Building Blocks

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

2-Ethynyl-4-methoxypyridine is a pyridyl compound that can be prepared by the electrolysis of an azide in the presence of copper foil. It is a strong reducing agent and can be used to reduce other substances, such as carbonyls, to formic acid. 2-Ethynyl-4-methoxypyridine has been shown to catalyze the reduction of triazolyl compounds. This reaction proceeds through an electrochemical process in which 2-ethynyl-4-methoxypyridine reduces the triple bond. The nature of this reaction is photoreduction, in which a photon or electron from light or another source initiates the process.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

2,3,4,5-Tetrahydro-1-benzoxepine-3,5-dione is an intermediate in the synthesis of phenelzine. It is a benzyl derivative that can be synthesized from 2,3,4,5-tetrahydrobenzo[b]thiophene and isopropylmagnesium chloride. This compound has been shown to react with methoxy groups as well as sulfur and alkenyl groups. The reaction with nitro groups leads to the formation of an unstable nitroso compound. The compounds derived from this intermediate have been shown to have significant antibacterial activity against intestinal bacteria such as enterobacteriaceae and coliforms.

Versatile small molecule scaffold

5-Amino-1-methyl-1H-pyrazole-4-carbaldehyde (5AMPC) is a catalyst that activates alkyl groups. It is generated by the reaction of formaldehyde with cyanide. The cyanide group is then replaced by aminomethyl and cyano groups, which can be used in the synthesis of other organic compounds. 5AMPC has been extensively studied for its application as a catalyst in the production of nitriles from carbonyl compounds.

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Undec-10-en-1-amine is a chemical compound with the molecular formula C11H23N. It has a reactive chemical structure that can undergo reactions with other molecules. Undec-10-en-1-amine is used as a model system in carbohydrate chemistry and biological studies. It is also used in silicon polymerizations, glycopolymer synthesis, and primary amino acid synthesis. Undec-10-en-1-amine has been shown to be cytotoxic, which may be due to its ability to deaminate cytidine residues on DNA. This reaction results in the formation of uracil, which blocks RNA synthesis and leads to cell death.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>4-(Piperidin-4-yl)phenol is a potent antipsychotic drug that belongs to the group of piperidines. It has been shown to be active in animal models and as an antipsychotic agent in humans. 4-(Piperidin-4-yl)phenol binds to alpha and beta adrenergic receptors, serotonin receptors, dopamine receptors, and histamine H1 receptors. It has been shown to have high potency and affinity for these receptors. This drug is also cloned from human brain tissue and has acted as a subtype-selective antagonist at cloned human alpha 1A-adrenergic receptor.</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>1-(5-Phenylfuran-2-yl)ethan-1-one is a chemical compound that has been shown to be an effective method for synthesizing indole derivatives from 5-phenyl furan-2-carboxylic acid. The indole ring of the 1-(5-Phenylfuran-2-yl)ethan-1-one is derived from the furan ring, which is formed by a rearrangement of the carboxylic acid. This transformation can also be accomplished with other electrophilic reactants, such as thionyl chloride or phosphorus pentachloride. The synthesis of 1-(5-Phenylfuran-2-yl)ethan-1 can be achieved by the rearrangement of 2,3,4,5 tetrahydrofuran.<br>Synlett 2004, 1670</p>

3-Chloromethyl-4-methyl-furazan is a colorless liquid that is soluble in alcohol, ether and benzene. It has a boiling point of 104°C and an average molecular weight of 183.3. 3-Chloromethyl-4-methyl-furazan reacts with strong bases to form sulfuryl chloride, which is used as a precursor to other compounds. It can also be used for the chlorination of organic compounds or the manufacture of various sulfonyl chlorides.

7-Aminoheptanoic Acid Hydrochloride is a product that is obtained from the reaction of diethyl malonate with hydroxylamine. It is a nucleophilic compound that can react with various electrophiles, such as phthalimide. This product has high yields and can be used in organic synthesis to make other compounds. The crystallization of 7-Aminoheptanoic Acid Hydrochloride can be done by refluxing in hydrochloric acid and then decompressing the solution. The crystallizing agent used for this process can be either an organic solvent or water. This product can also be produced on a large scale using the malonate method.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

3,4-Dichloro-2(5H)-furanone is a biologically active compound that has been shown to inhibit the growth of Listeria monocytogenes and typhimurium. It is a furanone analog with a chlorine substituent on the 2 position. The chemical structure of 3,4-Dichloro-2(5H)-furanone includes an oxygenated hydroxyl group at the 4 position, which is important for its bacteriostatic effects. The compound has been shown to be effective against multidrug resistant strains of bacteria such as methicillin resistant Staphylococcus aureus (MRSA). 3,4-Dichloro-2(5H)-furanone also has biological properties that are similar to those of other furanones found in nature. This molecule exhibits spectrometric properties typical of many furanones and can be easily reduced by sodium borohyd

Versatile small molecule scaffold

Versatile small molecule scaffold

Methyl 5-bromo-2-oxopentanoate is a carbonyl compound that is used as an intermediate in organic synthesis. It can be used to make oxime, adduct, and attack compounds. Methyl 5-bromo-2-oxopentanoate reacts with hydroxylamine in the presence of acid to produce the corresponding oxime. In the presence of base, it reacts with proline to form an intramolecular acetylenedicarboxylate. This reaction takes place through a reductive elimination mechanism where hydrogenolysis is catalyzed by zinc metal or zinc chloride.

2-(Prop-2-en-1-yl)benzaldehyde is a synthetic, aldehydes, aromatic hydrocarbons and olefinic. It is an efficient method for the synthesis of the skeleton of alkene and anthracene. This compound can be used as a mediator in the reaction system, which has a high yield in reactions. It reacts with oxygenated ligands to form new molecules. 2-(Prop-2-en-1-yl)benzaldehyde is also a ligand that binds to receptor ligands such as riboflavin and pyridoxal phosphate.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-(Methoxymethyl)aniline is a chlorobenzene derivative with a methide group. It is prepared by the reaction of formamidines, xylene, and organometallics in high yields. The 2-methoxymethyl group is readily cleaved to form an amine, which can be used for the synthesis of other compounds. The bond cleavage occurs through deprotonation or proton abstraction to yield the desired product. This method provides a cheaper alternative to other methods that require expensive reagents like boron trifluoride etherate.</p>

2-(Chloromethyl)-4-methoxypyridine hydrochloride (2-CMP) is a sulfide that can be used as a catalyst in organic chemistry. 2-CMP is efficient for the conversion of alkenes to alkanes and has been shown to be selective for the formation of linear alkanes. The substituent effects on catalytic activity are sensitive to electronic effects, which may be due to the different electron densities of the sulfur atom. This compound has been shown to have high catalytic efficiency in converting hydrocarbons and can also be used as a catalyst in other reactions such as reductive amination, oxidation, and nitration.

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold