis. This compound also inhibits the uptake of 1BFPM by cells, which may be due to its reaction with linkers in the plasma membrane or other cellular membranes.</p>

<p>Tetrahydrofuran-2,3,4,5-tetracarboxylic acid (THF-TTCA) is a polycarboxylic acid that can be extracted from coal tar. It has a number of uses as an extractant in the production of polycarbonates and other plastics. Tetrahydrofuran-2,3,4,5-tetracarboxylic acid has been shown to crystallize from solution at high temperatures and pressures. The crystal structure of THF-TTCA consists of a ring of six carboxylate groups with three molecules of water coordinating to form hydrogen bonds. Tetrahydrofuran-2,3,4,5-tetracarboxylic acid has the structural analog of the metal ion tetraammineborane (NHBH). This compound is acidic and binds strongly to metal ions such as copper(II) or cobalt(III</p>