Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Bromo-4-tert-butyl-1-methyl-benzene (2BTMB) is a congener of polychlorinated biphenyls (PCBs). It is an oily liquid that is insoluble in water. 2BTMB is metabolized by the liver, and has been found in the blood, adipose tissue, and eggs of salmonids. 2BTMB has shown to have physicochemical properties that are similar to other PCB congeners. The toxicity of 2BTMB is largely unknown because it has not been extensively studied. 2BTMB can magnify up the food chain through bioaccumulation and biomagnification.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1-Bromo-4-cyclopentylbenzene (1-BCPB) is a chlorinated aromatic compound that can be synthesized by reacting 1-bromo-4-chlorobenzene and cyclopentylmagnesium bromide. The reaction sequence begins with the addition of hydrochloric acid to the first reactant, followed by magnesium chloride and ether. The mixture is heated to produce a liquid solution of ethylhexyloxy pyridine, which reacts with the second reactant in a sequence that leads to the desired product. 1-BCPB is used as an intermediate in organic synthesis. It has been shown to have moderate interaction with paraldehyde and pyridinium salts at room temperature, but it does not react with cycloalkyls or pyridinium salts at elevated temperatures.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Please enquire for more information about N,N-Dimethyl-2-(1-(1-(pyridin-2-yl)ethyl)-1H-inden-2-yl)ethan-1-amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Versatile small molecule scaffold

2-Bromo-1,3,5-triisopropylbenzene is an ethylene acetal that is prepared by the catalyzed reaction of aryl chlorides and anhydrous zinc bromide in the presence of triethylamine. The selectivities of this method are high because it can produce mainly a single isomer. The stereoselectivity is also high because the reaction proceeds with the formation of only one stereoisomer. The mechanism for this reaction involves a nucleophilic substitution of the halogenated aryl chloride with the trialkylborane, which generates two different products. This product has been used in the synthesis of biphenyls and nitro compounds.

1-(2-Methylphenyl)propan-2-amine is a fatty acid ester that is used as an excipient in pharmaceutical dosage forms. It is used to increase the viscosity of drug solutions and suspensions, and to provide a protective coating for tablets. 1-(2-Methylphenyl)propan-2-amine is insoluble in water, but soluble in organic solvents such as alcohols and acetone. It can be prepared by reacting a primary amine with a fatty acid chloride or anhydride. The compound has been shown to have high affinity for 5HT2A receptors in vitro, which may account for its psychoactive effects.

Rac-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-3-phenylpyrrolidine-2-carboxylic acid is a chiral, stereospecific, cyclic sulfate that is synthetized by the reaction of glycol with lactam. It has been found to be effective against various types of cancer cells. Rac-1-{[(9H-fluoren-9-yl)methoxy]carbonyl}-3-phenylpyrrolidine 2 carboxylic acid is an enantiopure compound that can be used as an intermediate in the synthesis of antiinflammatory drugs such as kainic acid.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Benzyne is a reactive intermediate that is formed by the tautomerization of 5-bromo-1,3-dimethylpyridin-2(1H)-one. It is an adduct between a bromine atom and a benzene ring. This compound has been shown to react with electron-rich olefins to form bicyclic compounds called diels-alder adducts. These reactions are often catalyzed by metals, such as palladium or nickel. Benzyne also reacts with triple bonds or other electron rich centers to form benzyne adducts, which are highly reactive and can be used as chemical probes for electron density in molecules.

Versatile small molecule scaffold

Versatile small molecule scaffold

1-(2-Methylpyridin-3-yl)ethanone is a ketone that can be synthesized using the reaction of methyl sulfone, benzyl sulfone, and sulphone. It has been shown to have anti-inflammatory properties by inhibiting prostaglandin synthesis and has been used as a nonsteroidal anti-inflammatory drug (NSAID). 1-(2-Methylpyridin-3-yl)ethanone has also been shown to have analgesic effects in mice. This synthetic compound may be useful in treating inflammation, pain, and fever.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2,4-Dibromo-6-nitroaniline is a nitro compound that has been used in the production of dyes. It is also used as a component in the synthesis of other organic compounds. 2,4-Dibromo-6-nitroaniline can be produced by electrolysis of an acid solution containing radical cations and benzene. The radical cations are formed by proton transfer from the acid to the benzene, followed by electron transfer from benzene to the electrode. This process results in the formation of nitro groups on the benzene ring, which undergoes oxidation to form 2,4-dibromo-6-nitroaniline. The cyclic voltammetry shows that this process occurs via two pathways: one with a fast rate and one with a slow rate. The mechanism for this reaction is not yet known.

2-Phenyl-1,3,4-oxadiazole is a 2-phenyloxazole with an oxygen atom at the 1 position. It is a white crystalline solid that is soluble in water and has antibacterial properties. This chemical can be used as a catalyst for the synthesis of organic compounds. 2-Phenyl-1,3,4-oxadiazole reacts with nitro groups to form oxime derivatives and has been shown to inhibit the growth of fungi such as Candida albicans and Aspergillus niger. 2-Phenyl-1,3,4-oxadiazole can also be used as an antifungal agent against Trichophyton rubrum.
2-Phenyl-1,3,4-oxadiazole may be synthesized by reacting phenol with acetone in the presence of nitric acid or sulfuric acid. The structural formula for this compound is

Please enquire for more information about 4,5-Dihydro-1H-imidazol-2-amine hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

1-Hydroxycyclopentane-1-carbonitrile is a monomer that is hydrolyzed to form benzoin and cyanohydrins. It can be used in the production of scifinder as a monomer or dimerizer.

Versatile small molecule scaffold

3-Hydroxy-5-methylpyridine (3HMP) is a chemical substance that has been classified as an amine. It is a product of the metabolism of purines, which are nitrogenous bases found in DNA and RNA. 3HMP is produced by aerogenic bacteria (such as Enterobacter), and can be used to estimate the number of these bacteria present in water samples. 3HMP has been shown to have antiviral properties against influenza virus, and can be used as a biomarker for the presence of other viruses in animals. 3HMP also has mineralization properties, which have been studied extensively, particularly with regards to pancreatic disease.

2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.

4,5-Dihydroxy-2,3-pentanedione is a carbonyl compound that is the product of the oxidation of ascorbic acid. It is used in wastewater treatment and has antimicrobial properties against infectious diseases. This compound has been shown to inhibit protein synthesis by binding to the ribosome and preventing the formation of peptide bonds between amino acids. 4,5-Dihydroxy-2,3-pentanedione has also been shown to bind to plasma proteins, which may be due to its acyl chain structure. 4,5-Dihydroxy-2,3-pentanedione can be synthesized in a catalytic mechanism that involves dehydroascorbic acid and molecular oxygen.

Piperyline is an alkanoic acid that has shown to be effective against skin cancer. It also has antimicrobial properties, which may be due to its ability to bind metal ions and form polymeric compounds. Piperyline inhibits microbial growth by inhibiting the synthesis of proteins and nucleic acids. The antimicrobial activity is related to its cationic polymerization with hydroxyl groups, which forms a structure that can inhibit microbial enzymes and disrupt microbial cell membranes. This compound also interacts with the skin's natural lipids, making it difficult for microorganisms to attach and grow on the skin. Piperyline is synthesized in organic chemistry laboratories as an amide precursor of other pharmaceuticals such as penicillin.