Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1,3-Dimethyl-6-amino-1H-indazole is a hydrogen bond donor and the skeleton is planar. It has been shown to be a potential drug for the treatment of neurodegenerative diseases.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>3-(1H-Indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione is a neuroprotective agent that has shown anti-inflammatory properties in a number of animal models. The compound inhibits the production of proinflammatory cytokines and chemokines through its inhibition of phosphoinositide 3 kinase (PI3K) and nuclear factor kappa B (NFκB). 3-(1H-Indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione also inhibits proliferation in different types of cancer cells. It is structurally related to indoleamine 2,3 dioxygenase (IDO), which is an enzyme that breaks down tryptophan into kynurenine. IDO inhibitors have been shown to be neuroprotective in animal models. In addition, this compound has been found</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>8-bromo-3,4-dihydro-1H-2-benzopyran is a research chemical that falls under the category of piperazines. This compound is known for its regioisomeric properties, which means it can exist in different structural forms. Researchers use 8-bromo-3,4-dihydro-1H-2-benzopyran to study its effects and potential applications in various fields. Its unique structure makes it an interesting compound for scientific exploration and experimentation.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

3-(4-Ethylphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde is a potent and selective agonist of the α2A adrenergic receptor. It has been used as an experimental tool to study the function of this receptor and its role in different biological processes. This compound also acts as an antagonist of the α2B adrenergic receptor, which may be due to its ability to inhibit protein synthesis. 3-(4-Ethylphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde has a high purity level and can be synthesized in large quantities at a low cost.

PI-103 is a potent inducer of apoptosis. It has low potency and is selective for solid tumours, such as breast cancer. PI-103 inhibits the mitochondrial membrane potential by binding to the voltage-dependent anion channel (VDAC) in the outer mitochondrial membrane. PI-103 also inhibits protein synthesis and induces cell death by activating caspase 9 and caspase 3. PI-103 is also used to treat viral infections, such as hepatitis C virus, and bacterial infections, including tuberculosis.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5-Benzyl-1,2-oxazole-3-carboxylic acid is a novel compound that interacts with the NOD2 protein to inhibit inflammatory responses in cells. It has been shown to be effective against colitis and other inflammatory diseases in animal models. The compound has a high potency and acts by inhibiting the production of proinflammatory cytokines such as TNFα and IL-1β. It also inhibits spontaneous inflammations in rats and humans, highlighting its therapeutic potential for treatment of inflammatory diseases. 5-Benzyl-1,2-oxazole-3-carboxylic acid is orally bioavailable and has been found to be well tolerated at doses up to 2000 mg/kg. This drug is currently being optimized for use as a therapy for inflammatory bowel disease (IBD).</p>

Versatile small molecule scaffold

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

XantPhos Pd G4 is a synthetic, inorganic base that has been used in the synthesis of a variety of drugs. XantPhos Pd G4 is an analog of L-arginine and has been shown to have anti-inflammatory properties. It inhibits the production of inflammatory cytokines and growth factors, which may be due to its ability to bind to proteins involved in the regulation of inflammation. XantPhos Pd G4 also blocks the function of factor receptors that are responsible for the development and progression of autoimmune diseases.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

1-imino-1lambda6-thiomorpholin-1-one is a synthetic drug that belongs to the class of sulfones. It has been used as a medicinal and chemical reagent, with applications in drug discovery, synthesis, and medicinal chemistry. 1-imino-1lambda6-thiomorpholin-1-one is an accessible molecule that can be synthesized from commercially available starting materials using simple reactions. The compound has been shown to have substituent effects at the n-alkyl position. Additionally, it is isosteric with the sulfoximine group, making it an attractive candidate for substitution with other groups that are not compatible with sulfoximines.

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>