Building Blocks

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

2-Methyl-2-propylpentanoic acid is an organic compound that belongs to the class of primary alcohols with a chemical formula CH3(CH2)5COOH. It is an acidic, fatty acid ester that can be synthesized by methylation of pentanoic acid. 2-Methyl-2-propylpentanoic acid has been used as a preservative in food and cosmetics, but it is also used as an intermediate for pharmaceuticals and other organic compounds. The use of 2-methyl-2-propylpentanoic acid as a solvent has been limited because it is highly reactive and corrosive to metal surfaces. This product can react with other compounds to produce new products, such as hippuric acid or citric acid. One theory about the mechanism of this reaction suggests that the reaction proceeds through a free radical chain mechanism.

Tributyl(methoxymethyl)stannane is a synthetic organo-tin compound that has antifungal, antiviral, and antibacterial properties. It is also used in the treatment of idiopathic pulmonary fibrosis, hepatitis, cirrhosis, heart disease, and scleroderma. Tributyl(methoxymethyl)stannane inhibits the synthesis of proteins by binding to the 30S ribosomal subunit through a number of mechanisms. It has been shown to inhibit the growth of many fungi including those that cause athlete's foot and ringworm. Tributyl(methoxymethyl)stannane also shows some promise as an anti-inflammatory agent.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Cyclopropyl isocyanate (CPC) is an aliphatic hydrocarbon that is structurally similar to butane. Cyclopropyl isocyanate has a variety of functional groups including a hydroxy group, a serine protease, and an amino group. CPC has been shown to be a potent activator of the enzyme histone h3 lysine 4 trimethyltranferase, which is involved in the regulation of inflammatory diseases. The synthesis of cyclopropyl isocyanate can be done through the reaction with diazomethane and zinc chloride or by treating 1-chlorocyclohexene with nitrous acid.

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

Versatile small molecule scaffold

1,2,5,6,7,8-Hexahydroquinoxalin-2-one is a stimulant that has been shown to be effective for the prophylaxis and/or treatment of diabetes. It is also a prophylactic agent for the prevention of pyrazinone. This drug has been shown to stimulate insulin secretion from pancreatic beta cells in vitro. 1,2,5,6,7,8-Hexahydroquinoxalin-2-one stimulates the release of insulin by stimulating exocytosis and inhibiting vesicle fusion in response to glucose. It can also inhibit or stimulate the release of insulin in response to other stimuli such as amino acids and fatty acids.