Building Blocks

Versatile small molecule scaffold

<p>N-Cyclobutyl-4-methylaniline is an organic compound that belongs to the class of imines. It is a nitrogen heterocycle with a 6-membered ring and an electron-deficient carbon atom. The molecule has two stereocenters and can be classified as both electrophilic and radical. N-Cyclobutyl-4-methylaniline is used as an intermediate in the synthesis of other compounds, such as diazepam (Valium).</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

N-Methoxy-N-methyl-3-phenylpropanamide is an organic compound that can be synthesized by asymmetric synthesis. It belongs to the group of heterocyclic compounds, and its molecular formula is C10H14NO2. The chemical name for this compound is 3-(2-methoxyethyl)-1-(3-phenylpropyl)pyrrolidine. This chemical has a ring system made up of one heterocyclic ring with two substituents. Its structure features a pyrrolidine, which is a type of amine with two carbonyl groups on adjacent carbon atoms. N-Methoxy-N-methyl-3-phenylpropanamide was first synthesized in 1964 by iodocyclization of 2-[(methylamino)methyl]benzonitrile and 1,1,1,2,2,2,-hexachloroethane. This process

<p>5-bromo-7-methylbenzofuran is an electron-rich heterocycle that can be activated by halides. It shows a high degree of electrophilicity and reacts readily with nucleophiles such as sulfur, nitrogen, oxygen, and the carbonyl group. 5-Bromo-7-methylbenzofuran is used in the synthesis of pharmaceuticals such as fluoxetine and ciprofloxacin. The aromatic system in 5-bromo-7-methylbenzofuran is composed of a benzene ring with two methyl groups on one side and a furan ring on the other side. Furfural is a natural product that can be synthesized from 5-bromo-7-methylbenzofuran.</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>H-DL-Arg-OH hydrochloride is a proton donor that stabilizes the plasma membrane in cells. It has been shown to inhibit the synthesis of active substances in erythrocytes and to reduce the rate of glucose uptake by these cells. The stability of H-DL-Arg-OH hydrochloride is increased by admixing with chloride salts, which may be due to its ability to form hydrochloride salts. This proton donor has also been shown to have an immune stimulating effect on cell cultures in vitro.</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>1,3-Di-tert-butyl cyclohexane-1,3-dicarboxylate is a fluorescent probe that senses metal cations. The fluorescence of 1,3-Di-tert-butyl cyclohexane-1,3-dicarboxylate changes in response to changes in the concentration of monovalent and divalent metal cations. This probe can be used to detect the presence of cations in various types of samples such as organic solvents and water. The probe’s fluorescence is proportional to the concentration of metal ions present, with a linear relationship between the change in fluorescence intensity and the change in ion concentration.</p>

<p>4-(4-Methylcyclohexyl)-4-oxobutanoic acid is a drug that enhances the effects of insulin on glucose uptake. It is a potent inhibitor of the ATP-sensitive potassium channels in pancreatic β cells, which leads to an increase in intracellular calcium and insulin secretion. 4-(4-Methylcyclohexyl)-4-oxobutanoic acid has been shown to be effective in treating type 2 diabetes mellitus in min6 cells and neonatal mice. This drug also has a potent effect on pancreatic β cells, leading to an increase in cellular proliferation and hormone release. 4-(4-Methylcyclohexyl)-4-oxobutanoic acid acts as an agonist for the l-type calcium channel, leading to increased extracellular calcium levels and an inhibition of potassium efflux from the cell.</p>

2,4,5-Trichlorophenylboronic acid is a drug substance that is used in the synthesis of imidazole derivatives. It has been shown to induce skin tumor formation when combined with caffeine and midodrine. 2,4,5-Trichlorophenylboronic acid has synergistic effects with other substances such as phorbol esters (e.g., 12-O-tetradecanoylphorbol 13-acetate) or c1-6 alkylating agents (e.g., ethylenimine).

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

4-Cyano-3-hydroxybenzoic acid (4C3HB) is a molecule that contains four methoxy groups and three hydroxyl groups. The molecule has been modified to include carboxy, hydroxy, and methoxy groups. 4C3HB can be synthesized by reacting 3-hydroxybenzoic acid with nitrous acid. This compound is a ligand of the enzyme cytochrome P450. 4C3HB is toxic to cells in vitro and has been shown to inhibit cellular respiration in mitochondria, which may be due to its ability to bind with cytochrome P450. The oral toxicity of this molecule is unknown, but it does not react with DNA or form adducts with proteins. It also does not cause any mutagenicity or carcinogenicity effects in mice.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,6-Dibromo-4-hydroxypyridine (2,6-DHP) is a low yield chemical compound that is used as an antimalarial agent. It is an epoxide that can be prepared by the Wittig reaction of 2,3-dibromopyridine with ethylene oxide. The population of 2,6-DHP has been shown to have enantiopure properties in the synthesis of pyridines and ring-opening reactions with primary amines. This compound also has low spin and solvates.</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>3-(Methylsulfonyl)benzyl alcohol is a ketone that inhibits the catalytic hydrogenation of benzyl groups. It also has been shown to be an antagonist of β-adrenergic receptors. 3-(Methylsulfonyl)benzyl alcohol is used as a catalyst in catalytic bromination and has also been shown to have anti-inflammatory properties.</p>

<p>Versatile small molecule scaffold</p>

<p>4-hydroxy-6-(propan-2-yl)-2H-pyran-2-one is a recombinant molecule made in the laboratory. It is a substrate for recombinant escherichia coli, which are then used to produce large quantities of the molecule. 4-hydroxy-6-(propan-2-yl)-2H-pyran-2-one is also known as an intermediate in the synthesis of other compounds and has been shown to inhibit bacterial growth at high concentrations.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

Versatile small molecule scaffold