Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Chloro-5-phenyloxazole is an organic compound that belongs to the class of c2-6 alkenyl, acyloxyalkyl, and formyl compounds. It is also a carboxylic acid derivative. 2-Chloro-5-phenyloxazole has been shown to be active against bacteria such as Staphylococcus aureus and Pseudomonas aeruginosa. This drug has been shown to have antibacterial properties against a variety of organisms, including gram positive and gram negative bacteria.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-Chloro-N-methyl-2-nitroaniline is an antibiotic that belongs to the group of quinolone antibiotics. It has a broad spectrum against Gram-positive and Gram-negative bacteria, including methicillin resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. 3-Chloro-N-methyl-2-nitroaniline binds to bacterial DNA gyrase and topoisomerase IV, as well as human DNA gyrase and topoisomerase II, inhibiting their activity. This leads to cell death by interfering with the production of proteins vital for cell division. The optimal parameters for this drug have been found using isothermal titration calorimetry on the enzyme gyrase in the presence of different concentrations of 3CMA. Pharmacological targets for this drug include DNA gyrase and topoisomerase IV.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Quinoline-5-carbonitrile is a cyanide compound that can be used in the synthesis of heterocyclic compounds. The reaction between quinoline and 5-cyanovaleric acid produces 6-nitroquinoline, which is then converted to dimethyl sulfoxide by alcoholysis. This reaction product can then be used to synthesize an amide or nucleophile. Quinoline-5-carbonitrile reacts with potassium in the presence of bifunctional hydrazide to produce a cyanide ion, which can be hydrolyzed by an acid to release hydrogen cyanide gas. This experiment has been shown as a model for reactions involving cyano compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-(2-Methylphenyl)-2-sulfanyl-4,5-dihydro-1H-imidazol-5-one is a cross linking agent that is used in the production of polyurethanes. It is derived from 2,2'-oxydiethanol and can be used as a polymerization catalyst for polyurethane resins. 1-(2-Methylphenyl)-2-sulfanyl-4,5-dihydro-1H-imidazol-5 -one has been shown to have antibacterial properties against gram positive bacteria such as Staphylococcus aureus and Streptococcus pneumoniae. The antibacterial activity was attributed to its ability to form covalent bonds with carboxylic acid groups on the bacterial cell wall.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Bicyclo[4.1.0]heptan-7-ylmethanol is a hydride inhibitor of lactate dehydrogenase, which is an enzyme that catalyzes the conversion of pyruvate to lactate in the liver. Bicyclo[4.1.0]heptan-7-ylmethanol has inhibitory properties against aldehyde dehydrogenase and alcohol dehydrogenase, which are enzymes involved in the metabolism of aldehydes and alcohols respectively. This substance also inhibits mitochondrial monoamine oxidase (MAO), which is an enzyme that breaks down neurotransmitters such as dopamine, norepinephrine, and serotonin. Bicyclo[4.1.0]heptan-7-ylmethanol can be used to inhibit the function of MAO in order to increase levels of these neurotransmitters in the brain, which may be helpful for conditions like depression or Parkinson</p>

<p>1-Benzothiophene-6-carboxylic acid is a nicotinic acetylcholine receptor agonist that has been shown to have high oral bioavailability and efficacy in vivo. It binds to the α7 nicotinic acetylcholine receptor and activates the receptor, leading to increased neurotransmitter release. 1-Benzothiophene-6-carboxylic acid has been shown to be effective in vivo in models of neuropathic pain and Parkinson's disease. This drug also has a low affinity for other receptors, such as muscarinic acetylcholine receptors, which reduces the chance of adverse effects.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Iodo-4-methoxybenzaldehyde is a chiral compound that can be synthesized through an intramolecular, stereoselective cyclic annulation reaction. The key step in this process is the arylation of 2-iodo-4-methoxybenzaldehyde with ethyl bromide. This compound can also be synthesized by reacting 2-iodobenzoic acid with formaldehyde in the presence of a base. In addition, 2-Iodo-4-methoxybenzaldehyde can be produced by the sequence of nitrogen substitution and tricyclic annulation.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1-Chloro-3-ethylpentan-2-one is a chemical compound that contains a nitrogen atom and is classified as an organic compound. It has been used in the synthesis of other chemicals including pharmaceuticals, herbicides, and plastics. This chemical has been shown to hydrate at 180 degrees Celsius to form a nitrite salt. It can be used as an orienting agent for synthesizing other compounds.</p>

<p>Versatile small molecule scaffold</p>

<p>2-Acetylbenzoic acid is a functional molecule that contains an acetyl group. It can form hydrogen bonds with other molecules and has been shown to induce apoptosis in cells. The reaction products of 2-acetylbenzoic acid are malonic acid, acetylsalicylic acid, and 2-benzoylbenzoic acid. These three compounds are made by the addition of hydrogen or hydroxide to the molecule 2-acetylbenzoic acid. The molecule has two functional groups: a carbonyl group and an acetyl group. The chemical structure of this molecule can be seen in the figure below.<br>2-Acetylbenzoic Acid</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Please enquire for more information about 1-[3-(Dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-3-oxo-5-isobenzofurancarbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Phenoxyaniline is a nitro compound that can be converted to the corresponding palladium complexes. It is an inhibitor of the acylation reaction, which is a type of chemical reaction in which an organic molecule reacts with an acid. The inhibition of this reaction has been shown to have an effect on heart disease, specifically by lowering cholesterol levels and reducing atherosclerosis. 2-Phenoxyaniline has also been shown to inhibit the activation energy for electron transfer reactions, making it useful as a catalyst in analytical methods. 2-Phenoxyaniline also undergoes vibrational spectroscopy when exposed to liquid chromatography and other analytical methods.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2,2',4,4'-tetrahydroxybenzophenone is a hydroxylated benzophenone that has immunomodulatory effects. It binds to the receptor in the immune system and can cause an increase in cytokine production. 2,2',4,4'-tetrahydroxybenzophenone is cytotoxic and has significant toxicity in vitro. The molecule has been shown to disrupt mitochondrial membrane potential. This may be due to its ability to form hydrogen bonds with molecules on the mitochondrial membrane. 2,2',4,4'-tetrahydroxybenzophenone also modulates transcriptional regulation of genes involved in cell proliferation and apoptosis. The drug is detectable at low levels by mass spectrometry and is not known to have any toxicological effects.END&gt;&gt;</p>

<p>3-Methylbenzo[b]thiophene-2-carboxylic acid (MBTCA) is a heterocyclic compound that is an intermediate in the synthesis of 3-methylthiophene-2-carboxylic acid, a precursor to other drugs. MBTCA is an aerobic, nonpolar compound that has shown antimicrobial activity against some bacteria and fungi. It also has been shown to have practicality as a biomolecular probe for methyl groups in organic solvents. MBTCA can be synthesized by nitration of benzene in the presence of sulfur and sulfoxides. This reaction produces nitrobenzene, which can then be oxidized by potassium permanganate or hydrogen peroxide to produce MBTCA. The most common isomer of MBTCA is 2-(3,5-dimethoxybenzylidene)tetrahydrofuran, with three methyl groups on the</p>

<p>2-Bromo-3,3,3-trifluoro-1-propene is a chemical compound that has been synthesized in an asymmetric reaction. The reactant is bromopropane and the product is 2,2,2-trifluoropropene. The methylene group on the propene molecule is activated by the nucleophilic attack of a fluoride ion from hydrogen fluoride to form a cavity with a highly strained bond. The kinetic study of this reaction revealed that the activation energy for the reaction is 42 kJ/mol. Palladium-catalyzed coupling reactions are catalyzed by palladium and require nonpolar solvents such as toluene or dichloromethane. This type of reaction has been shown to be exothermic with an isolated yield of 1%.</p>

<p>Versatile small molecule scaffold</p>

<p>Please enquire for more information about H-Ser-Ala-Glu-Glu-Tyr-Glu-Tyr-Pro-Ser OH trifluoroacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Givinostat hydrochloride is a research chemical that has shown potential in various fields. It is a molybdenum-based compound that has been studied for its effects on dopamine release and hydrogen evolution. Givinostat hydrochloride has also been investigated as an osteoclast inhibitor, which may be beneficial in the treatment of bone-related disorders such as osteoporosis. Additionally, it has shown promise as a retinoid and calpain inhibitor, suggesting its potential use in dermatological conditions and neurodegenerative diseases. The compound contains fluorine atoms, making it suitable for imaging studies using fluorine MRI techniques. Givinostat hydrochloride has been tested on MDA-MB-231 cells and has shown inhibitory effects on their growth, indicating its potential as an anticancer agent.</p>